Activation of phosphoinositide 3-kinase in response to high glucose leads to regulation of reactive oxygen species-related nuclear factor-κB activation and cyclooxygenase-2 expression in mesangial cells

Molecular Pharmacology

Volumn 66, Issue 1, 2004, Pages 187-196

  Sheu, Meei Ling ^a   Ho, Feng Ming ^b   Chao, Kuo Fang ^a   Kuo, Ming Liang ^a   Liu, Shing Hwa ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CHUNGTAI INST HLTH SCI TECHNOL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ACETYLSALICYLIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; ATTENUATION; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETIC NEPHROPATHY; EARLY DIAGNOSIS; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME MECHANISM; EXPERIMENTAL DIABETES MELLITUS; EXTRACELLULAR MATRIX; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INHIBITION KINETICS; MALE; MESANGIUM; MESANGIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 1-PHOSPHATIDYLINOSITOL 4-KINASE; ANIMALS; CELLS, CULTURED; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ENZYME ACTIVATION; GENE EXPRESSION; GLOMERULAR MESANGIUM; GLUCOSE; ISOENZYMES; MALE; MEMBRANE PROTEINS; NF-KAPPA B; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 3042530936     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.66.1.187     Document Type: Article

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