Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation

Blood

Volumn 115, Issue 2, 2010, Pages 344-352

  Jabbour, Anissa M ^a,b   Daunt, Carmel P ^a   Green, Benjamin D ^a   Vogel, Sandra ^c   Gordon, Lavinia ^a   Lee, Rachel S ^d   Silke, Natasha ^a   Pearson, Richard B ^d   Vandenberg, Cassandra J ^e   Kelly, Priscilla N ^e   Nutt, Stephen L ^e   Strasser, Andreas ^e   Borner, Christoph ^c   Ekert, Paul G ^a,b  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF FREIBURG   (Germany)

^d PETER MACCALLUM CANCER CENTRE   (Australia)

^e WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 3; PROTEIN MDM2; PROTEIN P53; PUMA PROTEIN; TRANSCRIPTION FACTOR FKHRL1; APOPTOSIS REGULATORY PROTEIN; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; HOXB8 PROTEIN, MOUSE; MDM2 PROTEIN, MOUSE; PROTEIN BCL 2; PUMA PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CULTURE; CELL CYCLE ARREST; CELL SURVIVAL; CLONOGENIC ASSAY; CONTROLLED STUDY; DNA DAMAGE; GENE EXPRESSION; GENETIC TRANSCRIPTION; MOUSE; MYELOID PROGENITOR CELL; NONHUMAN; PRIORITY JOURNAL; UPREGULATION; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECT; GENE DELETION; GENETICS; METABOLISM; TIME; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; FORKHEAD TRANSCRIPTION FACTORS; GENE DELETION; HOMEODOMAIN PROTEINS; INTERLEUKIN-3; MICE; MYELOID PROGENITOR CELLS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MDM2; TIME FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 75649111252     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-07-230730     Document Type: Article

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