Porcine dendritic cells generated in vitro: Morphological, phenotypic and functional properties

Immunology

Volumn 104, Issue 2, 2001, Pages 175-184

  Carrasco, Carlos P ^a   Rigden, Rachael C ^a   Schaffner, Rene ^a   Gerber, Heidi ^a   Neuhaus, Viviane ^a   Inumaru, Shigeki ^b   Takamatsu, Haru ^c   Bertoni, Guiseppe ^d   McCullough, Kenneth C ^a   Summerfield, Artur ^a  

^a INSTITUTE OF VIROLOGY AND IMMUNOLOGY   (Switzerland)

^b National Institute of Animal Heath   (Japan)

^c IAH Pirbright Laboratory   (United Kingdom)

^d Institute of Veterinary Virology   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD1 ANTIGEN; CD14 ANTIGEN; CD16 ANTIGEN; CD86 ANTIGEN; FC RECEPTOR; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROCOAGULANT; STAPHYLOCOCCUS ENTEROTOXIN B; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; BONE MARROW; CELL FUNCTION; CELL MATURATION; CELL STRUCTURE; CONTROLLED STUDY; DENDRITIC CELL; DERIVATIZATION; HELPER CELL; HEMATOPOIETIC CELL; IMMUNOASSAY; LYMPHOCYTE ACTIVATION; MIXED LYMPHOCYTE REACTION; MOLECULE; MONOCYTE; NONHUMAN; PHENOTYPE; POLARIZATION; PRIORITY JOURNAL; RECEPTOR AFFINITY; REGULATORY MECHANISM; SWINE; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD14; BONE MARROW CELLS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; DENDRITIC CELLS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; MICROSCOPY, PHASE-CONTRAST; MONOCYTES; RECEPTORS, FC; RECEPTORS, IGG; SPECIES SPECIFICITY; SWINE; T-LYMPHOCYTES; TH1 CELLS; TH2 CELLS;

EID: 0034762753     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2001.01299.x     Document Type: Article

References (60)

1. Immunology of the pig
2. The pig as a potential xenograft donor
3. Xenogeneic transplantation
4. Swine as an allotransplantation model
5. The dendritic cell system and its role in immunogenicity
6. Dendritic cells and the control of immunity
7. Immunobiology of dendritic cells
8. Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion
9. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
10. Dendritic cells from mouse bone marrow: In vitro differentiation using low doses of recombinant granulocyte-macrophage colony-stimulating factor
11. High levels of an MHCII-self peptide complex on dendritic cells from the T cell areas of lymph nodes
12. An advance culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
13. Cytokine requirements for the generation of large numbers of dendritic cells from rat bone marrow cultures
14. Flt-3 ligand, in combination with bovine granulocyte-macrophage colony-stimulating factor and interleukin-4, promotes the growth of bovine bone marrow derived dendritic cells
15. GM-CSF and TNF-alpha cooperate in the generation of dendritic Langerhans cells
16. + bone marrow progenitors that are expanded by c-kit-ligand and yield pure dendritic cell colonies in the presence of granulocyte/macrophage colony stimulating factor and tumour necrosis factor alpha
17. + blood progenitors for anticancer therapy
18. + dendritic cells
19. Porcine bone marrow myeloid cells: Phenotype and adhesion molecule expression
20. Intermediate stages in monocyte-macrophage differentiation modulate phenotype and susceptibility to virus infection
21. Expression of biologically active recombinant porcine GM-CSF by baculovirus gene expression system
22. Cloning and expression in mammalian cells of porcine tumour necrosis factor alpha: Examination of biological properties
23. Nucleotide and deduced amino acid sequence of porcine interleukin 4 cDNA derived from lamina propria lymphocytes
24. Preparation and characterization of monoclonal antibodies reactive with porcine PBL
25. Characterisation of monoclonal antibodies directed against swine leukocytes
26. Characterization of a porcine CD1-specific mAb that distinguishes CD4/CD8 double-positive thymic from peripheral T lymphocytes
27. Characterization of swine leukocyte differentiation antigens
28. Report on the analyses of mAb reactive with porcine CD8 for the second international swine CD workshop
29. Summary of workshop findings for porcine myelomonocytic markers
30. The antibody MY4 recognizes CD14 on porcine monocytes and macrophages
31. Molecular cloning and identification of the porcine cytolytic trigger molecule G7 as a Fc gamma RIII alpha (CD16) homologue
32. + T cell responses costimulated by pig but not human B7
33. Differentiation between MHC-restricted and non-MHC-restricted porcine cytolytic T lymphocytes
34. A turbidimetric assay in an ELISA reader for the determination of mononuclear phagocyte procoagulant activity
35. Workshop studies on monoclonal antibodies reactive against porcine myeloid cells
36. Dendritic cells are potent antigen-presenting cells for microbial superantigens
37. Small amounts of superantigen, when presented on dendritic cells, are sufficient to initiate T cell responses
38. Control of T, cell responses to staphylococcal enterotoxins by stimulator cell MHC, class II, polymorphism
39. Monocyte tissue factor induction by lipopolysaccharide (LPS): Dependence on LPS-binding protein and CD14, and inhibition by a recombinant fragment of bactericidal/permeability-increasing protein
40. Separation of dendritic cells from highly purified human monocytes by counterflow centrifugation induces tissue factor expression
41. Identification of a novel cell type in peripheral lymphoid organs of mice. III. Functional properties in vivo
42. Identification of hematopoietic progenitors of macrophages and dendritic Langerhans cells (DL-CFU) in human bone marrow and peripheral blood
43. Developmental regulation of MHC class II transport in mouse dendritic cells
44. Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo
45. Culture and characterization of hematopoietic progenitor cells from miniature swine
46. Phenotype of porcine monocytic cells: Modulation of surface molecule expression upon monocyte differentiation into macrophages
47. Modulation of monocytic cell activity and virus susceptibility during differentiation into macrophages
48. Isolation and characterization of human peripheral blood dendritic cells
49. + hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+ TNF alpha
50. ++ cells derived in vitro from peripheral blood monocytes exhibit phenotypic and functional dendritic cell-like characteristics
51. Identification of a novel dendritic cell-like subset of CD64 (+)/CD16 (+) blood monocytes
52. Professional and non-professional antigen-presenting cells in the porcine small intestine
53. Functional and phenotypic characterization of distinct porcine dendritic cells derived from peripheral blood monocytes
54. CD14
55. Regulation of Toll-like receptors in human monocytes and dendritic cells
56. Neutrophil granulocyte-committed cells can be driven to acquire dendritic cell characteristics
57. Isolation and characterisation of pig Peyer's patch dendritic cells
58. Dendritic cells enriched from swine thymus co-express CD1, CD2 and major histocompatibility complex class II and actively stimulate alloreactive T lymphocytes
59. Morphologic and immunohistochemical features of experimentally induced allergic contact dermatitis in Göttingen minipigs