The natural killer cell: A further innate mediator of gouty inflammation

Immunology and Cell Biology

Volumn 88, Issue 1, 2010, Pages 24-31

  Empson, Victoria G ^a   McQueen, Fiona M ^a   Dalbeth, Nicola ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Arthritis; Gout; Innate immunity; Macrophage; NK cell

Indexed keywords

CD56 ANTIGEN; NATURAL KILLER CELL RECEPTOR;

ADAPTIVE IMMUNITY; CELL INTERACTION; CELL STRESS; CELLULAR DISTRIBUTION; CYTOKINE PRODUCTION; CYTOTOXICITY; DENDRITIC CELL; EFFECTOR CELL; GOUT; HOMEOSTASIS; HUMAN; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; INNATE IMMUNITY; LYMPHOCYTE SUBPOPULATION; LYMPHOID ORGAN; MACROPHAGE; MONOCYTE; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; STEADY STATE; T LYMPHOCYTE; ANIMAL; IMMUNOLOGY; INFLAMMATION;

ADAPTIVE IMMUNITY; ANIMALS; GOUT; HUMANS; IMMUNITY, INNATE; INFLAMMATION; KILLER CELLS, NATURAL; RECEPTORS, NATURAL KILLER CELL;

EID: 74249109160     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2009.91     Document Type: Review

References (156)

1. Timonen T, Saksela E. Isolation of human NK cells by density gradient centrifugation. J Immunol Methods 1980; 36: 285.
2. Zhang Y, Wallace DL, de Lara CM, Ghattas H, Asquith B, Worth A et al. In vivo kinetics of human natural killer cells: the effects of ageing and acute and chronic viral infection. Immunology 2007; 121: 258.
3. Kumar V, Ben-Ezra J, Bennett M, Sonnenfeld G. Natural killer cells in mice treated with 89strontium: normal target-binding cell numbers but inability to kill even after interferon administration. J Immunol 1979; 123: 1832-1838.
4. Seaman WE, Gindhart TD, Greenspan JS, Blackman MA, Talal N. Natural killer cells, bone, and the bone marrow: studies in estrogen-treated mice and in congenitally osteopetrotic (mi/mi) mice. J Immunol 1979; 122: 2541-2547.
5. Beck RC, Padival M, Yeh D, Ralston J, Cooke KR, Lowe JB. The notch ligands Jagged2, Delta1, and Delta4 induce differentiation and expansion of functional human NK cells from CD34+ cord blood hematopoietic progenitor cells. Biol Blood Marrow Transplant 2009; 15: 1026-1037.
6. Lanier LL, Le AM, Civin CI, Loken MR, Phillips JH. The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J Immunol 1986; 136: 4480-4486.
7. Jacobs R, Hintzen G, Kemper A, Beul K, Kempf S, Behrens G et al. CD56bright cells differ in their KIR repertoire and cytotoxic features from CD56dim NK cells. Eur J Immunol 2001; 31: 3121-3126.
8. Cooper MA, Fehniger TA, Turner SC, Chen KS, Ghaheri BA, Ghayur T et al. Human natural killer cells: a unique innate immunoregulatory role for the CD56bright subset. Blood 2001; 97: 3146-3151.
9. Lanier LL. Up on the tightrope: natural killer cell activation and inhibition. Nat Immunol 2008; 9: 495-502.
10. Stetson DB, Mohrs M, Reinhardt RL, Baron JL, Wang ZE, Gapin L et al. Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J Exp Med 2003; 198: 1069.
11. Brown MG, Dokun AO, Heusel JW, Smith HRC, Beckman DL, Blattenberger EA et al. Vital involvement of a natural killer cell activation receptor in resistance to viral infection. Science 2001; 292: 934-937.
12. Kim S, Iizuka K, Aguila HL, Weissman IL, Yokoyama WM. In vivo natural killer cell activities revealed by natural killer cell-deficient mice. Proc Natl Acad Sci USA 2000; 97: 2731-2736.
13. Le-Barillec K, Magalhaes JG, Corcuff E, Thuizat A, Sansonetti PJ, Phalipon A et al. Roles for T and NK cells in the innate immune response to Shigella flexneri. J Immunol 2005; 175: 1735-1740.
14. Baratin M, Roetynck S, Lépolard C, Falk C, Sawadogo S, Uematsu S et al. Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum. Proc Natl Acad Sci 2005; 102: 14747-14752.
15. Dalbeth N, Gundle R, Davies R, Lee YC, McMichael AJ, Callan MF et al. CD56bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation. J Immunol 2004; 173: 6418-6426.
16. Gerosa F, Baldani-Guerra B, Nisii C, Marchesini V, Carra G, Trinchieri G. Reciprocal activating interaction between natural killer cells and dendritic cells. J Exp Med 2002; 195: 327-333.
17. Lapaque N, Walzer T, Meresse S, Vivier E, Trowsdale J. Interactions between human NK cells and macrophages in response to Salmonella infection. J Immunol 2009; 182: 4339.
18. Morandi B, Bougras G, Muller WA, Ferlazzo G, Munz C. NK cells of human secondary lymphoid tissues enhance T cell polarization via IFN- secretion. Eur J Immunol 2006; 36.
19. Piccioli D, Sbrana S, Melandri E, Valiante NM. Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells. J Exp Med 2002; 195: 335.
20. Nedvetzki S, Sowinski S, Eagle RA, Harris J, Vely F, Pende D et al. Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses. Blood 2007; 109: 3776.
21. Kloss M, Decker P, Baltz KM, Baessler T, Jung G, Rammensee HG et al. Interaction of monocytes with NK cells upon toll-like receptor-induced expression of the NKG2D ligand MICA. J Immunol 2008; 181: 6711.
22. Martinon F. Detection of immune danger signals by NALP3. J Leukoc Biol 2008; 83: 507.
23. Chen C-J, Shi Y, Hearn A, Fitzgerald K, Golenbock D, Reed G et al. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J Clin Invest 2006; 116: 2262-2271.
24. Getting SJ, Flower RJ, Parente L, Medicis RD, Lussier A, Woliztky BA et al. Molecular determinants of monosodium urate crystal-induced murine peritonitis: a role for endogenous mast cells and a distinct requirement for endothelial-derived selectins. J Pharmacol Exp Ther 1997; 283: 123-130.
25. Tramontini N, Huber C, Liu-Bryan R, Terkeltaub R, Kilgore K. Central role of complement membrane attack complex in monosodium urate crystal-induced neutrophilic rabbit knee synovitis. Arthritis Rheum 2004; 50: 2633-2639.
26. Simchowitz L, Atkinson JP, Spilberg I. Stimulation of the respiratory burst in human neutrophils by crystal phagocytosis. Arthritis Rheum 1982; 25: 181-188.
27. Gilbert C, Poubelle PE, Borgeat P, Pouliot M, Naccache PH. Crystal-induced neutrophil activation: VIII. Immediate production of prostaglandin E2 mediated by constitutive cyclooxygenase 2 in human neutrophils stimulated by urate crystals. Arthritis Rheum 2003; 48: 1137-1148.
28. Ryckman C, Gilbert C, de Medicis R, Lussier A, Vandal K, Tessier PA. Monosodium urate monohydrate crystals induce the release of the proinflammatory protein S100A8/A9 from neutrophils. J Leukoc Biol 2004; 76: 433-440.
29. Hayakawa Y, Huntington ND, Nutt SL, Smyth MJ. Functional subsets of mouse natural killer cells. Immunol Rev 2006; 214: 47.
30. Schlossman SF, Boumsell L, Gilks W, Harlan JM, Kishimoto T, Morimoto C et al. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press: Oxford, 1995.
31. Hayakawa Y, Smyth MJ. CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity 1. J Immunol 2006; 176: 1517-1524.
32. Bryceson YT, March ME, Ljunggren HG, Long EO. Activation, coactivation, and costimulation of resting human natural killer cells. Immunol Rev 2006; 214: 73.
33. Cheent K, Khakoo SI. Natural killer cells: integrating diversity with function. Immunology 2009; 126: 449-457.
34. Braud VM, Allan DSJ, O'Callaghan CA, Söderström K, D'Andrea A, Ogg GS et al. HLAE binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 1998; 391: 795-799.
35. Bakker ABH, Phillips JH, Figdor CG, Lanier LL. Killer cell inhibitory receptors for MHC class I molecules regulate lysis of melanoma cells mediated by NK cells, gammadelta- T cells, and antigen-specific CTL. J Immunol 1998; 160: 5239-5245.
36. Bauer S, Groh V, Wu J, Steinle A, Phillips JH, Lanier LL et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 1999; 285: 727.
37. Smith HRC, Heusel JW, Mehta IK, Kim S, Dorner BG, Naidenko OV et al. Recognition of a virus-encoded ligand by a natural killer cell activation receptor. Proc Natl Acad Sci 2002; 99: 8826.
38. Mandelboim O, Lieberman N, Lev M, Paul L, Arnon TI, Bushkin Y et al. Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells. Nature 2001; 409: 1055-1060.
39. Bryceson YT, March ME, Ljunggren HG, Long EO. Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood 2006; 107: 159-166.
40. Brumbaugh KM, Binstadt BA, Billadeau DD, Schoon RA, Dick CJ, Ten RM et al. Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity. J Exp Med 1997; 186: 1965-1974.
41. Gilfillan S, Ho EL, Cella M, Yokoyama WM, Colonna M. NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation. Nat Immunol 2002; 3: 1150-1155.
42. Billadeau DD, Upshaw JL, Schoon RA, Dick CJ, Leibson PJ. NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway. Nat Immunol 2003; 4: 557-564.
43. Nakajima H, Colonna M. 2B4: an NK cell activating receptor with unique specificity and signal transduction mechanism. Hum Immunol 2000; 61: 39-43.
44. Binstadt BA, Brumbaugh KM, Dick CJ, Scharenberg AM, Williams BL, Colonna M et al. Sequential involvement of Lck and SHP-1 with MHC-recognizing receptors on NK cells inhibits FcR-initiated tyrosine kinase activation. Immunity 1996; 5: 629.
45. Burshtyn DN, Scharenberg AM, Wagtmann N, Rajagopalan S, Berrada K, Yi T et al. Recruitment of tyrosine phosphatase HCP (SHP-1) by the killer cell inhibitory receptor. Immunity 1996; 4: 77.
46. Meyaard L, Adema GJ, Chang C, Woollatt E, Sutherland GR, Lanier LL et al. LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes. Immunity 1997; 7: 283-290.
47. Yusa S, Catina TL, Campbell KS. SHP-1- and phosphotyrosine-independent inhibitory signaling by a killer cell Ig-like receptor cytoplasmic domain in human NK cells. J Immunol 2002; 168: 5047-5057.
48. Gross O, Grupp C, Steinberg C, Zimmermann S, Strasser D, Hannesschlager N et al. Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF-kappa B and MAPK activation to selectively control cytokine production. Blood 2008; 112: 2421.
49. Strengell M, Matikainen S, Siren J, Lehtonen A, Foster D, Julkunen I et al. IL-21 in synergy with IL-15 or IL-18 enhances IFN- production in human NK and T cells. J Immunol 2003; 170: 5464-5469.
50. Lauzon NM, Mian F, MacKenzie R, Ashkar AA. The direct effects of toll-like receptor ligands on human NK cell cytokine production and cytotoxicity. Cell Immunol 2006; 241: 102-112.
51. Wendt K, Wilk E, Buyny S, Buer J, Schmidt RE, Jacobs R. Gene and protein characteristics reflect functional diversity of CD56dim and CD56bright NK cells. J Leukoc Biol 2006; 80: 1529.
52. Fehniger TA, Cooper MA, Nuovo GJ, Cella M, Facchetti F, Colonna M et al. CD56bright natural killer cells are present in human lymph nodes and are activated by T cellderived IL-2: a potential new link between adaptive and innate immunity. Blood 2003; 101: 3052-3057.
53. Ferlazzo G, Thomas D, Lin SL, Goodman K, Morandi B, Muller WA et al. The abundant NK cells in human secondary lymphoid tissues require activation to express killer cell Ig-like receptors and become cytolytic. J Immunol 2004; 172: 1455-1462.
54. Poli A, Michel T, Theresine M, Andres E, Hentges F, Zimmer J. CD56bright natural killer (NK) cells: an important NK cell subset. Immunology 2009; 126: 458-465.
55. Caligiuri MA, Zmuidzinas A, Manley TJ, Levine H, Smith KA, Ritz J. Functional consequences of interleukin 2 receptor expression on resting human lymphocytes. Identification of a novel natural killer cell subset with high affinity receptors. J Exp Med 1990; 171: 1509-1526.
56. Matos ME, Schnier GS, Beecher MS, Ashman LK, William DE, Caligiuri MA. Expression of a functional c-kit receptor on a subset of natural killer cells. J Exp Med 1993; 178: 1079-1084.
57. Berahovich RD, Lai NL, Wei Z, Lanier LL, Schall TJ. Evidence for NK cell subsets based on chemokine receptor expression. J Immunol 2006; 177: 7833-7840.
58. Vitale M, Chiesa M, Carlomagno S, Romagnani C, Thiel A, Moretta L et al. The small subset of CD56brightCD16- natural killer cells is selectively responsible for both cell proliferation and interferon gamma production upon interaction with dendritic cells. Eur J Immunol 2004; 34: 1715-1722.
59. Campbell JJ, Qin S, Unutmaz D, Soler D, Murphy KE, Hodge MR et al. Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire. J Immunol 2001; 166: 6477-6482.
60. Romagnani C, Juelke K, Falco M, Morandi B, D'Agostino A, Costa R et al. CD56brightCD16-killer Ig-like receptor-NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation. J Immunol 2007; 178: 4947.
61. Chan A, Hong DL, Atzberger A, Kollnberger S, Filer AD, Buckley CD et al. CD56bright human NK cells differentiate into CD56dim cells: role of contact with peripheral fibroblasts. J Immunol 2007; 179: 89.
62. Robertson MJ, Ritz J. Biology and clinical relevance of human natural killer cells. Blood 1990; 76: 2421-2438.
63. Manaster I, Mandelboim O. The unique properties of human NK cells in the uterine mucosa. Placenta 2008; 29: 60-66.
64. Strowig T, Brilot F, Munz C. Noncytotoxic functions of NK cells: direct pathogen restriction and assistance to adaptive immunity. J Immunol 2008; 180: 7785-7791.
65. Walzer T, Chiossone L, Chaix J, Calver A, Carozzo C, Garrigue-Antar L et al. Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor. Nat Immunol 2007; 8: 1337-1344.
66. Dalbeth N, Callan M. A subset of natural killer cells is greatly expanded within inflamed joints. Arthritis Rheum 2002; 46: 1763-1772.
67. Katchar K, Soderstrom K, Wahlstrom J, Eklund A, Grunewald J. Characterisation of natural killer cells and CD56+ T-cells in sarcoidosis patients. Eur Respir J 2005; 26: 77-85.
68. Ottaviani C, Nasorri F, Bedini C, de Pita O et al. CD56brightCD16-NK cells accumulate in psoriatic skin in response to CXCL10 and CCL5 and exacerbate skin inflammation. Eur J Immunol 2006; 36: 118-128.
69. Khan IA, Thomas SY, Moretto MM, Lee FS, Islam SA, Combe C et al. CCR5 is essential for NK cell trafficking and host survival following Toxoplasma gondii infection. PLoS Pathog 2006; 2: e49.
70. Harlin H, Hanson M, Johansson CC, Sakurai D, Poschke I, Norell H et al. The CD16 CD56bright NK cell subset is resistant to reactive oxygen species produced by activated granulocytes and has higher antioxidative capacity than the CD16+CD56dim subset. J Immunol 2007; 179: 4513-4519.
71. Thoren FB, Romero AI, Hermodsson S, Hellstrand K. The CD16-/CD56bright subset of NK cells is resistant to oxidant-induced cell death. J Immunol 2007; 179: 781.
72. Schierloh P, Yokobori N, Aleman M, Musella RM, Beigier-Bompadre M, Saab MA et al. Increased susceptibility to apoptosis of CD56dimCD16+ NK cells induces the enrichment of IFN- -producing CD56bright cells in tuberculous pleurisy. J Immunol 2005; 175: 6852-6860.
73. Fehniger TA, Suzuki K, Ponnappan A, VanDeusen JB, Cooper MA, Florea SM et al. Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells. J Exp Med 2001; 193: 219-232.
74. Parrish-Novak J, Dillon SR, Nelson A, Hammond A, Sprecher C, Gross JA et al. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 2000; 408: 57-63.
75. Wendt K, Wilk E, Buyny S, Schmidt RE, Jacobs R. Interleukin-21 differentially affects human natural killer cell subsets. Immunology 2007; 122: 486.
76. Eidenschenk C, Dunne J, Jouanguy E, Fourlinnie C, Gineau L, Bacq D et al. A novel primary immunodeficiency with specific natural-killer cell deficiency maps to the centromeric region of chromosome 8. Am J Hum Genet 2006; 78: 721-727.
77. Etzioni A, Eidenschenk C, Katz R, Beck R, Casanova JL, Pollack S. Fatal varicella associated with selective natural killer cell deficiency. J Pediatr 2005; 146: 423-425.
78. Biron CA, Byron KS, Sullivan JL. Severe herpesvirus infections in an adolescent without natural killer cells. N Engl J Med 1989; 320: 1731-1735.
79. Zitvogel L, Tesniere A, Kroemer G. Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat Rev Immunol 2006; 6: 715-727.
80. Hayakawa Y, Screpanti V, Yagita H, Grandien A, Ljunggren HG, Smyth MJ et al. NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy. J Immunol 2004; 172: 123-129.
81. Kashii Y, Giorda R, Herberman RB, Whiteside TL, Vujanovic NL. Constitutive expression and role of the TNF family ligands in apoptotic killing of tumor cells by human NK cells. J Immunol 1999; 163: 5358-5366.
82. Arase H, Arase N, Saito T. Fas-mediated cytotoxicity by freshly isolated natural killer cells. J Exp Med 1995; 181: 1235-1238.
83. Trapani JA, Browne KA, Smyth MJ, Jans DA. Localization of granzyme B in the nucleus. J Biol Chem 1996; 271: 4127.
84. Motyka B, Korbutt G, Pinkoski MJ, Heibein JA, Caputo A, Hobman M et al. Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis. Cell 2000; 103: 491-500.
85. Cooper MA, Fehniger TA, Caligiuri MA. The biology of human natural killer-cell subsets. Trends Immunol 2001; 22: 633-640.
86. Martin-Fontecha A, Thomsen LL, Brett S, Gerard C, Lipp M, Lanzavecchia A et al. Induced recruitment of NK cells to lymph nodes provides IFN-gamma for TH1 priming. Nat Immunol 2004; 5: 1260-1265.
87. Wallach D, Fellous M, Revel M. Preferential effect of interferon-gamma on the synthesis of HLA antigens and their mRNAs in human cells. Nature 1982; 299: 833-836.
88. Schoenborn JR, Wilson CB, Frederick WA. Regulation of interferon-gamma during innate and adaptive immune responses. Adv Immunol 2007; 96: 41-101.
89. Dunn PL, North RJ. Early gamma interferon production by natural killer cells is important in defense against murine listeriosis. Infect Immun 1991; 59: 2892-2900.
90. Orange JS, Wang B, Terhorst C, Biron CA. Requirement for natural killer cell-produced interferon gamma in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration. J ExpMed 1995; 182: 1045-1056.
91. Street SEA, Cretney E, Smyth MJ. Perforin and interferon-gamma activities independently control tumor initiation, growth, and metastasis. Blood 2001; 97: 192-197.
92. Mocikat R, Braumüller H, Gumy A, Egeter O, Ziegler H, Reusch U et al. Natural killer cells activated by MHC class Ilow targets prime dendritic cells to induce protective CD8 T cell responses. Immunity 2003; 19: 561-569.
93. Aste-Amezaga M, D'Andrea A, Kubin M, Trinchieri G. Cooperation of natural killer cell stimulatory factor/interleukin-12 with other stimuli in the induction of cytokines and cytotoxic cell-associated molecules in human T and NK cells. Cell Immunol 1994; 156: 480.
94. Peters PM, Ortaldo JR, Shalaby MR, Svedersky LP, Nedwin GE, Bringman TS et al. Natural killer-sensitive targets stimulate production of TNF-alpha but not TNF-beta (lymphotoxin) by highly purified human peripheral blood large granular lymphocytes. J Immunol 1986; 137: 2592-2598.
95. Gray JD, Hirokawa M, Horwitz DA. The role of transforming growth factor beta in the generation of suppression: an interaction between CD8+ T and NK cells. J Exp Med 1994; 180: 1937-1942.
96. Grant LR, Yao ZJ, Hedrich CM, Wang F, Moorthy A, Wilson K et al. Stat4-dependent, Tbet- independent regulation of IL-10 in NK cells. Genes Immun 2008; 9: 316-327.
97. Cuturi MC, Anegon I, Sherman F, Loudon R, Clark SC, Perussia B et al. Production of hematopoietic colony-stimulating factors by human natural killer cells. J Exp Med 1989; 169: 569-583.
98. Loza MJ, Zamai L, Azzoni L, Rosati E, Perussia B. Expression of type 1 (interferon gamma) and type 2 (interleukin-13, interleukin-5) cytokines at distinct stages of natural killer cell differentiation from progenitor cells. Blood 2002; 99: 1273-1281.
99. Bluman EM, Bartynski KJ, Avalos BR, Caligiuri MA. Human natural killer cells produce abundant macrophage inflammatory protein-1 in response to monocytederived cytokines. J Clin Invest 1996; 15: 97.
100. Dorner BG, Smith HRC, French AR, Kim S, Poursine-Laurent J, Beckman DL et al. Coordinate expression of cytokines and chemokines by NK cells during murine cytomegalovirus infection. J Immunol 2004; 172: 3119-3131.
101. Roda JM, Parihar R, Magro C, Nuovo GJ, Tridandapani S, Carson III WE. Natural killer cells produce T cell-recruiting chemokines in response to antibody-coated tumor cells. Cancer Res 2006; 66: 517-526.
102. Lucas M, Schachterle W, Oberle K, Aichele P, Diefenbach A. Dendritic cells prime natural killer cells by trans-presenting interleukin 15. Immunity 2007; 26: 503-517.
103. Chaix J, Tessmer MS, Hoebe K, Fuseri N, Ryffel B, Dalod M et al. Cutting edge: priming of NK cells by IL-18. J Immunol 2008; 181: 1627.
104. Long EO. Negative signalling by inhibitory receptors: the NK cell paradigm. Immunol Rev 2008; 224: 70.
105. Cooper MA, Elliott JM, Keyel PA, Yang L, Carrero JA, Yokoyama WM. Cytokine-induced memory-like natural killer cells. Proc Natl Acad Sci USA 2009; 106: 1915.
106. Sun JC, Lanier LL. Natural killer cells remember: an evolutionary bridge between innate and adaptive immunity? Eur J Immunol 2009; 39: 2059-2064.
107. Benson Jr DM, Yu J, Becknell B, Wei M, Freud AG, Ferketich AK et al. Stem cell factor and interleukin-2/15 combine to enhance MAPK-mediated proliferation of human natural killer cells. Blood 2009; 113: 2706.
108. Huntington ND, Puthalakath H, Gunn P, Naik E, Michalak EM, Smyth MJ et al. Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1. Nat Immunol 2007; 8: 856-863.
109. Zhang C, Zhang J, Niu J, Tian Z. Interleukin-15 improves cytotoxicity of natural killer cells via up-regulating NKG2D and cytotoxic effector molecule expression as well as STAT1 and ERK1/2 phosphorylation. Cytokine 2008; 42: 128-136.
110. Ferlazzo G, Pack M, Thomas D, Paludan C, Schmid D, Strowig T et al. Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs. Proc Natl Acad Sci USA 2004; 101: 16606-16611.
111. Granucci F, Zanoni I, Pavelka N, van Dommelen SLH, Andoniou CE, Belardelli F et al. A contribution of mouse dendritic cell-derived IL-2 for NK cell activation. J Exp Med 2004; 200: 287-295.
112. Semino C, Angelini G, Poggi A, Rubartelli A. NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1. Blood 2005; 106: 609-616.
113. Hayakawa Y, Screpanti V, Yagita H, Grandien A, Ljunggren HG, Smyth MJ et al. NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy 1. J Immunol 2004; 172: 123-129.
114. Wilson JL, Heffler LC, Charo J, Scheynius A, Bejarano MT, Ljunggren HG. Targeting of human dendritic cells by autologous NK cells. J Immunol 1999; 163: 6365-6370.
115. Ferlazzo G, Münz C. Dendritic cell interactions with NK cells from different tissues. J Clin Immunol 2009; 29: 265-273.
116. Giuliani M, Giron-Michel J, Negrini S, Vacca P, Durali D, Caignard A et al. Generation of a novel regulatory NK cell subset from peripheral blood CD34+ progenitors promoted by membrane-bound IL-15. PLoS ONE 2008; 3.
117. Ghiringhelli F, Ménard C, Terme M, Flament C, Taieb J, Chaput N et al. CD4+ CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-b- dependent manner. J Exp Med 2005; 202: 1075.
118. Smyth MJ, Teng MWL, Swann J, Kyparissoudis K, Godfrey DI, Hayakawa Y. CD4+ CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer. J Immunol 2006; 176: 1582-1587.
119. Zingoni A, Sornasse T, Cocks BG, Tanaka Y, Santoni A, Lanier LL. Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions. J Immunol 2004; 173: 3716-3724.
120. Hanna J, Gonen-Gross T, Fitchett J, Rowe T, Daniels M, Arnon TI et al. Novel APC-like properties of human NK cells directly regulate T cell activation. J Clin Invest 2004; 114: 1612-1623.
121. Yuan D, Wilder J, Dang T, Bennett M, Kumar V. Activation of B lymphocytes by NK cells. Int Immunol 1992; 4: 1373-1380.
122. Trivedi PP, Roberts PC, Wolf NA, Swanborg RH. NK cells inhibit T cell proliferation via p21-mediated cell cycle arrest. J Immunol 2005; 174: 4590-4597.
123. Lu L, Ikizawa K, Hu D, Werneck MBF, Wucherpfennig KW, Cantor H. Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway. Immunity 2007; 26: 593-604.
124. Rabinovich BA, Li J, Shannon J, Hurren R, Chalupny J, Cosman D et al. Activated, but not resting T cells can be recognized and killed by syngeneic NK cells. J Immunol 2003; 170: 3572-3576.
125. Grégoire C, Chasson L, Luci C, Tomasello E, Geissmann F, Vivier E et al. The trafficking of natural killer cells. Immunol Rev 2007; 220: 169-182.
126. Hamerman JA, Ogasawara K, Lanier LL. Cutting edge: toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor. Am Assoc Immunol 2004; 172: 2001-2005.
127. Nishibori T, Xiong H, Kawamura I, Arakawa M, Mitsuyama M. Induction of cytokine gene expression by listeriolysin O and roles of macrophages and NK cells. Infect Immun 1996; 64: 3188.
128. Haller D, Serrant P, Granato D, Schiffrin EJ, Blum S. Activation of human NK cells by staphylococci and lactobacilli requires cell contact-dependent costimulation by autologous monocytes. Clin Vaccine Immunol 2002; 9: 649-657.
129. Vankayalapati R, Garg A, Porgador A, Griffith DE, Klucar P, Safi H et al. Role of NK cell-activating receptors and their ligands in the lysis of mononuclear phagocytes infected with an intracellular bacterium. J Immunol 2005; 175: 4611-4617.
130. Newman KC, Korbel DS, Hafalla JC, Riley EM. Cross-talk with myeloid accessory cells regulates human natural killer cell interferon-gamma responses to malaria. PLoS Pathog 2006; 2: e118.
131. Gazzinelli RT, Hieny S, Wynn TA, Wolf S, Sher A. Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proc Natl Acad Sci USA 1993; 90: 6115.
132. Atochina O, Harn D. LNFPIII/LeX-stimulated macrophages activate natural killer cells via CD40-CD40 L interaction. Clin Vaccine Immunol 2005; 12: 1041-1049.
133. Welte S, Kuttruff S, Waldhauer I, Steinle A. Mutual activation of natural killer cells and monocytes mediated by NKp80-AICL interaction. Nat Immunol 2006; 7: 1334-1342.
134. DeMarco RA, Fink MP, Lotze MT. Monocytes promote natural killer cell interferon gamma production in response to the endogenous danger signal HMGB1. Mol Immunol 2005; 42: 433-444.
135. Endsley JJ, Endsley MA, Estes DM. Bovine natural killer cells acquire cytotoxic/ effector activity following activation with IL-12/15 and reduce Mycobacterium bovis BCG in infected macrophages. J Leukoc Biol 2006; 79: 71-79.
136. Schierloh P, Aleman M, Yokobori N, Alves L, Roldan N, Abbate E et al. NK cell activity in tuberculosis is associated with impaired CD11a and ICAM-1 expression: a regulatory role of monocytes in NK activation. Immunology 2005; 116: 541.
137. Poupot M, Fournie JJ, Poupot R. Trogocytosis and killing of IL-4-polarized monocytes by autologous NK cells. J Leukoc Biol 2008; 84: 1298.
138. Zhang AL, Colmenero P, Purath U, Teixeira de Matos C, Hueber W, Klareskog L et al. Natural killer cells trigger differentiation of monocytes into dendritic cells. Blood 2007; 110: 2484.
139. van Dommelen SLH, Sumaria N, Schreiber RD, Scalzo AA, Smyth MJ, Degli-Esposti MA. Perforin and granzymes have distinct roles in defensive immunity and immunopathology. Immunity 2006; 25: 835-848.
140. Roberge CJ, De Medicis R, Dayer JM, Rola-Pleszczynski M, Naccache PH, Poubelle PE. Crystal-induced neutrophil activation. V. Differential production of biologically active IL-1 and IL-1 receptor antagonist. J Immunol 1994; 152: 5485-5494.
141. Di Giovine FS, Malawista SE, Thornton E, Duff GW. Urate crystals stimulate production of tumor necrosis factor alpha from human blood monocytes and synovial cells. Cytokine mRNA and protein kinetics, and cellular distribution. J Clin Invest 1991; 87: 1375.
142. Martin WJ, Walton M, Harper J. Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal-induced murine peritoneal model of acute gout. Arthritis Rheum 2009; 60.
143. Liu R, Aupperle K, Terkeltaub R. Src family protein tyrosine kinase signaling mediates monosodium urate crystal-induced IL-8 expression by monocytic THP-1 cells. J Leukoc Biol 2001; 70: 961-968.
144. Guerne PA, Terkeltaub R, Zuraw B, Lotz M. Inflammatory microcrystals stimulate interleukin-6 production and secretion by human monocytes and synoviocytes. Arthritis Rheum 1989; 32: 1443-1452.
145. Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006; 440: 237-241.
146. Terkeltaub R, Sundy JS, Schumacher HR, Murphy F, Bookbinder S, Biedermann S et al. The IL-1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, nonrandomized, single-blind pilot study. Ann Rheum Dis 2009; 68: 1613-1617.
147. So A, De Smedt T, Revaz S, Tschopp J. A pilot study of IL-1 inhibition by anakinra in acute gout. Arthritis Res Ther 2007; 9: R28.
148. Schiltz C, Liote F, Prudhommeaux F, Meunier A, Champy R, Callebert J et al. Monosodium urate monohydrate crystal-induced inflammation in vivo: quantitative histomorphometric analysis of cellular events. Arthritis Rheum 2002; 46: 1643-1650.
149. Dallaverde E, Fan PT, Chang YH. Mechanism of action of colchicine. V. Neutrophil adherence and phagocytosis in patients with acute gout treated with colchicine. J Pharmacol Exp Ther 1982; 223: 197-202.
150. Paul HN, Marléne G, Charles JR, Caroline G, Patrice EP, André L et al. Crystal-induced neutrophil activation. I. Initiation and modulation of calcium mobilization and superoxide production by microcrystals. Arthritis Rheum 1991; 34: 333-342.
151. Barabe F, Gilbert C, Liao N, Bourgoin SG, Naccache PH. Crystal-induced neutrophil activation VI. Involvement of Fc-gamma RIIIB (CD16) and CD11b in response to inflammatory microcrystals. FASEB J 1998; 12: 209-220.
152. Kozin F, Ginsberg MH, Skosey JL. Polymorphonuclear leukocyte responses to monosodium urate crystals: modification by adsorbed serum proteins. J Rheumatol 1979; 6: 519-526.
153. Abramson S, Hoffstein ST, Weissmann G. Superoxide anion generation by human neutrophils exposed to monosodium urate. Effect of protein adsorption and complement activation. Arthritis Rheum 1982; 25: 174-180.
154. Roberge CJ, Grassi J, De Medicis R, Frobert Y, Lussier A, Naccache PH et al. Crystal-neutrophil interactions lead to interleukin-1 synthesis. Inflamm Res 1991; 34: 38-41.
155. Hachicha M, Naccache PH, McColl SR. Inflammatory microcrystals differentially regulate the secretion of macrophage inflammatory protein 1 and interleukin 8 by human neutrophils: a possible mechanism of neutrophil recruitment to sites of inflammation in synovitis. J Exp Med 1995; 182: 2019-2025.
156. Yagnik D, Evans B, Florey O, Mason J, Landis R, Haskard D. Macrophage release of transforming growth factor beta1 during resolution of monosodium urate monohydrate crystal-induced inflammation. Arthritis Rheum 2004; 50: 2273-2280.