Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643)

Molecular Pharmacology

Volumn 69, Issue 1, 2006, Pages 266-277

  Hansen, Rie Schultz ^a,b   Diness, Thomas Goldin ^a,b   Christ, Torsten ^c   Demnitz, Joachim ^a   Ravens, Ursula ^c   Olesen, Søren Peter ^a,b   Grunnet, Morten ^a,b  

^a NEUROSEARCH A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; 1,3 BIS (2 HYDROXY 5 TRIFLUOROMETHYL PHENYL) UREA; DIPHENYLUREA; NS 1643; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL HERG; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ACTION POTENTIAL; ANIMAL CELL; ANTIARRHYTHMIC ACTIVITY; ARTICLE; ATTENUATION; CELL STRAIN HEK293; CONTROLLED STUDY; DEPOLARIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRIC POTENTIAL; EMBRYO; FEMALE; GUINEA PIG; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN EMBRYO; ISCHEMIA; KIDNEY CELL; NONHUMAN; OOCYTE; PATCH CLAMP; PRIORITY JOURNAL; REENTRY ARRHYTHMIA; REPOLARIZATION; STEADY STATE; XENOPUS LAEVIS;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; CALCIUM; CELL LINE; CRESOLS; ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; MYOCARDIAL CONTRACTION; MYOCARDIUM; PHENYLUREA COMPOUNDS; SODIUM; XENOPUS LAEVIS;

EID: 30044441212     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.105.015859     Document Type: Article

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