Inhibition of prolyl hydroxylase domain-containing protein suppressed lipopolysaccharide-induced TNF-α expression

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 29, Issue 12, 2009, Pages 2132-2137

  Takeda, Kotaro ^a   Ichiki, Toshihiro ^a   Narabayashi, Eriko ^b   Inanaga, Keita ^b   Miyazaki, Ryohei ^b   Hashimoto, Toru ^b   Matsuura, Hirohide ^b   Ikeda, Jiro ^b   Miyata, Toshio ^c   Sunagawa, Kenji ^a,b  

^a Department of Advanced Therapeutics for Cardiovascular Diseases ^*  (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Hypoxia; Hypoxia inducible factor; Inflammation; Prolyl hydroxylase domain containing protein; Tumor necrosis factor alpha

Indexed keywords

DIMETHYLOXALLYL GLYCINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROLYL HYDROXYLASE DOMAIN CONTAINING PROTEIN 1; PROLYL HYDROXYLASE DOMAIN CONTAINING PROTEIN 2; PROTEIN; PROTEIN INHIBITOR; SHORT HAIRPIN RNA; TM 6008; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; INFLAMMATION; INFLAMMATORY DISEASE; MACROPHAGE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RNA INTERFERENCE; UPREGULATION;

AMINO ACIDS, DICARBOXYLIC; ANIMALS; CELL LINE; CYTOKINES; ENZYME INHIBITORS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIPOPOLYSACCHARIDES; MACROPHAGES; MACROPHAGES, PERITONEAL; MICE; NF-KAPPA B; PROCOLLAGEN-PROLINE DIOXYGENASE; RNA INTERFERENCE; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 73849101811     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.196071     Document Type: Article

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