메뉴 건너뛰기




Volumn 9, Issue 2, 2010, Pages 107-115

Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; ANGIOGENESIS INHIBITOR; FUMAGILLOL CHLOROACETYLCARBAMATE; LEPTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PLATELET DERIVED GROWTH FACTOR B; RECOMBINANT LEPTIN; THROMBOSPONDIN; VASCULOTROPIN A;

EID: 75849165542     PISSN: 14741776     EISSN: 14741784     Source Type: Journal    
DOI: 10.1038/nrd3055     Document Type: Note
Times cited : (343)

References (136)
  • 1
    • 75949094709 scopus 로고    scopus 로고
    • World Health Organization. Obesity and overweight fact sheet. The World Health Organization website [online]
    • World Health Organization. Obesity and overweight fact sheet. The World Health Organization website [online] http://www.who.int/dietphysicalactivity/ media/ en/gsfs-obesity.pdf. 2009.
    • (2009)
  • 2
    • 34848851922 scopus 로고    scopus 로고
    • Angiogenesis modulates adipogenesis and obesity
    • Cao, Y. Angiogenesis modulates adipogenesis and obesity. J. Clin. Invest. 11 7, 2362-2368 (2007).
    • (2007) J. Clin. Invest. , vol.11 , Issue.7 , pp. 2362-2368
    • Cao, Y.1
  • 3
    • 33750510903 scopus 로고    scopus 로고
    • The obesity pipeline: Current strategies in the development of anti-obesity drugs
    • Cooke, D. & Bloom, S. The obesity pipeline: current strategies in the development of anti-obesity drugs. Nature Rev. Drug Discov. 5, 919-931 (2006).
    • (2006) Nature Rev. Drug Discov. , vol.5 , pp. 919-931
    • Cooke, D.1    Bloom, S.2
  • 4
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman, J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nature Med. 1, 27-31 (1995)
    • (1995) Nature Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 5
    • 42349093844 scopus 로고    scopus 로고
    • Angiogenesis and obesity
    • Lijnen, H. R. Angiogenesis and obesity. Cardiovasc. Res. 78, 286-293 (2008).
    • (2008) Cardiovasc. Res. , vol.78 , pp. 286-293
    • Lijnen, H.R.1
  • 6
    • 0035049240 scopus 로고    scopus 로고
    • Endogenous angiogenesis inhibitors and their therapeutic implications
    • Cao, Y. Endogenous angiogenesis inhibitors and their therapeutic implications. Int. J. Biochem. Cell Biol. 33, 357-369 (2001).
    • (2001) Int. J. Biochem. Cell Biol. , vol.33 , pp. 357-369
    • Cao, Y.1
  • 7
    • 84975525035 scopus 로고
    • Seminars in Medicine of the Beth Israel Hospital, Boston Clinical applications of research on angiogenesis
    • Folkman, J. Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis. N. Engl. J. Med. 333, 1757-1763 (1995).
    • (1995) N. Engl. J. Med. , vol.333 , pp. 1757-1763
    • Folkman, J.1
  • 8
    • 0030576517 scopus 로고    scopus 로고
    • And emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan, D. & Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86, 353-364 (1996).
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Patterns, F.J.2
  • 9
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain, R. K. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307, 58-62 (2005).
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 10
    • 20144379162 scopus 로고    scopus 로고
    • Endogenous inhibitors of angiogenesis
    • Nyberg, P., Xie, L. & Kalluri, R. Endogenous inhibitors of angiogenesis. Cancer Res. 65, 3967-3979 (2005).
    • (2005) Cancer Res , vol.65 , pp. 3967-3979
    • Nyberg, P.1    Xie, L.2    Kalluri, R.3
  • 11
    • 33846148701 scopus 로고    scopus 로고
    • Sorafenib in advanced clear-cell renal-cell carcinoma
    • Escudier, B. et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N. Engl. J. Med. 356, 125-134 (2007).
    • (2007) N. Engl. J. Med. , vol.356 , pp. 125-134
    • Escudier, B.1
  • 12
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz, H. et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N. Engl. J. Med. 350, 2335-2342 (2004).
    • (2004) N. Engl. J. Med. , vol.350 , pp. 2335-2342
    • Hurwitz, H.1
  • 13
    • 43249095919 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • Kerbel, R. S. Tumor angiogenesis. N. Engl. J. Med. 358, 2039-2049 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2039-2049
    • Kerbel, R.S.1
  • 14
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
    • Motzer, R. J. et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N. Engl. J. Med. 356, 115-124 (2007).
    • (2007) N. Engl. J. Med. , vol.356 , pp. 115-124
    • Motzer, R.J.1
  • 16
    • 33749426139 scopus 로고    scopus 로고
    • The price of sight \-ranibizumab, bevacizumab, and the treatment of macular degeneration
    • Steinbrook, R. The price of sight \-ranibizumab, bevacizumab, and the treatment of macular degeneration. N. Engl. J. Med. 355, 1409-1412 (2006).
    • (2006) N. Engl. J. Med. , vol.355 , pp. 1409-1412
    • Steinbrook, R.1
  • 17
    • 0032853603 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and diabetes: The agonist versus antagonist paradox
    • Duh, E. & Aiello, L. P. Vascular endothelial growth factor and diabetes: the agonist versus antagonist paradox. Diabetes 48, 1899-1906 (1999).
    • (1999) Diabetes , vol.48 , pp. 1899-1906
    • Duh, E.1    Aiello, L.P.2
  • 18
    • 30744476478 scopus 로고    scopus 로고
    • Retinal angiogenesis in development and disease
    • Gariano, R. F. & Gardner, T. W. Retinal angiogenesis in development and disease. Nature 438, 960-966 (2005).
    • (2005) Nature , vol.438 , pp. 960-966
    • Gariano, R.F.1    Gardner, T.W.2
  • 19
    • 58749091645 scopus 로고    scopus 로고
    • UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality
    • Feldmann, H. M., Golozoubova, V., Cannon, B. & Nedergaard, J. UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. Cell Metab. 9, 203-209 (2009).
    • (2009) Cell Metab , vol.9 , pp. 203-209
    • Feldmann, H.M.1    Golozoubova, V.2    Cannon, B.3    Nedergaard, J.4
  • 20
    • 58749084500 scopus 로고    scopus 로고
    • Why we should put clothes on mice
    • Lodhi, I. J. & Semenkovich, C. F. Why we should put clothes on mice. Cell Metab. 9, 111-112 (2009).
    • (2009) Cell Metab , vol.9 , pp. 111-112
    • Lodhi, I.J.1    Semenkovich, C.F.2
  • 21
    • 57849153917 scopus 로고    scopus 로고
    • Hypoxia-independent angiogenesis in adipose tissues during cold acclimation
    • Xue, Y. et al. Hypoxia-independent angiogenesis in adipose tissues during cold acclimation. Cell Metab. 9, 99-109 (2009).
    • (2009) Cell Metab , vol.9 , pp. 99-109
    • Xue, Y.1
  • 22
    • 33845299821 scopus 로고    scopus 로고
    • Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells
    • Crossno, J. T. Jr, Majka, S. M., Grazia, T., Gill, R. G. & Klemm, D. J. Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells. J. Clin. Invest. 116, 3220-3228 (2006).
    • (2006) J. Clin. Invest. , vol.116 , pp. 3220-3228
    • Crossno Jr., J.T.1    Majka, S.M.2    Grazia, T.3    Gill, R.G.4    Klemm, D.J.5
  • 23
    • 53549130485 scopus 로고    scopus 로고
    • White fat progenitor cells reside in the adipose vasculature
    • Tang, W. et al. White fat progenitor cells reside in the adipose vasculature. Science 322, 583-586 (2008).
    • (2008) Science , vol.322 , pp. 583-586
    • Tang, W.1
  • 24
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil, G. S. Inflammation and metabolic disorders. Nature 444, 860-867 (2006).
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 25
    • 34249883300 scopus 로고    scopus 로고
    • Obesity: The two faces of fat
    • Powell, K. Obesity: the two faces of fat. Nature 447, 525-527 (2007).
    • (2007) Nature , vol.447 , pp. 525-527
    • Powell, K.1
  • 26
    • 0035933126 scopus 로고    scopus 로고
    • Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF
    • Cao, R., Brakenhielm, E., Wahlestedt, C., Thyberg, J. & Cao, Y. Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF. Proc. Natl Acad. Sci. USA 98, 6390-6395 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 6390-6395
    • Cao, R.1    Brakenhielm, E.2    Wahlestedt, C.3    Thyberg, J.4    Cao, Y.5
  • 27
    • 32944474182 scopus 로고    scopus 로고
    • VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature
    • Kamba, T. et al. VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature. Am. J. Physiol. Heart Circ. Physiol. 290, H560-H576 (2006).
    • (2006) Am. J. Physiol. Heart Circ. Physiol. , vol.290
    • Kamba, T.1
  • 28
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman, J. M. & Halaas, J. L. Leptin and the regulation of body weight in mammals. Nature 395, 763-770 (1998).
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 29
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • Yamauchi, T. et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423, 762-769 (2003).
    • (2003) Nature , vol.423 , pp. 762-769
    • Yamauchi, T.1
  • 30
    • 34447639114 scopus 로고    scopus 로고
    • Endothelial dysfunction in insulin resistance and type 2 diabetes
    • Jansson, P. A. Endothelial dysfunction in insulin resistance and type 2 diabetes. J. Intern. Med. 262, 173-183 (2007).
    • (2007) J. Intern. Med. , vol.262 , pp. 173-183
    • Jansson, P.A.1
  • 31
    • 57749177096 scopus 로고    scopus 로고
    • Endothelial dysfunction and diabetes: Roles of hyperglycemia, impaired insulin signaling and obesity
    • Bakker, W., Eringa, E. C., Sipkema, P. & van Hinsbergh, V. W. Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity. Cell Tissue Res. 335, 165-189 (2009)
    • (2009) Cell Tissue Res. , vol.335 , pp. 165-189
    • Bakker, W.1    Eringa, E.C.2    Sipkema, P.3    Van Hinsbergh, V.W.4
  • 32
    • 69949093803 scopus 로고    scopus 로고
    • Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications
    • Goldberg, R. B. Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications. J. Clin. Endocrinol. Metab. 94, 3171-3182 (2009).
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 3171-3182
    • Goldberg, R.B.1
  • 33
    • 70349484670 scopus 로고    scopus 로고
    • Mechanisms of obesity and related pathologies: The macro-and microcirculation of adipose tissue
    • Rutkowski, J. M., Davis, K. E. & Scherer, P. E. Mechanisms of obesity and related pathologies: the macro-and microcirculation of adipose tissue. FEBS J. 276, 5738-5746 (2009).
    • (2009) FEBS J. , vol.276 , pp. 5738-5746
    • Rutkowski, J.M.1    Davis, K.E.2    Scherer, P.E.3
  • 34
    • 0032508682 scopus 로고    scopus 로고
    • Biological action of leptin as an angiogenic factor
    • Sierra-Honigmann, M. R. et al. Biological action of leptin as an angiogenic factor. Science 281, 1683-1686 (1998).
    • (1998) Science , vol.281 , pp. 1683-1686
    • Sierra-Honigmann, M.R.1
  • 35
    • 32944478021 scopus 로고    scopus 로고
    • Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells
    • Aleffi, S. et al. Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells. Hepatology 42, 1339-1348 (2005).
    • (2005) Hepatology , vol.42 , pp. 1339-1348
    • Aleffi, S.1
  • 36
    • 0025344027 scopus 로고
    • 1-Butyryl-glycerol: A novel angiogenesis factor secreted by differentiating adipocytes
    • Dobson, D. E. et al. 1-Butyryl-glycerol: a novel angiogenesis factor secreted by differentiating adipocytes. Cell 61, 223-230 (1990).
    • (1990) Cell , vol.61 , pp. 223-230
    • Dobson, D.E.1
  • 37
    • 1442354888 scopus 로고    scopus 로고
    • Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis
    • Brakenhielm, E. et al. Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc. Natl Acad. Sci. USA 101, 2476-2481 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 2476-2481
    • Brakenhielm, E.1
  • 38
    • 42149117692 scopus 로고    scopus 로고
    • Adiponectin inhibits vascular endothelial growth factor-induced migration of human coronary artery endothelial cells
    • Mahadev, K. et al. Adiponectin inhibits vascular endothelial growth factor-induced migration of human coronary artery endothelial cells. Cardiovasc. Res. 78, 376-384 (2008).
    • (2008) Cardiovasc. Res. , vol.78 , pp. 376-384
    • Mahadev, K.1
  • 39
  • 40
    • 33845806853 scopus 로고    scopus 로고
    • Adiponectin modulates the glycogen synthase kinase-3β/β-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice
    • Wang, Y. et al. Adiponectin modulates the glycogen synthase kinase-3β/β-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice. Cancer Res. 66, 11462-11470 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 11462-11470
    • Wang, Y.1
  • 41
    • 24944489186 scopus 로고    scopus 로고
    • Modulation of angiogenesis during adipose tissue development in murine models of obesity
    • Voros, G. et al. Modulation of angiogenesis during adipose tissue development in murine models of obesity. Endocrinology 146, 4545-4554 (2005).
    • (2005) Endocrinology , vol.146 , pp. 4545-4554
    • Voros, G.1
  • 42
    • 66149164443 scopus 로고    scopus 로고
    • Proangiogenic contribution of adiponectin toward mammary tumor growth in vivo
    • Landskroner-Eiger, S. et al. Proangiogenic contribution of adiponectin toward mammary tumor growth in vivo. Clin. Cancer Res. 15, 3265-3276 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , pp. 3265-3276
    • Landskroner-Eiger, S.1
  • 45
    • 34047119110 scopus 로고    scopus 로고
    • Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation
    • Hosogai, N. et al. Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation. Diabetes 56, 901-911 (2007).
    • (2007) Diabetes , vol.56 , pp. 901-911
    • Hosogai, N.1
  • 46
    • 47849121225 scopus 로고    scopus 로고
    • Hypoxia in adipose tissue: A basis for the dysregulation of tissue function in obesity?
    • Trayhurn, P., Wang, B. & Wood, I. S. Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity? Br. J. Nutr. 100, 227-235 (2008).
    • (2008) Br. J. Nutr. , vol.100 , pp. 227-235
    • Trayhurn, P.1    Wang, B.2    Wood, I.S.3
  • 47
    • 33750286135 scopus 로고    scopus 로고
    • The multifaceted circulating endothelial cell in cancer: Towards marker and target identification
    • Bertolini, F., Shaked, Y., Mancuso, P. & Kerbel, R. S. The multifaceted circulating endothelial cell in cancer: towards marker and target identification. Nature Rev. Cancer 6, 835-845 (2006).
    • (2006) Nature Rev. Cancer , vol.6 , pp. 835-845
    • Bertolini, F.1    Shaked, Y.2    Mancuso, P.3    Kerbel, R.S.4
  • 48
    • 0035160312 scopus 로고    scopus 로고
    • Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
    • Lyden, D. et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nature Med. 7, 1194-1201 (2001).
    • (2001) Nature Med. , vol.7 , pp. 1194-1201
    • Lyden, D.1
  • 49
    • 33749005405 scopus 로고    scopus 로고
    • Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors
    • Shaked, Y. et al. Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors. Science 313, 1785-1787 (2006).
    • (2006) Science , vol.313 , pp. 1785-1787
    • Shaked, Y.1
  • 51
    • 3142663241 scopus 로고    scopus 로고
    • Mesenchymal stem cells and their potential as cardiac therapeutics
    • Pittenger, M. F. & Martin, B. J. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ. Res. 95, 9-20 (2004).
    • (2004) Circ. Res. , vol.95 , pp. 9-20
    • Pittenger, M.F.1    Martin, B.J.2
  • 52
    • 0033850535 scopus 로고    scopus 로고
    • Potential use of stem cells from bone marrow to repair the extracellular matrix and the central nervous system
    • Prockop, D. J. et al. Potential use of stem cells from bone marrow to repair the extracellular matrix and the central nervous system. Biochem. Soc. Trans. 28, 341-345 (2000).
    • (2000) Biochem. Soc. Trans. , vol.28 , pp. 341-345
    • Prockop, D.J.1
  • 53
    • 35348831024 scopus 로고    scopus 로고
    • Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis
    • Wu, Y., Chen, L., Scott, P. G. & Tredget, E. E. Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis. Stem Cells 25, 2648-2659 (2007).
    • (2007) Stem Cells , vol.25 , pp. 2648-2659
    • Wu, Y.1    Chen, L.2    Scott, P.G.3    Tredget, E.E.4
  • 56
    • 37349076286 scopus 로고    scopus 로고
    • Resident endothelial precursors in muscle, adipose, and dermis contribute to postnatal vasculogenesis
    • Grenier, G. et al. Resident endothelial precursors in muscle, adipose, and dermis contribute to postnatal vasculogenesis. Stem Cells 25, 3101-3110 (2007).
    • (2007) Stem Cells , vol.25 , pp. 3101-3110
    • Grenier, G.1
  • 57
    • 54949120976 scopus 로고    scopus 로고
    • Medicine. Can we nip obesity in its vascular bud?
    • Kahn, C. R. Medicine. Can we nip obesity in its vascular bud? Science 322, 542-543 (2008).
    • (2008) Science , vol.322 , pp. 542-543
    • Kahn, C.R.1
  • 58
    • 34248372084 scopus 로고    scopus 로고
    • Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages
    • Timmons, J. A. et al. Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages. Proc. Natl Acad. Sci. USA 104, 4401-4406 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 4401-4406
    • Timmons, J.A.1
  • 59
    • 0034613375 scopus 로고    scopus 로고
    • Function of GATA transcription factors in preadipocyte-adipocyte transition
    • Tong, Q. et al. Function of GATA transcription factors in preadipocyte-adipocyte transition. Science 290, 134-138 (2000).
    • (2000) Science , vol.290 , pp. 134-138
    • Tong, Q.1
  • 60
    • 50049122271 scopus 로고    scopus 로고
    • PRDM16 controls a brown fat/skeletal muscle switch
    • Seale, P. et al. PRDM16 controls a brown fat/skeletal muscle switch. Nature 454, 961-967 (2008).
    • (2008) Nature , vol.454 , pp. 961-967
    • Seale, P.1
  • 61
    • 3042786130 scopus 로고    scopus 로고
    • Angiogenesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice
    • Brakenhielm, E. et al. Angiogenesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice. Circ. Res. 94, 1579-1588 (2004).
    • (2004) Circ. Res. , vol.94 , pp. 1579-1588
    • Brakenhielm, E.1
  • 62
    • 0036678477 scopus 로고    scopus 로고
    • Adipose tissue mass can be regulated through the vasculature
    • Rupnick, M. A. et al. Adipose tissue mass can be regulated through the vasculature. Proc. Natl Acad. Sci. USA 99, 10730-10735 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 10730-10735
    • Rupnick, M.A.1
  • 63
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • O'Reilly, M. S. et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79, 315-328 (1994).
    • (1994) Cell , vol.79 , pp. 315-328
    • O'Reilly, M.S.1
  • 64
    • 0031454617 scopus 로고    scopus 로고
    • Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
    • O'Reilly, M. S. et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 88, 277-285 (1997).
    • (1997) Cell , vol.88 , pp. 277-285
    • O'Reilly, M.S.1
  • 65
    • 63749109585 scopus 로고    scopus 로고
    • Blockade of VEGFR2 and not VEGFR1 can limit diet-induced fat tissue expansion: Role of local versus bone marrow-derived endothelial cells
    • Tam, J. et al. Blockade of VEGFR2 and not VEGFR1 can limit diet-induced fat tissue expansion: role of local versus bone marrow-derived endothelial cells. PLoS ONE 4, e4974 (2009).
    • (2009) PLoS ONE , vol.4
    • Tam, J.1
  • 66
    • 0345900899 scopus 로고    scopus 로고
    • Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis
    • Fukumura, D. et al. Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis. Circ. Res. 93, e88-97 (2003).
    • (2003) Circ. Res. , vol.93
    • Fukumura, D.1
  • 67
    • 34248143523 scopus 로고    scopus 로고
    • Assessment of the anti-obesity effects of the TNP-470 analog, CKD-732
    • Kim, Y. M. et al. Assessment of the anti-obesity effects of the TNP-470 analog, CKD-732. J. Mol. Endocrinol. 38, 455-465 (2007).
    • (2007) J. Mol. Endocrinol. , vol.38 , pp. 455-465
    • Kim, Y.M.1
  • 68
    • 2342586114 scopus 로고    scopus 로고
    • Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470
    • Satchi-Fainaro, R. et al. Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470. Nature Med. 10, 255-261 (2004).
    • (2004) Nature Med. , vol.10 , pp. 255-261
    • Satchi-Fainaro, R.1
  • 69
    • 46449091277 scopus 로고    scopus 로고
    • Molecular mechanisms and therapeutic development of angiogenesis inhibitors
    • Cao, Y. Molecular mechanisms and therapeutic development of angiogenesis inhibitors. Adv. Cancer Res. 100, 113-131 (2008).
    • (2008) Adv. Cancer Res. , vol.100 , pp. 113-131
    • Cao, Y.1
  • 70
    • 70349807690 scopus 로고    scopus 로고
    • Improvement of antiangiogenic cancer therapy by understanding the mechanisms of angiogenic factor interplay and drug resistance
    • Cao, Y., Zhong, W. & Sun, Y. Improvement of antiangiogenic cancer therapy by understanding the mechanisms of angiogenic factor interplay and drug resistance. Semin. Cancer Biol. 19, 338-343 (2009).
    • (2009) Semin. Cancer Biol. , vol.19 , pp. 338-343
    • Cao, Y.1    Zhong, W.2    Sun, Y.3
  • 71
    • 2942703809 scopus 로고    scopus 로고
    • Reversal of obesity by targeted ablation of adipose tissue
    • Kolonin, M. G., Saha, P. K., Chan, L., Pasqualini, R. & Arap, W. Reversal of obesity by targeted ablation of adipose tissue. Nature Med. 10, 625-632 (2004).
    • (2004) Nature Med. , vol.10 , pp. 625-632
    • Kolonin, M.G.1    Saha, P.K.2    Chan, L.3    Pasqualini, R.4    Arap, W.5
  • 72
    • 33846577833 scopus 로고    scopus 로고
    • Activation of PPARβ/δ induces endothelial cell proliferation and angiogenesis
    • Piqueras, L. et al. Activation of PPARβ/δ induces endothelial cell proliferation and angiogenesis. Arterioscler. Thromb. Vasc. Biol. 27, 63-69 (2007).
    • (2007) Arterioscler. Thromb. Vasc. Biol. , vol.27 , pp. 63-69
    • Piqueras, L.1
  • 73
    • 57049122852 scopus 로고    scopus 로고
    • Enhanced angiogenesis in obesity and in response to PPARg activators through adipocyte VEGF and ANGPTL4 production
    • Gealekman, O. et al. Enhanced angiogenesis in obesity and in response to PPARg activators through adipocyte VEGF and ANGPTL4 production. Am. J. Physiol. Endocrinol. Metab. 295, E1056-E1064 (2008).
    • (2008) Am. J. Physiol. Endocrinol. Metab. , vol.295
    • Gealekman, O.1
  • 74
    • 13844280447 scopus 로고    scopus 로고
    • Effect of matrix metalloproteinase inhibition on adipose tissue development
    • Demeulemeester, D., Collen, D. & Lijnen, H. R. Effect of matrix metalloproteinase inhibition on adipose tissue development. Biochem. Biophys. Res. Commun. 329, 105-110 (2005).
    • (2005) Biochem. Biophys. Res. Commun. , vol.329 , pp. 105-110
    • Demeulemeester, D.1    Collen, D.2    Lijnen, H.R.3
  • 75
    • 0038823617 scopus 로고    scopus 로고
    • Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation
    • Chavey, C. et al. Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation. J. Biol. Chem. 278, 11888-11896 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 11888-11896
    • Chavey, C.1
  • 76
    • 0036120713 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibition impairs adipose tissue development in mice
    • Lijnen, H. R. et al. Matrix metalloproteinase inhibition impairs adipose tissue development in mice. Arterioscler Thromb. Vasc. Biol. 22, 374-379 (2002).
    • (2002) Arterioscler Thromb. Vasc. Biol. , vol.22 , pp. 374-379
    • Lijnen, H.R.1
  • 77
    • 34249945830 scopus 로고    scopus 로고
    • On the role of placental growth factor in murine adipogenesis
    • Christiaens, V., Voros, G., Scroyen, I. & Lijnen, H. R. On the role of placental growth factor in murine adipogenesis. Thromb. Res. 120, 399-405 (2007).
    • (2007) Thromb. Res. , vol.120 , pp. 399-405
    • Christiaens, V.1    Voros, G.2    Scroyen, I.3    Lijnen, H.R.4
  • 78
    • 33750858405 scopus 로고    scopus 로고
    • Impaired adipose tissue development in mice with inactivation of placental growth factor function
    • Lijnen, H. R. et al. Impaired adipose tissue development in mice with inactivation of placental growth factor function. Diabetes 55, 2698-2704 (2006).
    • (2006) Diabetes , vol.55 , pp. 2698-2704
    • Lijnen, H.R.1
  • 79
    • 65349182940 scopus 로고    scopus 로고
    • Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice
    • Ejaz, A., Wu, D., Kwan, P. & Meydani, M. Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice. J. Nutr. 139, 919-925 (2009).
    • (2009) J. Nutr. , vol.139 , pp. 919-925
    • Ejaz, A.1    Wu, D.2    Kwan, P.3    Meydani, M.4
  • 80
    • 67349178585 scopus 로고    scopus 로고
    • Interleukin-17A inhibits adipocyte differentiation in human mesenchymal stem cells and regulates pro-inflammatory responses in adipocytes
    • Shin, J. H., Shin, D. W. & Noh, M. Interleukin-17A inhibits adipocyte differentiation in human mesenchymal stem cells and regulates pro-inflammatory responses in adipocytes. Biochem. Pharmacol. 77, 1835-1844 (2009).
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 1835-1844
    • Shin, J.H.1    Shin, D.W.2    Noh, M.3
  • 81
    • 84950170873 scopus 로고    scopus 로고
    • Can EGCG reduce abdominal fat in obese subjects?
    • Hill, A. M. et al. Can EGCG reduce abdominal fat in obese subjects? J. Am. Coll. Nutr. 26, 396S-402S (2007).
    • (2007) J. Am. Coll. Nutr. , vol.26
    • Hill, A.M.1
  • 83
    • 26944480126 scopus 로고    scopus 로고
    • Green tea polyphenol epigallocatechin gallate inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes
    • Lin, J., Della-Fera, M. A. & Baile, C. A. Green tea polyphenol epigallocatechin gallate inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes. Obes. Res. 13, 982-990 (2005).
    • (2005) Obes. Res. , vol.13 , pp. 982-990
    • Lin, J.1    Della-Fera, M.A.2    Baile, C.A.3
  • 84
    • 20044383992 scopus 로고    scopus 로고
    • Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation
    • Klaus, S., Pultz, S., Thone-Reineke, C. & Wolfram, S. Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation. Int. J. Obes. (Lond.) 29, 615-623 (2005).
    • (2005) Int. J. Obes. (Lond.) , vol.29 , pp. 615-623
    • Klaus, S.1    Pultz, S.2    Thone-Reineke, C.3    Wolfram, S.4
  • 85
    • 0033118504 scopus 로고    scopus 로고
    • Angiogenesis inhibited by drinking tea
    • Cao, Y. & Cao, R. Angiogenesis inhibited by drinking tea. Nature 398, 381 (1999).
    • (1999) Nature , vol.398 , pp. 381
    • Cao, Y.1    Cao, R.2
  • 86
    • 33847733103 scopus 로고    scopus 로고
    • Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions
    • Yamauchi, T. et al. Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nature Med. 13, 332-339 (2007).
    • (2007) Nature Med. , vol.13 , pp. 332-339
    • Yamauchi, T.1
  • 87
    • 2442716239 scopus 로고    scopus 로고
    • Fat hormones pull their weight in the CNS
    • Seeley, R. J., D'Alessio, D. A. & Woods, S. C. Fat hormones pull their weight in the CNS. Nature Med. 10, 454-455 (2004).
    • (2004) Nature Med. , vol.10 , pp. 454-455
    • Seeley, R.J.1    D'Alessio, D.A.2    Woods, S.C.3
  • 88
    • 0034881956 scopus 로고    scopus 로고
    • You are what you secrete
    • Saltiel, A. R. You are what you secrete. Nature Med. 7, 887-888 (2001).
    • (2001) Nature Med. , vol.7 , pp. 887-888
    • Saltiel, A.R.1
  • 89
    • 0032568376 scopus 로고    scopus 로고
    • Life without leptin
    • O'Rahilly, S. Life without leptin. Nature 392, 330-331 (1998).
    • (1998) Nature , vol.392 , pp. 330-331
    • O'Rahilly, S.1
  • 90
    • 0034611675 scopus 로고    scopus 로고
    • Obesity in the new millennium
    • Friedman, J. M. Obesity in the new millennium. Nature 404, 632-634 (2000).
    • (2000) Nature , vol.404 , pp. 632-634
    • Friedman, J.M.1
  • 91
    • 0028793697 scopus 로고
    • Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
    • Frederich, R. C. et al. Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nature Med. 1, 1311-1314 (1995).
    • (1995) Nature Med. , vol.1 , pp. 1311-1314
    • Frederich, R.C.1
  • 92
    • 16944364768 scopus 로고    scopus 로고
    • Human leptin levels are pulsatile and inversely related to pituitary-adrenal function
    • Licinio, J. et al. Human leptin levels are pulsatile and inversely related to pituitary-adrenal function. Nature Med. 3, 575-579 (1997).
    • (1997) Nature Med. , vol.3 , pp. 575-579
    • Licinio, J.1
  • 93
    • 37549040613 scopus 로고    scopus 로고
    • Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
    • Miller, K. et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N. Engl. J. Med. 357, 2666-2676 (2007).
    • (2007) N. Engl. J. Med. , vol.357 , pp. 2666-2676
    • Miller, K.1
  • 95
    • 66149086950 scopus 로고    scopus 로고
    • Positive and negative modulation of angio-genesis by VEGFR1 ligands
    • Cao, Y. Positive and negative modulation of angio-genesis by VEGFR1 ligands. Sci. Signal. 2, re1 (2009).
    • (2009) Sci. Signal. , vol.2
    • Cao, Y.1
  • 96
    • 30744479430 scopus 로고    scopus 로고
    • Angiogenesis in life, disease and medicine
    • Carmeliet, P. Angiogenesis in life, disease and medicine. Nature 438, 932-936 (2005).
    • (2005) Nature , vol.438 , pp. 932-936
    • Carmeliet, P.1
  • 97
    • 30744449235 scopus 로고    scopus 로고
    • Angiogenesis as a therapeutic target
    • Ferrara, N. & Kerbel, R. S. Angiogenesis as a therapeutic target. Nature 438, 967-974 (2005).
    • (2005) Nature , vol.438 , pp. 967-974
    • Ferrara, N.1    Kerbel, R.S.2
  • 98
    • 22444447946 scopus 로고    scopus 로고
    • Common mechanisms of nerve and blood vessel wiring
    • Carmeliet, P. & Tessier-Lavigne, M. Common mechanisms of nerve and blood vessel wiring. Nature 436, 193-200 (2005).
    • (2005) Nature , vol.436 , pp. 193-200
    • Carmeliet, P.1    Tessier-Lavigne, M.2
  • 99
    • 0033793881 scopus 로고    scopus 로고
    • VEGF gene therapy: Stimulating angiogenesis or angioma-genesis?
    • Carmeliet, P. VEGF gene therapy: stimulating angiogenesis or angioma-genesis? Nature Med. 6, 1102-1103 (2000).
    • (2000) Nature Med , vol.6 , pp. 1102-1103
    • Carmeliet, P.1
  • 100
    • 0035047885 scopus 로고    scopus 로고
    • Vascular endothelial growth factor enhances atherosclerotic plaque progression
    • Celletti, F. L. et al. Vascular endothelial growth factor enhances atherosclerotic plaque progression. Nature Med. 7, 425-429 (2001).
    • (2001) Nature Med. , vol.7 , pp. 425-429
    • Celletti, F.L.1
  • 101
    • 55549090302 scopus 로고    scopus 로고
    • Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma
    • Jinnin, M. et al. Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma. Nature Med. 14, 1236-1246 (2008).
    • (2008) Nature Med. , vol.14 , pp. 1236-1246
    • Jinnin, M.1
  • 102
    • 0035048967 scopus 로고    scopus 로고
    • To o many vessels? Not enough? the wrong kind? the VEGF debate continues
    • Ware, J. A. To o many vessels? Not enough? The wrong kind? The VEGF debate continues. Nature Med. 7, 403-404 (2001).
    • (2001) Nature Med. , vol.7 , pp. 403-404
    • Ware, J.A.1
  • 103
    • 0034611791 scopus 로고    scopus 로고
    • Obesity as a medical problem
    • Kopelman, P. G. Obesity as a medical problem. Nature 404, 635-643 (2000).
    • (2000) Nature , vol.404 , pp. 635-643
    • Kopelman, P.G.1
  • 104
    • 42549162394 scopus 로고    scopus 로고
    • Medicine. Bypassing medicine to treat diabetes
    • Couzin, J. Medicine. Bypassing medicine to treat diabetes. Science 320, 438-440 (2008).
    • (2008) Science , vol.320 , pp. 438-440
    • Couzin, J.1
  • 106
    • 34249018265 scopus 로고    scopus 로고
    • Obesity and prostate cancer: A role for adipokines
    • Mistry, T., Digby, J. E., Desai, K. M. & Randeva, H. S. Obesity and prostate cancer: a role for adipokines. Eur. Urol. 52, 46-53 (2007).
    • (2007) Eur. Urol. , vol.52 , pp. 46-53
    • Mistry, T.1    Digby, J.E.2    Desai, K.M.3    Randeva, H.S.4
  • 107
    • 17244378434 scopus 로고    scopus 로고
    • Pegaptanib and age-related macular degeneration
    • author reply 352, 1720-1721 (2005)
    • Rakic, J. M., Blaise, P. & Foidart, J. M. Pegaptanib and age-related macular degeneration. N. Engl J. Med. 352, 1720-1721 (2005); author reply 352, 1720-1721 (2005).
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1720-1721
    • Rakic, J.M.1    Blaise, P.2    Foidart, J.M.3
  • 108
    • 33749451356 scopus 로고    scopus 로고
    • Ranibizumab versus verteporfin for neovascular age-related macular degeneration
    • Brown, D. M. et al. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N. Engl. J. Med. 355, 1432-1444 (2006).
    • (2006) N. Engl. J. Med. , vol.355 , pp. 1432-1444
    • Brown, D.M.1
  • 109
    • 33749445317 scopus 로고    scopus 로고
    • Ranibizumab for neovascular age-related macular degeneration
    • Rosenfeld, P. J. et al. Ranibizumab for neovascular age-related macular degeneration. N. Engl. J. Med. 355, 1419-1431 (2006).
    • (2006) N. Engl. J. Med. , vol.355 , pp. 1419-1431
    • Rosenfeld, P.J.1
  • 110
    • 0034479597 scopus 로고    scopus 로고
    • Clinical protocol: Phase i trial to evaluate the safety of H5.020CMV.PDGF-B for the treatment of a diabetic insensate foot ulcer
    • Margolis, D. J., Crombleholme, T. & Herlyn, M. Clinical protocol: Phase I trial to evaluate the safety of H5.020CMV.PDGF-B for the treatment of a diabetic insensate foot ulcer. Wound Repair Regen. 8, 480-493 (2000).
    • (2000) Wound Repair Regen. , vol.8 , pp. 480-493
    • Margolis, D.J.1    Crombleholme, T.2    Herlyn, M.3
  • 113
    • 49349103253 scopus 로고    scopus 로고
    • Intravitreous anti-VEGF for diabetic retinopathy: Hopes and fears for a new therapeutic strategy
    • Simo, R. & Hernandez, C. Intravitreous anti-VEGF for diabetic retinopathy: hopes and fears for a new therapeutic strategy. Diabetologia 51, 1574-1580 (2008).
    • (2008) Diabetologia , vol.51 , pp. 1574-1580
    • Simo, R.1    Hernandez, C.2
  • 115
    • 0034056971 scopus 로고    scopus 로고
    • Becaplermin gel (PDGF-BB) as topical wound therapy
    • Plastic Surgery Educational Foundation DATA Committee
    • Ladin, D. Becaplermin gel (PDGF-BB) as topical wound therapy. Plastic Surgery Educational Foundation DATA Committee. Plast. Reconstr. Surg. 105, 1230-1231 (2000).
    • (2000) Plast. Reconstr. Surg. , vol.105 , pp. 1230-1231
    • Ladin, D.1
  • 116
    • 33745513688 scopus 로고    scopus 로고
    • Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity ulcers
    • discussion 150S-151S
    • Steed, D. L. Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity ulcers. Plast. Reconstr. Surg. 11 7, 143S-149S; discussion 150S-151S (2006).
    • (2006) Plast. Reconstr. Surg. , vol.117
    • Steed, D.L.1
  • 117
    • 12344266697 scopus 로고    scopus 로고
    • How obesity causes diabetes: Not a tall tale
    • Lazar, M. A. How obesity causes diabetes: not a tall tale. Science 307, 373-375 (2005).
    • (2005) Science , vol.307 , pp. 373-375
    • Lazar, M.A.1
  • 118
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPARg
    • Lehrke, M. & Lazar, M. A. The many faces of PPARg. Cell 123, 993-999 (2005).
    • (2005) Cell , vol.123 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 119
    • 58649105336 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice
    • e4
    • Menghini, R. et al. Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice. Gastroenterology 136, 663-672 e4 (2009).
    • (2009) Gastroenterology , vol.136 , pp. 663-672
    • Menghini, R.1
  • 120
    • 0033782028 scopus 로고    scopus 로고
    • Leptin in the regulation of immunity, inflammation, and hematopoiesis
    • Fantuzzi, G. & Faggioni, R. Leptin in the regulation of immunity, inflammation, and hematopoiesis. J. Leukoc. Biol. 68, 437-446 (2000).
    • (2000) J. Leukoc. Biol. , vol.68 , pp. 437-446
    • Fantuzzi, G.1    Faggioni, R.2
  • 121
    • 33947520741 scopus 로고    scopus 로고
    • Angiogenic role of LYVE-1-positive macrophages in adipose tissue
    • Cho, C. H. et al. Angiogenic role of LYVE-1-positive macrophages in adipose tissue. Circ. Res. 100, e47-57 (2007).
    • (2007) Circ. Res. , vol.100
    • Cho, C.H.1
  • 122
    • 38549095046 scopus 로고    scopus 로고
    • PPARa deficiency in inflammatory cells suppresses tumor growth
    • Kaipainen, A. et al. PPARa deficiency in inflammatory cells suppresses tumor growth. PLoS ONE 2, e260 (2007).
    • (2007) PLoS ONE , vol.2
    • Kaipainen, A.1
  • 123
    • 39749140405 scopus 로고    scopus 로고
    • HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
    • Arany, Z. et al. HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α. Nature 451, 1008-1012 (2008).
    • (2008) Nature , vol.451 , pp. 1008-1012
    • Arany, Z.1
  • 124
    • 38349046738 scopus 로고    scopus 로고
    • Angiogenic growth factor synergism in a murine tissue engineering model of angiogenesis and adipogenesis
    • Rophael, J. A. et al. Angiogenic growth factor synergism in a murine tissue engineering model of angiogenesis and adipogenesis. Am. J. Pathol. 171, 2048-2057 (2007).
    • (2007) Am. J. Pathol. , vol.171 , pp. 2048-2057
    • Rophael, J.A.1
  • 125
    • 33745370098 scopus 로고    scopus 로고
    • Human adipose tissue-derived mesenchymal stem cells improve postnatal neovascularization in a mouse model of hindlimb ischemia
    • Moon, M. H. et al. Human adipose tissue-derived mesenchymal stem cells improve postnatal neovascularization in a mouse model of hindlimb ischemia. Cell Physiol. Biochem. 17, 279-290 (2006).
    • (2006) Cell Physiol. Biochem. , vol.17 , pp. 279-290
    • Moon, M.H.1
  • 126
    • 33746576102 scopus 로고    scopus 로고
    • Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy
    • Nakagami, H. et al. Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy. J. Atheroscler Thromb. 13, 77-81 (2006).
    • (2006) J. Atheroscler Thromb. , vol.13 , pp. 77-81
    • Nakagami, H.1
  • 127
    • 33646103658 scopus 로고    scopus 로고
    • Fat tissue: An underappreciated source of stem cells for biotechnology
    • Fraser, J. K., Wulur, I., Alfonso, Z. & Hedrick, M. H. Fat tissue: an underappreciated source of stem cells for biotechnology. Trends Biotechnol. 24, 150-154 (2006).
    • (2006) Trends Biotechnol. , vol.24 , pp. 150-154
    • Fraser, J.K.1    Wulur, I.2    Alfonso, Z.3    Hedrick, M.H.4
  • 128
    • 33751340808 scopus 로고    scopus 로고
    • Vascular fate of adipose tissue-derived adult stromal cells in the ischemic murine brain: A combined imaging-histological study
    • Kubis, N. et al. Vascular fate of adipose tissue-derived adult stromal cells in the ischemic murine brain: a combined imaging-histological study. Neuroimage 34, 1-11 (2007).
    • (2007) Neuroimage , vol.34 , pp. 1-11
    • Kubis, N.1
  • 129
    • 41949098133 scopus 로고    scopus 로고
    • Effects of surface-modified scaffolds on the growth and differentiation of mouse adipose-derived stromal cells
    • Lin, J., Lindsey, M. L., Zhu, B., Agrawal, C. M. & Bailey, S. R. Effects of surface-modified scaffolds on the growth and differentiation of mouse adipose-derived stromal cells. J. Tissue Eng. Regen. Med. 1, 211-217 (2007).
    • (2007) J. Tissue Eng. Regen. Med. , vol.1 , pp. 211-217
    • Lin, J.1    Lindsey, M.L.2    Zhu, B.3    Agrawal, C.M.4    Bailey, S.R.5
  • 130
    • 66849111706 scopus 로고    scopus 로고
    • Visfatin (nicotinomide phosphoribosyl-transferase/pre-B cell colony-enhancing factor) activates eNOS via Akt and MAP kinases and improves endothelial function
    • 7 Apr doi:10.1152/ ajpendo.90780.2008
    • Lovren, F. et al. Visfatin (nicotinomide phosphoribosyl-transferase/pre-B cell colony-enhancing factor) activates eNOS via Akt and MAP kinases and improves endothelial function. Am. J. Physiol. Endocrinol. Metab. 7 Apr 2009 (doi:10.1152/ ajpendo.90780.2008).
    • (2009) Am. J. Physiol. Endocrinol. Metab.
    • Lovren, F.1
  • 131
    • 49549120896 scopus 로고    scopus 로고
    • Fate of amnion-derived stem cells transplanted to the fetal rat brain: Migration, survival and differentiation
    • Marcus, A. J., Coyne, T. M., Black, I. B. & Woodbury, D. Fate of amnion-derived stem cells transplanted to the fetal rat brain: migration, survival and differentiation. J. Cell. Mol. Med. 12, 1256-1264 (2008).
    • (2008) J. Cell. Mol. Med. , vol.12 , pp. 1256-1264
    • Marcus, A.J.1    Coyne, T.M.2    Black, I.B.3    Woodbury, D.4
  • 132
    • 67650811823 scopus 로고    scopus 로고
    • Functional implications of CD34 expression in human adipose-derived stem/progenitor cells
    • Suga, H. et al. Functional implications of CD34 expression in human adipose-derived stem/progenitor cells. Stem Cells Dev. 18, 1201-1210 (2009).
    • (2009) Stem Cells Dev. , vol.18 , pp. 1201-1210
    • Suga, H.1
  • 133
    • 37849026091 scopus 로고    scopus 로고
    • A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks
    • Traktuev, D. O. et al. A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks. Circ. Res. 102, 77-85 (2008).
    • (2008) Circ. Res. , vol.102 , pp. 77-85
    • Traktuev, D.O.1
  • 134
    • 1842409029 scopus 로고    scopus 로고
    • Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese
    • Enerback, S. et al. Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese. Nature 387, 90-94 (1997).
    • (1997) Nature , vol.387 , pp. 90-94
    • Enerback, S.1
  • 135
    • 63049085192 scopus 로고    scopus 로고
    • A new twist on brown fat metabolism
    • Wallberg-Henriksson, H. & Zierath, J. R. A new twist on brown fat metabolism. Cell 137, 22-24 (2009).
    • (2009) Cell , vol.137 , pp. 22-24
    • Wallberg-Henriksson, H.1    Zierath, J.R.2
  • 136
    • 34447116241 scopus 로고    scopus 로고
    • Neuropeptide y acts directly in the periphery on fat tissue and mediates stress-induced obesity and metabolic syndrome
    • Kuo, L. E. et al. Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced obesity and metabolic syndrome. Nature Med. 13, 803-811 (2007).
    • (2007) Nature Med. , vol.13 , pp. 803-811
    • Kuo, L.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.