Gamma-ray resistance of regulatory CD4+CD25 +Foxp3+ T cells in mice

Radiation Research

Volumn 173, Issue 2, 2010, Pages 148-157

  Qu, Yanyan ^a   Jin, Shuguang ^b   Zhang, Aijun ^a,c   Zhang, Baojun ^a   Shi, Xiaoyun ^a   Wang, Junjie ^d   Zhao, Yong ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b BEIHUA UNIVERSITY   (China)

^c SHANDONG UNIVERSITY   (China)

^d PEKING UNIVERSITY THIRD HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BCL 2; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD; C57BL 6 MOUSE; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL DEATH; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; EFFECTOR CELL; FEMALE; GAMMA RADIATION; IMMUNE RESPONSE; IMMUNITY; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE; LYMPHOCYTE COUNT; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY; REGULATORY T LYMPHOCYTE; SPLEEN; THYMUS;

ANIMALS; ANTIGENS, CD4; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; FORKHEAD TRANSCRIPTION FACTORS; GAMMA RAYS; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MICE; MICE, INBRED C57BL; PROTO-ONCOGENE PROTEINS C-BCL-2; RADIATION TOLERANCE; T-LYMPHOCYTES, REGULATORY;

MUS;

EID: 75149196312     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR0978.1     Document Type: Article

References (49)

1. z natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol. Rev. 212, 8-27 (2006).
2. z regulatory T cell function in alloimmunity. J Immunol. 176, 329-334 (2006).
3. z regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Rev. 182, 18-32 (2001).
4. A. M. Gallegos and M. J. Bevan, Central tolerance: good but imperfect. Immunol. Rev. 209, 290-296 (2006).
5. K. A. Hogquist, T. A. Baldwin and S. C. Jameson, Central tolerance: learning self-control in the thymus. Nat. Rev. Immunol. 5, 772-782 (2005).
6. D. Mathis and C. Benoist, Back to central tolerance. Immunity 20, 509-516 (2004).
7. z regulatory T cells and their ligands: implications for immunotherapy. Immunity 20, 107-118 (2004).
8. z suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2, 389-400 (2002).
9. z regulatory T cells. Int. Immunol. 16, 1643-1656 (2004).
10. z T regulatory cells. Nat. Immunol. 4, 337-342 (2003).
11. F. Ramsdell, Foxp3 and natural regulatory T cells: key to a cell lineage? Immunity 19, 165-168 (2003).
12. z regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer. Exp. Dermatol. 13, 613-620 (2004).
13. z regulatory cells augments the generation of specific immune T cells in tumor-draining lymph nodes. J. Immunother. 25, 207-217 (2002).
14. E. Biagi, R. Rousseau, E. Yvon, M. Schwartz, G. Dotti, A. Foster, D. Havlik-Cooper, B. Grilley, A. Gee and M. Brenner, Responses to human CD40 ligand/human interleukin-2 autologous cell vaccine in patients with B-cell chronic lymphocytic leukemia. Clin. Cancer Res. 11, 6916-6923 (2005).
15. L. A. Ormandy, T. Hillemann, H. Wedemeyer, M. P. Manns, T. F. Greten and F. Korangy, Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma. Cancer Res. 65, 2457-2464 (2005).
16. N. G. Chakraborty, S. Chattopadhyay, S. Mehrotra, A. Chhabra and B. Mukherji, Regulatory T-cell response and tumor vaccine-induced cytotoxic T lymphocytes in human melanoma. Hum. Immunol. 65, 794-802 (2004).
17. z regulatory T-cell levels in patients with melanoma. Clin. Cancer Res. 9, 2551-2559 (2003).
18. z T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res. 61, 4766-4772 (2001).
19. C. Kudo-Saito, J. Schlom, K. Camphausen, C. N. Coleman and J. W. Hodge, The requirement of multimodal therapy (vaccine, local tumor radiation, and reduction of suppressor cells) to eliminate established tumors. Clin. Cancer Res. 11, 4533-4544 (2005).
20. B. J. Fisher, C. Scott, D. R. Macdonald, C. Coughlin and W. J. Curran, Phase I study of topotecan plus cranial radiation for glioblastoma multiforme: results of Radiation Therapy Oncology Group Trial 9507. J Clin. Oncol. 19, 1111-1117 (2001).
21. M. J. Pecaut, G. A. Nelson and D. S. Gridley, Dose and dose rate effects of whole-body gamma-irradiation: I. Lymphocytes and lymphoid organs. In Vivo 15, 195-208 (2001).
22. H. R. Park, S. K. Jo and S. G. Paik, The NK1.1zT cells alive in irradiated mice play an important role in a Th1/Th2 balance. Int. J Radiat. Biol. 82, 161-170 (2006).
23. Y. Sun, H. Li, A. N. Langnas and Y. Zhao, Altered allogeneic immune responses in middle-aged mice. Cell. Mol. Immunol. 1, 440-446 (2004).
24. Y. Sun, B. S. Ge, M. Kasai, C. Diffendaffer, N. Parks, H. Li, J. Peng, A. N. Langnas and Y. Zhao, Induction of regulatory T cells from mature T cells by allogeneic thymic epithelial cells in vitro. Transpl. Int. 19, 404-414 (2006).
25. z regulatory T cells in mice. Transplantation 82, 1484-1492 (2006).
26. z T cells in xenogeneic neonatal porcine thymus-grafted athymic mice. Am. J. Transplant. 6, 2841-2850 (2006).
27. 5 resident macrophages in mouse mixed allogeneic chimeras. J Mol. Med. 85, 1125-1135 (2007).
28. B. Zhang, B. Ge, X. Xia, J. Liu, L. Sun, E. Rao and Y. Zhao, Compatibility of porcine and human interleukin 2: implications for xenotransplantation. Xenotransplantation 13, 423-432 (2006).
29. high regulatory T cells. Blood 103, 2410-2416 (2004).
30. high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation. J Immunol. 174, 164-173 (2005).
31. z regulatory T cells. Trends Immunol. 25, 374-380 (2004).
32. z T cells. Cell. Mol. Immunol. 3, 189-195 (2006).
33. z regulatory T cells. Nat. Immunol. 4, 330-336 (2003).
34. z T cells: multiple pathways on the road. J. Cell Physiol. 211, 590-597 (2007).
35. z regulatory T cells in mice: potential implication for the treatment of autoimmune diseases. J. Mol. Med. 85, 1263-1270 (2007).
36. D. T. Chao, G. P. Linette, L. H. Boise, L. S. White, C. B. Thompson and S. J. Korsmeyer, Bcl-XL and Bcl-2 repress a common pathway of cell death. J. Exp. Med. 182, 821-828 (1995).
37. T. Urashima, H. Nagasawa, K. Wang, S. J. Adelstein, J. B. Little and A. I. Kassis, Induction of apoptosis in human tumor cells after exposure to Auger electrons: comparison with gamma-ray exposure. Nucl. Med. Biol. 33, 1055-1063 (2006).
38. N. Shinomiya, New concepts in radiation-induced apoptosis: 'premitotic apoptosis' and 'postmitotic apoptosis'. J. Cell. Mol. Med. 5, 240-253 (2001).
39. 99mTechnetium-MIBI in human peripheral blood lymphocytes: ex vivo study using micronucleus/FISH assay. Cancer Lett. 233, 68-78 (2006).
40. C. N. Sprung, M. Chao, T. Leong and M. J. McKay, Chromosomal radiosensitivity in two cell lineages derived from clinically radiosensitive cancer patients. Clin. Cancer Res. 11, 6352-6358 (2005).
41. E. H. Kajioka, M. L. Andres, J. Li, X. W. Mao, M. F. Moyers, G. A. Nelson, J. M. Slater and D. S. Gridley, Acute effects of whole-body proton irradiation on the immune system of the mouse. Radiat. Res. 153, 587-594 (2000).
42. H. R. Park, S. K. Jo and S. G. Paik, Factors effecting the Th2-like immune response after gamma-irradiation: low production of IL-12 heterodimer in antigen-presenting cells and small expression of the IL-12 receptor in T cells. Int. J. Radiat. Biol. 81, 221-231 (2005).
43. A. Banz, C. Pontoux and M. Papiernik, Modulation of Fas-dependent apoptosis: a dynamic process controlling both the persistence and death of CD4 regulatory T cells and effector T cells. J. Immunol. 169, 750-757 (2002).
44. - T cells to dexamethasone-induced cell death. Eur. J. Immunol. 34, 859-869 (2004).
45. J. Shimizu, S. Yamazaki, T. Takahashi, Y. Ishida and S. Sakaguchi, Stimulation of CD25(z)CD4(z) regulatory T cells through GITR breaks immunological self-tolerance. Nat. Immunol. 3, 135-142 (2002).
46. z naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162, 5317-5326 (1999).
47. F. Ghiringhelli, C. Menard, F. Martin and L. Zitvogel, The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression. Immunol. Rev. 214, 229-238 (2006).
48. z effector T cells during ocular herpes infection. J. Virol. 81, 7647-7661 (2007).
49. Y. Zhao and G. Liu, Specific immune tolerance of antigen-presenting cells: Hypothesis and significance. Med. Hypoth. 68, 404-406 (2007).