Intended transcriptional silencing with siRNA results in gene repression through sequence-specific off-targeting

RNA

Volumn 16, Issue 2, 2010, Pages 430-441

  Moses, Joshua ^a   Goodchild, Amber ^b   Rivory, Laurent P ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b ELI LILLY AUSTRALIA PTY LTD   (Australia)

Author keywords

Off target silencing; Promoter specific siRNA; RNA interference; Transcriptional gene silencing

Indexed keywords

LUCIFERASE; SMALL INTERFERING RNA; VASCULOTROPIN;

ARTICLE; CONTROLLED STUDY; GENE CONTROL; GENE REPRESSION; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; RNA INTERFERENCE; RNA SEQUENCE; TRANSCRIPTION REGULATION; VIRUS STRAIN;

BASE SEQUENCE; CELL LINE; COMPUTATIONAL BIOLOGY; GENE SILENCING; GENES, REPORTER; HELA CELLS; HIV LONG TERMINAL REPEAT; HUMANS; LUCIFERASES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLASMIDS; PROMOTER REGIONS, GENETIC; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 75149128655     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.1808510     Document Type: Article

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