SCOPUS 정보 검색 플랫폼

Journal of Computer-Aided Molecular Design

Volumn 23, Issue 12, 2009, Pages 883-895

Cardio-vascular safety beyond hERG: In silico modelling of a guinea pig right atrium assay

(8) Fenu, Luca A a Teisman, Ard a De Buck, Stefan S b Sinha, Vikash K a Gilissen, Ron A H J a Nijsen, Marjoleen J M A c MacKie, Claire E a Sanderson, Wendy E a

a JANSSEN RESEARCH AND DEVELOPMENT (Belgium)

b NOVARTIS PHARMA AG (Switzerland)

c ABBOTT GMBH AND CO KG (Germany)

Author keywords

Cardio vascular safety; Computational; HERG; In silico; In vitro

Indexed keywords

ASSAYS; IONS; KNOWLEDGE BASED SYSTEMS; PHYSIOLOGICAL MODELS; STATISTICAL TESTS;

CARDIO VASCULAR SAFETY; COMPUTATIONAL; GUINEA PIGS; HERG; HIGH CAPACITY; HIGH-CAPACITY; IN-SILICO; IN-SILICO MODELS; IN-VITRO; ION CHANNEL;

DIGITAL STORAGE;

POTASSIUM CHANNEL HERG;

ACCURACY; ARTICLE; AUTOMATION; BAYESIAN LEARNING; BINDING ASSAY; CARDIOVASCULAR FUNCTION; COMPUTER MODEL; CONTROLLED STUDY; GUINEA PIG; HEART CONTRACTION; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE REFRACTORY PERIOD; HEART RIGHT ATRIUM; HIGH THROUGHPUT SCREENING; ISOLATED HEART; KNOWLEDGE BASE; LIPOPHILICITY; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; SENSITIVITY AND SPECIFICITY;

EID: 76449114545 PISSN: 0920654X EISSN: 15734951 Source Type: Journal
DOI: 10.1007/s10822-009-9306-z Document Type: Article

Times cited : (4)

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