-
1
-
-
0030908042
-
Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase in endothelial cells
-
Abedi H, Zachary I. 1997. Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase in endothelial cells. J Biol Chem 272:15442-15451.
-
(1997)
J Biol Chem
, vol.272
, pp. 15442-15451
-
-
Abedi, H.1
Zachary, I.2
-
2
-
-
0028884033
-
PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo
-
Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. 1995. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo. J Biol Chem 270:27489-27494.
-
(1995)
J Biol Chem
, vol.270
, pp. 27489-27494
-
-
Alessi, D.R.1
Cuenda, A.2
Cohen, P.3
Dudley, D.T.4
Saltiel, A.R.5
-
3
-
-
0028152517
-
Regulation by insulin of phosphatidylinositol 3′-kinase bound to alphaand beta-isoforms of p85 regulatory subunit
-
Baltenaperger K, Kozma LM, Jaspers SR, Czech MP. 1994. Regulation by insulin of phosphatidylinositol 3′-kinase bound to alphaand beta-isoforms of p85 regulatory subunit. J Biol Chem 269: 28937-28946.
-
(1994)
J Biol Chem
, vol.269
, pp. 28937-28946
-
-
Baltenaperger, K.1
Kozma, L.M.2
Jaspers, S.R.3
Czech, M.P.4
-
4
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsentstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W, Nagy A. 1996. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380:435-438.
-
(1996)
Nature
, vol.380
, pp. 435-438
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsentstein, M.6
Fahrig, M.7
Vandenhoeck, A.8
Harpal, K.9
Eberhardt, C.10
Declercq, C.11
Pawling, J.12
Moons, L.13
Collen, D.14
Risau, W.15
Nagy, A.16
-
5
-
-
0025924683
-
Regulation of pp90rsk phosphorylation and S6 phosphotransferase activity in Swiss 3T3 cells by growth factor-, phorbol ester-, and cyclic AMP-mediated signal transduction
-
Chen RH. Chung JY, Blenis J. 1991. Regulation of pp90rsk phosphorylation and S6 phosphotransferase activity in Swiss 3T3 cells by growth factor-, phorbol ester-, and cyclic AMP-mediated signal transduction. Mol Cell Biol 11:1864-1867.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 1864-1867
-
-
Chen, R.H.1
Chung, J.Y.2
Blenis, J.3
-
6
-
-
0029890229
-
The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1
-
Chou MM, Blenis J. 1996. The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1. Cell 85:573-583.
-
(1996)
Cell
, vol.85
, pp. 573-583
-
-
Chou, M.M.1
Blenis, J.2
-
7
-
-
0026659046
-
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
-
Chung J, Kuo CJ, Crabtree GR, Blenis J. 1992. Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. Cell 69:1227-1236.
-
(1992)
Cell
, vol.69
, pp. 1227-1236
-
-
Chung, J.1
Kuo, C.J.2
Crabtree, G.R.3
Blenis, J.4
-
8
-
-
0028178928
-
PDGF-and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase
-
Chung J, Grammer TC, Lemon KP, Kazlauskas A, Blenis J. 1994. PDGF-and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase. Nature 370:71-75.
-
(1994)
Nature
, vol.370
, pp. 71-75
-
-
Chung, J.1
Grammer, T.C.2
Lemon, K.P.3
Kazlauskas, A.4
Blenis, J.5
-
9
-
-
0030565457
-
A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress
-
Clifton AD, Young PR, Cohen P. 1996. A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress. FEBS Lett 392:209-214.
-
(1996)
FEBS Lett
, vol.392
, pp. 209-214
-
-
Clifton, A.D.1
Young, P.R.2
Cohen, P.3
-
10
-
-
0029043582
-
How MAP kinases are regulated
-
Cobb MH, Goldsmith EJ. 1995. How MAP kinases are regulated. J Biol Chem 270:14843-14846.
-
(1995)
J Biol Chem
, vol.270
, pp. 14843-14846
-
-
Cobb, M.H.1
Goldsmith, E.J.2
-
11
-
-
0024461206
-
Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis
-
Connolly DT, Heuvelman DM, Nelson R, Olander JV, Eppley BL, Delfino JJ, Siegel NR, Leimgruber RM, Feder J. 1989. Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 84:1470-1478.
-
(1989)
J Clin Invest
, vol.84
, pp. 1470-1478
-
-
Connolly, D.T.1
Heuvelman, D.M.2
Nelson, R.3
Olander, J.V.4
Eppley, B.L.5
Delfino, J.J.6
Siegel, N.R.7
Leimgruber, R.M.8
Feder, J.9
-
12
-
-
0030037906
-
Interleukin-10 stimulation of phosphatidylinositol 3-kinase and p70 S6 kinase is required for the proliferative but not the antiinflammatory effects of the cytokine
-
Crawley JB, Williams LM, Mander T, Brennan FM, Foxwell MJ. 1996. Interleukin-10 stimulation of phosphatidylinositol 3-kinase and p70 S6 kinase is required for the proliferative but not the antiinflammatory effects of the cytokine. J Biol Chem 271:16357-16362.
-
(1996)
J Biol Chem
, vol.271
, pp. 16357-16362
-
-
Crawley, J.B.1
Williams, L.M.2
Mander, T.3
Brennan, F.M.4
Foxwell, M.J.5
-
13
-
-
0029047382
-
Interaction of the Fit-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding
-
Cunningham SA, Waxham MN, Arrate PM, Brock TA. 1995. Interaction of the Fit-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding. J Biol Chem 270:20254-20257.
-
(1995)
J Biol Chem
, vol.270
, pp. 20254-20257
-
-
Cunningham, S.A.1
Waxham, M.N.2
Arrate, P.M.3
Brock, T.A.4
-
14
-
-
0029973651
-
Studies of partially transforming polyomavirus mutants establish a role for phosphatidylinositol 3-kinase in activation of p70 S6 kinase
-
Dahl J, Freund R, Nlenis J, Benjamin TL. 1996. Studies of partially transforming polyomavirus mutants establish a role for phosphatidylinositol 3-kinase in activation of p70 S6 kinase. Mol Cell Biol 16:2728-2735.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2728-2735
-
-
Dahl, J.1
Freund, R.2
Nlenis, J.3
Benjamin, T.L.4
-
15
-
-
0029071065
-
Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the antiangiogenic factor 16-kDa N-terminal fragment of prolactin
-
D'Angelo G, Struman I, Martial J, Weiner RI. 1995. Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the antiangiogenic factor 16-kDa N-terminal fragment of prolactin. Proc Natl Acad Sci USA 92:6374-6378.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 6374-6378
-
-
D'Angelo, G.1
Struman, I.2
Martial, J.3
Weiner, R.I.4
-
16
-
-
0029828590
-
The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases
-
Dennis PB, Pullen N, Kozma SC, Thomas G. 1996. The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases. Mol Cell Biol 16:6242-6251.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6242-6251
-
-
Dennis, P.B.1
Pullen, N.2
Kozma, S.C.3
Thomas, G.4
-
17
-
-
0026572345
-
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
-
de Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT. 1992. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255:989-991.
-
(1992)
Science
, vol.255
, pp. 989-991
-
-
De Vries, C.1
Escobedo, J.A.2
Ueno, H.3
Houck, K.4
Ferrara, N.5
Williams, L.T.6
-
18
-
-
0032579532
-
Lipid-regulated kinases: Some common themes at last
-
Downward J. 1998. Lipid-regulated kinases: some common themes at last. Science 279:673-674.
-
(1998)
Science
, vol.279
, pp. 673-674
-
-
Downward, J.1
-
19
-
-
15844391440
-
Mechanism of action of the immunosuppressant rapamycin
-
Dumont FJ, Su Q. 1996. Mechanism of action of the immunosuppressant rapamycin. Life Sci 58:373-395.
-
(1996)
Life Sci
, vol.58
, pp. 373-395
-
-
Dumont, F.J.1
Su, Q.2
-
20
-
-
0025832626
-
Structure, expression, and regulation of protein kinases involved in the phosphorylation of ribosomal protein S6
-
Erikson RL. 1991. Structure, expression, and regulation of protein kinases involved in the phosphorylation of ribosomal protein S6. J Biol Chem 266:6007-6010.
-
(1991)
J Biol Chem
, vol.266
, pp. 6007-6010
-
-
Erikson, R.L.1
-
21
-
-
0026652899
-
Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways
-
Fantl WJ, Escobedo JA, Martin GA, Turck CW, del Rosario M, McCormick F, Williams LT. 1992. Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways. Cell 69:413-423.
-
(1992)
Cell
, vol.69
, pp. 413-423
-
-
Fantl, W.J.1
Escobedo, J.A.2
Martin, G.A.3
Turck, C.W.4
Del Rosario, M.5
McCormick, F.6
Williams, L.T.7
-
22
-
-
0031013368
-
Hemopoietic growth factors with the exception of interleukin-4 activate the p38 mitogenactivated protein kinase pathway
-
Foltz IN, Lee JC, Young PR, Schrader JW. 1997. Hemopoietic growth factors with the exception of interleukin-4 activate the p38 mitogenactivated protein kinase pathway. J Biol Chem 272:3296-3301.
-
(1997)
J Biol Chem
, vol.272
, pp. 3296-3301
-
-
Foltz, I.N.1
Lee, J.C.2
Young, P.R.3
Schrader, J.W.4
-
23
-
-
0028015872
-
Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27
-
Freshney NAV, Rawlinson L, Guesdon F, Jones E, Cowley S, Husan J, Saklatvala J. 1994. Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27. Cell 78:1039-1049.
-
(1994)
Cell
, vol.78
, pp. 1039-1049
-
-
Freshney, N.A.V.1
Rawlinson, L.2
Guesdon, F.3
Jones, E.4
Cowley, S.5
Husan, J.6
Saklatvala, J.7
-
24
-
-
0031056783
-
Regulation of actin filament dynamics by p38 MAP kinase-mediated phosphorylation of heat shock protein 27
-
Guay J, Lambert H, Gingras-Breton G, Lavoie JN, Huot J, Landry J. 1997. Regulation of actin filament dynamics by p38 MAP kinase-mediated phosphorylation of heat shock protein 27. J Cell Sci 110: 357-368.
-
(1997)
J Cell Sci
, vol.110
, pp. 357-368
-
-
Guay, J.1
Lambert, H.2
Gingras-Breton, G.3
Lavoie, J.N.4
Huot, J.5
Landry, J.6
-
25
-
-
0028899424
-
Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation
-
Guo D, Jia Q, Song H-Y, Warren RS, Donner DB. 1995. Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation. J Biol Chem 270:6729-6733.
-
(1995)
J Biol Chem
, vol.270
, pp. 6729-6733
-
-
Guo, D.1
Jia, Q.2
Song, H.-Y.3
Warren, R.S.4
Donner, D.B.5
-
26
-
-
0028905076
-
Transcription factor ATF2 regulation by the JNK signal transduction pathway
-
Gupta S, Campbell D, Derijard B, Davis RJ. 1995. Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267:389-393.
-
(1995)
Science
, vol.267
, pp. 389-393
-
-
Gupta, S.1
Campbell, D.2
Derijard, B.3
Davis, R.J.4
-
27
-
-
0027936755
-
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
-
Han J, Lee JD, Bibbs R, Ulevitch RJ. 1994. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265: 808-811.
-
(1994)
Science
, vol.265
, pp. 808-811
-
-
Han, J.1
Lee, J.D.2
Bibbs, R.3
Ulevitch, R.J.4
-
28
-
-
0029117423
-
Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl
-
Harley D, Meisner H, Corvera S. 1995. Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl. J Biol Chem 270:18260-18263.
-
(1995)
J Biol Chem
, vol.270
, pp. 18260-18263
-
-
Harley, D.1
Meisner, H.2
Corvera, S.3
-
29
-
-
0028897113
-
Transcriptional regulation by extracellular signals: Mechanisms and specificity
-
Hill CS, Treisman R. 1995. Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell 80:199-211.
-
(1995)
Cell
, vol.80
, pp. 199-211
-
-
Hill, C.S.1
Treisman, R.2
-
30
-
-
0021742144
-
Brain-and liver cell-derived factors are required for growth of human endothelial cells in serum-free culture
-
Hoshi H, McKeehan W. 1984. Brain-and liver cell-derived factors are required for growth of human endothelial cells in serum-free culture. Proc Natl Acad Sci U S A 81:6413-6417.
-
(1984)
Proc Natl Acad Sci U S A
, vol.81
, pp. 6413-6417
-
-
Hoshi, H.1
McKeehan, W.2
-
31
-
-
0027768579
-
Braking the cycles
-
Hunter T. 1993. Braking the cycles. Cell 75:839-841.
-
(1993)
Cell
, vol.75
, pp. 839-841
-
-
Hunter, T.1
-
32
-
-
0024801035
-
Vascular permeability factor, an endothelial cell mitogen related to PDGF
-
Keck PJ, Hauser SD, Krivi G, Sanzo K. Warren T, Feder J, Connolly DT. 1989. Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 246:1309-1312.
-
(1989)
Science
, vol.246
, pp. 1309-1312
-
-
Keck, P.J.1
Hauser, S.D.2
Krivi, G.3
Sanzo, K.4
Warren, T.5
Feder, J.6
Connolly, D.T.7
-
33
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo
-
Kim KJ , Li B, Winer J, Armanini M, Gillett N, Phillips HS, Ferrara N. 1993. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo. Nature 362:841-844.
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
Armanini, M.4
Gillett, N.5
Phillips, H.S.6
Ferrara, N.7
-
34
-
-
0028492138
-
p70s6k/p85s6k: Mechanism of activation and role in mitogenesis
-
Kozma SC, Thomas G. 1994. p70s6k/p85s6k: mechanism of activation and role in mitogenesis. Semin Cancer Biol 5:255-260.
-
(1994)
Semin Cancer Biol
, vol.5
, pp. 255-260
-
-
Kozma, S.C.1
Thomas, G.2
-
35
-
-
0031466232
-
The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells
-
Kroll J, Waltenberger J. 1997. The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells. J Biol Chem 272:32521-32527.
-
(1997)
J Biol Chem
, vol.272
, pp. 32521-32527
-
-
Kroll, J.1
Waltenberger, J.2
-
36
-
-
0028055272
-
Regulation of chemotaxis by the platelet-derived growth factor receptor-beta
-
Kundra V, Escobedo JA, Kazlauskas A, Kim HK, Rhee SG, Williams LT, Zetter BR. 1994. Regulation of chemotaxis by the platelet-derived growth factor receptor-beta. Nature 367:474-476.
-
(1994)
Nature
, vol.367
, pp. 474-476
-
-
Kundra, V.1
Escobedo, J.A.2
Kazlauskas, A.3
Kim, H.K.4
Rhee, S.G.5
Williams, L.T.6
Zetter, B.R.7
-
37
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
38
-
-
0028924759
-
Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27
-
Lavoie JN, Lambert H, Hickey E, Weber LA, Landry J. 1995. Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27. Mol Cell Biol 15:505-516.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 505-516
-
-
Lavoie, J.N.1
Lambert, H.2
Hickey, E.3
Weber, L.A.4
Landry, J.5
-
39
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, McNulty D, Blumenthal MJ, Heys JR, Landvatter SW. 1994. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372:739-746.
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
-
40
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. 1989. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246:1306-1309.
-
(1989)
Science
, vol.246
, pp. 1306-1309
-
-
Leung, D.W.1
Cachianes, G.2
Kuang, W.J.3
Goeddel, D.V.4
Ferrara, N.5
-
41
-
-
0030265327
-
Genes in the RB pathway and their knockout in mice
-
Lin SJ, Skapek SX, Lee EY. 1996. Genes in the RB pathway and their knockout in mice. Cancer Biol 7:279-289.
-
(1996)
Cancer Biol
, vol.7
, pp. 279-289
-
-
Lin, S.J.1
Skapek, S.X.2
Lee, E.Y.3
-
42
-
-
0029977949
-
Rapamycin resistance tied to defective regulation of p27Kip1
-
Luo Y, Marx SO, Kiyokawa H, Koff A, Massagué J, Marks AR. 1996. Rapamycin resistance tied to defective regulation of p27Kip1. Mol Cell Biol 16:6744-6751.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6744-6751
-
-
Luo, Y.1
Marx, S.O.2
Kiyokawa, H.3
Koff, A.4
Massagué, J.5
Marks, A.R.6
-
43
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall CJ. 1995. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179-185.
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
44
-
-
0025998533
-
A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit
-
Mathews W, Jordan CT, Gavin M, Jenkins NA, Copeland NG, Leimischka IR. 1991. A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. Proc Natl Acad Sci USA 88:9026-9030.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 9026-9030
-
-
Mathews, W.1
Jordan, C.T.2
Gavin, M.3
Jenkins, N.A.4
Copeland, N.G.5
Leimischka, I.R.6
-
45
-
-
0025991563
-
Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites
-
Myoken Y, Kayada Y, Okamoto T, Kan M, Sato GH, Sato JD. 1991. Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites. Proc Natl Acad Sci USA 88:5819-5823.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 5819-5823
-
-
Myoken, Y.1
Kayada, Y.2
Okamoto, T.3
Kan, M.4
Sato, G.H.5
Sato, J.D.6
-
46
-
-
0028359984
-
Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1)
-
Pages G, Brunet A, L'Allemain G, Pouysségur J. 1994. Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1). EMBO J 13:3003-3010.
-
(1994)
EMBO J
, vol.13
, pp. 3003-3010
-
-
Pages, G.1
Brunet, A.2
L'Allemain, G.3
Pouysségur, J.4
-
47
-
-
0025969093
-
Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase)
-
Payne DM, Rossomando AJ, Martino P, Erickson AK, Her JH, Shabanowitz J, Hunt DF, Weber MJ, Sturgill TW. 1991. Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase). EMBO J 10:885-892.
-
(1991)
EMBO J
, vol.10
, pp. 885-892
-
-
Payne, D.M.1
Rossomando, A.J.2
Martino, P.3
Erickson, A.K.4
Her, J.H.5
Shabanowitz, J.6
Hunt, D.F.7
Weber, M.J.8
Sturgill, T.W.9
-
48
-
-
0029078130
-
Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors
-
Petritsch C, Woscholski R, Edelmann HM, Parker PJ, Ballou LM. 1995. Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors. Eur J Biochem 230:431-438.
-
(1995)
Eur J Biochem
, vol.230
, pp. 431-438
-
-
Petritsch, C.1
Woscholski, R.2
Edelmann, H.M.3
Parker, P.J.4
Ballou, L.M.5
-
49
-
-
0031550222
-
p38 mitogen activated protein kinase regulates endothelial VCAM-1 expression at the post-transcriptional level
-
Pietersma A, Tilly BC, Gaestel M, de Jong N, Lee JC, Koster JF, Sluiter W. 1997. p38 mitogen activated protein kinase regulates endothelial VCAM-1 expression at the post-transcriptional level. Biochem Biophys Res Commun 230:44-48.
-
(1997)
Biochem Biophys Res Commun
, vol.230
, pp. 44-48
-
-
Pietersma, A.1
Tilly, B.C.2
Gaestel, M.3
De Jong, N.4
Lee, J.C.5
Koster, J.F.6
Sluiter, W.7
-
50
-
-
0032578998
-
Phosphorylation and activation of P70s6k by PDK1
-
Pullen N, Dennis PB, Andjelkovic M, Dufner A, Kozma SC, Hemmings BA, Thomas G. 1998. Phosphorylation and activation of P70s6k by PDK1. Science 279:707-710.
-
(1998)
Science
, vol.279
, pp. 707-710
-
-
Pullen, N.1
Dennis, P.B.2
Andjelkovic, M.3
Dufner, A.4
Kozma, S.C.5
Hemmings, B.A.6
Thomas, G.7
-
51
-
-
0026004501
-
Phosphorylation of c-jun mediated by MAP kinases
-
Pulverer BJ, Kyriakis JM, Avruch J, Nikolakaki E, Woodgett JR. 1991. Phosphorylation of c-jun mediated by MAP kinases. Nature 353:670-674.
-
(1991)
Nature
, vol.353
, pp. 670-674
-
-
Pulverer, B.J.1
Kyriakis, J.M.2
Avruch, J.3
Nikolakaki, E.4
Woodgett, J.R.5
-
52
-
-
0027249239
-
Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium
-
Quinn TP, Peters KG, De Vries C, Ferrara N, Williams LT. 1993. Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc Natl Acad Sci U S A 90:7533-7537.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 7533-7537
-
-
Quinn, T.P.1
Peters, K.G.2
De Vries, C.3
Ferrara, N.4
Williams, L.T.5
-
53
-
-
0028935270
-
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation of tyrosine and threonine
-
Raingeaud J, Gupta S, Rogers JS, Dickens M, Han J, Ulevitch RJ, Davis RJ. 1995. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation of tyrosine and threonine. J Biol Chem 270: 7420-7426.
-
(1995)
J Biol Chem
, vol.270
, pp. 7420-7426
-
-
Raingeaud, J.1
Gupta, S.2
Rogers, J.S.3
Dickens, M.4
Han, J.5
Ulevitch, R.J.6
Davis, R.J.7
-
54
-
-
0030952289
-
Mechanisms of angiogenesis
-
Risau W. 1997. Mechanisms of angiogenesis. Nature 386:671-674.
-
(1997)
Nature
, vol.386
, pp. 671-674
-
-
Risau, W.1
-
55
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana P, Warne PH, Dhand R, Vanhaesebroeck B, Gout I, Fry MJ, Waterfield MD, Downward J. 1994. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 370:527-532.
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.J.6
Waterfield, M.D.7
Downward, J.8
-
56
-
-
0028022750
-
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
-
Rouse J, Cohen P, Trigon S, Morange M, Alonso-Llamazares A, Zamanillo D, Hunt T, Nebreda AR. 1994. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 78:1027-1037.
-
(1994)
Cell
, vol.78
, pp. 1027-1037
-
-
Rouse, J.1
Cohen, P.2
Trigon, S.3
Morange, M.4
Alonso-Llamazares, A.5
Zamanillo, D.6
Hunt, T.7
Nebreda, A.R.8
-
57
-
-
0030734010
-
p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells
-
Rousseau S, Houle F, Landry F, Huot J. 1997. p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells. Oncogene 15:2169-2177.
-
(1997)
Oncogene
, vol.15
, pp. 2169-2177
-
-
Rousseau, S.1
Houle, F.2
Landry, F.3
Huot, J.4
-
58
-
-
0028798083
-
A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF
-
Seetharam L, Gotoh N, Maru Y, Neufeld G, Yamaguchi S, Shibuya M. 1995. A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF. Oncogene 10:135-147.
-
(1995)
Oncogene
, vol.10
, pp. 135-147
-
-
Seetharam, L.1
Gotoh, N.2
Maru, Y.3
Neufeld, G.4
Yamaguchi, S.5
Shibuya, M.6
-
59
-
-
0028171292
-
G1 phase progression: Cycling on cue
-
Sherr CJ. 1994. G1 phase progression: cycling on cue. Cell 79:551-555.
-
(1994)
Cell
, vol.79
, pp. 551-555
-
-
Sherr, C.J.1
-
60
-
-
0029071657
-
D-type cyclins
-
Sherr CJ. 1995. D-type cyclins. Trends Biochem Sci 20:187-190.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 187-190
-
-
Sherr, C.J.1
-
61
-
-
0029849620
-
Cancer cell cycles
-
Sherr CJ. 1996. Cancer cell cycles. Science 274:1672-1677.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
62
-
-
0026702970
-
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
-
Terman BI, Dougher-Vermazen M, Carrion ME, Dimitrov D, Armellino DC, Gospodarowicz D, Bohlen P. 1992. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun 187:1579-1586.
-
(1992)
Biochem Biophys Res Commun
, vol.187
, pp. 1579-1586
-
-
Terman, B.I.1
Dougher-Vermazen, M.2
Carrion, M.E.3
Dimitrov, D.4
Armellino, D.C.5
Gospodarowicz, D.6
Bohlen, P.7
-
63
-
-
0029118603
-
Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase
-
Ui M, Okada T, Hazeki K, Hazeki O. 1995. Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biochem Sci 20:303-307.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 303-307
-
-
Ui, M.1
Okada, T.2
Hazeki, K.3
Hazeki, O.4
-
64
-
-
0028170210
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
-
Vlahos CJ, Matter WF, Hui KY, Brown RF. 1994. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269:5241-5248.
-
(1994)
J Biol Chem
, vol.269
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
65
-
-
0021683002
-
Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein
-
Voyta JC, Via DP, Butterfield CE, Zetter BR. 1984. Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein. J Cell Biol 99:2034-2040.
-
(1984)
J Cell Biol
, vol.99
, pp. 2034-2040
-
-
Voyta, J.C.1
Via, D.P.2
Butterfield, C.E.3
Zetter, B.R.4
-
66
-
-
0027997863
-
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor
-
Waltenberger J, Claesson-Welsh L, Siegbahn A, Shibuya M, Heldin C-H. 1994. Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J Biol Chem 269:26988-26995.
-
(1994)
J Biol Chem
, vol.269
, pp. 26988-26995
-
-
Waltenberger, J.1
Claesson-Welsh, L.2
Siegbahn, A.3
Shibuya, M.4
Heldin, C.-H.5
-
67
-
-
0028429961
-
Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling
-
Wennström S, Hawkins P, Cooke F, Hara K, Yonezawa K, Kasuga M, Jackson T, Claesson-Welsh L, Stephens L. 1994. Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling. Curr Biol 4:385-393.
-
(1994)
Curr Biol
, vol.4
, pp. 385-393
-
-
Wennström, S.1
Hawkins, P.2
Cooke, F.3
Hara, K.4
Yonezawa, K.5
Kasuga, M.6
Jackson, T.7
Claesson-Welsh, L.8
Stephens, L.9
-
68
-
-
0021828496
-
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation
-
Whitman M, Kaplan DR, Schaffhausen B, Cantley L, Roberts TM. 1985. Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature 315:239-242.
-
(1985)
Nature
, vol.315
, pp. 239-242
-
-
Whitman, M.1
Kaplan, D.R.2
Schaffhausen, B.3
Cantley, L.4
Roberts, T.M.5
-
69
-
-
0030924833
-
Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site
-
Young PR, McLaughlin MM, Kumar S, Kassis S, Doyle ML, McNulty D, Gallagher TF, Fisher S, MaDonnell PC, Carr SA, Huddleston MJ, Seibel G, Porter TG, Livi GP, Adams JL, Lee JC. 1997. Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site. J Biol Chem 272:12116-12121.
-
(1997)
J Biol Chem
, vol.272
, pp. 12116-12121
-
-
Young, P.R.1
McLaughlin, M.M.2
Kumar, S.3
Kassis, S.4
Doyle, M.L.5
McNulty, D.6
Gallagher, T.F.7
Fisher, S.8
Madonnell, P.C.9
Carr, S.A.10
Huddleston, M.J.11
Seibel, G.12
Porter, T.G.13
Livi, G.P.14
Adams, J.L.15
Lee, J.C.16
-
70
-
-
0030977398
-
Mitogenactivated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells. Indications of communication between p38 and p42 MAP kinases
-
Zhang C, Baumgartner RA, Yamada K, Beaven MA. 1997. Mitogenactivated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells. Indications of communication between p38 and p42 MAP kinases. J Biol Chem 272:13397-13402.
-
(1997)
J Biol Chem
, vol.272
, pp. 13397-13402
-
-
Zhang, C.1
Baumgartner, R.A.2
Yamada, K.3
Beaven, M.A.4
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