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Volumn 15, Issue 1, 2007, Pages 14-21

Cyclooxygenase II: A molecular target for colorectal cancer prevention and treatment?

Author keywords

Chemoprevention; Colorectal cancer; COX 2 inhibitor; Cyclooxygenase 2 (COX 2); Microsomal prostaglandin E synthase 1 (mPGES 1)

Indexed keywords


EID: 76349106890     PISSN: 13446835     EISSN: None     Source Type: Journal    
DOI: 10.4993/acrt.15.14     Document Type: Review
Times cited : (2)

References (102)
  • 1
    • 0025998557 scopus 로고
    • Aspirin use and reduced risk of fatal colon cancer
    • Thun, M.J., Namboodiri, M.M., Heath, C.W. Jr. (1991) Aspirin use and reduced risk of fatal colon cancer. N. Engl. J. Med. 325: 1593-1596.
    • (1991) N. Engl. J. Med , vol.325 , pp. 1593-1596
    • Thun, M.J.1    Namboodiri, M.M.2    Heath Jr., C.W.3
  • 5
    • 0021050635 scopus 로고
    • Inhibition of initiation and promotion by N-methylnitrosourea-induced colon carcinogenesis in rats by non-steroid anti-inflammatory agent indomethacin
    • Narisawa, T., Satoh, M., Sano, M., Takahashi, T. (1983) Inhibition of initiation and promotion by N-methylnitrosourea-induced colon carcinogenesis in rats by non-steroid anti-inflammatory agent indomethacin. Carcinogenesis. 4: 1225-1227.
    • (1983) Carcinogenesis , vol.4 , pp. 1225-1227
    • Narisawa, T.1    Satoh, M.2    Sano, M.3    Takahashi, T.4
  • 6
    • 0023162551 scopus 로고
    • Involvement of prostaglandin E2 in bile acid-caused promotion of colon carcinogenesis and anti-promotion by the cyclooxygenase inhibitor indomethacin
    • Narisawa, T., Takahashi, M., Niwa, M., Fukaura, Y., Wakizaka, A. (1987) Involvement of prostaglandin E2 in bile acid-caused promotion of colon carcinogenesis and anti-promotion by the cyclooxygenase inhibitor indomethacin. Jpn. J. Cancer. Res. 78: 791-798.
    • (1987) Jpn. J. Cancer. Res , vol.78 , pp. 791-798
    • Narisawa, T.1    Takahashi, M.2    Niwa, M.3    Fukaura, Y.4    Wakizaka, A.5
  • 7
    • 0025850280 scopus 로고
    • Investigation of colonic prostaglandins in carcinogenesis in the rat colon
    • Yamaguchi, A., Ishida, T., Nishimura, G., Katoh, M., Miyazaki, I. (1991) Investigation of colonic prostaglandins in carcinogenesis in the rat colon. Dis. Colon. Rectum. 34: 572-576.
    • (1991) Dis. Colon. Rectum , vol.34 , pp. 572-576
    • Yamaguchi, A.1    Ishida, T.2    Nishimura, G.3    Katoh, M.4    Miyazaki, I.5
  • 8
    • 0030894288 scopus 로고    scopus 로고
    • Prostaglandin H synthases, nonsteroidal anti-inflammatory drugs, and colon cancer
    • Levy GN. (1997) Prostaglandin H synthases, nonsteroidal anti-inflammatory drugs, and colon cancer. FASEB. J. 11: 234-247.
    • (1997) FASEB. J , vol.11 , pp. 234-247
    • Levy, G.N.1
  • 10
    • 0018868971 scopus 로고
    • Prostaglandin in human breast cancer: Evidence suggesting that an elevated prostaglandin production is a marker of high metastatic potential for neoplastic cells
    • Rolland, P.H., Martin, P.M., Jacquemier, J., Rolland, A.M., Toga, M. (1980) Prostaglandin in human breast cancer: Evidence suggesting that an elevated prostaglandin production is a marker of high metastatic potential for neoplastic cells. J. Natl. Cancer. Inst. 64: 1061-1070.
    • (1980) J. Natl. Cancer. Inst , vol.64 , pp. 1061-1070
    • Rolland, P.H.1    Martin, P.M.2    Jacquemier, J.3    Rolland, A.M.4    Toga, M.5
  • 13
    • 0032521401 scopus 로고    scopus 로고
    • Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: Up-regulation of interleukin-10 and down-regulation of interleukin-12 production
    • Huang, M., Stolina, M., Sharma, S., Mao, J., Zhu, L., Miller, P., Wollman, J., Herschman, H., Dubinett, S. (1998) Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: Up-regulation of interleukin-10 and down-regulation of interleukin-12 production. Cancer. Res. 58: 1208-1216.
    • (1998) Cancer. Res , vol.58 , pp. 1208-1216
    • Huang, M.1    Stolina, M.2    Sharma, S.3    Mao, J.4    Zhu, L.5    Miller, P.6    Wollman, J.7    Herschman, H.8    Dubinett, S.9
  • 20
    • 0035461344 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in an adenoid cystic carcinoma of the uterine cervix
    • Ishiko, O., Sumi, T., Yoshida, H., Tokuyama, O., Wakasa, K., Haba, T., Ogita, S. (2001) Cyclooxygenase-2 expression in an adenoid cystic carcinoma of the uterine cervix. Oncol. Rep. 8: 1023-1025.
    • (2001) Oncol. Rep , vol.8 , pp. 1023-1025
    • Ishiko, O.1    Sumi, T.2    Yoshida, H.3    Tokuyama, O.4    Wakasa, K.5    Haba, T.6    Ogita, S.7
  • 21
    • 0035008948 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression and prostaglandin E2 synthesis are up-regulated in carcinomas of the cervix: A possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors
    • Sales, K.J., Katz, A.A., Davis, M., Hinz, S., Soeters, R.P., Hofmeyr, M.D., Millar, R.P., Jabbour, H.N. (2001) Cyclooxygenase-2 expression and prostaglandin E2 synthesis are up-regulated in carcinomas of the cervix: A possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors. J. Clin. Endocrinol. Metab. 86: 2243-2249.
    • (2001) J. Clin. Endocrinol. Metab , vol.86 , pp. 2243-2249
    • Sales, K.J.1    Katz, A.A.2    Davis, M.3    Hinz, S.4    Soeters, R.P.5    Hofmeyr, M.D.6    Millar, R.P.7    Jabbour, H.N.8
  • 23
    • 0023270948 scopus 로고
    • Dose-related inhibition of colon carcinogenesis by dietary piroxicam, a nonsteroidal anti-inflammatory drug, during different stages of rat colon tumor development
    • Reddy, B.S., Maruyama, H., Kelloff, G. (1987) Dose-related inhibition of colon carcinogenesis by dietary piroxicam, a nonsteroidal anti-inflammatory drug, during different stages of rat colon tumor development. Cancer. Res. 47: 5340-5346.
    • (1987) Cancer. Res , vol.47 , pp. 5340-5346
    • Reddy, B.S.1    Maruyama, H.2    Kelloff, G.3
  • 25
    • 0021042042 scopus 로고
    • Inhibition of mammary carcinogenesis by flurbiprofen, a non-steroidal anti-inflammatory agent
    • McCormic, D.L., Moon, R.C. (1983) Inhibition of mammary carcinogenesis by flurbiprofen, a non-steroidal anti-inflammatory agent. Br. J. Cancer. 48: 859-861.
    • (1983) Br. J. Cancer , vol.48 , pp. 859-861
    • McCormic, D.L.1    Moon, R.C.2
  • 26
    • 0021796079 scopus 로고
    • Modulation of rat mammary carcinogenesis by indomethacin
    • McCormic, D.L., Madigan, M.J., Moon, R.C. (1985) Modulation of rat mammary carcinogenesis by indomethacin. Cancer. Res. 45: 1803-1808.
    • (1985) Cancer. Res , vol.45 , pp. 1803-1808
    • McCormic, D.L.1    Madigan, M.J.2    Moon, R.C.3
  • 28
    • 0031408201 scopus 로고    scopus 로고
    • Inhibition of lung tumorigenesis by sulindac: Comparison of two experimental protocols
    • Castonguay, A., Rioux, N. (1997) Inhibition of lung tumorigenesis by sulindac: Comparison of two experimental protocols. Carcinogenesis, 18: 491-496,
    • (1997) Carcinogenesis , vol.18 , pp. 491-496
    • Castonguay, A.1    Rioux, N.2
  • 29
    • 0026036550 scopus 로고
    • Prostacyclin and prostaglandin E1: Molecular mechanisms and therapeutic utility
    • Kerins, D.M., Murray, R., FitzGerald, G.A. (1991) Prostacyclin and prostaglandin E1: molecular mechanisms and therapeutic utility. Prog. Hemost. Thromb. 10: 307-337.
    • (1991) Prog. Hemost. Thromb , vol.10 , pp. 307-337
    • Kerins, D.M.1    Murray, R.2    FitzGerald, G.A.3
  • 30
    • 0025909387 scopus 로고
    • Human platelet/ erythroleukemia cell prostaglandin G/H synthase: DNA cloning, expression, and gene chromosomal assignment
    • Funk, C.D., Funk, L.B., Kennedy, M.E., Pong, A.S., Fitzgerald, G.A. (1991) Human platelet/ erythroleukemia cell prostaglandin G/H synthase: DNA cloning, expression, and gene chromosomal assignment. FASEB. J. 5: 2304-2312.
    • (1991) FASEB. J , vol.5 , pp. 2304-2312
    • Funk, C.D.1    Funk, L.B.2    Kennedy, M.E.3    Pong, A.S.4    Fitzgerald, G.A.5
  • 33
    • 0030049390 scopus 로고    scopus 로고
    • Prostaglandin synthase 2
    • Herschman, H.R. (1996) Prostaglandin synthase 2. Biochem. Biophys. Acta. 1299: 125-140.
    • (1996) Biochem. Biophys. Acta , vol.1299 , pp. 125-140
    • Herschman, H.R.1
  • 34
    • 0028824312 scopus 로고
    • Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element
    • Inoue, H., Yokoyama, C., Hara, S., Tone, Y., Tanabe, T. (1995) Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element. J. Biol. Chem. 270: 24965-24971.
    • (1995) J. Biol. Chem , vol.270 , pp. 24965-24971
    • Inoue, H.1    Yokoyama, C.2    Hara, S.3    Tone, Y.4    Tanabe, T.5
  • 35
    • 0037166271 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: Evidence for involvement of AP-1 and PEA3
    • Subbaramaiah, K., Norton, L., Gerald, W., Dannenberg, A.J. (2002) Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3. J. Biol. Chem. 277:18649-18657.
    • (2002) J. Biol. Chem , vol.277 , pp. 18649-18657
    • Subbaramaiah, K.1    Norton, L.2    Gerald, W.3    Dannenberg, A.J.4
  • 37
    • 0027371123 scopus 로고
    • Altered eicosanoid levels in human colon cancer
    • Rigas, B., Goldman, I.S., Levine, L. (1993) Altered eicosanoid levels in human colon cancer. J. Lab, Clin. Med. 122: 518-523.
    • (1993) J. Lab, Clin. Med , vol.122 , pp. 518-523
    • Rigas, B.1    Goldman, I.S.2    Levine, L.3
  • 39
    • 0034692689 scopus 로고    scopus 로고
    • Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandinE2 synthase that acts in concert with cyclooxygenase-2
    • Murakami, M., Naraba, H., Tanioka, T., Semmyo, N., Nakatani, Y., Kojima, F., Ikeda, T., Fueki, M., Ueno, A., Oh, S., Kudo, I. (2000) Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandinE2 synthase that acts in concert with cyclooxygenase-2. J. Biol. Chem. 275: 32783-32792.
    • (2000) J. Biol. Chem , vol.275 , pp. 32783-32792
    • Murakami, M.1    Naraba, H.2    Tanioka, T.3    Semmyo, N.4    Nakatani, Y.5    Kojima, F.6    Ikeda, T.7    Fueki, M.8    Ueno, A.9    Oh, S.10    Kudo, I.11
  • 40
    • 0033594963 scopus 로고    scopus 로고
    • Jakobsson, P.J., Thoren, S., Morgenstern, R., Samuelsson, B. (1999)Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target Proc. Natl. Acad. Sci. USA. 96: 7220-7225.
    • Jakobsson, P.J., Thoren, S., Morgenstern, R., Samuelsson, B. (1999)Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target Proc. Natl. Acad. Sci. USA. 96: 7220-7225.
  • 41
    • 0034693050 scopus 로고    scopus 로고
    • Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in mediated prostaglandin E2 biosynthesis
    • Tanioka, T., Nakatani, Y., Semmyo, N., Murakami, M., Kudo, I. (2000) Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in mediated prostaglandin E2 biosynthesis. J. Biol. Chem. 275: 32775-32782.
    • (2000) J. Biol. Chem , vol.275 , pp. 32775-32782
    • Tanioka, T.1    Nakatani, Y.2    Semmyo, N.3    Murakami, M.4    Kudo, I.5
  • 45
    • 12144253664 scopus 로고    scopus 로고
    • Expression of proteins related to prostaglandin E2 biosynthesis is increased in human gastric cancer and during gastric carcinogenesis
    • Jang, T.J. (2004) Expression of proteins related to prostaglandin E2 biosynthesis is increased in human gastric cancer and during gastric carcinogenesis. Virchows. Arch. 445: 564-571.
    • (2004) Virchows. Arch , vol.445 , pp. 564-571
    • Jang, T.J.1
  • 46
    • 32244432275 scopus 로고    scopus 로고
    • Microsomal prostaglandin E (2) synthase-1 in breast cancer: A potential target for therapy
    • Mehrotra, S., Morimiya, A., Agarwal, B., Konger, R., Badve, S. (2006) Microsomal prostaglandin E (2) synthase-1 in breast cancer: a potential target for therapy. J Pathol. 208: 356-363.
    • (2006) J Pathol , vol.208 , pp. 356-363
    • Mehrotra, S.1    Morimiya, A.2    Agarwal, B.3    Konger, R.4    Badve, S.5
  • 48
    • 0028803728 scopus 로고    scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpression prostaglandin endoperoxide synthase-2
    • Tsujii, M., DuBois, R.N. (1998) Alterations in cellular adhesion and apoptosis in epithelial cells overexpression prostaglandin endoperoxide synthase-2. Cell. 83: 493-501.
    • (1998) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    DuBois, R.N.2
  • 49
    • 0031984810 scopus 로고    scopus 로고
    • Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells
    • Sheng, H., Shao, J., Morrow, J.D. (1998) Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res. 58: 362-366.
    • (1998) Cancer Res , vol.58 , pp. 362-366
    • Sheng, H.1    Shao, J.2    Morrow, J.D.3
  • 50
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • Tsujii, M., Kawano, S., Tsuji, S., Sawaoka, H., Hori, M., DuBois, R.N. (1998) Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell. 93: 705-716.
    • (1998) Cell , vol.93 , pp. 705-716
    • Tsujii, M.1    Kawano, S.2    Tsuji, S.3    Sawaoka, H.4    Hori, M.5    DuBois, R.N.6
  • 51
    • 0030952695 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
    • Tsujii, M., Kawano, S., DuBois, R.N. (1997) Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc. Natl. Acad. Sci. USA. 94: 3336-3340.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3336-3340
    • Tsujii, M.1    Kawano, S.2    DuBois, R.N.3
  • 52
    • 0021288454 scopus 로고
    • Prostaglandin E2-mediated suppression of cellular immunity in colon cancer patients
    • Baich, C.M., Doghert, P.A., Cloud, G.A. (1984) Prostaglandin E2-mediated suppression of cellular immunity in colon cancer patients. Surgery. 95: 71-77.
    • (1984) Surgery , vol.95 , pp. 71-77
    • Baich, C.M.1    Doghert, P.A.2    Cloud, G.A.3
  • 53
    • 0028920842 scopus 로고
    • Potential involvement of IL-10 in suppressing tumor-associated macrophages. Colon-26 derived prostaglandin E2 inhibits TNF-alpha release via a mechanism involving IL-10
    • Kambayashi, T., Alexander, A.R., Fong, M. (1995) Potential involvement of IL-10 in suppressing tumor-associated macrophages. Colon-26 derived prostaglandin E2 inhibits TNF-alpha release via a mechanism involving IL-10. J. Immunol. 154: 3383-3390.
    • (1995) J. Immunol , vol.154 , pp. 3383-3390
    • Kambayashi, T.1    Alexander, A.R.2    Fong, M.3
  • 54
    • 0031408201 scopus 로고    scopus 로고
    • Inhibition of lung tumorigenesis by sulindac: Comparison of two experimental protocols
    • Castonguay, A., Rioux, N. (1997) Inhibition of lung tumorigenesis by sulindac: Comparison of two experimental protocols. Carcinogenesis. 18: 491-496.
    • (1997) Carcinogenesis , vol.18 , pp. 491-496
    • Castonguay, A.1    Rioux, N.2
  • 56
    • 2542438557 scopus 로고    scopus 로고
    • Elevated prostaglandin EP2 receptor in endometrial adenocarcinoma cells promotes vascular endothelial growth factor expression via cyclic 3′,5′-adenosine monophosphate-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase 1/2 signaling pathways
    • Sales, K.J., Maudsley, S., Jabbour, H.N. (2004) Elevated prostaglandin EP2 receptor in endometrial adenocarcinoma cells promotes vascular endothelial growth factor expression via cyclic 3′,5′-adenosine monophosphate-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase 1/2 signaling pathways. Mol. Endocrinol. 18:1533-1545.
    • (2004) Mol. Endocrinol , vol.18 , pp. 1533-1545
    • Sales, K.J.1    Maudsley, S.2    Jabbour, H.N.3
  • 57
    • 8744250174 scopus 로고    scopus 로고
    • Endothelin-1-induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion
    • Spinella, F., Rosano, L., DiCastro, V., Natali, P.G., Bagnato, A. (2004) Endothelin-1-induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion. J. Biol. Chem. 279: 46700-46705.
    • (2004) J. Biol. Chem , vol.279 , pp. 46700-46705
    • Spinella, F.1    Rosano, L.2    DiCastro, V.3    Natali, P.G.4    Bagnato, A.5
  • 58
    • 0033812743 scopus 로고    scopus 로고
    • Indomethacin-induced apoptosis in esophageal adenocarcinoma cells involves upregulation of Bax and translocation of mitochondrial cytochrome C independent of COX-2 expression
    • Aggarwal, S., Taneja, N., Lin, L., Orringer, M.B., Rehemtulla, A., Beer, D.G. (2000) Indomethacin-induced apoptosis in esophageal adenocarcinoma cells involves upregulation of Bax and translocation of mitochondrial cytochrome C independent of COX-2 expression. Neoplasia. 2: 346-356.
    • (2000) Neoplasia , vol.2 , pp. 346-356
    • Aggarwal, S.1    Taneja, N.2    Lin, L.3    Orringer, M.B.4    Rehemtulla, A.5    Beer, D.G.6
  • 60
    • 0034057928 scopus 로고    scopus 로고
    • The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: Evidence of different mechanisms of action
    • Smith, M.L., Hawcroft, G., Hull, M.A. (2000) The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action. Eur. J. Cancer. 36: 664-674.
    • (2000) Eur. J. Cancer , vol.36 , pp. 664-674
    • Smith, M.L.1    Hawcroft, G.2    Hull, M.A.3
  • 61
    • 0030602860 scopus 로고    scopus 로고
    • Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway
    • Hanif, R., Pittas, A., Feng, Y., Koutsos, M.I., Qiao, L., Staiano-Coico, L., Shiff, S.I., Rigas, B. (1996) Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway. Biochem. Pharmacol. 52: 237-245.
    • (1996) Biochem. Pharmacol , vol.52 , pp. 237-245
    • Hanif, R.1    Pittas, A.2    Feng, Y.3    Koutsos, M.I.4    Qiao, L.5    Staiano-Coico, L.6    Shiff, S.I.7    Rigas, B.8
  • 62
    • 0036531924 scopus 로고    scopus 로고
    • Celecoxib exhibits the greatest potency amongst cyclooxygenase (COX) inhibitors for growth inhibition of COX-2-negative hematopoietic and epithelial cell lines
    • Waskewich, C., Blumenthal, R.D., Li, H., Stein, R., Goldenberg, D.M., Burton, J. (2002) Celecoxib exhibits the greatest potency amongst cyclooxygenase (COX) inhibitors for growth inhibition of COX-2-negative hematopoietic and epithelial cell lines. Cancer. Res. 62: 2029-2033.
    • (2002) Cancer. Res , vol.62 , pp. 2029-2033
    • Waskewich, C.1    Blumenthal, R.D.2    Li, H.3    Stein, R.4    Goldenberg, D.M.5    Burton, J.6
  • 63
    • 0030879456 scopus 로고    scopus 로고
    • Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: Independence from COX-2 protein expression
    • Elder, D.J., Halton, D.E., Hague, A., Paraskeva, C. (1997) Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression. Clin. Cancer. Res. 3: 1679-1683.
    • (1997) Clin. Cancer. Res , vol.3 , pp. 1679-1683
    • Elder, D.J.1    Halton, D.E.2    Hague, A.3    Paraskeva, C.4
  • 64
    • 0035135598 scopus 로고    scopus 로고
    • Growth inhibition and induction of apoptosis in colorectal tumor cells by cyclooxygenase inhibitors
    • Richter, M., Weiss, M., Weinberger, I., Furstenberger, G., Marian, B. (2001) Growth inhibition and induction of apoptosis in colorectal tumor cells by cyclooxygenase inhibitors. Carcinogenesis. 22: 17-25.
    • (2001) Carcinogenesis , vol.22 , pp. 17-25
    • Richter, M.1    Weiss, M.2    Weinberger, I.3    Furstenberger, G.4    Marian, B.5
  • 65
    • 0037123345 scopus 로고    scopus 로고
    • Cyclooxygenase-2, player or spectator in cyclooxygenase-2 inhibitor-induced apoptosis in prostate cancer cells
    • Song, X., Lin, H.P., Johnson, A.J., Tseng, P.H., Yang, Y.T., Kulp, S.K., Chen, C.S. (2002) Cyclooxygenase-2, player or spectator in cyclooxygenase-2 inhibitor-induced apoptosis in prostate cancer cells. J. Natl. Cancer. Inst. 94:585-591.
    • (2002) J. Natl. Cancer. Inst , vol.94 , pp. 585-591
    • Song, X.1    Lin, H.P.2    Johnson, A.J.3    Tseng, P.H.4    Yang, Y.T.5    Kulp, S.K.6    Chen, C.S.7
  • 66
    • 0033575760 scopus 로고    scopus 로고
    • Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts
    • Zhang, X., Morham, S.G., Langenbach, R., Young, D.A. (1999) Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts. J. Exp. Med. 190: 451-459.
    • (1999) J. Exp. Med , vol.190 , pp. 451-459
    • Zhang, X.1    Morham, S.G.2    Langenbach, R.3    Young, D.A.4
  • 67
    • 0034326837 scopus 로고    scopus 로고
    • Celecoxib prevents tumor growth in vivo without toxicity to normal gut: Lack of correlation between in vitro and in vivo models
    • Williams, C.S., Watson, A.J., Sheng, H., Helou, R., Shao, J., DuBois, R.N. (2000) Celecoxib prevents tumor growth in vivo without toxicity to normal gut: lack of correlation between in vitro and in vivo models. Cancer. Res. 60: 6045-6051.
    • (2000) Cancer. Res , vol.60 , pp. 6045-6051
    • Williams, C.S.1    Watson, A.J.2    Sheng, H.3    Helou, R.4    Shao, J.5    DuBois, R.N.6
  • 68
    • 0037055533 scopus 로고    scopus 로고
    • Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer
    • Nagatsuka, I., Yamada, N., Shimizu, S., Ohira, M., Nishino, H., Seki, S., Hirakawa, K. (2002) Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer. Int. J. Cancer. 100: 515-519.
    • (2002) Int. J. Cancer , vol.100 , pp. 515-519
    • Nagatsuka, I.1    Yamada, N.2    Shimizu, S.3    Ohira, M.4    Nishino, H.5    Seki, S.6    Hirakawa, K.7
  • 71
    • 1542359063 scopus 로고    scopus 로고
    • Cyclooxygenase-2 selective inhibition with NS-398 suppresses proliferation and invasiveness and delays liver metastasis in colorectal cancer
    • Yao, M., Lam, E.C., Kelly, C.R., Zhou, W., Wolfe, M.M. (2004) Cyclooxygenase-2 selective inhibition with NS-398 suppresses proliferation and invasiveness and delays liver metastasis in colorectal cancer. Br. J. Cancer. 90: 712-719.
    • (2004) Br. J. Cancer , vol.90 , pp. 712-719
    • Yao, M.1    Lam, E.C.2    Kelly, C.R.3    Zhou, W.4    Wolfe, M.M.5
  • 72
    • 4344689010 scopus 로고    scopus 로고
    • NS-398 inhibits tumor growth and liver metastasis of colon cancer through induction of apoptosis and suppression of the plasminogen activation system in a mouse model
    • Nishikawa, M., Stapleton, P.P., Freeman, T.A., Gaughan, J.P., Matsuda, T., Daly, J.M. (2004) NS-398 inhibits tumor growth and liver metastasis of colon cancer through induction of apoptosis and suppression of the plasminogen activation system in a mouse model. J. Am. Coll. Surg. 199: 428-435.
    • (2004) J. Am. Coll. Surg , vol.199 , pp. 428-435
    • Nishikawa, M.1    Stapleton, P.P.2    Freeman, T.A.3    Gaughan, J.P.4    Matsuda, T.5    Daly, J.M.6
  • 73
    • 0037311125 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice
    • Yao, M., Kargman, S., Lam, E.C., Kelly, C.R., Zheng, Y., Luk, P., Kwong, E., Evans, J.F., Wolfe, M.M. (2003) Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice. Cancer. Res. 63: 586-592.
    • (2003) Cancer. Res , vol.63 , pp. 586-592
    • Yao, M.1    Kargman, S.2    Lam, E.C.3    Kelly, C.R.4    Zheng, Y.5    Luk, P.6    Kwong, E.7    Evans, J.F.8    Wolfe, M.M.9
  • 74
    • 0041323114 scopus 로고    scopus 로고
    • The effect of the selective cyclooxygenase-2 inhibitor rofecoxib on human colorectal cancer liver metastases
    • Fenwick, S.W., Toogood, G.J., Lodge, J.P., Hull, M.A. (2003) The effect of the selective cyclooxygenase-2 inhibitor rofecoxib on human colorectal cancer liver metastases. Gastroenterology. 125: 716-729.
    • (2003) Gastroenterology , vol.125 , pp. 716-729
    • Fenwick, S.W.1    Toogood, G.J.2    Lodge, J.P.3    Hull, M.A.4
  • 75
    • 0035869678 scopus 로고    scopus 로고
    • Tumor invasiveness and liver metastasis of colon cancer cells correlated with cyclooxygenase-2 (COX-2) expression and inhibited by a COX-2-selective inhibitor, etodolac
    • Chen, W.S., Wei, S.J., Liu, J.M., Hsiao, M., Kou-Lin, J., Yang, W.K. (2001) Tumor invasiveness and liver metastasis of colon cancer cells correlated with cyclooxygenase-2 (COX-2) expression and inhibited by a COX-2-selective inhibitor, etodolac. Int. J. Cancer. 91: 894-899.
    • (2001) Int. J. Cancer , vol.91 , pp. 894-899
    • Chen, W.S.1    Wei, S.J.2    Liu, J.M.3    Hsiao, M.4    Kou-Lin, J.5    Yang, W.K.6
  • 76
    • 3543143150 scopus 로고    scopus 로고
    • Combined treatment with selective cyclooxygenase-2 inhibitor and fluorinated pyrimidines for liver metastasis of colon cancer
    • Matsunaga, N., Yamada, N., Ohira, M., Tachimori, A., Nishiguchi, Y., Nishino, H., Seki, S., Hirakawa, K. (2004) Combined treatment with selective cyclooxygenase-2 inhibitor and fluorinated pyrimidines for liver metastasis of colon cancer. Oncol. Rep. 11: 167-171.
    • (2004) Oncol. Rep , vol.11 , pp. 167-171
    • Matsunaga, N.1    Yamada, N.2    Ohira, M.3    Tachimori, A.4    Nishiguchi, Y.5    Nishino, H.6    Seki, S.7    Hirakawa, K.8
  • 77
    • 33644852385 scopus 로고    scopus 로고
    • Etodolac, a selective cyclooxygenase-2 inhibitor, inhibits liver metastasis of colorectal cancer cells via the suppression of MMP-9 activity
    • Ishizaki, T., Katsumata, K., Tsuchida, A., Wada, T., Mori, Y., Hisada, M., Kawakita, H., Aoki, T. (2006) Etodolac, a selective cyclooxygenase-2 inhibitor, inhibits liver metastasis of colorectal cancer cells via the suppression of MMP-9 activity. Int. J. Mol. Med. 17: 357-362.
    • (2006) Int. J. Mol. Med , vol.17 , pp. 357-362
    • Ishizaki, T.1    Katsumata, K.2    Tsuchida, A.3    Wada, T.4    Mori, Y.5    Hisada, M.6    Kawakita, H.7    Aoki, T.8
  • 79
    • 0142250380 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of the effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on rectal polyps in familial adenomatous polyposis patients
    • Higuchi, T., Iwama, T., Yoshinaga, K., Toyooka, M., Taketo, M.M., Sugihara, K. (2003) A randomized, double-blind, placebo-controlled trial of the effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on rectal polyps in familial adenomatous polyposis patients. Clin. Cancer. Res. 9: 4756-4760.
    • (2003) Clin. Cancer. Res , vol.9 , pp. 4756-4760
    • Higuchi, T.1    Iwama, T.2    Yoshinaga, K.3    Toyooka, M.4    Taketo, M.M.5    Sugihara, K.6
  • 80
    • 0036177847 scopus 로고    scopus 로고
    • Long-term treatment with sulindac in familial adenomatous polyposis: A prospective cohort study
    • Cruz-Correa, M., Hylind, L.M., Romans, K.E., Booker, S.V., Giardiello, F.M. (2002) Long-term treatment with sulindac in familial adenomatous polyposis: a prospective cohort study. Gastroenterology. 122: 641-645.
    • (2002) Gastroenterology , vol.122 , pp. 641-645
    • Cruz-Correa, M.1    Hylind, L.M.2    Romans, K.E.3    Booker, S.V.4    Giardiello, F.M.5
  • 81
    • 0028813830 scopus 로고
    • Rectal cancer after prolonged sulindac chemoprevention. A case report
    • Lynch, H.T., Thorson, A.G., Smyrk, T. (1995) Rectal cancer after prolonged sulindac chemoprevention. A case report. Cancer. 75: 936-938.
    • (1995) Cancer , vol.75 , pp. 936-938
    • Lynch, H.T.1    Thorson, A.G.2    Smyrk, T.3
  • 82
    • 0028000576 scopus 로고
    • Adenocarcinoma in the rectal segment in familial polyposis coli is not prevented by sulindac therapy
    • Niv, Y., Fraser, G.M. (1994) Adenocarcinoma in the rectal segment in familial polyposis coli is not prevented by sulindac therapy. Gastroenterology. 107: 854-857.
    • (1994) Gastroenterology , vol.107 , pp. 854-857
    • Niv, Y.1    Fraser, G.M.2
  • 86
    • 33748180713 scopus 로고    scopus 로고
    • Arber, N., Eagle, C.J., Spicak, J., Racz, I., Dite, P., Hajer, J., Zavoral, M., Lechuga, M.J., Gerletti, P., Tang, J., Rosenstein, R.B., Macdonald, K., Bhadra, P., Fowler, R., Wittes, J., Zauber, A.G., Solomon, S.D., Levin, B.; PreSAP Trial Investigators (2006) Celecoxib for the prevention of colorectal adenomatous polyps. N. Engl. J. Med. 3559: 885-95.
    • Arber, N., Eagle, C.J., Spicak, J., Racz, I., Dite, P., Hajer, J., Zavoral, M., Lechuga, M.J., Gerletti, P., Tang, J., Rosenstein, R.B., Macdonald, K., Bhadra, P., Fowler, R., Wittes, J., Zauber, A.G., Solomon, S.D., Levin, B.; PreSAP Trial Investigators (2006) Celecoxib for the prevention of colorectal adenomatous polyps. N. Engl. J. Med. 3559: 885-95.
  • 87
    • 33845288081 scopus 로고    scopus 로고
    • Baron, J.A., Sandler, R.S., Bresalier, R.S., Quan, H., Riddell, R., Lanas, A., Bolognese, J.A., Oxenius, B., Horgan, K., Loftus, S., Morton, D.G.; APPROVe Trial Investigators. (2006) A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas. Gastroenterology. 131: 1674-1682.
    • Baron, J.A., Sandler, R.S., Bresalier, R.S., Quan, H., Riddell, R., Lanas, A., Bolognese, J.A., Oxenius, B., Horgan, K., Loftus, S., Morton, D.G.; APPROVe Trial Investigators. (2006) A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas. Gastroenterology. 131: 1674-1682.
  • 89
    • 0034707105 scopus 로고    scopus 로고
    • Bombardier, C., Laine, L., Reicin, A., Shapiro, D., Burgos-Vargas, R., Davis, B., Day, R., Ferraz, M.B., Hawkey, C.J., Hochberg, M.C., Kvien, T.K., Schnitzer, T.J.; VIGOR Study Group. (2000) Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N. Engl. J. Med. 343: 1520-1528.
    • Bombardier, C., Laine, L., Reicin, A., Shapiro, D., Burgos-Vargas, R., Davis, B., Day, R., Ferraz, M.B., Hawkey, C.J., Hochberg, M.C., Kvien, T.K., Schnitzer, T.J.; VIGOR Study Group. (2000) Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N. Engl. J. Med. 343: 1520-1528.
  • 92
    • 33646415952 scopus 로고    scopus 로고
    • Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function
    • Cheng, Y., Wang, M., Yu, Y., Lawson, J., Funk, C.D., FitzGerald, G.A. Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function. (2006) J. Clin. Invest. 116: 1391-1399.
    • (2006) J. Clin. Invest , vol.116 , pp. 1391-1399
    • Cheng, Y.1    Wang, M.2    Yu, Y.3    Lawson, J.4    Funk, C.D.5    FitzGerald, G.A.6
  • 96
    • 0035947586 scopus 로고    scopus 로고
    • Prostaglandin E2 increases growth and motility of colorectal carcinoma cells
    • Sheng, H., Shao, J., Washington, M.K., DuBois, R.N. (2001) Prostaglandin E2 increases growth and motility of colorectal carcinoma cells. J. Biol. Chem. 276: 18075-18081.
    • (2001) J. Biol. Chem , vol.276 , pp. 18075-18081
    • Sheng, H.1    Shao, J.2    Washington, M.K.3    DuBois, R.N.4
  • 97
    • 0034796261 scopus 로고    scopus 로고
    • Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc (Delta 716) knockout mice
    • Sonoshita, M., Takaku, K., Sasaki, N., Sugimoto, Y., Ushikubi, F., Narumiya, S., Oshima, M., Taketo, M.M. (2001) Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc (Delta 716) knockout mice. Nat. Med. 7: 1048-1051.
    • (2001) Nat. Med , vol.7 , pp. 1048-1051
    • Sonoshita, M.1    Takaku, K.2    Sasaki, N.3    Sugimoto, Y.4    Ushikubi, F.5    Narumiya, S.6    Oshima, M.7    Taketo, M.M.8
  • 98
    • 0037081194 scopus 로고    scopus 로고
    • Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc (Delta716) mouse intestinal polyps
    • Seno, H., Oshima, M., Ishikawa, T.O., Oshima, H., Takaku, K., Chiba, T., Narumiya, S., Taketo, M.M. (2002) Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc (Delta716) mouse intestinal polyps. Cancer. Res. 62:506-511.
    • (2002) Cancer. Res , vol.62 , pp. 506-511
    • Seno, H.1    Oshima, M.2    Ishikawa, T.O.3    Oshima, H.4    Takaku, K.5    Chiba, T.6    Narumiya, S.7    Taketo, M.M.8
  • 101
    • 1842335748 scopus 로고    scopus 로고
    • Tumorigenic transformation of immortalized ECV endothelial cells by cyclooxygenase-1 overexpression
    • Narko, K., Ristimaki, A., MacPhee, M., Smith, E., Haudenschild, C.C., Hla, T. (1997) Tumorigenic transformation of immortalized ECV endothelial cells by cyclooxygenase-1 overexpression. J. Biol. Chem. 272: 21455-21460.
    • (1997) J. Biol. Chem , vol.272 , pp. 21455-21460
    • Narko, K.1    Ristimaki, A.2    MacPhee, M.3    Smith, E.4    Haudenschild, C.C.5    Hla, T.6


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