Neurodegeneration produced by rotenone in the mouse retina: A potential model to investigate environmental pesticide contributions to neurodegenerative diseases

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 69, Issue 18, 2006, Pages 1681-1697

  Zhang, Xian ^a   Jones, Dirk ^a   Gonzalez Lima, F ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYL SULFOXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL LOSS; CELL SIZE; CELL STRUCTURE; CONTROLLED STUDY; DEGENERATIVE DISEASE; HISTOCHEMISTRY; HISTOPATHOLOGY; MALE; MOUSE; NERVE DEGENERATION; NISSL STAINING; NONHUMAN; PRIORITY JOURNAL; RETINA GANGLION CELL; RETINA NERVE CELL;

ANIMALS; ENVIRONMENTAL POLLUTANTS; INSECTICIDES; MALE; MICE; MICE, INBRED CBA; RETINAL DEGENERATION; RETINAL GANGLION CELLS; ROTENONE; TIME FACTORS;

EID: 33746784716     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390600630203     Document Type: Article

References (45)

1. Andrews, R. M., Griffiths, P. G., Johnson, M. A., and Turnbull, D. M. 1999. Histochemical localisation of mitochondrial enzyme activity in human optic nerve and retina. Br. J. Ophthalmol. 83:231-235.
2. Barrientos, A., and Moraes, C. T. 1999. Titrating the effects of mitochondrial complex I impairment in the cell physiology. J. Biol. Chem. 274:16188-16197.
3. Barry, M. A., Halsell, C. B., and Whitehead, M. C. 1993. Organization of the nucleus of the solitary tract in the hamster: acetylcholinesterase, NADH dehydrogenase, and cytochrome oxidase histochemistry. Microsc. Res. Tech. 26:231-244.
4. Beal, M. F. 1998. Mitochondrial dysfunction in neurodegenerative diseases. Biochim. Biophys. Acta Bioenergetics 1366:211-223.
5. Berndt, J. D., Callaway, N. L., and Gonzalez-Lima, F. 2001. Effects of chronic sodium azide on brain and muscle cytochrome oxidase activity: A potential model to investigate environmental contributions to neurodegenerative diseases. J. Toxicol. Environ. Health A 63:67-77.
6. Besch, D., Leo-Kottler, B., Zrenner, E., and Wissinger, B. 1999. Leber's hereditary optic neuropathy: Clinical and molecular genetic findings in a patient with a new mutation in the ND6 gene. Graefes. Arch. Clin. Exp. Ophthalmol. 237:745-752.
7. Betarbet, R., Sherer, T. B., MacKenzie, G., Garcia-Osuna, M., Panov, A. V., and Greenamyre, J. T. 2000. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. 3:1301-1306.
8. Brown, M. D., Voljavec, A. S., Lott, M. T., MacDonald, I., and Wallace, D. C. 1992. Leber's hereditary optic neuropathy: A model for mitochondrial neurodegenerative diseases. FASEB J. 6:2791-2799.
9. Carelli, V., Ross-Cisneros, F. N., and Sadun, A. A. 2002. Optic nerve degeneration and mitochondrial dysfunction: Genetic and acquired optic neuropathies. Neurochem. Int. 40:573-584.
10. Checkoway, H., and Nelson, L. M. 1999. Epidemiologic approaches to the study of Parkinson's disease etiology. Epidemiology 10:327-336.
11. Degli Esposti, M. 1998. Inhibitors of NADH-ubiquinone reductase: An overview. Biochim. Biophys. Acta Bioenergetics 1364:222-235.
12. Drager, U. C., and Olsen, J. F. 1981. Ganglion cell distribution in the retina of the mouse. Invest. Ophthalmol. Vis. Sci. 20:285-293.
13. Dreyer, E. B., Pan, Z. H., Storm, S., and Lipton, S. A. 1994. Greater sensitivity of larger retinal ganglion cells to NMDA-mediated cell death. NeuroReport 5:629-631.
14. Ernster, L., Dallner, G., and Azzone, G. G. 1963. Differential effects of rotenone and amytal on mitochondrial electron and energy transfer. J. Biol. Chem. 238:1124-1131.
15. Ferrante, R. J., Schulz, J. B., Kowall, N. W., and Beal, M. F. 1997. Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra. Brain Res. 753:157-162.
16. Gonzalez-Lima, F., and Cada, A. 1998. Quantitative histochemistry of cytochrome oxidase activity. In Cytochrome oxidase in neuronal metabolism and Alzheimer's disease, ed. F. Gonzalez-Lima, pp. 55-90. New York: Plenum Press.
17. Gorell, J. M., Johnson, C. C., Rybicki, B. A., Peterson, E. L., and Richardson, R. J. 1998. The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living. Neurology 50:1346-1350.
18. Gosalvez, M., and Diaz-Gil, J. 1978. Rotenone: A possible environmental carcinogen? Eur. J. Cancer 14:1403-1404.
19. Hatefi, Y. 1985. The mitochondrial electron transport and oxidative phosphorylation system. Annu. Rev. Biochem. 54:1015-1069.
20. Hertzman, C., Wiens, M., Snow, B., Kelly, S., and Calne, D. 1994. A case-control study of Parkinson's disease in a horticultural region of British Columbia. Mov. Disord. 9:69-75.
21. Howell, N. 1998. Leber hereditary optic neuropathy: Respiratory chain dysfunction and degeneration of the optic nerve. Vision Res. 38:1495-1504.
22. Isenberg, J. S., and Klaunig, J. E. 2000. Role of the mitochondrial membrane permeability transition (MPT) in rotenone-induced apoptosis in liver cells. Toxicol. Sci. 53:340-351.
23. Jenner, P. 2001. Parkinson's disease, pesticides and mitochondrial dysfunction. Trends Neurosci. 24:245-246.
24. Jung, C., Higgins, C. M. J., and Xu, Z. 2002. A quantitative histochemical assay for activities of mitochondrial electron transport chain complexes in mouse spinal cord sections. J. Neurosci. Methods. 114:165-172.
25. Kageyama, G. H., and Wong-Riley, M. T. T. 1984. The histochemical localization of cytochrome oxidase in the retina and lateral geniculate nucleus of the ferret, cat, and monkey, with particular reference to retinal mosaics and on/off-center visual channels. J. Neurosci. 4:2445-2459.
26. Lindahl, P. E., and Oberg, K. E. 1961. The effect of rotenone on respiration and its point of attack. Exp. Cell Res. 23:228.
27. Manfredi, G., and Beal, M. F. 2005. Poison and antidote: A novel model to study pathogenesis and therapy of LHON. Ann. Neurol. 56:171-172.
28. Osborne, N. N., Ugarte, M., Chao, M., Chidlow, G., Bae, J. H., Wood, J. P. M., and Nash, M. S. 1999. Neuroprotection in relation to retinal ischemia and relevance to glaucoma. Surv. Ophthalmol. 43:S102-S128.
29. Owens, K. 2003. Controlling pests without harmful pesticides. http://www.noharm.org/details.cfm?ID=864&type=document. Accessed 28 June 2006.
30. Quigley, H. A., Dunkelberger, G. R., and Green, W. R. 1988. Chronic human glaucoma causing selectively greater loss of large optic nerve fibers. Ophthalmology 95:357-363.
31. Ritz, B., and Yu, F. 2000. Parkinson's disease mortality and pesticide exposure in California 1984-1994. Int. J. Epidemiol. 29:323-329.
32. Rizzo, J. F. 3rd. 1995. Adenosine triphosphate deficiency: A genre of optic neuropathy. Neurology 45:11-16.
33. Sadun, A. A., and Bassi, C. J. 1990. Optic nerve damage in Alzheimer's disease. Ophthalmology 97:9-17.
34. Sadun, A. A., Win, P. H., Ross-Cisneros, F. N., Walker, S. O., and Carelli, V. 2000. Leber's hereditary optic neuropahty differentially affects smaller axons in the optic nerve. Trans. Am. Ophthalmol. Soc. 98:223-235.
35. Salinas, J. A., Introini-Collison, I. B., Dalmaz, C., and McGaugh, J. L. 1997. Posttraining intraamygdala infusions of oxotremorine and propranolol modulate storage of memory for reductions in reward magnitude. Neurobiol. Learn. Mem. 68:51-59.
36. Schapira, A. H. V. 1998. Human complex I defects in neurodegenerative diseases. Biochim. Biophys. Acta Bioenergetics 1364:261-270.
37. Semchuk, K. M., Love, E. J., and Lee, R. G. 1992. Parkinson's disease and exposure to agricultural work and pesticide chemicals. Neurology 42:1328-1335.
38. Sherer, T. B., Kim, J. H., Betarbet, R., and Greenamyre, J. T. 2003. Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and [alpha]-synuclein aggregation. Exp. Neurol. 179:9-16.
39. Sims, K. L., Kauffman, F. C., Johnson, E. C., and Pickel, V. M. 1974. Cytochemical localization of brain nicotinamide adenine dinucleotide phosphate (oxidized)-dependent dehydrogenases qualitative and quantitative distributions. J. Histochem. Cytochem. 22:7-19.
40. Singer, T. P., and Ramsay, R. R. 1990. Mechanism of the neurotoxicity of MPTP. An update. FEBS Lett. 274:1-8.
41. Valla, J., Berndt, J. D., and Gonzalez-Lima, F. 2001. Energy hypometabolism in posterior cingulate cortex of Alzheimer's patients: Superficial laminar cytochrome oxidase associated with disease duration. J. Neurosci. 21:4923-4930.
42. Walker, J. E., Arizmendi, J. M., Dupuis, A., Fearnley, I. M., Finel, M., Medd, S. M., Pilkington, S. J., Runswick, M. J., and Skehel, J. M. 1992. Sequences of 20 subunits of NADH:ubiquinone oxidoreductase from bovine heart mitochondria. Application of a novel strategy for sequencing proteins using the polymerase chain reaction. J. Mol. Biol. 226:1051-1072.
43. Waxman, S. G., and Ritchie, J. M. 1993. Molecular dissection of the myelinated axon. Ann. Neurol. 33:121-136.
44. Wolvetang, E. J., Johnson, K. L., Krauer, K., Ralph, S. J., and Linnane, A. W. 1994. Mitochondrial respiratory chain inhibitors induce apoptosis. FEBS Lett. 339:40-44.
45. Zhang, X., Jones, D., and Gonzalez-Lima, F. 2002. Mouse model of optic neuropathy caused by mitochondrial complex I dysfunction. Neurosci. Lett. 326:97-100.