Multidrug resistance in epilepsy: Rats with drug-resistant seizures exhibit enhanced brain expression of P-glycoprotein compared with rats with drug-responsive seizures

Brain

Volumn 128, Issue 6, 2005, Pages 1358-1368

  Volk, Holger A ^a,b   Löscher, Wolfgang ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b QUEEN MOTHER HOSPITAL FOR ANIMALS   (United Kingdom)

Author keywords

Anti epileptic drugs; Drug resistance; MDR1; Refractory epilepsy

Indexed keywords

ANTICONVULSIVE AGENT; DIAZEPAM; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PHENOBARBITAL;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY; CONTROLLED STUDY; DRUG PENETRATION; ELECTROENCEPHALOGRAM; ELECTROSTIMULATION; ENDOTHELIUM CELL; EPILEPSY; EPILEPTIC STATE; FEMALE; GENE OVEREXPRESSION; IMMUNOHISTOCHEMISTRY; INTRACTABLE EPILEPSY; LIMBIC CORTEX; MAXIMUM TOLERATED DOSE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TEMPORAL LOBE EPILEPSY;

EID: 20444439127     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/awh437     Document Type: Article

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