Granzyme A and B-deficient killer lymphocytes are defective in eliciting DNA fragmentation but retain potent in vivo anti-tumor capacity

European Journal of Immunology

Volumn 31, Issue 1, 2001, Pages 39-47

  Torán, José Luis ^a,b   Sánchez Pulido, Luis ^b   Kremer, Leonor ^a   Del Real, Gustavo ^a   Valencia, Alfonso ^b   Martínez A, Carlos ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

Granzyme AB deficiency; Perforin deficiency; Tumor rejection

Indexed keywords

3 METHYLCHOLANTHRENE; DNA FRAGMENT; GRANZYME A; GRANZYME B; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PERFORIN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DEATH; CELL LINE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME DEFICIENCY; GRAFT VERSUS HOST REACTION; IN VIVO STUDY; MOUSE; NATURAL KILLER CELL; NONHUMAN; ORTHOPOXVIRUS; PRIORITY JOURNAL; SPLEEN CELL; TUMOR REJECTION;

EID: 0035136852     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200101)31:1<39::AID-IMMU39>3.0.CO;2-1     Document Type: Article

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