Rotenone partially reverses decreased BKCA currents in cerebral artery smooth muscle cells from streptozotocin-induced diabetic mice

Clinical and Experimental Pharmacology and Physiology

Volumn 36, Issue 10, 2009, Pages

  Dong, Ling ^a   Xie, Man Jiang ^a   Zhang, Peng ^c   Ji, Le Le ^a   Liu, Wen Chong ^a   Dong, Ming Qing ^b   Gao, Feng ^a  

^a Department of Physiology ^*  (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c Urumqi General Hospital   (China)

Author keywords

Large conductance ca2+ activated k+ channels; Reactive oxygen species; Type 1 diabetes; Vascular smooth muscle cells

Indexed keywords

HYDROGEN PEROXIDE; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; PLACEBO; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; BLOOD VESSEL TONE; BRAIN ARTERY; CALCIUM CURRENT; CONTROLLED STUDY; DRUG MECHANISM; MALE; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; SMOOTH MUSCLE FIBER; STREPTOZOCIN DIABETES; VASCULAR DISEASE; VASODILATATION;

ANIMALS; CALCIUM SIGNALING; CEREBRAL ARTERIES; DIABETES MELLITUS, EXPERIMENTAL; DRUG EVALUATION, PRECLINICAL; HYDROGEN PEROXIDE; INSECTICIDES; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MALE; MEMBRANE POTENTIALS; MICE; MICE, INBRED BALB C; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PATCH-CLAMP TECHNIQUES; ROTENONE; STREPTOZOCIN; VASOCONSTRICTION;

EID: 72449151770     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2009.05222.x     Document Type: Article

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