N-Myristoylation targets dihydroceramide Δ4-desaturase 1 to mitochondria: Partial involvement in the apoptotic effect of myristic acid

Biochimie

Volumn 91, Issue 11-12, 2009, Pages 1411-1419

  Beauchamp, Erwan ^a   Tekpli, Xavier ^b   Marteil, Gaëlle ^a   Lagadic Gossmann, Dominique ^b   Legrand, Philippe ^a   Rioux, Vincent ^a  

^a Agrocampus French National Institute of Health and Medical Research   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Dihydroceramide desaturase; Lipoapoptosis; Myristic acid; N Myristoylation; Rat; Sphingolipid

Indexed keywords

CASPASE; CERAMIDE; CYTOCHROME C; DIHYDROCERAMIDE DELTA 4 DESATURASE 1; MYRISTIC ACID; OXYGENASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FRACTIONATION; CELL STRAIN COS7; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; IMMUNOFLUORESCENCE MICROSCOPY; LIVER CELL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MYRISTYLATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT;

ANIMALS; APOPTOSIS; CELL FRACTIONATION; CELLS, CULTURED; CERAMIDES; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOPLASMIC RETICULUM; HEPATOCYTES; HUMANS; MYRISTIC ACID; OXIDOREDUCTASES; TRANSFECTION;

RATTUS;

EID: 72649097666     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2009.07.014     Document Type: Article

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