Epicatechin conjugated with fatty acid is a potent inhibitor of DNA polymerase and angiogenesis

Life Sciences

Volumn 80, Issue 17, 2007, Pages 1578-1585

  Matsubara, Kiminori ^a,b   Saito, Akiko ^c   Tanaka, Akira ^d   Nakajima, Noriyuki ^d   Akagi, Reiko ^a   Mori, Masaharu ^a   Mizushina, Yoshiyuki ^b  

^a OKAYAMA PREFECTURAL UNIVERSITY   (Japan)

^b KOBE GAKUIN UNIVERSITY   (Japan)

^c Biotechnology Center   (Japan)

^d TOYAMA PREFECTURAL UNIVERSITY   (Japan)

Author keywords

Angiogenesis; Aortic ring; Endothelial cells; Epicatechin; Fatty acid

Indexed keywords

3',4',5,7 TETRAHYDROXYFLAVAN 3 YL HEXADECANOATE EPICATECHIN; CATECHIN; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; DNA POLYMERASE; EPICATECHIN; FATTY ACID; PALMITIC ACID; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CELL STRAIN HL 60; CELL VIABILITY; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG CONJUGATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENDOTHELIUM CELL; ENZYME INHIBITION; EX VIVO STUDY; HUMAN; HUMAN CELL; IC 50; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; TEA; VASCULAR RING;

ACYLATION; ANGIOGENESIS INHIBITORS; ANIMALS; CAPILLARIES; CATECHIN; DNA-DIRECTED DNA POLYMERASE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HL-60 CELLS; HUMANS; MALE; MOLECULAR STRUCTURE; NEOVASCULARIZATION, PHYSIOLOGIC; PALMITIC ACID; RATS; RATS, WISTAR;

EID: 33947146587     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.01.049     Document Type: Article

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