Dose and dose rate effects of whole-body γ-irradiation: I. lymphocytes and lymphoid organs

In Vivo

Volumn 15, Issue 3, 2001, Pages 195-208

  Pecaut, M J ^a   Nelson, G A ^a   Gridley, D S ^a  

^a LOMA LINDA UNIVERSITY   (United States)

Author keywords

B cells; Gamma rays; NK cells; Spleen; T cells; Thymus

Indexed keywords

CD19 ANTIGEN; CD3 ANTIGEN; CD8 ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BLOOD; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GAMMA IRRADIATION; HELPER CELL; IMMUNE RESPONSE; LEUKOCYTE COUNT; LYMPHOCYTE; LYMPHOCYTE COUNT; LYMPHOID ORGAN; MOUSE; NATURAL KILLER CELL; NONHUMAN; RADIATION BEAM; RADIATION DEPTH DOSE; RADIATION DOSE; RADIATION EXPOSURE; SPLEEN SIZE; T LYMPHOCYTE; THYMUS; WHOLE BODY RADIATION;

EID: 0034914520     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Rodent growth, behavior, and physiology resulting from flight on the space live sciences-1 mission
2. Weightlessness effects on resistance and reactivity of animals
3. Effects of space flight and PEG-IL-2 on rat physiological and immunological responses
4. Spaceflight and development of immune responses
5. Effect of SLS-2 spacelight on immunologic parameters of rats
6. Spaceflight alters immune cell function and distribution
7. Altered skeletal pattern of gene expression in response to spaceflight and hindlimb elevation
8. Effects of spaceflight on the number of rat peripheral blood leukocytes and lymphocyte subsets
9. Effects of spaceflight on rat peripheral blood leukocytes and bone marrow progenitor cells
10. Effects of spaceflight on levels and activity of immune cells
11. Spaceflight induces changes in splenocyte subpopulations: Effectiveness of ground-based models
12. Combined effects of space flight factors and radiation on humans
13. Temporal analysis of the October 1989 proton flare using computerized anatomical models
14. Biological effects and physics of solar and galactic cosmic radiation
15. Modification of immune response by low dose ionizing radiation: Role of apoptosis
16. Dose and dose-rate effects of whole-body γ-irradiation: II. Hematological variables and cytokines
17. Induction of the expression of the interleukin-1beta gene in mouse spleen by ionizing radiation
18. Mice chronically exposed to low dose ionizing radiation posses splenocytes with elevated levels of HSP70 mRNA, HSC70 and HSP72 and with an increased capacity of proliferate
19. DNA strand breaks and DNA repair response in lymphocytes after chronic in vivo exposure to very low doses of ionizing radiation in mice
20. Radiation damage and immune suppression in splenic mononuclear cell populations
21. The radiosensitivity of T and B lymphocytes in mice
22. Ionizing radiation and the immune response
23. Relative alterations in blood mononuclear cell populations reflect radiation injury in mice
24. Effects of radiation on survival and recovery of T lymphocyte subsets in C3H/HeN mice
25. Acute effects of whole-body proton irradiation on the immune system of the mouse
26. Effects of gypenosides in cellular immunity of γ-ray-irradiated mice
27. Effect of oleanolic acid and ursolic acid on inhibiting tumor growth and enhancing the recovery of hematopoietic system postirradiation in mice
28. Effects of glycyrrhizae and glycyrrhizic acid on cellular immunocompetence of γ-ray-irradiated mice
29. Immune potentiation after fractionated exposure to very low doses of ionizing radiation and/or caloric restriction in autoimmune-prone and normal C57BL/6 Mice
30. Selective radiation resistance of immunologically induced T-cells as the basis for irradiatin-induced T-cell-mediated regressin of immunogenic tumor
31. T cell potentiation in normal and autoimmune-prone mice after extended exposure to low dose of ionizing radiation and/or caloric restriction
32. Differential effect of L3T4+ cells on recovery from total-body irradiation
33. Regulation of hematopoiesis: Helper and suppressor influences of the thymus
34. Effect of radiation and 4-hydroperoxycyclophosphamide on thymic regulators of erythropoietic growth
35. T-Cell repopulation from functionally restricted splenic progenitors: 10,000-fold expansion documented by limited dilution analysis
36. Adaptation of cell renewal systems under continuous irradiation
37. Chapter 5: The role of the spleen in lymphocyte migration
38. Homing receptor and the control of lymphocyte migration
39. Heterogenety of lymphoyte homing physiology: Several mechanisms operate in the control of migration to lymphoid and non-lymphoid organs in vivo
40. Lymphocyte homing and homeostasis
41. Cell adhesion molecules mediate radiation-induced leukocyte adhesion to vascular endothelium
42. Invesigation of space flight effects on Escherichia coli and a proposed model of underlying physical mechanisms
43. Behavior of bacteria and antibiotics under space conditions