Induction of inducible CD4+CD25+Foxp3+ regulatory T lymphocytes by porcine reproductive and respiratory syndrome virus (PRRSV)

Veterinary Immunology and Immunopathology

Volumn 133, Issue 2-4, 2010, Pages 170-182

  Wongyanin, P ^a   Buranapraditkun, S ^a   Chokeshai usaha, K ^a   Thanawonguwech, R ^a   Suradhat, S ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

CD4+CD25+Foxp3+ lymphocytes; Pig; PRRSV; Regulatory T cell

Indexed keywords

B7 ANTIGEN; CD4 ANTIGEN; CD86 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY FOXP3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTERIVIRUS; ARTICLE; AUTOLOGOUS MIXED LYMPHOCYTE REACTION; CD4+ CD25+ T LYMPHOCYTE; CONTROLLED STUDY; DENDRITIC CELL; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE; LYMPHOCYTE COUNT; MONOCYTE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PESTIVIRUS; REGULATORY T LYMPHOCYTE; SWINE; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; DENDRITIC CELLS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE ACTIVATION; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SUS SCROFA; SWINE; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; TIME FACTORS;

CLASSICAL SWINE FEVER VIRUS; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SUIDAE; SUS;

EID: 72449205089     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetimm.2009.07.012     Document Type: Article

References (70)

1. Aluvihare V.R., and Betz A.G. The role of regulatory T cells in alloantigen tolerance. Immunol. Rev. 212 (2006) 330-343
2. Awasthi A., Carrier Y., Peron J.P., Bettelli E., Kamanaka M., Flavell R.A., Kuchroo V.K., Oukka M., and Weiner H.L. A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. Nat. Immunol. 8 (2007) 1380-1389
3. Bacchetta R., Gambineri E., and Roncarolo M.-G. Role of regulatory T cells and FOXP3 in human diseases. Curr. Rev. Allerg. Clin. Immunol. 120 (2007) 227-235
4. Baecher-Allan C., Brown J.A., Freeman G.J., and Hafler D.A. Cd4(+) cd25 (high) regulatory T cells in human peripheral blood. J. Immunol. 167 (2001) 1245-1253
5. Baecher-Allan C., and Hafler D.A. Human regulatory T cells and their role in autoimmune disease. Immunol. Rev. 212 (2006) 203-216
6. +high regulatory T cell function. J. Immunol. 169 (2002) 6210-6217
7. + regulatory T cells. Semin. Immunol. 16 (2004) 89-98
8. Basta S., Knoetig S.M., Spagnuolo-Weaver M., Allan G., and McCullough K.C. Modulation of monocytic cell activity and virus susceptibility during differentiation into macrophages. J. Immunol. 162 (1999) 3961-3969
9. Belkaid Y. Regulatory T cells and infection: a dangerous necessity. Nat. Rev. Immunol. 7 (2007) 875-888
10. Belkaid Y., Blank R.B., and Suffia I. Natural regulatory T cells and parasites: a common quest for host homeostasis. Immunol. Rev. 212 (2006) 287-300
11. Biller B.J., Elmslie R.E., Burnett R.C., Avery A.C., and Dow S.W. Use of FoxP3 expression to identify regulatory T cells in healthy dogs and dogs with cancer. Vet. Immunol. Immunopathol. 116 (2007) 69-78
12. Brusko T.M., Hulme M.A., Myhr C.B., Haller M.J., and Atkinson M.A. Assessing the in vitro suppressive capacity of regulatory T cells. Immunol. Invest. 36 (2007) 607-628
13. Carrasco C.P., Rigden R.C., Schaffner R., Gerber H., Neuhaus V., Inumaru S., Takamatsu H., Bertoni G., McCullough K.C., and Summerfield A. Porcine dendritic cells generated in vitro: morphological, phenotypic and functional properties. Immunology 104 (2001) 175-184
14. Cavanagh D. Nidovirales: a new order comprising coronaviridae and arteriviridae. Arch. Virol. 142 (1997) 629-633
15. Charerntantanakul W., Platt R., and Roth J.A. Effects of porcine reproductive and respiratory syndrome virus-infected antigen-presenting cells on T cell activation and antiviral cytokine production. Viral Immunol. 19 (2006) 646-661
16. Chung H.-K., and Chae C. Expression of interleukin-10 and interleukin-12 in piglets experimentally infected with porcine reproductive and respiratory syndrome virus (PRRSV). J. Comp. Pathol. 129 (2003) 205-212
17. Dauer M., Obermaier B., Herten J., Haerle C., Pohl K., Rothenfusser S., Schnurr M., Endres S., and Eigler A. Mature dendritic cells derived from human monocytes within 48 h: a novel strategy for dendritic cell differentiation from blood precursors. J. Immunol. 170 (2003) 4069-4076
18. Dauer M., Schad K., Herten J., Junkmann J., Bauer C., Kiefl R., Endres S., and Eigler A. FastDC derived from human monocytes within 48 h effectively prime tumor antigen-specific cytotoxic T cells. J. Immunol. Methods 302 (2005) 145-155
19. De Bruin M.G.M., Samson J.N., Voermans J.J.M., van Rooij E.M.A., De Visser Y.E., and Bianchi A.T.J. Effects of a porcine reproductive and respiratory syndrome virus infection on the development of the immune response against pseudorabies virus. Vet. Immunol. Immunopathol. 76 (2000) 125-135
20. Duan X., Nauwynck H., and Pensaert M. Effects of origin and state of differentiation and activation of monocytes/macrophages on their susceptibility to porcine reproductive and respiratory syndrome virus (PRRSV). Arch. Virol. 142 (1997) 2483-2497
21. Guan X., Peng J.R., Yuan L., Wang H., Wei Y.H., and Leng X.S. A novel, rapid strategy to form dendritomas from human dendritic cells and hepatocellular carcinoma cell line HCCLM3 cells using mature dendritic cells derived from human peripheral blood CD14+ monocytes within 48 h of in vitro culture. World J. Gastroenterol. 10 (2004) 3564-3568
22. Halbur P.G. Proceedings of the 15th International Pig Veterinary Society Congress. Birmingham, UK (1998)
23. Hartigan-O'Connor D.J., Abel K., and McCune J.M. Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression. J. Exp. Med. 204 (2007) 2679-2692
24. Hori S., Nomura T., and Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299 (2003) 1057-1061
25. Hori S., and Sakaguchi S. Foxp3: a critical regulator of the development and function of regulatory T cells. Microbes Infect. 6 (2004) 745-751
26. Humphreys I.R., de Trez C., Kinkade A., Benedict C.A., Croft M., and Ware C.F. Cytomegalovirus exploits IL-10-mediated immune regulation in the salivary glands. J. Exp. Med. 204 (2007) 1217-1225
27. Jankovic D., and Trinchieri G. IL-10 or not IL-10: that is the question. Nat. Immunol. 8 (2007) 1281-1283
28. Jiang S., Lechler R.I., He X.S., and Huang J.F. Regulatory T cells and transplantation tolerance. Hum. Immunol. 67 (2006) 765-776
29. + T-regulatory cells correlates both with surface expression of CXCR4 and activation of FIV long terminal repeat binding cellular transcriptional factors. J. Virol. 79 (2005) 4965-4976
30. Joshi A., Vahlenkamp T.W., Garg H., Tompkins W.A., and Tompkins M.B. Preferential replication of FIV in activated CD4(+)CD25(+)T cells independent of cellular proliferation. Virology 321 (2004) 307-322
31. Käser T., Gerner W., Hammer S.E., Patzl M., and Saalmuller A. Detection of Foxp3 protein expression in porcine T lymphocytes. Vet. Immunol. Immunopathol. 125 (2008) 92-101
32. Käser T., Gerner W., Hammer S.E., Patzl M., and Saalmüller A. Phenotypic and functional characterisation of porcine CD4(+)CD25(high) regulatory T cells. Vet. Immunol. Immunopathol. 122 (2008) 153-158
33. Kretschmer K., Apostolou I., Hawiger D., Khazaie K., Nussenzweig M.C., and von Boehmer H. Inducing and expanding regulatory T cell populations by foreign antigen. Nat. Immunol. 6 (2005) 1219-1227
34. Li H., and Yang H. Infection of porcine reproductive and respiratory syndrome virus suppresses the antibody response to classical swine fever virus vaccination. Vet. Microbiol. 95 (2003) 295-301
35. Lopez O.J., and Osorio F.A. Role of neutralizing antibodies in PRRSV protective immunity. Vet. Immunol. Immunopathol. 102 (2004) 155-163
36. + T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C. Blood 107 (2006) 4424-4432
37. Meier W.A., Galeota J., Osorio F.A., Husmann R.J., Schnitzlein W.M., and Zuckermann F.A. Gradual development of the interferon-gamma response of swine to porcine reproductive and respiratory syndrome virus infection or vaccination. Virology 309 (2003) 18-31
38. Moore K.W., de Waal Malefyt R., Coffman R.L., and O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19 (2001) 683-765
39. Murtaugh M.P., Xiao Z., and Zuckermann F.A. Immunological responses of swine to porcine reproductive and respiratory syndrome virus infection. Viral Immunol. 15 (2002) 533-547
40. Park J.Y., Kim H.S., and Seo S.H. Characterization of interaction between porcine reproductive and respiratory syndrome virus and porcine dendritic cells. J. Microbiol. Biotechnol. 18 (2008) 1709-1716
41. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29 (2001) e45
42. Pinyochon W., Parchariyanon S., Damrongwatanapokin S., and Tantaswasdi U. Biological characterization of swine fever virus Thai isolates. J. Thai Vet. Med. Assoc. 50 (1999) 107-117 (in Thai with English abstract)
43. Rehermann B. Chronic infections with hepatotropic viruses: mechanisms of impairment of cellular immune responses. Semin. Liver Dis. 27 (2007) 152-160
44. Rouse B.T., Sarangi P.P., and Suvas S. Regulatory T cells in virus infections. Immunol. Rev. 212 (2006) 272-286
45. Royaee A.R., Husmann R.J., Dawson H.D., Calzada-Nova G., Schnitzlein W.M., Zuckermann F.A., and Lunney J.K. Deciphering the involvement of innate immune factors in development of the host immune response to PRRSV vaccination. Vet. Immunol. Immunopathol. 102 (2004) 199-216
46. Saalmüller A., Werner T., and Fachinger V. T-helper cells from naive to committed. Vet. Immunol. Immunopathol. 87 (2002) 137-145
47. + regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22 (2004) 531-562
48. + regulatory T cells. Immunol. Rev. 212 (2006) 60-73
49. Silva-Campa E., Flores-Mendoza L., Resendiz M., Pinelli-Saavedra A., Mata-Haro V., Mwangi W., and Hernandez J. Induction of T helper 3 regulatory cells by dendritic cells infected with porcine reproductive and respiratory syndrome virus. Virology 387 (2009) 373-379
50. + natural regulatory T cells are specific for microbial antigens. J. Exp. Med. 203 (2006) 777-788
51. Summerfield A., and McCullough K.C. The porcine dendritic cell family. Dev. Comp. Immunol. 33 (2009) 299-309
52. Summerfield A., McNeilly F., Walker I., Allan G., Knoetig S.M., and McCullough K.C. Depletion of CD4(+) and CD8(high+) T-cells before the onset of viraemia during classical swine fever. Vet. Immunol. Immunopathol. 78 (2001) 3-19
53. Suradhat S., Kesdangsakonwut S., Sada W., Buranapraditkun S., Wongsawang S., and Thanawongnuwech R. Negative impact of porcine reproductive and respiratory syndrome virus infection on the efficacy of classical swine fever vaccine. Vaccine 24 (2006) 2634-2642
54. Suradhat S., and Thanawongnuwech R. Upregulation of interleukin-10 gene expression in the leukocytes of pigs infected with porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 84 (2003) 2755-2760
55. Suradhat S., Thanawongnuwech R., and Poovorawan Y. Upregulation of IL-10 gene expression in porcine peripheral blood mononuclear cells by porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 84 (2003) 453-459
56. Suvas S., and Rouse B.T. Treg control of antimicrobial T cell responses. Curr. Opin. Immunol. 18 (2006) 344-348
57. + regulatory T cell: a jack of all trades, master of regulation. Nat. Immunol. 9 (2008) 239-244
58. Thacker E.L., Thacker B.J., Young T.F., and Halbur P.G. Effect of vaccination on the potentiation of porcine reproductive and respiratory syndrome virus (PRRSV)-induced pneumonia by Mycoplasma hyopneumoniae. Vaccine 18 (2000) 1244-1252
59. Thanawongnuwech R., Amonsin A., Tasanakit A., and Damrongwatanapokin S. Genetics and geographical variation of porcine reproductive and respiratory syndrome virus (PRRSV) in Thailand. Vet. Microbiol. 101 (2004) 9-21
60. Thanawongnuwech R., Halbur P.G., Ackermann M.R., Thacker E.L., and Royer R.L. Effects of low (modified-live virus vaccine) and high (VR-2385) virulence strains of porcine reproductive and respiratory syndrome virus (PRRSV) on pulmonary clearance of copper particles in pigs. Vet. Pathol. 35 (1998) 398-406
61. + T regulatory cells. J. Immunol. 172 (2004) 4752-4761
62. + regulatory T cells in viral infections. Vet. Immunol. Immunopathol. 108 (2005) 219-225
63. Van Gucht S., Labarque G., and van Reeth K. The combination of PRRSV virus and bacterial endotoxin as a model for multifactorial respiratory disease in pigs. Vet. Immunol. Immunopathol. 102 (2004) 165-178
64. Wang H.Y., and Wang R.F. Regulatory T cells and cancer. Curr. Opin. Immunol. 19 (2007) 217-223
65. Wang X., Eaton M., Mayer M., Li H., He D., Nelson E., and Christopher-Hennings J. Porcine reproductive and respiratory syndrome virus productively infects monocyte-derived dendritic cells and compromises their antigen-presenting ability. Arch. Virol. 152 (2007) 289-303
66. Weiss L., Donkova-Petrini V., Caccavelli L., Balbo M., Carbonneil C., and Levy Y. Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients. Blood 104 (2004) 3249-3256
67. + T cells. Cell. Mol. Immunol. 3 (2006) 189-195
68. Zhou Y. Regulatory T cells and viral infections. Front. Biosci. 13 (2008) 1152-1170
69. Ziegler S.F. FOXP3: of mice and men. Annu. Rev. Immunol. 24 (2006) 209-226
70. Zuckermann F.A. Extrathymic CD4/CD8 double positive T cells. Vet. Immunol. Immunopathol. 72 (1999) 55-66