Antioxidant and antiviral activities of silybin fatty acid conjugates

European Journal of Medicinal Chemistry

Volumn 45, Issue 3, 2010, Pages 1059-1067

  Gažák, Radek ^a   Purchartová, Kateřina ^a   Marhol, Petr ^a   Živná, Lucie ^a   Sedmera, Petr ^a   Valentová, Kateřina ^b   Kato, Nobuo ^c   Matsumura, Hiroyo ^c   Kaihatsu, Kunihiro ^c   Křen, Vladimír ^a  

^a INSTITUTE OF MICROBIOLOGY   (Czech Republic)

^b PALACKÝ UNIVERSITY   (Czech Republic)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

Antiviral; Influenza virus; Lipid peroxidation; Lipophilic derivatives; Silibinin; Silybin

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2 [2,3 DIHYDRO 2 ((CIS 11 EICOSENOYL) OXYMETHYL) 3 (4 HYDROXY 3 METHOXYPHENYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5,7 TRIHYDROXY 4H 1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 2 (BUTANOYLOXYMETHYL) 3 (4 HYDROXY 3 METHOXYPHENYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5,7 TRIHYDROXY 4H 1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 2 (DODECANOYLOXYMETHYL) 3 (4 HYDROXY 3 METHOXYPHENYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5,7 TRIHYDROXY 4H1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 2 (HEXADECANOYLOXYMETHYL) 3 (4 HYDROXY 3 METHOXYPHENYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5,7 TRIHYDROXY 4H 1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 3 (4 HYDROXY 3 METHOXYPHENYL) 2 ((CIS 9 OCTADECENOYL) OXYMETHYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5,7 TRIHYDROXY 4H 1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 3 (4 HYDROXY 3 METHOXYPHENYL) 2 ((CIS,CIS 9,12 OCTADECADIENOYL) OXYMETHYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5,7 TRIHYDROXY 4H 1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 3 (4 HYDROXY 3 METHOXYPHENYL) 2 (HYDROXYMETHYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5 DIHYDROXY 7 (CIS 11 EICOSENOYL)OXY 4H 1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 3 (4 HYDROXY 3 METHOXYPHENYL) 2 (HYDROXYMETHYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5 DIHYDROXY 7 (CIS 9 OCTADECENOYL)OXY 4H 1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 3 (4 HYDROXY 3 METHOXYPHENYL) 2 (HYDROXYMETHYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5 DIHYDROXY 7 (CIS,CIS 9,12 OCTADECADIENOYL)OXY 4H 1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 3 (4 HYDROXY 3 METHOXYPHENYL) 2 (HYDROXYMETHYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5 DIHYDROXY 7 DODECANOYLOXY 4H 1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 3 (4 HYDROXY 3 METHOXYPHENYL) 2 (HYDROXYMETHYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5 DIHYDROXY 7 HEXADECANOYLOXY 4H 1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 3 (4 HYDROXY 3 METHOXYPHENYL) 2 (HYDROXYMETHYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5 DIHYDROXY 7 OCTANOYLOXY 4H 1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 3 (4 HYDROXY 3 METHOXYPHENYL) 2 (HYDROXYMETHYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 7 BUTANOYLOXY 3,5 DIHYDROXY 4H 1 BENZOPYRAN 4 ONE; 2 [2,3 DIHYDRO 3 (4 HYDROXY 3 METHOXYPHENYL) 2 (OCTANOYLOXYMETHYL) 1,4 BENZODIOXIN 6 YL] 2,3 DIHYDRO 3,5,7 TRIHYDROXY 4H 1 BENZOPYRAN 4 ONE; ANTIOXIDANT; ANTIVIRUS AGENT; FATTY ACID DERIVATIVE; SILIBININ; UNCLASSIFIED DRUG;

ACYLATION; ANIMAL CELL; ANTIOXIDANT ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CONJUGATE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG SCREENING; DRUG STRUCTURE; ESTERIFICATION; INFLUENZA VIRUS; LIPID PEROXIDATION; NONHUMAN; STRUCTURE ACTIVITY RELATION;

EID: 75849127288     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.11.056     Document Type: Article

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