Down-regulation of the tumor suppressor gene C-terminal Src kinase: An early event during premalignant colonic epithelial hyperproliferation

FEBS Letters

Volumn 579, Issue 17, 2005, Pages 3497-3502

  Kunte, Dhananjay P ^a   Wali, Ramesh K ^a   Koetsier, Jennifer L ^a   Hart, John ^b   Kostjukova, Maria N ^c   Kilimnik, Anna Y ^c   Pyatkin, Ilia G ^c   Strelnikova, Svetlana R ^c   Roy, Hemant K ^a  

^a Evanston Northwestern Healthcare ^*  (United States)

^b UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

^c Asinex Ltd   (Russian Federation)

Author keywords

Colon cancer; Colonic hyperproliferation; Csk; Src

Indexed keywords

AZOXYMETHANE; C TERMINAL SRC KINASE; MITOGEN ACTIVATED PROTEIN KINASE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; COLON CARCINOGENESIS; COLON MUCOSA; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REPRESSION; HUMAN; HUMAN CELL; MALE; NONHUMAN; PATHOGENESIS; PRECANCER; PRIORITY JOURNAL; RAT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

ANIMALS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; COLON; COLONIC NEOPLASMS; DOWN-REGULATION; GENES, TUMOR SUPPRESSOR; HT29 CELLS; HUMANS; INTESTINAL MUCOSA; MALE; MAP KINASE KINASE 1; MAP KINASE KINASE 2; PRECANCEROUS CONDITIONS; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; RATS; RATS, INBRED F344; RNA INTERFERENCE;

EID: 21244439543     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.05.030     Document Type: Article

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