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Volumn 298, Issue 2, 2010, Pages

Influence of glucosamine on glomerular mesangial cell turnover: Implications for hyperglycemia and hexosamine pathway flux

Author keywords

Cell turnover; Hexosamine flux; High glucose

Indexed keywords

6 DIAZO 5 OXONORLEUCINE; 6 PHOSPHOFRUCTOKINASE; CYCLINE; GLUCOSAMINE; GLUCOSE; GLUTAMINE FRUCTOSE 6 PHOPHATE AMIDOTRANSFERASE; HEXOSAMINE; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; UNCLASSIFIED DRUG;

EID: 74949118965     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00232.2009     Document Type: Article
Times cited : (13)

References (72)
  • 1
    • 34250619165 scopus 로고    scopus 로고
    • The mammalian target of rapamycin signaling pathway: Twists and turns in the road to cancer therapy
    • Abraham RT, Gibbons JJ. The mammalian target of rapamycin signaling pathway: twists and turns in the road to cancer therapy. Clin Cancer Res 13: 3109-3114, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 3109-3114
    • Abraham, R.T.1    Gibbons, J.J.2
  • 2
    • 29244441713 scopus 로고    scopus 로고
    • Biphasic effect of p21Cip1 on smooth muscle cell proliferation: Role of PI 3-kinase and Skp2-mediated degradation
    • Bond M, Sala-Newby GB, Wu YJ, Newby AC. Biphasic effect of p21Cip1 on smooth muscle cell proliferation: role of PI 3-kinase and Skp2-mediated degradation. Cardiovasc Res 69: 198-206, 2006.
    • (2006) Cardiovasc Res , vol.69 , pp. 198-206
    • Bond, M.1    Sala-Newby, G.B.2    Wu, Y.J.3    Newby, A.C.4
  • 3
    • 33846317766 scopus 로고    scopus 로고
    • Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein-associated O-GlcNAc
    • Champattanachai V, Marchase RB, Chatham JC. Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein-associated O-GlcNAc. Am J Physiol Cell Physiol 292: C178-C187, 2007.
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Champattanachai, V.1    Marchase, R.B.2    Chatham, J.C.3
  • 4
    • 40949083086 scopus 로고    scopus 로고
    • Chatham JC, Not LG, Fulop N, Marchase RB. Hexosamine biosynthesis and protein O-glycosylation: the first line of defense against stress, ischemia, and trauma. Shock 29: 431-440, 2008.
    • Chatham JC, Not LG, Fulop N, Marchase RB. Hexosamine biosynthesis and protein O-glycosylation: the first line of defense against stress, ischemia, and trauma. Shock 29: 431-440, 2008.
  • 5
    • 0031434015 scopus 로고    scopus 로고
    • Effects of overexpression of glutamine:fructose-6-phosphate amidotransferase (GFAT) and glucosamine treatment on translocation of GLUT4 in rat adipose cells
    • Chen H, Ing BL, Robinson KA, Feagin AC, Buse MG, Quon MJ. Effects of overexpression of glutamine:fructose-6-phosphate amidotransferase (GFAT) and glucosamine treatment on translocation of GLUT4 in rat adipose cells. Mol Cell Endocrinol 135: 67-77, 1997.
    • (1997) Mol Cell Endocrinol , vol.135 , pp. 67-77
    • Chen, H.1    Ing, B.L.2    Robinson, K.A.3    Feagin, A.C.4    Buse, M.G.5    Quon, M.J.6
  • 6
    • 21844468767 scopus 로고    scopus 로고
    • Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase
    • Chiang GG, Abraham RT. Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase. J Biol Chem 280: 25485-25490, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 25485-25490
    • Chiang, G.G.1    Abraham, R.T.2
  • 7
    • 35348820823 scopus 로고    scopus 로고
    • Targeting the mTOR signaling network in cancer
    • Chiang GG, Abraham RT. Targeting the mTOR signaling network in cancer. Trends Mol Med 13: 433-442, 2007.
    • (2007) Trends Mol Med , vol.13 , pp. 433-442
    • Chiang, G.G.1    Abraham, R.T.2
  • 8
    • 33745150087 scopus 로고    scopus 로고
    • The intricacies of p21 phosphorylation: Protein/protein interactions, subcellular localization and stability
    • Child ES, Mann DJ. The intricacies of p21 phosphorylation: protein/protein interactions, subcellular localization and stability. Cell Cycle 5: 1313-1319, 2006.
    • (2006) Cell Cycle , vol.5 , pp. 1313-1319
    • Child, E.S.1    Mann, D.J.2
  • 9
    • 0029035830 scopus 로고
    • Effects of high glucose concentrations on human mesangial cell proliferation
    • Cosio FG. Effects of high glucose concentrations on human mesangial cell proliferation. J Am Soc Nephrol 5: 1600-1609, 1995.
    • (1995) J Am Soc Nephrol , vol.5 , pp. 1600-1609
    • Cosio, F.G.1
  • 10
    • 0028951518 scopus 로고
    • Regulation of glycogen synthase by glucose, glucosamine, and glutamine:fructose-6-phosphate amidotransferase
    • Crook ED, Zhou J, Daniels M, Neidigh JL, McClain DA. Regulation of glycogen synthase by glucose, glucosamine, and glutamine:fructose-6-phosphate amidotransferase. Diabetes 44: 314-320, 1995.
    • (1995) Diabetes , vol.44 , pp. 314-320
    • Crook, E.D.1    Zhou, J.2    Daniels, M.3    Neidigh, J.L.4    McClain, D.A.5
  • 12
    • 0242671511 scopus 로고    scopus 로고
    • An antisense oligodeoxynucleotide to p21(Waf1/Cip1) causes apoptosis in human breast cancer cells
    • Fan Y, Borowsky AD, Weiss RH. An antisense oligodeoxynucleotide to p21(Waf1/Cip1) causes apoptosis in human breast cancer cells. Mol Cancer Ther 2: 773-782, 2003.
    • (2003) Mol Cancer Ther , vol.2 , pp. 773-782
    • Fan, Y.1    Borowsky, A.D.2    Weiss, R.H.3
  • 14
    • 20144384882 scopus 로고    scopus 로고
    • Lost in transcription: P21 repression, mechanisms, and consequences
    • Gartel AL, Radhakrishnan SK. Lost in transcription: p21 repression, mechanisms, and consequences. Cancer Res 65: 3980-3985, 2005.
    • (2005) Cancer Res , vol.65 , pp. 3980-3985
    • Gartel, A.L.1    Radhakrishnan, S.K.2
  • 15
    • 13844271825 scopus 로고    scopus 로고
    • Glomerular proliferation during early stages of diabetic nephropathy is associated with local increase of sphingosine-1-phosphate levels
    • Geoffroy K, Troncy L, Wiernsperger N, Lagarde M, El Bawab S. Glomerular proliferation during early stages of diabetic nephropathy is associated with local increase of sphingosine-1-phosphate levels. FEBS Lett 579: 1249-1254, 2005.
    • (2005) FEBS Lett , vol.579 , pp. 1249-1254
    • Geoffroy, K.1    Troncy, L.2    Wiernsperger, N.3    Lagarde, M.4    El Bawab, S.5
  • 16
    • 34347351282 scopus 로고    scopus 로고
    • Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest
    • Giono LE, Manfredi JJ. Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest. Mol Cell Biol 27: 4166-4178, 2007.
    • (2007) Mol Cell Biol , vol.27 , pp. 4166-4178
    • Giono, L.E.1    Manfredi, J.J.2
  • 17
    • 34247583996 scopus 로고    scopus 로고
    • Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins
    • Hart GW, Housley MP, Slawson C. Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins. Nature 446: 1017-1022, 2007.
    • (2007) Nature , vol.446 , pp. 1017-1022
    • Hart, G.W.1    Housley, M.P.2    Slawson, C.3
  • 18
    • 0025782244 scopus 로고
    • N-acetylglucosaminono-1,5- lactone oxime and the corresponding (phenylcarbamoyl)oxime. Novel and potent inhibitors of beta-N-acetylglucosaminidase
    • Horsch M, Hoesch L, Vasella A, Rast DM. N-acetylglucosaminono-1,5- lactone oxime and the corresponding (phenylcarbamoyl)oxime. Novel and potent inhibitors of beta-N-acetylglucosaminidase. Eur J Biochem 197: 815-818, 1991.
    • (1991) Eur J Biochem , vol.197 , pp. 815-818
    • Horsch, M.1    Hoesch, L.2    Vasella, A.3    Rast, D.M.4
  • 19
    • 58649095123 scopus 로고    scopus 로고
    • Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose
    • Hu Y, Suarez J, Fricovsky E, Wang H, Scott BT, Trauger SA, Han W, Hu Y, Oyeleye MO, Dillmann WH. Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose. J Biol Chem 284: 547-555, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 547-555
    • Hu, Y.1    Suarez, J.2    Fricovsky, E.3    Wang, H.4    Scott, B.T.5    Trauger, S.A.6    Han, W.7    Hu, Y.8    Oyeleye, M.O.9    Dillmann, W.H.10
  • 21
    • 0036231781 scopus 로고    scopus 로고
    • Flux through the hexosamine pathway is a determinant of nuclear factor kappaB-dependent promoter activation
    • James LR, Tang D, Ingram A, Ly H, Thai K, Cai L, Scholey JW. Flux through the hexosamine pathway is a determinant of nuclear factor kappaB-dependent promoter activation. Diabetes 51: 1146-1156, 2002.
    • (2002) Diabetes , vol.51 , pp. 1146-1156
    • James, L.R.1    Tang, D.2    Ingram, A.3    Ly, H.4    Thai, K.5    Cai, L.6    Scholey, J.W.7
  • 22
    • 0032989227 scopus 로고    scopus 로고
    • Effect of glucose on stress-activated protein kinase activity in mesangial cells and diabetic glomeruli
    • Kang MJ, Wu X, Ly H, Thai K, Scholey JW. Effect of glucose on stress-activated protein kinase activity in mesangial cells and diabetic glomeruli. Kidney Int 55: 2203-2214, 1999.
    • (1999) Kidney Int , vol.55 , pp. 2203-2214
    • Kang, M.J.1    Wu, X.2    Ly, H.3    Thai, K.4    Scholey, J.W.5
  • 24
    • 0031975643 scopus 로고    scopus 로고
    • High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells
    • Kolm-Litty V, Sauer U, Nerlich A, Lehmann R, Schleicher ED. High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells. J Clin Invest 101: 160-169, 1998.
    • (1998) J Clin Invest , vol.101 , pp. 160-169
    • Kolm-Litty, V.1    Sauer, U.2    Nerlich, A.3    Lehmann, R.4    Schleicher, E.D.5
  • 27
    • 0033552595 scopus 로고    scopus 로고
    • Regulation of p53 in response to DNA damage
    • Lakin ND, Jackson SP. Regulation of p53 in response to DNA damage. Oncogene 18: 7644-7655, 1999.
    • (1999) Oncogene , vol.18 , pp. 7644-7655
    • Lakin, N.D.1    Jackson, S.P.2
  • 28
    • 29144501653 scopus 로고    scopus 로고
    • Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts
    • Leach CA, Michael WM. Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts. J Cell Biol 171: 947-954, 2005.
    • (2005) J Cell Biol , vol.171 , pp. 947-954
    • Leach, C.A.1    Michael, W.M.2
  • 30
    • 33749251120 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling modulates survival of high glucose-stressed mesangial cells
    • Lin CL, Wang JY, Huang YT, Kuo YH, Surendran K, Wang FS. Wnt/beta-catenin signaling modulates survival of high glucose-stressed mesangial cells. J Am Soc Nephrol 17: 2812-2820, 2006.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2812-2820
    • Lin, C.L.1    Wang, J.Y.2    Huang, Y.T.3    Kuo, Y.H.4    Surendran, K.5    Wang, F.S.6
  • 31
    • 0034646330 scopus 로고    scopus 로고
    • Glucose stimulates protein modification by O-linked GlcNAc in pancreatic beta cells: Linkage of O-linked GlcNAc to beta cell death
    • Liu K, Paterson AJ, Chin E, Kudlow JE. Glucose stimulates protein modification by O-linked GlcNAc in pancreatic beta cells: linkage of O-linked GlcNAc to beta cell death. Proc Natl Acad Sci USA 97: 2820-2825, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2820-2825
    • Liu, K.1    Paterson, A.J.2    Chin, E.3    Kudlow, J.E.4
  • 34
  • 35
    • 0025855139 scopus 로고
    • Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance
    • Marshall S, Bacote V, Traxinger RR. Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance. J Biol Chem 266: 4706-4712, 1991.
    • (1991) J Biol Chem , vol.266 , pp. 4706-4712
    • Marshall, S.1    Bacote, V.2    Traxinger, R.R.3
  • 36
    • 4143074732 scopus 로고    scopus 로고
    • Dynamic actions of glucose and glucosamine on hexosamine biosynthesis in isolated adipocytes: Differential effects on glucosamine 6-phosphate, UDP-N-acetylglucosamine, and ATP levels
    • Marshall S, Nadeau O, Yamasaki K. Dynamic actions of glucose and glucosamine on hexosamine biosynthesis in isolated adipocytes: differential effects on glucosamine 6-phosphate, UDP-N-acetylglucosamine, and ATP levels. J Biol Chem 279: 35313-35319, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 35313-35319
    • Marshall, S.1    Nadeau, O.2    Yamasaki, K.3
  • 37
    • 20544441287 scopus 로고    scopus 로고
    • Glucosamine induces cell-cycle arrest and hypertrophy of mesangial cells: Implication of gangliosides
    • Masson E, Wiernsperger N, Lagarde M, El Bawab S. Glucosamine induces cell-cycle arrest and hypertrophy of mesangial cells: implication of gangliosides. Biochem J 388: 537-544, 2005.
    • (2005) Biochem J , vol.388 , pp. 537-544
    • Masson, E.1    Wiernsperger, N.2    Lagarde, M.3    El Bawab, S.4
  • 38
    • 0032710966 scopus 로고    scopus 로고
    • Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuria
    • Meyer TW, Bennett PH, Nelson RG. Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuria. Diabetologia 42: 1341-1344, 1999.
    • (1999) Diabetologia , vol.42 , pp. 1341-1344
    • Meyer, T.W.1    Bennett, P.H.2    Nelson, R.G.3
  • 39
    • 10944263493 scopus 로고    scopus 로고
    • High glucose evokes an intrinsic proapoptotic signaling pathway in mesangial cells
    • Mishra R, Emancipator SN, Kern T, Simonson MS. High glucose evokes an intrinsic proapoptotic signaling pathway in mesangial cells. Kidney Int 67: 82-93, 2005.
    • (2005) Kidney Int , vol.67 , pp. 82-93
    • Mishra, R.1    Emancipator, S.N.2    Kern, T.3    Simonson, M.S.4
  • 40
    • 34249066085 scopus 로고    scopus 로고
    • PCNA, the maestro of the replication fork
    • Moldovan GL, Pfander B, Jentsch S. PCNA, the maestro of the replication fork. Cell 129: 665-679, 2007.
    • (2007) Cell , vol.129 , pp. 665-679
    • Moldovan, G.L.1    Pfander, B.2    Jentsch, S.3
  • 41
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63, 1983.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 43
    • 2442431498 scopus 로고    scopus 로고
    • The post-translational modifications of proliferating cell nuclear antigen: Acetylation, not phosphorylation, plays an important role in the regulation of its function
    • Naryzhny SN, Lee H. The post-translational modifications of proliferating cell nuclear antigen: acetylation, not phosphorylation, plays an important role in the regulation of its function. J Biol Chem 279: 20194-20199, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 20194-20199
    • Naryzhny, S.N.1    Lee, H.2
  • 44
    • 0030953450 scopus 로고    scopus 로고
    • Clinical and pathological course of renal disease in non-insulin-dependent diabetes mellitus: The Pima Indian experience
    • Nelson RG, Meyer TW, Myers BD, Bennett PH. Clinical and pathological course of renal disease in non-insulin-dependent diabetes mellitus: the Pima Indian experience. Semin Nephrol 17: 124-131, 1997.
    • (1997) Semin Nephrol , vol.17 , pp. 124-131
    • Nelson, R.G.1    Meyer, T.W.2    Myers, B.D.3    Bennett, P.H.4
  • 45
    • 0031938518 scopus 로고    scopus 로고
    • Expression of glutamine:fructose-6-phosphate amidotransferase in human tissues: Evidence for high variability and distinct regulation in diabetes
    • Nerlich AG, Sauer U, Kolm-Litty V, Wagner E, Koch M, Schleicher ED. Expression of glutamine:fructose-6-phosphate amidotransferase in human tissues: evidence for high variability and distinct regulation in diabetes. Diabetes 47: 170-178, 1998.
    • (1998) Diabetes , vol.47 , pp. 170-178
    • Nerlich, A.G.1    Sauer, U.2    Kolm-Litty, V.3    Wagner, E.4    Koch, M.5    Schleicher, E.D.6
  • 46
    • 0033917703 scopus 로고    scopus 로고
    • Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure
    • Ortiz A, Lorz C, Catalan MP, Danoff TM, Yamasaki Y, Egido J, Neilson EG. Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure. Kidney Int 57: 969-981, 2000.
    • (2000) Kidney Int , vol.57 , pp. 969-981
    • Ortiz, A.1    Lorz, C.2    Catalan, M.P.3    Danoff, T.M.4    Yamasaki, Y.5    Egido, J.6    Neilson, E.G.7
  • 47
    • 0031062401 scopus 로고    scopus 로고
    • Expression of apoptosis-regulatory genes in renal proximal tubular epithelial cells exposed to high ambient glucose and in diabetic kidneys
    • Ortiz A, Ziyadeh FN, Neilson EG. Expression of apoptosis-regulatory genes in renal proximal tubular epithelial cells exposed to high ambient glucose and in diabetic kidneys. J Investig Med 45: 50-56, 1997.
    • (1997) J Investig Med , vol.45 , pp. 50-56
    • Ortiz, A.1    Ziyadeh, F.N.2    Neilson, E.G.3
  • 49
    • 0015589845 scopus 로고
    • Transport and metabolism of glucosamine by cultured Novikoff rat hepatoma cells and effects on nucleotide pools
    • Plagemann PG, Erbe J. Transport and metabolism of glucosamine by cultured Novikoff rat hepatoma cells and effects on nucleotide pools. Cancer Res 33: 482-492, 1973.
    • (1973) Cancer Res , vol.33 , pp. 482-492
    • Plagemann, P.G.1    Erbe, J.2
  • 50
    • 0032521004 scopus 로고    scopus 로고
    • Lysophosphatidic acid-mediated signal-transduction pathways involved in the induction of the early-response genes prostaglandin G/H synthase-2 and Egr-1: A critical role for the mitogen-activated protein kinase p38 and for Rho proteins
    • Reiser CO, Lanz T, Hofmann F, Hofer G, Rupprecht HD, Goppelt-Struebe M. Lysophosphatidic acid-mediated signal-transduction pathways involved in the induction of the early-response genes prostaglandin G/H synthase-2 and Egr-1: a critical role for the mitogen-activated protein kinase p38 and for Rho proteins. Biochem J 330: 1107-1114, 1998.
    • (1998) Biochem J , vol.330 , pp. 1107-1114
    • Reiser, C.O.1    Lanz, T.2    Hofmann, F.3    Hofer, G.4    Rupprecht, H.D.5    Goppelt-Struebe, M.6
  • 51
    • 0037123438 scopus 로고    scopus 로고
    • Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load
    • Reynolds TH, Bodine SC, Lawrence JC Jr. Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load. J Biol Chem 277: 17657-17662, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 17657-17662
    • Reynolds, T.H.1    Bodine, S.C.2    Lawrence Jr., J.C.3
  • 52
    • 0030789576 scopus 로고    scopus 로고
    • Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis
    • Sandau K, Pfeilschifter J, Brune B. Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis. Kidney Int 52: 378-386, 1997.
    • (1997) Kidney Int , vol.52 , pp. 378-386
    • Sandau, K.1    Pfeilschifter, J.2    Brune, B.3
  • 53
    • 17544379257 scopus 로고    scopus 로고
    • Glucose metabolism to glucosamine is necessary for glucose stimulation of transforming growth factor-alpha gene transcription
    • Sayeski PP, Kudlow JE. Glucose metabolism to glucosamine is necessary for glucose stimulation of transforming growth factor-alpha gene transcription. J Biol Chem 271: 15237-15243, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 15237-15243
    • Sayeski, P.P.1    Kudlow, J.E.2
  • 54
    • 33846892487 scopus 로고    scopus 로고
    • Homocysteine induces mesangial cell apoptosis via activation of p38-mitogen-activated protein kinase
    • Shastry S, Ingram AJ, Scholey JW, James LR. Homocysteine induces mesangial cell apoptosis via activation of p38-mitogen-activated protein kinase. Kidney Int 71: 304-311, 2007.
    • (2007) Kidney Int , vol.71 , pp. 304-311
    • Shastry, S.1    Ingram, A.J.2    Scholey, J.W.3    James, L.R.4
  • 55
    • 0033961443 scopus 로고    scopus 로고
    • Role of p53 family members in apoptosis
    • Sheikh MS, Fornace AJ Jr. Role of p53 family members in apoptosis. J Cell Physiol 182: 171-181, 2000.
    • (2000) J Cell Physiol , vol.182 , pp. 171-181
    • Sheikh, M.S.1    Fornace Jr, A.J.2
  • 56
    • 3042530936 scopus 로고    scopus 로고
    • Activation of phosphoinositide 3-kinase in response to high glucose leads to regulation of reactive oxygen species-related nuclear factor-kappaB activation and cyclooxygenase-2 expression in mesangial cells
    • Sheu ML, Ho FM, Chao KF, Kuo ML, Liu SH. Activation of phosphoinositide 3-kinase in response to high glucose leads to regulation of reactive oxygen species-related nuclear factor-kappaB activation and cyclooxygenase-2 expression in mesangial cells. Mol Pharmacol 66: 187-196, 2004.
    • (2004) Mol Pharmacol , vol.66 , pp. 187-196
    • Sheu, M.L.1    Ho, F.M.2    Chao, K.F.3    Kuo, M.L.4    Liu, S.H.5
  • 57
    • 34548802931 scopus 로고    scopus 로고
    • Hexosamine induction of oxidative stress, hypertrophy and laminin expression in renal mesangial cells: Effect of the anti-oxidant alpha-lipoic acid
    • Singh LP, Cheng DW, Kowluru R, Levi E, Jiang Y. Hexosamine induction of oxidative stress, hypertrophy and laminin expression in renal mesangial cells: effect of the anti-oxidant alpha-lipoic acid. Cell Biochem Funct 25: 537-550, 2006.
    • (2006) Cell Biochem Funct , vol.25 , pp. 537-550
    • Singh, L.P.1    Cheng, D.W.2    Kowluru, R.3    Levi, E.4    Jiang, Y.5
  • 58
    • 30044438532 scopus 로고    scopus 로고
    • O-GlcNAc cycling: How a single sugar post-translational modification is changing the way we think about signaling networks
    • Slawson C, Housley MP, Hart GW. O-GlcNAc cycling: how a single sugar post-translational modification is changing the way we think about signaling networks. J Cell Biochem 97: 71-83, 2006.
    • (2006) J Cell Biochem , vol.97 , pp. 71-83
    • Slawson, C.1    Housley, M.P.2    Hart, G.W.3
  • 59
    • 57349187712 scopus 로고    scopus 로고
    • A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin
    • Slawson C, Lakshmanan T, Knapp S, Hart GW. A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin. Mol Biol Cell 19: 4130-4140, 2008.
    • (2008) Mol Biol Cell , vol.19 , pp. 4130-4140
    • Slawson, C.1    Lakshmanan, T.2    Knapp, S.3    Hart, G.W.4
  • 60
    • 25444501339 scopus 로고    scopus 로고
    • Perturbations in O-linked beta-N-acetylglucosamine protein modification cause severe defects in mitotic progression and cytokinesis
    • Slawson C, Zachara NE, Vosseller K, Cheung WD, Lane MD, Hart GW. Perturbations in O-linked beta-N-acetylglucosamine protein modification cause severe defects in mitotic progression and cytokinesis. J Biol Chem 280: 32944-32956, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 32944-32956
    • Slawson, C.1    Zachara, N.E.2    Vosseller, K.3    Cheung, W.D.4    Lane, M.D.5    Hart, G.W.6
  • 61
    • 33644783770 scopus 로고    scopus 로고
    • Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy
    • Susztak K, Raff AC, Schiffer M, Bottinger EP. Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes 55: 225-233, 2006.
    • (2006) Diabetes , vol.55 , pp. 225-233
    • Susztak, K.1    Raff, A.C.2    Schiffer, M.3    Bottinger, E.P.4
  • 62
    • 58049216350 scopus 로고    scopus 로고
    • Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2
    • Toschi A, Lee E, Gadir N, Ohh M, Foster DA. Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2. J Biol Chem 283: 34495-34499, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 34495-34499
    • Toschi, A.1    Lee, E.2    Gadir, N.3    Ohh, M.4    Foster, D.A.5
  • 63
    • 62849111751 scopus 로고    scopus 로고
    • Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: Competition with rapamycin
    • Toschi A, Lee E, Xu L, Garcia A, Gadir N, Foster DA. Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin. Mol Cell Biol 29: 1411-1420, 2009.
    • (2009) Mol Cell Biol , vol.29 , pp. 1411-1420
    • Toschi, A.1    Lee, E.2    Xu, L.3    Garcia, A.4    Gadir, N.5    Foster, D.A.6
  • 65
    • 0033864452 scopus 로고    scopus 로고
    • Cell cycle regulation in diabetic nephropathy
    • Wolf G. Cell cycle regulation in diabetic nephropathy. Kidney Int Suppl 77: S59-S66, 2000.
    • (2000) Kidney Int Suppl , vol.77
    • Wolf, G.1
  • 66
    • 0026787630 scopus 로고
    • High glucoseinduced proliferation in mesangial cells is reversed by autocrine TGF-beta
    • Wolf G, Sharma K, Chen Y, Ericksen M, Ziyadeh FN. High glucoseinduced proliferation in mesangial cells is reversed by autocrine TGF-beta. Kidney Int 42: 647-656, 1992.
    • (1992) Kidney Int , vol.42 , pp. 647-656
    • Wolf, G.1    Sharma, K.2    Chen, Y.3    Ericksen, M.4    Ziyadeh, F.N.5
  • 67
    • 34748880045 scopus 로고    scopus 로고
    • Rapamycin prevents early steps of the development of diabetic nephropathy in rats
    • Yang Y, Wang J, Qin L, Shou Z, Zhao J, Wang H, Chen Y, Chen J. Rapamycin prevents early steps of the development of diabetic nephropathy in rats. Am J Nephrol 27: 495-502, 2007.
    • (2007) Am J Nephrol , vol.27 , pp. 495-502
    • Yang, Y.1    Wang, J.2    Qin, L.3    Shou, Z.4    Zhao, J.5    Wang, H.6    Chen, Y.7    Chen, J.8
  • 72
    • 33847665035 scopus 로고    scopus 로고
    • Phenotype-specific inhibition of the vascular smooth muscle cell cycle by high glucose treatment
    • Zheng XL, Yuan SG, Peng DQ. Phenotype-specific inhibition of the vascular smooth muscle cell cycle by high glucose treatment. Diabetologia 50: 881-890, 2007.
    • (2007) Diabetologia , vol.50 , pp. 881-890
    • Zheng, X.L.1    Yuan, S.G.2    Peng, D.Q.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.