-
1
-
-
0026508937
-
Prevalence of dementia and probable senile dementia of the Alzheimer type in the Framingham study
-
Bachman DL, Wolf PA, Linn R, Knoefel JE, Cobb J, Belanger A et al (1992) Prevalence of dementia and probable senile dementia of the Alzheimer type in the Framingham study. Neurology 42 : 115 119.
-
(1992)
Neurology
, vol.42
, pp. 115-119
-
-
Bachman, D.L.1
Wolf, P.A.2
Linn, R.3
Knoefel, J.E.4
Cobb, J.5
Belanger, A.6
-
2
-
-
0027457545
-
Incidence of dementia and probable Alzheimer's disease in a general population: The Framingham Study
-
Bachman DL, Wolf PA, Linn RT, Knoefel JE, Cobb JL, Belanger AJ et al (1993) Incidence of dementia and probable Alzheimer's disease in a general population: the Framingham Study. Neurology 43 : 515 519.
-
(1993)
Neurology
, vol.43
, pp. 515-519
-
-
Bachman, D.L.1
Wolf, P.A.2
Linn, R.T.3
Knoefel, J.E.4
Cobb, J.L.5
Belanger, A.J.6
-
3
-
-
0031278270
-
Lack of apolipoprotein e dramatically reduces amyloid β-peptide deposition
-
Bales KR, Verina T, Dodel RC, Du Y, Altstiel L, Bender M et al (1997) Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition. Nat Genet 17 : 263 264.
-
(1997)
Nat Genet
, vol.17
, pp. 263-264
-
-
Bales, K.R.1
Verina, T.2
Dodel, R.C.3
Du, Y.4
Altstiel, L.5
Bender, M.6
-
4
-
-
0033593027
-
Apolipoprotein e is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease
-
Bales KR, Verina T, Cummins DJ, Du Y, Dodel RC, Saura J et al (1999) Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 96 : 15233 15238.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 15233-15238
-
-
Bales, K.R.1
Verina, T.2
Cummins, D.J.3
Du, Y.4
Dodel, R.C.5
Saura, J.6
-
5
-
-
34247506244
-
Transport pathways for clearance of human Alzheimer's amyloid β-peptide and apolipoproteins e and J in the mouse central nervous system
-
Bell RD, Sagare AP, Friedman AE, Bedi GS, Holtzman DM, Deane R, Zlokovic BV (2007) Transport pathways for clearance of human Alzheimer's amyloid β-peptide and apolipoproteins E and J in the mouse central nervous system. J Cereb Blood Flow Metab 27 : 909 918.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 909-918
-
-
Bell, R.D.1
Sagare, A.P.2
Friedman, A.E.3
Bedi, G.S.4
Holtzman, D.M.5
Deane, R.6
Zlokovic, B.V.7
-
6
-
-
14444285507
-
Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: Relation of histologic markers to dementia severity, age, sex, and apolipoprotein e genotype
-
Berg L, McKeel DW Jr., Miller JP, Storandt M, Rubin EH, Morris JC et al (1998) Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype. Arch Neurol 55 : 326 335.
-
(1998)
Arch Neurol
, vol.55
, pp. 326-335
-
-
Berg, L.1
McKeel, Jr.D.W.2
Miller, J.P.3
Storandt, M.4
Rubin, E.H.5
Morris, J.C.6
-
7
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (Berl) 82 : 239 259.
-
(1991)
Acta Neuropathol (Berl)
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
8
-
-
0035102386
-
Augmented senile plaque load in aged female β-amyloid precursor protein-transgenic mice
-
Callahan MJ, Lipinski WJ, Bian F, Durham RA, Pack A, Walker LC (2001) Augmented senile plaque load in aged female β-amyloid precursor protein-transgenic mice. Am J Pathol 158 : 1173 1177.
-
(2001)
Am J Pathol
, vol.158
, pp. 1173-1177
-
-
Callahan, M.J.1
Lipinski, W.J.2
Bian, F.3
Durham, R.A.4
Pack, A.5
Walker, L.C.6
-
9
-
-
75949120522
-
Perivascular drainage of solutes from the brain is modified in the triple transgenic model of Alzheimer's disease: Preliminary findings
-
Carare RO, Lad M, Horsburgh K, Weller RO (2009) Perivascular drainage of solutes from the brain is modified in the triple transgenic model of Alzheimer's disease: preliminary findings. Neuropathol Appl Neurobiol 35 : 2.
-
(2009)
Neuropathol Appl Neurobiol
, vol.35
, pp. 2
-
-
Carare, R.O.1
Lad, M.2
Horsburgh, K.3
Weller, R.O.4
-
10
-
-
0028986408
-
Fibrillogenesis in Alzheimer's disease of amyloid β peptides and apolipoprotein e
-
Castano EM, Prelli F, Wisniewski T, Golabek A, Kumar RA, Soto C, Frangione B (1995) Fibrillogenesis in Alzheimer's disease of amyloid β peptides and apolipoprotein E. Biochem J 306 : 599 604.
-
(1995)
Biochem J
, vol.306
, pp. 599-604
-
-
Castano, E.M.1
Prelli, F.2
Wisniewski, T.3
Golabek, A.4
Kumar, R.A.5
Soto, C.6
Frangione, B.7
-
11
-
-
0038509216
-
APOE ε4 influences the pathological phenotype of Alzheimer's disease by favouring cerebrovascular over parenchymal accumulation of Aβ protein
-
Chalmers K, Wilcock GK, Love S (2003) APOE ε4 influences the pathological phenotype of Alzheimer's disease by favouring cerebrovascular over parenchymal accumulation of Aβ protein. Neuropathol Appl Neurobiol 29 : 231 238.
-
(2003)
Neuropathol Appl Neurobiol
, vol.29
, pp. 231-238
-
-
Chalmers, K.1
Wilcock, G.K.2
Love, S.3
-
12
-
-
16644379264
-
Natural oligomers of the amyloid-β protein specifically disrupt cognitive function
-
Cleary JP, Walsh DM, Hofmeister JJ, Shankar GM, Kuskowski MA, Selkoe DJ, Ashe KH (2005) Natural oligomers of the amyloid-β protein specifically disrupt cognitive function. Nat Neurosci 8 : 79 84.
-
(2005)
Nat Neurosci
, vol.8
, pp. 79-84
-
-
Cleary, J.P.1
Walsh, D.M.2
Hofmeister, J.J.3
Shankar, G.M.4
Kuskowski, M.A.5
Selkoe, D.J.6
Ashe, K.H.7
-
13
-
-
0023762975
-
Clinico-pathologic studies in dementia: Nondemented subjects with pathologically confirmed Alzheimer's disease
-
Crystal H, Dickson D, Fuld P, Masur D, Scott R, Mehler M et al (1988) Clinico-pathologic studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease. Neurology 38 : 1682 1687.
-
(1988)
Neurology
, vol.38
, pp. 1682-1687
-
-
Crystal, H.1
Dickson, D.2
Fuld, P.3
Masur, D.4
Scott, R.5
Mehler, M.6
-
14
-
-
0037200117
-
Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability
-
Dahlgren KN, Manelli AM, Stine WB Jr., Baker LK, Krafft GA, LaDu MJ (2002) Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability. J Biol Chem 277 : 32046 32053.
-
(2002)
J Biol Chem
, vol.277
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Stine, Jr.W.B.3
Baker, L.K.4
Krafft, G.A.5
Ladu, M.J.6
-
15
-
-
0023737806
-
A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: Prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques
-
Davies L, Wolska B, Hilbich C, Multhaup G, Martins R, Simms G et al (1988) A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques. Neurology 38 : 1688 1693.
-
(1988)
Neurology
, vol.38
, pp. 1688-1693
-
-
Davies, L.1
Wolska, B.2
Hilbich, C.3
Multhaup, G.4
Martins, R.5
Simms, G.6
-
16
-
-
57449084208
-
ApoE isoform-specific disruption of amyloid β peptide clearance from mouse brain
-
Deane R, Sagare A, Hamm K, Parisi M, Lane S, Finn MB et al (2008) apoE isoform-specific disruption of amyloid β peptide clearance from mouse brain. J Clin Invest 118 : 4002 4013.
-
(2008)
J Clin Invest
, vol.118
, pp. 4002-4013
-
-
Deane, R.1
Sagare, A.2
Hamm, K.3
Parisi, M.4
Lane, S.5
Finn, M.B.6
-
17
-
-
0036233168
-
Human and murine ApoE markedly alters Aβ metabolism before and after plaque formation in a mouse model of Alzheimer's disease
-
Fagan AM, Watson M, Parsadanian M, Bales KR, Paul SM, Holtzman DM (2002) Human and murine ApoE markedly alters Aβ metabolism before and after plaque formation in a mouse model of Alzheimer's disease. Neurobiol Dis 9 : 305 318.
-
(2002)
Neurobiol Dis
, vol.9
, pp. 305-318
-
-
Fagan, A.M.1
Watson, M.2
Parsadanian, M.3
Bales, K.R.4
Paul, S.M.5
Holtzman, D.M.6
-
18
-
-
39849109811
-
Low-temperature improved-throughput method for analysis of brain fatty acids and assessment of their post-mortem stability
-
Fraser T, Tayler H, Love S (2008) Low-temperature improved-throughput method for analysis of brain fatty acids and assessment of their post-mortem stability. J Neurosci Methods 169 : 135 140.
-
(2008)
J Neurosci Methods
, vol.169
, pp. 135-140
-
-
Fraser, T.1
Tayler, H.2
Love, S.3
-
19
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
-
Games D, Adams D, Alessandrini R, Barbour R, Berthelette P, Blackwell C et al (1995) Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature 373 : 523 527.
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
-
20
-
-
0042838303
-
Alzheimer's disease-affected brain: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss
-
Gong Y, Chang L, Viola KL, Lacor PN, Lambert MP, Finch CE et al (2003) Alzheimer's disease-affected brain: presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss. Proc Natl Acad Sci U S A 100 : 10417 10422.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10417-10422
-
-
Gong, Y.1
Chang, L.2
Viola, K.L.3
Lacor, P.N.4
Lambert, M.P.5
Finch, C.E.6
-
21
-
-
0028991404
-
Apolipoprotein e ε4 and cerebral hemorrhage associated with amyloid angiopathy
-
Greenberg SM, Rebeck GW, Vonsattel JP, Gomez-Isla T, Hyman BT (1995) Apolipoprotein E ε4 and cerebral hemorrhage associated with amyloid angiopathy. Ann Neurol 38 : 254 259.
-
(1995)
Ann Neurol
, vol.38
, pp. 254-259
-
-
Greenberg, S.M.1
Rebeck, G.W.2
Vonsattel, J.P.3
Gomez-Isla, T.4
Hyman, B.T.5
-
22
-
-
0029666065
-
Apolipoprotein e ε4 is associated with the presence and earlier onset of hemorrhage in cerebral amyloid angiopathy
-
Greenberg SM, Briggs ME, Hyman BT, Kokoris GJ, Takis C, Kanter DS et al (1996) Apolipoprotein E ε4 is associated with the presence and earlier onset of hemorrhage in cerebral amyloid angiopathy. Stroke 27 : 1333 1337.
-
(1996)
Stroke
, vol.27
, pp. 1333-1337
-
-
Greenberg, S.M.1
Briggs, M.E.2
Hyman, B.T.3
Kokoris, G.J.4
Takis, C.5
Kanter, D.S.6
-
23
-
-
0033570337
-
Protofibrillar intermediates of amyloid β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
-
Hartley DM, Walsh DM, Ye CP, Diehl T, Vasquez S, Vassilev PM et al (1999) Protofibrillar intermediates of amyloid β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J Neurosci 19 : 8876 8884.
-
(1999)
J Neurosci
, vol.19
, pp. 8876-8884
-
-
Hartley, D.M.1
Walsh, D.M.2
Ye, C.P.3
Diehl, T.4
Vasquez, S.5
Vassilev, P.M.6
-
24
-
-
33947245344
-
Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid β-protein metabolism in mouse models of Alzheimer disease
-
Hemming ML, Selkoe DJ, Farris W (2007) Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid β-protein metabolism in mouse models of Alzheimer disease. Neurobiol Dis 26 : 273 281.
-
(2007)
Neurobiol Dis
, vol.26
, pp. 273-281
-
-
Hemming, M.L.1
Selkoe, D.J.2
Farris, W.3
-
25
-
-
44949210283
-
Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model
-
Hirata-Fukae C, Li HF, Hoe HS, Gray AJ, Minami SS, Hamada K et al (2008) Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model. Brain Res 1216 : 92 103.
-
(2008)
Brain Res
, vol.1216
, pp. 92-103
-
-
Hirata-Fukae, C.1
Li, H.F.2
Hoe, H.S.3
Gray, A.J.4
Minami, S.S.5
Hamada, K.6
-
26
-
-
4243215848
-
Apolipoprotein e isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
-
Holtzman DM, Bales KR, Tenkova T, Fagan AM, Parsadanian M, Sartorius LJ et al (2000) Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 97 : 2892 2897.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 2892-2897
-
-
Holtzman, D.M.1
Bales, K.R.2
Tenkova, T.3
Fagan, A.M.4
Parsadanian, M.5
Sartorius, L.J.6
-
27
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
Hsia AY, Masliah E, McConlogue L, Yu GQ, Tatsuno G, Hu K et al (1999) Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc Natl Acad Sci U S A 96 : 3228 3233.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
McConlogue, L.3
Yu, G.Q.4
Tatsuno, G.5
Hu, K.6
-
28
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S et al (1996) Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice. sci 274 : 99 102.
-
(1996)
Sci
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
-
29
-
-
0033853008
-
Prevalence of AD among whites: A summary by levels of severity
-
Hy LX, Keller DM (2000) Prevalence of AD among whites: a summary by levels of severity. Neurology 55 : 198 204.
-
(2000)
Neurology
, vol.55
, pp. 198-204
-
-
Hy, L.X.1
Keller, D.M.2
-
30
-
-
15944381518
-
Age-related changes of intracellular Aβ in cynomolgus monkey brains
-
Kimura N, Yanagisawa K, Terao K, Ono F, Sakakibara I, Ishii Y et al (2005) Age-related changes of intracellular Aβ in cynomolgus monkey brains. Neuropathol Appl Neurobiol 31 : 170 180.
-
(2005)
Neuropathol Appl Neurobiol
, vol.31
, pp. 170-180
-
-
Kimura, N.1
Yanagisawa, K.2
Terao, K.3
Ono, F.4
Sakakibara, I.5
Ishii, Y.6
-
31
-
-
62649174753
-
Oligomeric amyloid β associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
-
Koffie RM, Meyer-Luehmann M, Hashimoto T, Adams KW, Mielke ML, Garcia-Alloza M et al (2009) Oligomeric amyloid β associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques. Proc Natl Acad Sci U S A 106 : 4012 4017.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 4012-4017
-
-
Koffie, R.M.1
Meyer-Luehmann, M.2
Hashimoto, T.3
Adams, K.W.4
Mielke, M.L.5
Garcia-Alloza, M.6
-
32
-
-
0029671451
-
Water-soluble Aβ (N-40, N-42) oligomers in normal and Alzheimer disease brains
-
Kuo YM, Emmerling MR, Vigo-Pelfrey C, Kasunic TC, Kirkpatrick JB, Murdoch GH et al (1996) Water-soluble Aβ (N-40, N-42) oligomers in normal and Alzheimer disease brains. J Biol Chem 271 : 4077 4081.
-
(1996)
J Biol Chem
, vol.271
, pp. 4077-4081
-
-
Kuo, Y.M.1
Emmerling, M.R.2
Vigo-Pelfrey, C.3
Kasunic, T.C.4
Kirkpatrick, J.B.5
Murdoch, G.H.6
-
33
-
-
33645220400
-
Targeting amyloid-β peptide (Aβ) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Aβ precursor protein (APP) transgenic mice
-
Lee EB, Leng LZ, Zhang B, Kwong L, Trojanowski JQ, Abel T, Lee VM (2006) Targeting amyloid-β peptide (Aβ) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Aβ precursor protein (APP) transgenic mice. J Biol Chem 281 : 4292 4299.
-
(2006)
J Biol Chem
, vol.281
, pp. 4292-4299
-
-
Lee, E.B.1
Leng, L.Z.2
Zhang, B.3
Kwong, L.4
Trojanowski, J.Q.5
Abel, T.6
Lee, V.M.7
-
34
-
-
33645038471
-
A specific amyloid-β protein assembly in the brain impairs memory
-
Lesne S, Koh MT, Kotilinek L, Kayed R, Glabe CG, Yang A et al (2006) A specific amyloid-β protein assembly in the brain impairs memory. Nature 440 : 352 357.
-
(2006)
Nature
, vol.440
, pp. 352-357
-
-
Lesne, S.1
Koh, M.T.2
Kotilinek, L.3
Kayed, R.4
Glabe, C.G.5
Yang, A.6
-
35
-
-
0028603650
-
Incidence of dementia and Alzheimer's disease in elderly community residents of south-western France
-
Letenneur L, Commenges D, Dartigues JF, Barberger-Gateau P (1994) Incidence of dementia and Alzheimer's disease in elderly community residents of south-western France. Int J Epidemiol 23 : 1256 1261.
-
(1994)
Int J Epidemiol
, vol.23
, pp. 1256-1261
-
-
Letenneur, L.1
Commenges, D.2
Dartigues, J.F.3
Barberger-Gateau, P.4
-
37
-
-
0032888131
-
Soluble amyloid β peptide concentration as a predictor of synaptic change in Alzheimer's disease
-
Lue LF, Kuo YM, Roher AE, Brachova L, Shen Y, Sue L et al (1999) Soluble amyloid β peptide concentration as a predictor of synaptic change in Alzheimer's disease. Am J Pathol 155 : 853 862.
-
(1999)
Am J Pathol
, vol.155
, pp. 853-862
-
-
Lue, L.F.1
Kuo, Y.M.2
Roher, A.E.3
Brachova, L.4
Shen, Y.5
Sue, L.6
-
38
-
-
0024503377
-
The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome
-
Mann DM, Esiri MM (1989) The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome. J Neurol Sci 89 : 169 179.
-
(1989)
J Neurol Sci
, vol.89
, pp. 169-179
-
-
Mann, D.M.1
Esiri, M.M.2
-
39
-
-
0000074498
-
The time course of pathological events concerned with plaque formation in Down's syndrome with particular reference to the involvement of microglial cells
-
Mann DM, Younis N, Stoddart RW, Jones D (1992) The time course of pathological events concerned with plaque formation in Down's syndrome with particular reference to the involvement of microglial cells. Neurodegeneration 1 : 201 215.
-
(1992)
Neurodegeneration
, vol.1
, pp. 201-215
-
-
Mann, D.M.1
Younis, N.2
Stoddart, R.W.3
Jones, D.4
-
40
-
-
0032590054
-
Soluble pool of Aβ amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
McLean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K et al (1999) Soluble pool of Aβ amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol 46 : 860 866.
-
(1999)
Ann Neurol
, vol.46
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
-
41
-
-
33749475139
-
Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy
-
Miners JS, Van Helmond Z, Chalmers K, Wilcock G, Love S, Kehoe PG (2006) Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy. J Neuropathol Exp Neurol 65 : 1012 1021.
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 1012-1021
-
-
Miners, J.S.1
Van Helmond, Z.2
Chalmers, K.3
Wilcock, G.4
Love, S.5
Kehoe, P.G.6
-
42
-
-
41149149615
-
Aβ-degrading enzymes in Alzheimer's disease
-
Miners JS, Baig S, Palmer J, Palmer LE, Kehoe PG, Love S (2008) Aβ-degrading enzymes in Alzheimer's disease. Brain Pathol 18 : 240 252.
-
(2008)
Brain Pathol
, vol.18
, pp. 240-252
-
-
Miners, J.S.1
Baig, S.2
Palmer, J.3
Palmer, L.E.4
Kehoe, P.G.5
Love, S.6
-
43
-
-
0024453856
-
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease
-
Morris JC, Heyman A, Mohs RC, Hughes JP, van Belle G, Fillenbaum G et al (1989) The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology 39 : 1159 1165.
-
(1989)
Neurology
, vol.39
, pp. 1159-1165
-
-
Morris, J.C.1
Heyman, A.2
Mohs, R.C.3
Hughes, J.P.4
Van Belle, G.5
Fillenbaum, G.6
-
44
-
-
0034213718
-
High-level neuronal expression of aβ 1-42 in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
-
Mucke L, Masliah E, Yu GQ, Mallory M, Rockenstein EM, Tatsuno G et al (2000) High-level neuronal expression of aβ 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J Neurosci 20 : 4050 4058.
-
(2000)
J Neurosci
, vol.20
, pp. 4050-4058
-
-
Mucke, L.1
Masliah, E.2
Yu, G.Q.3
Mallory, M.4
Rockenstein, E.M.5
Tatsuno, G.6
-
45
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Aβ and synaptic dysfunction
-
Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R et al (2003) Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction. Neuron 39 : 409 421.
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
-
46
-
-
0029666413
-
The apolipoprotein e ε4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant
-
Olichney JM, Hansen LA, Galasko D, Saitoh T, Hofstetter CR, Katzman R, Thal LJ (1996) The apolipoprotein E ε4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant. Neurology 47 : 190 196.
-
(1996)
Neurology
, vol.47
, pp. 190-196
-
-
Olichney, J.M.1
Hansen, L.A.2
Galasko, D.3
Saitoh, T.4
Hofstetter, C.R.5
Katzman, R.6
Thal, L.J.7
-
47
-
-
0029926462
-
Gender difference in apolipoprotein E-associated risk for familial Alzheimer disease: A possible clue to the higher incidence of Alzheimer disease in women
-
Payami H, Zareparsi S, Montee KR, Sexton GJ, Kaye JA, Bird TD et al (1996) Gender difference in apolipoprotein E-associated risk for familial Alzheimer disease: a possible clue to the higher incidence of Alzheimer disease in women. Am J Hum Genet 58 : 803 811.
-
(1996)
Am J Hum Genet
, vol.58
, pp. 803-811
-
-
Payami, H.1
Zareparsi, S.2
Montee, K.R.3
Sexton, G.J.4
Kaye, J.A.5
Bird, T.D.6
-
48
-
-
0031871740
-
Detection of single amyloid β-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy
-
Pitschke M, Prior R, Haupt M, Riesner D (1998) Detection of single amyloid β-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy. Nat Med 4 : 832 834.
-
(1998)
Nat Med
, vol.4
, pp. 832-834
-
-
Pitschke, M.1
Prior, R.2
Haupt, M.3
Riesner, D.4
-
49
-
-
0029665096
-
Apolipoprotein E-ε4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease
-
Premkumar DR, Cohen DL, Hedera P, Friedland RP, Kalaria RN (1996) Apolipoprotein E-ε4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease. Am J Pathol 148 : 2083 2095.
-
(1996)
Am J Pathol
, vol.148
, pp. 2083-2095
-
-
Premkumar, D.R.1
Cohen, D.L.2
Hedera, P.3
Friedland, R.P.4
Kalaria, R.N.5
-
50
-
-
0032989712
-
Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease
-
Price JL, Morris JC (1999) Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease. Ann Neurol 45 : 358 368.
-
(1999)
Ann Neurol
, vol.45
, pp. 358-368
-
-
Price, J.L.1
Morris, J.C.2
-
51
-
-
33645824779
-
Dissociation of neuropathology from severity of dementia in late-onset Alzheimer disease
-
Prohovnik I, Perl DP, Davis KL, Libow L, Lesser G, Haroutunian V (2006) Dissociation of neuropathology from severity of dementia in late-onset Alzheimer disease. Neurology 66 : 49 55.
-
(2006)
Neurology
, vol.66
, pp. 49-55
-
-
Prohovnik, I.1
Perl, D.P.2
Davis, K.L.3
Libow, L.4
Lesser, G.5
Haroutunian, V.6
-
52
-
-
0025273369
-
Prevalence of clinically diagnosed Alzheimer's disease and other dementing disorders: A door-to-door survey in Appignano, Macerata Province, Italy
-
Rocca WA, Bonaiuto S, Lippi A, Luciani P, Turtu F, Cavarzeran F, Amaducci L (1990) Prevalence of clinically diagnosed Alzheimer's disease and other dementing disorders: a door-to-door survey in Appignano, Macerata Province, Italy. Neurology 40 : 626 631.
-
(1990)
Neurology
, vol.40
, pp. 626-631
-
-
Rocca, W.A.1
Bonaiuto, S.2
Lippi, A.3
Luciani, P.4
Turtu, F.5
Cavarzeran, F.6
Amaducci, L.7
-
53
-
-
0028290595
-
The prevalence of dementia in Belgium: A population-based door-to-door survey in a rural community
-
Roelands M, Wostyn P, Dom H, Baro F (1994) The prevalence of dementia in Belgium: a population-based door-to-door survey in a rural community. Neuroepidemiology 13 : 155 161.
-
(1994)
Neuroepidemiology
, vol.13
, pp. 155-161
-
-
Roelands, M.1
Wostyn, P.2
Dom, H.3
Baro, F.4
-
54
-
-
49149124343
-
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I et al (2008) Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med 14 : 837 842.
-
(2008)
Nat Med
, vol.14
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
-
55
-
-
0027404280
-
A population-based study of dementia in 85-year-olds
-
Skoog I, Nilsson L, Palmertz B, Andreasson LA, Svanborg A (1993) A population-based study of dementia in 85-year-olds. N Engl J Med 328 : 153 158.
-
(1993)
N Engl J Med
, vol.328
, pp. 153-158
-
-
Skoog, I.1
Nilsson, L.2
Palmertz, B.3
Andreasson, L.A.4
Svanborg, A.5
-
56
-
-
33645505550
-
Effects of secreted oligomers of amyloid β-protein on hippocampal synaptic plasticity: A potent role for trimers
-
Townsend M, Shankar GM, Mehta T, Walsh DM, Selkoe DJ (2006) Effects of secreted oligomers of amyloid β-protein on hippocampal synaptic plasticity: a potent role for trimers. J Physiol 572 : 477 492.
-
(2006)
J Physiol
, vol.572
, pp. 477-492
-
-
Townsend, M.1
Shankar, G.M.2
Mehta, T.3
Walsh, D.M.4
Selkoe, D.J.5
-
57
-
-
57649171529
-
Characterisation of two antibodies to oligomeric Aβ and their use in ELISAs on human brain tissue homogenates
-
van Helmond Z, Heesom K, Love S (2009) Characterisation of two antibodies to oligomeric Aβ and their use in ELISAs on human brain tissue homogenates. J Neurosci Methods 176 : 206 212.
-
(2009)
J Neurosci Methods
, vol.176
, pp. 206-212
-
-
Van Helmond, Z.1
Heesom, K.2
Love, S.3
-
58
-
-
16244390510
-
Stereologic analysis of hippocampal Alzheimer's disease pathology in the oldest-old: Evidence for sparing of the entorhinal cortex and CA1 field
-
von Gunten A, Kovari E, Rivara CB, Bouras C, Hof PR, Giannakopoulos P (2005) Stereologic analysis of hippocampal Alzheimer's disease pathology in the oldest-old: evidence for sparing of the entorhinal cortex and CA1 field. Exp Neurol 193 : 198 206.
-
(2005)
Exp Neurol
, vol.193
, pp. 198-206
-
-
Von Gunten, A.1
Kovari, E.2
Rivara, C.B.3
Bouras, C.4
Hof, P.R.5
Giannakopoulos, P.6
-
59
-
-
0032837741
-
The levels of soluble versus insoluble brain Aβ distinguish Alzheimer's disease from normal and pathologic aging
-
Wang J, Dickson DW, Trojanowski JQ, Lee VM (1999) The levels of soluble versus insoluble brain Aβ distinguish Alzheimer's disease from normal and pathologic aging. Exp Neurol 158 : 328 337.
-
(1999)
Exp Neurol
, vol.158
, pp. 328-337
-
-
Wang, J.1
Dickson, D.W.2
Trojanowski, J.Q.3
Lee, V.M.4
-
60
-
-
0025801744
-
Apolipoprotein e genotyping by one-stage PCR
-
Wenham PR, Price WH, Blandell G (1991) Apolipoprotein E genotyping by one-stage PCR. Lancet 337 : 1158 1159.
-
(1991)
Lancet
, vol.337
, pp. 1158-1159
-
-
Wenham, P.R.1
Price, W.H.2
Blandell, G.3
-
61
-
-
0036489445
-
The relationship between Aβ and memory in the Tg2576 mouse model of Alzheimer's disease
-
Westerman MA, Cooper-Blacketer D, Mariash A, Kotilinek L, Kawarabayashi T, Younkin LH et al (2002) The relationship between Aβ and memory in the Tg2576 mouse model of Alzheimer's disease. J Neurosci 22 : 1858 1867. (Pubitemid 35386304)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.5
, pp. 1858-1867
-
-
Westerman, M.A.1
Cooper-Blacketer, D.2
Mariash, A.3
Kotilinek, L.4
Kawarabayashi, T.5
Younkin, L.H.6
Carlson, G.A.7
Younkin, S.G.8
Ashe, K.H.9
-
62
-
-
60549107033
-
A specific enzyme-linked immunosorbent assay for measuring β-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease
-
Xia W, Yang T, Shankar G, Smith IM, Shen Y, Walsh DM, Selkoe DJ (2009) A specific enzyme-linked immunosorbent assay for measuring β-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease. Arch Neurol 66 : 190 199.
-
(2009)
Arch Neurol
, vol.66
, pp. 190-199
-
-
Xia, W.1
Yang, T.2
Shankar, G.3
Smith, I.M.4
Shen, Y.5
Walsh, D.M.6
Selkoe, D.J.7
|