Visfatin activates eNOS via Akt and MAP kinases and improves endothelial cell function and angiogenesis in vitro and in vivo: Translational implications for atherosclerosis

American Journal of Physiology - Endocrinology and Metabolism

Volumn 296, Issue 6, 2009, Pages

  Lovren, Fina ^a,d   Pan, Yi ^a   Shukla, Praphulla C ^a   Quan, Adrian ^a,d   Teoh, Hwee ^a,b,c,d   Szmitko, Paul E ^b,d   Peterson, Mark D ^a   Gupta, Milan ^a,b,c,e   Al Omran, Mohammed ^f   Verma, Subodh ^a,b,c,f,g  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

^c Canadian Cardiovascular Research Network   (Canada)

^d Translational Traineeship Program in Atherosclerosis   (Canada)

^e William Osler Health Centre   (Canada)

^f KING KHALID UNIVERSITY HOSPITAL   (Saudi Arabia)

^g Translational Atherosclerosis Research Program   (Canada)

Author keywords

Atherosclerosis; Endothelial nitric oxide synthase; Endothelium; Mice; Mitogen activated protein kinase; Nitric oxide; Phosphatidylinositol 3 kinase; Protein kinase B; Visfatin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MATRIGEL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N(G) NITROARGININE METHYL ESTER; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; RECOMBINANT ENZYME; SIRTUIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANGIOGENESIS; ARTICLE; ATHEROSCLEROSIS; CELL MEMBRANE PERMEABILITY; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIMB ISCHEMIA; LIMB PERFUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA TRANSLATION;

ANIMALS; ATHEROSCLEROSIS; CELL DIVISION; COLLAGEN; CORONARY VESSELS; DRUG COMBINATIONS; DRUG IMPLANTS; ENDOTHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; ISCHEMIA; LAMININ; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NEOVASCULARIZATION, PHYSIOLOGIC; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NITRIC OXIDE SYNTHASE TYPE III; PROTEOGLYCANS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; TRANSFECTION; UMBILICAL VEINS; VEINS;

EID: 66849111706     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.90780.2008     Document Type: Article

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