High seizure frequency prior to antiepileptic treatment is a predictor of pharmacoresistant epilepsy in a rat model of temporal lobe epilepsy

Epilepsia

Volumn 51, Issue 1, 2010, Pages 89-97

  Löscher, Wolfgang ^a   Brandt, Claudia ^b  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b CENTER FOR SYSTEMS NEUROSCIENCE   (Germany)

Author keywords

Antiepileptic drugs; Hippocampal sclerosis; Intractable epilepsy; Phenobarbital

Indexed keywords

PHENOBARBITAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DISEASE SEVERITY; DRUG RESPONSE; EPILEPTIC STATE; FEMALE; NONHUMAN; PREDICTION; PREDICTOR VARIABLE; PRIORITY JOURNAL; RAT; RISK FACTOR; SEIZURE; TEMPORAL LOBE EPILEPSY;

AMYGDALA; ANIMALS; ANTICONVULSANTS; BEHAVIOR, ANIMAL; DIAZEPAM; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; ELECTRIC STIMULATION; ELECTRODES, IMPLANTED; ELECTROENCEPHALOGRAPHY; EPILEPSY, TEMPORAL LOBE; FEMALE; PHENOBARBITAL; PROBABILITY; RATS; RATS, SPRAGUE-DAWLEY; RECURRENCE; SEIZURES; STATUS EPILEPTICUS; VIDEOTAPE RECORDING;

EID: 76249091774     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2009.02183.x     Document Type: Article

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