Proteasome inhibition suppresses DNA-dependent protein kinase activation caused by camptothecin

DNA Repair

Volumn 9, Issue 1, 2010, Pages 76-82

  Sakasai, Ryo ^a   Teraoka, Hirobumi ^a   Tibbetts, Randal S ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Camptothecin; DNA damage; DNA PK; Proteasome; Topoisomerase I

Indexed keywords

ATM PROTEIN; ATR PROTEIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CAMPTOTHECIN; DNA DEPENDENT PROTEIN KINASE; DNA TOPOISOMERASE; HYDROXYUREA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE RELATED KINASE; PROTEASOME; PROTEASOME INHIBITOR; REPLICATION FACTOR A; REPLICATION FACTOR A2; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME REGULATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

CAMPTOTHECIN; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASES; DNA REPLICATION; DNA-ACTIVATED PROTEIN KINASE; ENZYME ACTIVATION; HUMANS; LEUPEPTINS; PHOSPHORYLATION; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; REPLICATION PROTEIN A;

DAMALISCUS LUNATUS;

EID: 72949105139     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2009.10.008     Document Type: Article

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