메뉴 건너뛰기




Volumn 78, Issue 22, 2004, Pages 12395-12405

Perforin and Fas act together in the induction of apoptosis, and both are critical in the clearance of lymphocytic choriomeningitis virus infection

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; GAMMA INTERFERON; GRANZYME A; GRANZYME B; PERFORIN; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE;

EID: 7644243776     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.22.12395-12405.2004     Document Type: Article
Times cited : (22)

References (65)
  • 1
    • 0028856130 scopus 로고
    • Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver
    • Adachi, M., S. Suematsu, T. Kondo, J. Ogasawara, T. Tanaka, N. Yoshida, and S. Nagata. 1995. Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver. Nat. Genet. 11:294-300.
    • (1995) Nat. Genet. , vol.11 , pp. 294-300
    • Adachi, M.1    Suematsu, S.2    Kondo, T.3    Ogasawara, J.4    Tanaka, T.5    Yoshida, N.6    Nagata, S.7
  • 3
    • 0035831462 scopus 로고    scopus 로고
    • Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition
    • Alimonti, J. B., L. Shi, P. K. Bayai, and A. H. Greenberg. 2001. Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition. J. Biol. Chem. 276:6974-6982.
    • (2001) J. Biol. Chem. , vol.276 , pp. 6974-6982
    • Alimonti, J.B.1    Shi, L.2    Bayai, P.K.3    Greenberg, A.H.4
  • 5
    • 0037621465 scopus 로고    scopus 로고
    • Potentiation of Fas-mediated apoptosis by attenuated production of mitochondria-derived reactive oxygen species
    • Aronis, A., J. A. Melendez, O. Golan, S. Shilo, N. Dicter, and O. Tirosh. 2003. Potentiation of Fas-mediated apoptosis by attenuated production of mitochondria-derived reactive oxygen species. Cell Death Differ. 10:335-344.
    • (2003) Cell Death Differ. , vol.10 , pp. 335-344
    • Aronis, A.1    Melendez, J.A.2    Golan, O.3    Shilo, S.4    Dicter, N.5    Tirosh, O.6
  • 7
    • 0036595397 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes: All roads lead to death
    • Barry, M., and R. C. Bleackley. 2002. Cytotoxic T lymphocytes: all roads lead to death. Nat. Rev. Immunol. 2:401-409.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 401-409
    • Barry, M.1    Bleackley, R.C.2
  • 8
    • 0025883707 scopus 로고
    • Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates
    • Errata, 35:115, 1991; 38:263, 1992
    • Battegay, M., S. Cooper, A. Althage, J. Banziger, H. Hengartner, and R. M. Zinkernagel. 1991. Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates. J. Virol. Methods 33:191-198. (Errata, 35:115, 1991; 38:263, 1992.)
    • (1991) J. Virol. Methods , vol.33 , pp. 191-198
    • Battegay, M.1    Cooper, S.2    Althage, A.3    Banziger, J.4    Hengartner, H.5    Zinkernagel, R.M.6
  • 9
    • 0035136852 scopus 로고    scopus 로고
    • Granzyme A and B-deficient killer lymphocytes are defective in eliciting DNA fragmentation but retain potent in vivo anti-tumor capacity
    • Davis, J. E., M. J. Smyth, and J. A. Trapani. 2001. Granzyme A and B-deficient killer lymphocytes are defective in eliciting DNA fragmentation but retain potent in vivo anti-tumor capacity. Eur. J. Immunol. 31:39-47.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 39-47
    • Davis, J.E.1    Smyth, M.J.2    Trapani, J.A.3
  • 12
    • 0037423932 scopus 로고    scopus 로고
    • Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor
    • Fan, Z., P. J. Beresford, D. Y. Oh, D. Zhang, and J. Lieberman. 2003. Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. Cell 112:659-672.
    • (2003) Cell , vol.112 , pp. 659-672
    • Fan, Z.1    Beresford, P.J.2    Oh, D.Y.3    Zhang, D.4    Lieberman, J.5
  • 15
    • 0033577852 scopus 로고    scopus 로고
    • Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte
    • Guidotti, L. G., P. Borrow, A. Brown, H. McClary, R. Koch, and F. V. Chisari. 1999. Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte. J. Exp. Med. 189:1555-1564.
    • (1999) J. Exp. Med. , vol.189 , pp. 1555-1564
    • Guidotti, L.G.1    Borrow, P.2    Brown, A.3    McClary, H.4    Koch, R.5    Chisari, F.V.6
  • 17
    • 0024416820 scopus 로고
    • Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A
    • Hayes, M. P., G. A. Berrebi, and P. A. Henkart. 1989. Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A. J. Exp. Med. 170:933-946.
    • (1989) J. Exp. Med. , vol.170 , pp. 933-946
    • Hayes, M.P.1    Berrebi, G.A.2    Henkart, P.A.3
  • 18
    • 0022308091 scopus 로고
    • Mechanism of lymphocyte-mediated cytotoxicity
    • Henkart, P. A. 1985. Mechanism of lymphocyte-mediated cytotoxicity. Annu. Rev. Immunol. 3:31-58.
    • (1985) Annu. Rev. Immunol. , vol.3 , pp. 31-58
    • Henkart, P.A.1
  • 19
    • 0028258577 scopus 로고
    • Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
    • Heusel, J. W., R. L. Wesselschmidt, S. Shresta, J. H. Russell, and T. J. Ley. 1994. Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 76:977-987.
    • (1994) Cell , vol.76 , pp. 977-987
    • Heusel, J.W.1    Wesselschmidt, R.L.2    Shresta, S.3    Russell, J.H.4    Ley, T.J.5
  • 22
    • 0021934271 scopus 로고
    • Mechanism of recovery from acute virus infection. I. Role of T lymphocytes in the clearance of lymphocytic choriomeningitis virus from spleens of mice
    • Lehmann-Grube, F., U. Assmann, C. Loliger, D. Moskophidis, and J. Lohler. 1985. Mechanism of recovery from acute virus infection. I. Role of T lymphocytes in the clearance of lymphocytic choriomeningitis virus from spleens of mice. J. Immunol. 134:608-615.
    • (1985) J. Immunol. , vol.134 , pp. 608-615
    • Lehmann-Grube, F.1    Assmann, U.2    Loliger, C.3    Moskophidis, D.4    Lohler, J.5
  • 23
    • 0036122356 scopus 로고    scopus 로고
    • Lack of both Fas ligand and perform protects from flavivirus-mediated encephalitis in mice
    • Licon Luna, R. M., E. Lee, A. Müllbacher, R. V. Blanden, R. Langman, and M. Lobigs. 2002. Lack of both Fas ligand and perform protects from flavivirus-mediated encephalitis in mice. J. Virol. 76:3202-3211.
    • (2002) J. Virol. , vol.76 , pp. 3202-3211
    • Licon Luna, R.M.1    Lee, E.2    Müllbacher, A.3    Blanden, R.V.4    Langman, R.5    Lobigs, M.6
  • 24
    • 0028262942 scopus 로고
    • Murine hepatitis caused by lymphocytic choriomeningitis virus. I. The hepatic lesions
    • Lohler, J., J. Gossmann, T. Kratzberg, and F. Lehmann-Grube. 1994. Murine hepatitis caused by lymphocytic choriomeningitis virus. I. The hepatic lesions. Lab. Investig. 70:263-278.
    • (1994) Lab. Investig. , vol.70 , pp. 263-278
    • Lohler, J.1    Gossmann, J.2    Kratzberg, T.3    Lehmann-Grube, F.4
  • 25
    • 0033521626 scopus 로고    scopus 로고
    • Mitochondria-dependent and -independent regulation of granzyme B-induced apoptosis
    • MacDonald, G., L. Shi, C. Vande Velde, J. Lieberman, and A. H. Greenberg. 1999. Mitochondria-dependent and -independent regulation of granzyme B-induced apoptosis. J. Exp. Med. 189:131-144.
    • (1999) J. Exp. Med. , vol.189 , pp. 131-144
    • MacDonald, G.1    Shi, L.2    Vande Velde, C.3    Lieberman, J.4    Greenberg, A.H.5
  • 26
    • 0029808217 scopus 로고    scopus 로고
    • Differential inhibition of the Fas- and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein
    • Macen, J. L., R. S. Garner, P. Y. Musy, M. A. Brooks, P. C. Turner, R. W. Moyer, G. McFadden, and R. C. Bleackley. 1996. Differential inhibition of the Fas- and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein. Proc. Natl. Acad. Sci. USA 93:9108-9113.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9108-9113
    • Macen, J.L.1    Garner, R.S.2    Musy, P.Y.3    Brooks, M.A.4    Turner, P.C.5    Moyer, R.W.6    McFadden, G.7    Bleackley, R.C.8
  • 27
    • 0037451224 scopus 로고    scopus 로고
    • Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis
    • Metkar, S. S., B. Wang, M. L. Ebbs, J. H. Kim, Y. J. Lee, S. M. Raja, and C. J. Froelich. 2003. Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis. J. Cell Biol. 160:875-885.
    • (2003) J. Cell Biol. , vol.160 , pp. 875-885
    • Metkar, S.S.1    Wang, B.2    Ebbs, M.L.3    Kim, J.H.4    Lee, Y.J.5    Raja, S.M.6    Froelich, C.J.7
  • 28
    • 0345517173 scopus 로고    scopus 로고
    • Poxvirus-encoded serpins do not prevent cytolytic T cell-mediated recovery from primary infections
    • Müllbacher, A., R. Wallich, R. W. Moyer, and M. M. Simon. 1999. Poxvirus-encoded serpins do not prevent cytolytic T cell-mediated recovery from primary infections. J. Immunol. 162:7315-7321.
    • (1999) J. Immunol. , vol.162 , pp. 7315-7321
    • Müllbacher, A.1    Wallich, R.2    Moyer, R.W.3    Simon, M.M.4
  • 29
    • 0033598718 scopus 로고    scopus 로고
    • Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes
    • Müllbacher, A., P. Waring, R. T. Hia, T. Tran, S. Chin, T. Stehle, C. Museteanu, and M. M. Simon. 1999. Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes. Proc. Natl. Acad. Sci. USA 96:13950-13955.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 13950-13955
    • Müllbacher, A.1    Waring, P.2    Hia, R.T.3    Tran, T.4    Chin, S.5    Stehle, T.6    Museteanu, C.7    Simon, M.M.8
  • 30
    • 0037261142 scopus 로고    scopus 로고
    • Concerted action of perforin and granzymes is critical for the elimination of Trypanosoma cruzi from mouse tissues, but prevention of early host death is in addition dependent on the FasL/Fas pathway
    • Muller, U., V. Sobek, S. Balkow, C. Holscher, A. Mullbacher, C. Museteanu, H. Mossmann, and M. M. Simon. 2003. Concerted action of perforin and granzymes is critical for the elimination of Trypanosoma cruzi from mouse tissues, but prevention of early host death is in addition dependent on the FasL/Fas pathway. Eur. J. Immunol. 33:70-78.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 70-78
    • Muller, U.1    Sobek, V.2    Balkow, S.3    Holscher, C.4    Mullbacher, A.5    Museteanu, C.6    Mossmann, H.7    Simon, M.M.8
  • 31
    • 0034630317 scopus 로고    scopus 로고
    • Apoptotic DNA fragmentation
    • Nagata, S. 2000. Apoptotic DNA fragmentation. Exp. Cell Res. 256:12-18.
    • (2000) Exp. Cell Res. , vol.256 , pp. 12-18
    • Nagata, S.1
  • 32
    • 0028980902 scopus 로고
    • Fas and Fas ligand: lpr and gld mutations
    • Nagata, S., and T. Suda. 1995. Fas and Fas ligand: lpr and gld mutations. Immunol. Today 16:39-43.
    • (1995) Immunol. Today , vol.16 , pp. 39-43
    • Nagata, S.1    Suda, T.2
  • 33
    • 0036312429 scopus 로고    scopus 로고
    • The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells
    • Pardo, J., S. Balkow, A. Anel, and M. M. Simon. 2002. The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells. Eur. J. Immunol. 32:1980-1985.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 1980-1985
    • Pardo, J.1    Balkow, S.2    Anel, A.3    Simon, M.M.4
  • 34
    • 0036773613 scopus 로고    scopus 로고
    • Granzymes are essential for natural killer cell-mediated and perf-facilitated tumor control
    • Pardo, J., S. Balkow, A. Anel, and M. M. Simon. 2002. Granzymes are essential for natural killer cell-mediated and perf-facilitated tumor control. Eur. J. Immunol. 32:2881-2887.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2881-2887
    • Pardo, J.1    Balkow, S.2    Anel, A.3    Simon, M.M.4
  • 35
    • 0033975075 scopus 로고    scopus 로고
    • Contributions of Fas-Fas ligand interactions to the pathogenesis of mouse hepatitis virus in the central nervous system
    • Parra, B., M. T. Lin, S. A. Stohlman, C. C. Bergmann, R. Atkinson, and D. R. Hinton. 2000. Contributions of Fas-Fas ligand interactions to the pathogenesis of mouse hepatitis virus in the central nervous system. J. Virol. 74:2447-2450.
    • (2000) J. Virol. , vol.74 , pp. 2447-2450
    • Parra, B.1    Lin, M.T.2    Stohlman, S.A.3    Bergmann, C.C.4    Atkinson, R.5    Hinton, D.R.6
  • 36
    • 0033986159 scopus 로고    scopus 로고
    • + cell granules, restricts the spread of herpes simplex virus in the peripheral nervous systems of experimentally infected mice
    • + cell granules, restricts the spread of herpes simplex virus in the peripheral nervous systems of experimentally infected mice. J. Virol. 74:1029-1032.
    • (2000) J. Virol. , vol.74 , pp. 1029-1032
    • Pereira, R.A.1    Simon, M.M.2    Simmons, A.3
  • 38
    • 0022574278 scopus 로고
    • Molecular mechanisms of cytolysis by complement and by cytolytic lymphocytes
    • Podack, E. R. 1986. Molecular mechanisms of cytolysis by complement and by cytolytic lymphocytes. J. Cell. Biochem. 30:133-170.
    • (1986) J. Cell. Biochem. , vol.30 , pp. 133-170
    • Podack, E.R.1
  • 39
    • 0034033438 scopus 로고    scopus 로고
    • Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection
    • Riera, L, M. Gariglio, G. Valente, A. Mullbacher, C. Museteanu, S. Landolfo, and M. M. Simon. 2000. Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection. Eur. J. Immunol. 30:1350-1355.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 1350-1355
    • Riera, L.1    Gariglio, M.2    Valente, G.3    Mullbacher, A.4    Museteanu, C.5    Landolfo, S.6    Simon, M.M.7
  • 40
    • 0036217977 scopus 로고    scopus 로고
    • Lymphocyte-mediated cytotoxicity
    • Russell, J. H., and T. J. Ley. 2002. Lymphocyte-mediated cytotoxicity. Annu. Rev. Immunol. 20:323-370.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 323-370
    • Russell, J.H.1    Ley, T.J.2
  • 41
    • 0033524857 scopus 로고    scopus 로고
    • A comparative study of apoptosis and necrosis in HepG2 cells: Oxidant-induced caspase inactivation leads to necrosis
    • Samali, A., H. Nordgren, B. Zhivotovsky, E. Peterson, and S. Orrenius. 1999. A comparative study of apoptosis and necrosis in HepG2 cells: oxidant-induced caspase inactivation leads to necrosis. Biochem. Biophys. Res. Commun. 255:6-11.
    • (1999) Biochem. Biophys. Res. Commun. , vol.255 , pp. 6-11
    • Samali, A.1    Nordgren, H.2    Zhivotovsky, B.3    Peterson, E.4    Orrenius, S.5
  • 42
    • 0026474805 scopus 로고
    • Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions
    • Shi, L., C. M. Kam, J. C. Powers, R. Aebersold, and A. H. Greenberg. 1992. Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions. J. Exp. Med. 176:1521-1529.
    • (1992) J. Exp. Med. , vol.176 , pp. 1521-1529
    • Shi, L.1    Kam, C.M.2    Powers, J.C.3    Aebersold, R.4    Greenberg, A.H.5
  • 43
    • 0026532606 scopus 로고
    • A natural killer cell granule protein that induces DNA fragmentation and apoptosis
    • Shi, L., R. P. Kraut, R. Aebersold, and A. H. Greenberg. 1992. A natural killer cell granule protein that induces DNA fragmentation and apoptosis. J. Exp. Med. 175:553-566.
    • (1992) J. Exp. Med. , vol.175 , pp. 553-566
    • Shi, L.1    Kraut, R.P.2    Aebersold, R.3    Greenberg, A.H.4
  • 44
    • 0030802988 scopus 로고    scopus 로고
    • Residual cytotoxicity and granzyme K expression in granzyme A-deficient cytotoxic lymphocytes
    • Shresta, S., P. Goda, R. Wesselschmidt, and T. J. Ley. 1997. Residual cytotoxicity and granzyme K expression in granzyme A-deficient cytotoxic lymphocytes. J. Biol. Chem. 272:20236-20244.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20236-20244
    • Shresta, S.1    Goda, P.2    Wesselschmidt, R.3    Ley, T.J.4
  • 45
    • 0033136315 scopus 로고    scopus 로고
    • Granzyme A initiates an alternative pathway for granule-mediated apoptosis
    • Shresta, S., T. A. Graubert, D. A. Thomas, S. Z. Raptis, and T. J. Ley. 1999. Granzyme A initiates an alternative pathway for granule-mediated apoptosis. Immunity 10:595-605.
    • (1999) Immunity , vol.10 , pp. 595-605
    • Shresta, S.1    Graubert, T.A.2    Thomas, D.A.3    Raptis, S.Z.4    Ley, T.J.5
  • 46
    • 0030723209 scopus 로고    scopus 로고
    • In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A X B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells
    • Simon, M. M., M. Hausmann, T. Tran, K. Ebnet, J. Tschopp, R. ThaHla, and A. Mullbacher. 1997. In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A X B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells. J. Exp. Med. 186:1781-1786.
    • (1997) J. Exp. Med. , vol.186 , pp. 1781-1786
    • Simon, M.M.1    Hausmann, M.2    Tran, T.3    Ebnet, K.4    Tschopp, J.5    Thahla, R.6    Mullbacher, A.7
  • 47
    • 0034292398 scopus 로고    scopus 로고
    • Cytotoxic T cells specifically induce Fas on target cells, thereby facilitating exocytosis-independent induction of apoptosis
    • Simon, M. M., P. Waring, M. Lobigs, A. Nil, T. Tran, R. T. Hla, S. Chin, and A. Mullbacher. 2000. Cytotoxic T cells specifically induce Fas on target cells, thereby facilitating exocytosis-independent induction of apoptosis. J. Immunol. 165:3663-3672.
    • (2000) J. Immunol. , vol.165 , pp. 3663-3672
    • Simon, M.M.1    Waring, P.2    Lobigs, M.3    Nil, A.4    Tran, T.5    Hla, R.T.6    Chin, S.7    Mullbacher, A.8
  • 48
    • 0021270071 scopus 로고
    • Aged marine killer T-cell clones acquire specific cytotoxicity for P815 mastocytoma cells
    • Simon, M. M., H. U. Weltzien, H. J. Buhring, and K. Eichmann. 1984. Aged marine killer T-cell clones acquire specific cytotoxicity for P815 mastocytoma cells. Nature 308:367-370.
    • (1984) Nature , vol.308 , pp. 367-370
    • Simon, M.M.1    Weltzien, H.U.2    Buhring, H.J.3    Eichmann, K.4
  • 49
    • 0034572835 scopus 로고    scopus 로고
    • NKT cells and tumor immunity - A double-edged sword
    • Smyth, M. J., and D. I. Godfrey. 2000. NKT cells and tumor immunity - a double-edged sword. Nat. Immunol. 1:459-460.
    • (2000) Nat. Immunol. , vol.1 , pp. 459-460
    • Smyth, M.J.1    Godfrey, D.I.2
  • 50
    • 0038107576 scopus 로고    scopus 로고
    • Cutting edge: Granzymes A and B are not essential for perforin-mediated tumor rejection
    • Smyth, M. J., S. E. Street, and J. A. Trapani. 2003. Cutting edge: granzymes A and B are not essential for perforin-mediated tumor rejection. J. Immunol. 171:515-518.
    • (2003) J. Immunol. , vol.171 , pp. 515-518
    • Smyth, M.J.1    Street, S.E.2    Trapani, J.A.3
  • 51
    • 0036740213 scopus 로고    scopus 로고
    • Antigen-induced cell death of T effector cells in vitro proceeds via the Fas pathway, requires endogenous interferon-gamma and is independent of perforin and granzymes
    • Sobek, V., S. Balkow, H. Korner, and M. M. Simon. 2002. Antigen-induced cell death of T effector cells in vitro proceeds via the Fas pathway, requires endogenous interferon-gamma and is independent of perforin and granzymes. Eur. J. Immunol. 32:2490-2499.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2490-2499
    • Sobek, V.1    Balkow, S.2    Korner, H.3    Simon, M.M.4
  • 53
    • 0030785790 scopus 로고    scopus 로고
    • The central executioner of apoptosis: Multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis
    • Susin, S. A., N. Zamzami, M. Castedo, E. Daugas, H. G. Wang, S. Geley, F. Fassy, J. C. Reed, and G. Kroemer. 1997. The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis. J. Exp. Med. 186:25-37.
    • (1997) J. Exp. Med. , vol.186 , pp. 25-37
    • Susin, S.A.1    Zamzami, N.2    Castedo, M.3    Daugas, E.4    Wang, H.G.5    Geley, S.6    Fassy, F.7    Reed, J.C.8    Kroemer, G.9
  • 55
    • 0037341354 scopus 로고    scopus 로고
    • Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors
    • Sutton, V. R., M. E. Wowk, M. Cancilla, and J. A. Trapani. 2003. Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors. Immunity 18:319-329.
    • (2003) Immunity , vol.18 , pp. 319-329
    • Sutton, V.R.1    Wowk, M.E.2    Cancilla, M.3    Trapani, J.A.4
  • 56
    • 0032526940 scopus 로고    scopus 로고
    • The regulation of reactive oxygen species production during programmed cell death
    • Tan, S., Y. Sagara, Y. Liu, P. Maher, and D. Schubert. 1998. The regulation of reactive oxygen species production during programmed cell death. J. Cell Biol. 141:1423-1432.
    • (1998) J. Cell Biol. , vol.141 , pp. 1423-1432
    • Tan, S.1    Sagara, Y.2    Liu, Y.3    Maher, P.4    Schubert, D.5
  • 57
    • 0029120118 scopus 로고
    • CrmA, a poxvirus-encoded serpin, inhibits cytotoxic T-lymphocyte-mediated apoptosis
    • Tewari, M., W. G. Telford, R. A. Miller, and V. M. Dixit. 1995. CrmA, a poxvirus-encoded serpin, inhibits cytotoxic T-lymphocyte-mediated apoptosis. J. Biol. Chem. 270:22705-22708.
    • (1995) J. Biol. Chem. , vol.270 , pp. 22705-22708
    • Tewari, M.1    Telford, W.G.2    Miller, R.A.3    Dixit, V.M.4
  • 58
    • 0036779576 scopus 로고    scopus 로고
    • Functional significance of the perforin/granzyme cell death pathway
    • Trapani, J. A., and M. J. Smyth. 2002. Functional significance of the perforin/granzyme cell death pathway. Nat. Rev. Immunol. 2:735-747.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 735-747
    • Trapani, J.A.1    Smyth, M.J.2
  • 59
    • 0029946043 scopus 로고    scopus 로고
    • Fas mediates apoptosis in human monocytes by a reactive oxygen intermediate dependent pathway
    • Um, H. D., J. M. Orenstein, and S. M. Wahl. 1996. Fas mediates apoptosis in human monocytes by a reactive oxygen intermediate dependent pathway. J. Immunol. 156:3469-3477.
    • (1996) J. Immunol. , vol.156 , pp. 3469-3477
    • Um, H.D.1    Orenstein, J.M.2    Wahl, S.M.3
  • 61
    • 0029616324 scopus 로고
    • Perform dependence of natural killer cell-mediated tumor control in vivo
    • van den Broek, M. F., D. Kagi, R. M. Zinkernagel, and H. Hengartner. 1995. Perform dependence of natural killer cell-mediated tumor control in vivo. Eur. J. Immunol. 25:3514-3516.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3514-3516
    • Van Den Broek, M.F.1    Kagi, D.2    Zinkernagel, R.M.3    Hengartner, H.4
  • 64
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie, A. H. 1980. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284:555-556.
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 65
    • 0022497854 scopus 로고
    • Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity
    • Young, J. D., H. Hengartner, E. R. Podack, and Z. A. Cohn. 1986. Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity. Cell 44:849-859.
    • (1986) Cell , vol.44 , pp. 849-859
    • Young, J.D.1    Hengartner, H.2    Podack, E.R.3    Cohn, Z.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.