메뉴 건너뛰기




Volumn 89, Issue 2, 1996, Pages 205-212

Fas-induced programmed cell death is mediated by a Ras-regulated O2- synthesis

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; FAS ANTIGEN; GLUTATHIONE; SUPEROXIDE;

EID: 0029826849     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1996.d01-743.x     Document Type: Article
Times cited : (72)

References (69)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide range implications in tissue kinetics
    • KERR J.F.R., WYLLIE A.H. & CURRIE A.R. (1972) Apoptosis: a basic biological phenomenon with wide range implications in tissue kinetics. Br J Cancer 26, 239.
    • (1972) Br J Cancer , vol.26 , pp. 239
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 3
    • 0026504147 scopus 로고
    • Social controls on cell survival and cell death
    • RAFF M.C. (1992) Social controls on cell survival and cell death. Nature 356, 397.
    • (1992) Nature , vol.356 , pp. 397
    • Raff, M.C.1
  • 5
    • 0028353492 scopus 로고
    • The TNF-receptor superfamily of cellular and viral proteins: Activation. costimulation, and death
    • SMITH C.A., FARRAH T. & GOODWIN R.G. (1994) The TNF-receptor superfamily of cellular and viral proteins: activation. costimulation, and death. Cell 76, 959.
    • (1994) Cell , vol.76 , pp. 959
    • Smith, C.A.1    Farrah, T.2    Goodwin, R.G.3
  • 6
    • 0028277663 scopus 로고
    • Unraveling function in the TNF ligand and receptor families
    • BEUTLER B. & VAN HUFFEL C. (1994) Unraveling function in the TNF ligand and receptor families. Science 264, 667.
    • (1994) Science , vol.264 , pp. 667
    • Beutler, B.1    Van Huffel, C.2
  • 7
    • 0025916387 scopus 로고
    • The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
    • ITOH N., YONEHARA S., ISHII A. et al. (1991) The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66, 233.
    • (1991) Cell , vol.66 , pp. 233
    • Itoh, N.1    Yonehara, S.2    Ishii, A.3
  • 8
    • 0026706261 scopus 로고
    • Purification and molecular cloning of the APO-I cell surface antigen, a member of the tumor necrosis factor nerve growth factor receptor super-family: Sequence identity with the Fas antigen
    • OEHM A., BEHRMANN I., WEIH F. et al. (1992) Purification and molecular cloning of the APO-I cell surface antigen, a member of the tumor necrosis factor nerve growth factor receptor super-family: sequence identity with the Fas antigen. J Biol Chem 267, 10709.
    • (1992) J Biol Chem , vol.267 , pp. 10709
    • Oehm, A.1    Behrmann, I.2    Weih, F.3
  • 9
    • 0029032472 scopus 로고
    • Lipid hydroperoxide-induced apoptosis: Lack of inhibition by Bcl2-overexpression
    • SANDSTROM P.A., PARDI D., TEBBEY P.W. et al. (1995) Lipid hydroperoxide-induced apoptosis: lack of inhibition by Bcl2-overexpression FEBS Lett 365, 66.
    • (1995) FEBS Lett , vol.365 , pp. 66
    • Sandstrom, P.A.1    Pardi, D.2    Tebbey, P.W.3
  • 11
    • 0029101644 scopus 로고
    • Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
    • ZAMZAMI N., MARCHETTI P., CASTEDO M. et al. (1995) Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med 182, 367.
    • (1995) J Exp Med , vol.182 , pp. 367
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3
  • 12
    • 0028176651 scopus 로고
    • Redox regulation of programmed cell death in lymphocytes
    • BUTTKE T.M. & SANDSTROM P.A. (1994) Redox regulation of programmed cell death in lymphocytes. Immunol Today 15, 7.
    • (1994) Immunol Today , vol.15 , pp. 7
    • Buttke, T.M.1    Sandstrom, P.A.2
  • 13
    • 0027717968 scopus 로고
    • Bcl2-inhibition of neural death decreased generation of reactive oxygen species
    • KANE D.J., SARAFIAN T.A., ANTON R. et al. (1993) Bcl2-inhibition of neural death decreased generation of reactive oxygen species. Science 262, 1274.
    • (1993) Science , vol.262 , pp. 1274
    • Kane, D.J.1    Sarafian, T.A.2    Anton, R.3
  • 14
    • 0028115871 scopus 로고
    • 2 stimulate mitogen activated protein kinase activity in NIH-3T3-cells through the formation of reactive oxygen intermediates
    • 2 stimulate mitogen activated protein kinase activity in NIH-3T3-cells through the formation of reactive oxygen intermediates. Cancer Res 54, 12.
    • (1994) Cancer Res , vol.54 , pp. 12
    • Stevenson, M.A.1    Pollock, S.S.2    Coleman, C.N.3    Calderwood, S.K.4
  • 15
    • 0028964917 scopus 로고
    • Fas induced apoptosis is mediated via a ceramide-initiated Ras signaling pathway
    • GULBINS E., BISSONETTE R., MABOUBI A. et al. (1995) Fas induced apoptosis is mediated via a ceramide-initiated Ras signaling pathway. Immunity 2, 341.
    • (1995) Immunity , vol.2 , pp. 341
    • Gulbins, E.1    Bissonette, R.2    Maboubi, A.3
  • 17
    • 0028095477 scopus 로고
    • Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase
    • CIFONE M.G., DEMARIA R., RONCALI P. et al. (1994) Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J Exp Med 180, 1547.
    • (1994) J Exp Med , vol.180 , pp. 1547
    • Cifone, M.G.1    Demaria, R.2    Roncali, P.3
  • 18
    • 0029148660 scopus 로고
    • Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
    • BOSE R., VERHEIJ M., HAIMOVITZ-FRIEDMAN A., SCOTTO K., FUKS Z. & KOLESNICK R. (1995) Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell 82, 405.
    • (1995) Cell , vol.82 , pp. 405
    • Bose, R.1    Verheij, M.2    Haimovitz-Friedman, A.3    Scotto, K.4    Fuks, Z.5    Kolesnick, R.6
  • 19
    • 0026524523 scopus 로고
    • DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement
    • OWEN-SCHAUB L., YONEHARA S., CRUMP W. & GRIMM E.A. (1992) DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement. Cell Immunol 140, 197.
    • (1992) Cell Immunol , vol.140 , pp. 197
    • Owen-Schaub, L.1    Yonehara, S.2    Crump, W.3    Grimm, E.A.4
  • 20
    • 0028485743 scopus 로고
    • The fas antigen is involved in peripheral but not thymic deletion of T-lymphocytes in T-cell receptor transgenic mice
    • SINGER G.G. & ABBAS A.K. (1994) The fas antigen is involved in peripheral but not thymic deletion of T-lymphocytes in T-cell receptor transgenic mice. Immunity 1, 365.
    • (1994) Immunity , vol.1 , pp. 365
    • Singer, G.G.1    Abbas, A.K.2
  • 21
    • 0028980902 scopus 로고
    • Fas and Fas ligand: Lpr and gld mutations
    • NAGATA S. & SUDA T. (1995) Fas and Fas ligand: lpr and gld mutations. Immunol Today 16, 39.
    • (1995) Immunol Today , vol.16 , pp. 39
    • Nagata, S.1    Suda, T.2
  • 22
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in fas antigen that mediates apoptosis
    • WATANABE-FUKUNAGA R., BRANNAN C.I., COPELAND N.G., JENKINS N.A. & NAGATA S. (1992) Lymphoproliferation disorder in mice explained by defects in fas antigen that mediates apoptosis. Nature 356, 314.
    • (1992) Nature , vol.356 , pp. 314
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 23
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice caused by a point mutation in the Fas ligand
    • TAKAHASHI T., TANAKA M., BRANNAN C.I. et al. (1994) Generalized lymphoproliferative disease in mice caused by a point mutation in the Fas ligand. Cell 76, 969.
    • (1994) Cell , vol.76 , pp. 969
    • Takahashi, T.1    Tanaka, M.2    Brannan, C.I.3
  • 24
    • 0028206729 scopus 로고
    • Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in T cells transgenic MRL-lpr/lpr mice
    • WU J., ZHOU T., ZHANG J., HE J., GAUSE W.C. & MOUNTZ J.D. (1994) Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in T cells transgenic MRL-lpr/lpr mice. Proc Natl Acad Sci USA 91, 2344.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2344
    • Wu, J.1    Zhou, T.2    Zhang, J.3    He, J.4    Gause, W.C.5    Mountz, J.D.6
  • 25
    • 0029006893 scopus 로고
    • Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
    • RIEUX-LAUCAT F., LEDEIST F., HIVROZ C. et al. (1995) Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 268, 1347.
    • (1995) Science , vol.268 , pp. 1347
    • Rieux-Laucat, F.1    Ledeist, F.2    Hivroz, C.3
  • 26
    • 0029025441 scopus 로고
    • Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
    • FISHER G.H., ROSENBERG F.J., STRAUS S.E. et al. (1995) Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 81, 935.
    • (1995) Cell , vol.81 , pp. 935
    • Fisher, G.H.1    Rosenberg, F.J.2    Straus, S.E.3
  • 27
    • 0029029058 scopus 로고
    • Sensitization of T-cells to CD95 mediated apoptosis by HIV-1 Tat and gp120
    • WESTENDORP M.A., FRANK R., OCHSENBAUER C. et al. (1995) Sensitization of T-cells to CD95 mediated apoptosis by HIV-1 Tat and gp120. Nature 375, 497.
    • (1995) Nature , vol.375 , pp. 497
    • Westendorp, M.A.1    Frank, R.2    Ochsenbauer, C.3
  • 28
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid beta protein toxicity
    • BEHL C., DAVIS J.B., LESLEY R. & SCHUBERT D. (1994) Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 77, 817.
    • (1994) Cell , vol.77 , pp. 817
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 29
    • 0028018106 scopus 로고
    • Bcl-2 protects from oxidative damage and apoptotic cell death without interfering with activation of NF-kappa B by TNF
    • ALBRECHT H., TSCHOPP J. & JONGENEEL C.V. (1994) Bcl-2 protects from oxidative damage and apoptotic cell death without interfering with activation of NF-kappa B by TNF. FEBS Lett351, 45.
    • (1994) FEBS Lett , vol.351 , pp. 45
    • Albrecht, H.1    Tschopp, J.2    Jongeneel, C.V.3
  • 30
    • 0029873387 scopus 로고    scopus 로고
    • Reactive oxygen species and programmed cell death
    • JACOBSON M.D. (1996) Reactive oxygen species and programmed cell death. TIBS 21, 83.
    • (1996) TIBS , vol.21 , pp. 83
    • Jacobson, M.D.1
  • 31
    • 0026662445 scopus 로고
    • Inhibition of Superoxide production in B lymphocytes by rac antisense oligonucleotides
    • DORSEUIL O., VAZQUEZ A., LANG P., BERTOGLIO J., GACON G. & LECA G. (1992) Inhibition of Superoxide production in B lymphocytes by rac antisense oligonucleotides. J Biol Chem 267, 20540.
    • (1992) J Biol Chem , vol.267 , pp. 20540
    • Dorseuil, O.1    Vazquez, A.2    Lang, P.3    Bertoglio, J.4    Gacon, G.5    Leca, G.6
  • 32
  • 33
    • 0027067903 scopus 로고
    • Purification and characterisation of Rac2. A cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase
    • KNAUS U.G., HEYWORTH P.G., KINSELLA B.T., CURNUTTE J.T. & BOKOCH G.M. (1992) Purification and characterisation of Rac2. A cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase. J Biol Chem 267, 23575.
    • (1992) J Biol Chem , vol.267 , pp. 23575
    • Knaus, U.G.1    Heyworth, P.G.2    Kinsella, B.T.3    Curnutte, J.T.4    Bokoch, G.M.5
  • 34
    • 0347537940 scopus 로고    scopus 로고
    • Requirement for ceramide initiated SAPK/JNK signalling in stress induced apoptosis
    • VERHEIJ M., BOSE R., LIN X.H. et al. (1996) Requirement for ceramide initiated SAPK/JNK signalling in stress induced apoptosis. Nature 380, 75.
    • (1996) Nature , vol.380 , pp. 75
    • Verheij, M.1    Bose, R.2    Lin, X.H.3
  • 35
    • 0027340426 scopus 로고
    • Fragmentation of DNA in P388D1 macrophages exposed to oxidised low density lipoprotein
    • REID V.C., HARDWICK S.J. & MITCHINSON M.J. (1993) Fragmentation of DNA in P388D1 macrophages exposed to oxidised low density lipoprotein. FEBS Lett 332, 218.
    • (1993) FEBS Lett , vol.332 , pp. 218
    • Reid, V.C.1    Hardwick, S.J.2    Mitchinson, M.J.3
  • 36
    • 0023157655 scopus 로고
    • Clastogenic action of hydroperoxy-5(8 (11), 13-icosatetraenoic acids on the mouse embryo fibroblasts C3H/10T1/2
    • OCHI T. & CERUTTI P.A. (1987) Clastogenic action of hydroperoxy-5(8 (11), 13-icosatetraenoic acids on the mouse embryo fibroblasts C3H/10T1/2. Proc Natl Acad Sci USA 84, 990.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 990
    • Ochi, T.1    Cerutti, P.A.2
  • 37
    • 0028096212 scopus 로고
    • Lipid hydroperoxides induce apoptosis in T-cells displaying a HIV associated gluthatione peroxidase deficiency
    • SANDSTROM P.A., TEBBEY P.W., VAN CLEAVE S. & BUTTKE T.M. (1994) Lipid hydroperoxides induce apoptosis in T-cells displaying a HIV associated gluthatione peroxidase deficiency. J Biol Chem 296, 798.
    • (1994) J Biol Chem , vol.296 , pp. 798
    • Sandstrom, P.A.1    Tebbey, P.W.2    Van Cleave, S.3    Buttke, T.M.4
  • 38
    • 0027199115 scopus 로고
    • Reactive oxygen intermediates activate NFκB in a tyrosine kinase dependent mechanism and in combination with vanadate activate the p56lck and p59fyn tyrosine kinase in human lymphocytes
    • SCHIEVEN G.L., KIRIKARA J.M., MYERS D.E., LEDBETTER J.A. & UCKUN F.M. (1993) Reactive oxygen intermediates activate NFκB in a tyrosine kinase dependent mechanism and in combination with vanadate activate the p56lck and p59fyn tyrosine kinase in human lymphocytes. Blood 82, 1212.
    • (1993) Blood , vol.82 , pp. 1212
    • Schieven, G.L.1    Kirikara, J.M.2    Myers, D.E.3    Ledbetter, J.A.4    Uckun, F.M.5
  • 39
    • 0027974133 scopus 로고
    • Assessing oxygen radicals as mediators in activation of inducible eukaryotic transcription factor NF-κB
    • SCHRECK R. & BAEUERLE P.A. (1994) Assessing oxygen radicals as mediators in activation of inducible eukaryotic transcription factor NF-κB. Methods Enzymol 234, 151.
    • (1994) Methods Enzymol , vol.234 , pp. 151
    • Schreck, R.1    Baeuerle, P.A.2
  • 40
    • 0027176524 scopus 로고
    • Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B
    • HENKEL T., MACHLEIDT T., ALKALAY I., KRÖNKE M., BEN NERIAH Y. & BAEUERLE P. (1993) Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B. Nature 365, 182.
    • (1993) Nature , vol.365 , pp. 182
    • Henkel, T.1    Machleidt, T.2    Alkalay, I.3    Krönke, M.4    Ben Neriah, Y.5    Baeuerle, P.6
  • 41
    • 0025739254 scopus 로고
    • Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1
    • SCHRECK R., REIBER P. & BAEUERLE P.A. (1991) Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J 10, 2247.
    • (1991) EMBO J , vol.10 , pp. 2247
    • Schreck, R.1    Reiber, P.2    Baeuerle, P.A.3
  • 42
    • 0026517239 scopus 로고
    • Molecular cloning of the interleukin I converting enzyme
    • CERRETTI D.P., KOZLOVSKY C.J., MOSLEY B. et al. (1992) Molecular cloning of the interleukin I converting enzyme. Science 256, 97.
    • (1992) Science , vol.256 , pp. 97
    • Cerretti, D.P.1    Kozlovsky, C.J.2    Mosley, B.3
  • 43
    • 0026507126 scopus 로고
    • A novel heterodimeric cysteine protease is required for interleukin-I beta processing in monocytes
    • THORNBERRY N.A., BULL H.G., CALAYCAY J.R. et al. (1992) A novel heterodimeric cysteine protease is required for interleukin-I beta processing in monocytes. Nature 356, 768.
    • (1992) Nature , vol.356 , pp. 768
    • Thornberry, N.A.1    Bull, H.G.2    Calaycay, J.R.3
  • 44
    • 0027449187 scopus 로고
    • Induction of apoptosis in fibroblasts by IL-1-beta converting enzyme, a mammalian homolog of the C. elegans cell death gene ced 3
    • MIURA M., ZHU H., ROTELLO R., HARTWIG E.A. & YUAN J. (1993) Induction of apoptosis in fibroblasts by IL-1-beta converting enzyme, a mammalian homolog of the C. elegans cell death gene ced 3. Cell 75, 653.
    • (1993) Cell , vol.75 , pp. 653
    • Miura, M.1    Zhu, H.2    Rotello, R.3    Hartwig, E.A.4    Yuan, J.5
  • 45
    • 0028168593 scopus 로고
    • Ich-1. an Ice/ced-3 related gene, encodes both positive and negative regulators of programmed cell death
    • WANG I., MIURA M., BERGERON L., ZHU H. & YUAN J. (1994) Ich-1. an Ice/ced-3 related gene, encodes both positive and negative regulators of programmed cell death. Cell 78, 739.
    • (1994) Cell , vol.78 , pp. 739
    • Wang, I.1    Miura, M.2    Bergeron, L.3    Zhu, H.4    Yuan, J.5
  • 46
    • 0028920863 scopus 로고
    • Altered cytokine and apoptosis in mice deficient for interleukin-I beta converting enzyme
    • KUIDA K., LIPPKE J.A., KU G. et al (1995) Altered cytokine and apoptosis in mice deficient for interleukin-I beta converting enzyme. Science 267, 2000.
    • (1995) Science , vol.267 , pp. 2000
    • Kuida, K.1    Lippke, J.A.2    Ku, G.3
  • 47
    • 0026588374 scopus 로고
    • N- (2-mercapthoethyl)-1. 3-propane-diamine (WR-1065) protects thymocytes from programmed cell death
    • RAMAKRISHNAN N. & CATRAVAS G. (1992) N- (2-mercapthoethyl)-1. 3-propane-diamine (WR-1065) protects thymocytes from programmed cell death. J Immunol 148, 1817.
    • (1992) J Immunol , vol.148 , pp. 1817
    • Ramakrishnan, N.1    Catravas, G.2
  • 48
    • 0028169881 scopus 로고
    • N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro
    • MAYER M. & NOBLE M. (1994) N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro. Proc Natl Acad Sci USA 91, 7496.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7496
    • Mayer, M.1    Noble, M.2
  • 49
    • 0025887488 scopus 로고
    • Protective activity of adult T cell leukemia-derived factor (ADF) against tumor necrosis factor
    • MATSUDA M., MASUTANI H., NAKAMURA H. et al. (1991) Protective activity of adult T cell leukemia-derived factor (ADF) against tumor necrosis factor. J Immunol 147, 3837.
    • (1991) J Immunol , vol.147 , pp. 3837
    • Matsuda, M.1    Masutani, H.2    Nakamura, H.3
  • 50
    • 0027394553 scopus 로고
    • Overexpression of mitochondrial manganese Superoxide dismutase promotes the survival of tumor cells exposed to interleukin-1. tumor necrosis factor, selected anticancer drugs, and ionizing radiation
    • HIROSE K., BONGO D.L., OPPENHEIM J.J. & MATSUSHIMA K. (1993) Overexpression of mitochondrial manganese Superoxide dismutase promotes the survival of tumor cells exposed to interleukin-1. tumor necrosis factor, selected anticancer drugs, and ionizing radiation. FASEB J 7, 361.
    • (1993) FASEB J , vol.7 , pp. 361
    • Hirose, K.1    Bongo, D.L.2    Oppenheim, J.J.3    Matsushima, K.4
  • 51
    • 0027161158 scopus 로고
    • Effect of Bcl-2 on Fas antigen mediated cell death
    • ITOH N., TSUJIMOTO Y. & NAGATA S. (1993) Effect of Bcl-2 on Fas antigen mediated cell death J Immunol 151, 621.
    • (1993) J Immunol , vol.151 , pp. 621
    • Itoh, N.1    Tsujimoto, Y.2    Nagata, S.3
  • 52
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2 binding protein with anti-cell death activity
    • TAKAYAMA S., SATO T., KRAJEWSKI S. et al. (1995) Cloning and functional analysis of BAG-1: a novel Bcl-2 binding protein with anti-cell death activity. Cell 80, 279.
    • (1995) Cell , vol.80 , pp. 279
    • Takayama, S.1    Sato, T.2    Krajewski, S.3
  • 53
    • 0029946043 scopus 로고    scopus 로고
    • Fas mediates apoptosis in human monocytes by a reactive oxygen intermediate dependent pathway
    • UM H.D., ORENSTEIN J.M. & WAL S.M. (1996) Fas mediates apoptosis in human monocytes by a reactive oxygen intermediate dependent pathway. J Immunol 156, 3469.
    • (1996) J Immunol , vol.156 , pp. 3469
    • Um, H.D.1    Orenstein, J.M.2    Wal, S.M.3
  • 54
    • 0030012411 scopus 로고    scopus 로고
    • Fas-mediated apoptosis is modulated by intracellular glutathione in human T cells
    • CHIBA T., TAKAHASHI S., SATO N., ISHIJ S. & KIKUCHI K. (1996) Fas-mediated apoptosis is modulated by intracellular glutathione in human T cells. Eur J Immunol 26, 1164.
    • (1996) Eur J Immunol , vol.26 , pp. 1164
    • Chiba, T.1    Takahashi, S.2    Sato, N.3    Ishij, S.4    Kikuchi, K.5
  • 55
    • 0028001530 scopus 로고
    • Divergent signalling via Apo-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death
    • SCHULTZE-OSTHOFF K., KRAMMER P.H. & DRÖGE W. (1994) Divergent signalling via Apo-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death. EMBO J 13, 4587.
    • (1994) EMBO J , vol.13 , pp. 4587
    • Schultze-Osthoff, K.1    Krammer, P.H.2    Dröge, W.3
  • 56
    • 0027401203 scopus 로고
    • Mutations in the Cu/Zn superoxid dismutase gene are associated with familial amyotrophic sclerosis
    • ROSEN D.R., SIDDIQUE T., PATTERSON D. et al. (1993) Mutations in the Cu/Zn superoxid dismutase gene are associated with familial amyotrophic sclerosis. Nature 362, 59.
    • (1993) Nature , vol.362 , pp. 59
    • Rosen, D.R.1    Siddique, T.2    Patterson, D.3
  • 58
    • 0028939139 scopus 로고
    • Programmed cell death and Bcl-2 protection in very low oxygen
    • JACOBSON M.D. & RAFF M.C. (1995) Programmed cell death and Bcl-2 protection in very low oxygen. Nature 374, 814.
    • (1995) Nature , vol.374 , pp. 814
    • Jacobson, M.D.1    Raff, M.C.2
  • 59
    • 0029022365 scopus 로고
    • Involvement of an ICE-like protease in Fas mediated apoptosis
    • ENARI M., HUG H. & NAGATA S. (1995) Involvement of an ICE-like protease in Fas mediated apoptosis. Nature 375, 78.
    • (1995) Nature , vol.375 , pp. 78
    • Enari, M.1    Hug, H.2    Nagata, S.3
  • 60
    • 0029005805 scopus 로고
    • Requirement of an ICE Ced-3 protease for Fas/Apo-1 mediated apoptosis
    • LOS M., DE CRAEN M.V., PENNING, L.C. et al. (1995) Requirement of an ICE Ced-3 protease for Fas/Apo-1 mediated apoptosis. Nature 375, 81.
    • (1995) Nature , vol.375 , pp. 81
    • Los, M.1    De Craen, M.V.2    Penning, L.C.3
  • 61
    • 0028984948 scopus 로고
    • Mice deficient in IL-1 beta converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
    • LI P., ALLEN H., BANERJEI S., FRANKLIN S. et al. (1995) Mice deficient in IL-1 beta converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell 80, 401.
    • (1995) Cell , vol.80 , pp. 401
    • Li, P.1    Allen, H.2    Banerjei, S.3    Franklin, S.4
  • 62
    • 0027732538 scopus 로고
    • Proteins regulating Ras and its relatives
    • BOGUSKI M.S. & MCCORMICK F. (1993) Proteins regulating Ras and its relatives. Nature 366, 643.
    • (1993) Nature , vol.366 , pp. 643
    • Boguski, M.S.1    Mccormick, F.2
  • 63
    • 0026642195 scopus 로고
    • Induction of apoptosis in fibroblasts by c-myc protein
    • EVAN G.I., WYLLIE A.H., GILBERT C.S., LITTLEWOOD T.D. et al. (1992) Induction of apoptosis in fibroblasts by c-myc protein. Cell 69, 119.
    • (1992) Cell , vol.69 , pp. 119
    • Evan, G.I.1    Wyllie, A.H.2    Gilbert, C.S.3    Littlewood, T.D.4
  • 65
    • 0026645859 scopus 로고
    • Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines
    • COLOTTA F., POLENTARUTTI N., SIRONI M. & MANTOVANI A. (1992) Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines. J Biol Chem 267, 18278.
    • (1992) J Biol Chem , vol.267 , pp. 18278
    • Colotta, F.1    Polentarutti, N.2    Sironi, M.3    Mantovani, A.4
  • 67
    • 0023635251 scopus 로고
    • Rodent fibroblast tumours expressing human myc and ras genes: Growth, metastasis and endogenous oncogene expression
    • WYLLIE A., ROSE K.A., MORRIS R.G., STEEL C.M., FOSTER E. & SPANDIDOS D.A. (1987) Rodent fibroblast tumours expressing human myc and ras genes: growth, metastasis and endogenous oncogene expression. Br J Cancer 56, 251.
    • (1987) Br J Cancer , vol.56 , pp. 251
    • Wyllie, A.1    Rose, K.A.2    Morris, R.G.3    Steel, C.M.4    Foster, E.5    Spandidos, D.A.6
  • 68
    • 0029029743 scopus 로고
    • R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism
    • WANG H.G., MILLAN J.A., COX A.D. et al. (1995) R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism. J Cell Biology 129, 1103.
    • (1995) J Cell Biology , vol.129 , pp. 1103
    • Wang, H.G.1    Millan, J.A.2    Cox, A.D.3
  • 69
    • 0028276685 scopus 로고
    • Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF 1
    • TANAKA N., ISHIHARA M., KIIAGAWA M. et al. (1994) Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF 1. Cell 77, 829.
    • (1994) Cell , vol.77 , pp. 829
    • Tanaka, N.1    Ishihara, M.2    Kiiagawa, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.