메뉴 건너뛰기




Volumn 6, Issue , 2008, Pages

Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells

Author keywords

[No Author keywords available]

Indexed keywords


EID: 72449126264     PISSN: None     EISSN: 1478811X     Source Type: Journal    
DOI: 10.1186/1478-811X-6-8     Document Type: Article
Times cited : (40)

References (47)
  • 1
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: A simple pathway becomes complex
    • DOI 10.1038/nrm2009, PII NRM2009
    • Notch signalling: a simple pathway becomes complex. SJ Bray, Nat Rev Mol Cell Biol 2006 7 9 678 689 10.1038/nrm2009 16921404 (Pubitemid 44268213)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.9 , pp. 678-689
    • Bray, S.J.1
  • 2
    • 20544447734 scopus 로고    scopus 로고
    • Notch signals control the fate of immature progenitor cells in the intestine
    • DOI 10.1038/nature03589
    • Notch signals control the fate of immature progenitor cells in the intestine. S Fre, M Huyghe, P Mourikis, S Robine, D Louvard, S Artavanis-Tsakonas, Nature 2005 435 7044 964 968 10.1038/nature03589 15959516 (Pubitemid 40896323)
    • (2005) Nature , vol.435 , Issue.7044 , pp. 964-968
    • Fre, S.1    Huyghe, M.2    Mourikis, P.3    Robine, S.4    Louvard, D.5    Artavanis-Tsakonas, S.6
  • 3
    • 33646366173 scopus 로고    scopus 로고
    • Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia
    • 10.1038/nrc1880 16612405
    • Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia. C Grabher, H von Boehmer, AT Look, Nat Rev Cancer 2006 6 5 347 359 10.1038/nrc1880 16612405
    • (2006) Nat Rev Cancer , vol.6 , Issue.5 , pp. 347-359
    • Grabher, C.1    Von Boehmer, H.2    Look, A.T.3
  • 4
    • 15544381570 scopus 로고    scopus 로고
    • Self-renewal and cancer of the gut: Two sides of a coin
    • DOI 10.1126/science.1104815
    • Self-renewal and cancer of the gut: two sides of a coin. F Radtke, H Clevers, Science 2005 307 5717 1904 1909 10.1126/science.1104815 15790842 (Pubitemid 40404692)
    • (2005) Science , vol.307 , Issue.5717 , pp. 1904-1909
    • Radtke, F.1    Clevers, H.2
  • 6
    • 28544437350 scopus 로고    scopus 로고
    • The Notch 'gospel'
    • DOI 10.1038/sj.embor.7400585, PII 7400585
    • The Notch 'gospel'. F Radtke, F Schweisguth, W Pear, EMBO Rep 2005 6 12 1120 1125 16299468 10.1038/sj.embor.7400585 (Pubitemid 41741693)
    • (2005) EMBO Reports , vol.6 , Issue.12 , pp. 1120-1125
    • Radtke, F.1    Schweisguth, F.2    Pear, W.3
  • 7
    • 34748828940 scopus 로고    scopus 로고
    • Notch signaling in gastrointestinal tract (review)
    • 17143535
    • Notch signaling in gastrointestinal tract (review). M Katoh, Int J Oncol 2007 30 1 247 251 17143535
    • (2007) Int J Oncol , vol.30 , Issue.1 , pp. 247-251
    • Katoh, M.1
  • 8
    • 1642382833 scopus 로고    scopus 로고
    • Notch signaling: Control of cell communication and cell fate
    • DOI 10.1242/dev.01074
    • Notch signaling: control of cell communication and cell fate. EC Lai, Development 2004 131 5 965 973 10.1242/dev.01074 14973298 (Pubitemid 38380451)
    • (2004) Development , vol.131 , Issue.5 , pp. 965-973
    • Lai, E.C.1
  • 9
    • 37549037911 scopus 로고    scopus 로고
    • Off the beaten pathway: The complex cross talk between Notch and NF-kappaB
    • 10.1038/labinvest.3700700 18059366
    • Off the beaten pathway: the complex cross talk between Notch and NF-kappaB. C Osipo, TE Golde, BA Osborne, LA Miele, Lab Invest 2008 88 1 11 17 10.1038/labinvest.3700700 18059366
    • (2008) Lab Invest , vol.88 , Issue.1 , pp. 11-17
    • Osipo, C.1    Golde, T.E.2    Osborne, B.A.3    Miele, L.A.4
  • 10
    • 0041355557 scopus 로고    scopus 로고
    • Notch and Presenilin: Regulated intramembrane proteolysis links development and degeneration
    • DOI 10.1146/annurev.neuro.26.041002.131334
    • Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration. D Selkoe, R Kopan, Annu Rev Neurosci 2003 26 565 597 10.1146/annurev.neuro.26.041002.131334 12730322 (Pubitemid 37064944)
    • (2003) Annual Review of Neuroscience , vol.26 , pp. 565-597
    • Selkoe, D.1    Kopan, R.2
  • 11
    • 27144512725 scopus 로고    scopus 로고
    • Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells
    • DOI 10.1038/sj.onc.1208783, PII 1208783
    • Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells. CL Curry, LL Reed, TE Golde, L Miele, BJ Nickoloff, KE Foreman, Oncogene 2005 24 42 6333 6344 15940249 (Pubitemid 41486467)
    • (2005) Oncogene , vol.24 , Issue.42 , pp. 6333-6344
    • Curry, C.L.1    Reed, L.L.2    Golde, T.E.3    Miele, L.4    Nickoloff, B.J.5    Foreman, K.E.6
  • 12
    • 0242456129 scopus 로고    scopus 로고
    • Notch signaling as a therapeutic target in cancer: A new approach to the development of cell fate modifying agents
    • Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. BJ Nickoloff, BA Osborne, L Miele, Oncogene 2003 22 42 6598 6608 10.1038/sj.onc.1206758 14528285 (Pubitemid 37372340)
    • (2003) Oncogene , vol.22 , Issue.43 , pp. 6598-6608
    • Nickoloff, B.J.1    Osborne, B.A.2    Miele, L.3
  • 13
    • 33947214529 scopus 로고    scopus 로고
    • Notch signaling, γ-secretase inhibitors, and cancer therapy
    • DOI 10.1158/0008-5472.CAN-06-3958
    • Notch signaling, gamma-secretase inhibitors, and cancer therapy. M Shih Ie, TL Wang, Cancer Res 2007 67 5 1879 1882 10.1158/0008-5472.CAN-06-3958 17332312 (Pubitemid 46424200)
    • (2007) Cancer Research , vol.67 , Issue.5 , pp. 1879-1882
    • Shih, I.-M.1    Wang, T.-L.2
  • 14
    • 27844485675 scopus 로고    scopus 로고
    • Notch and Wnt inhibitors as potential new drugs for intestinal neoplastic disease
    • DOI 10.1016/j.molmed.2005.09.008, PII S147149140500211X
    • Notch and Wnt inhibitors as potential new drugs for intestinal neoplastic disease. JH van Es, H Clevers, Trends Mol Med 2005 11 11 496 502 10.1016/j.molmed.2005.09.008 16214417 (Pubitemid 41653290)
    • (2005) Trends in Molecular Medicine , vol.11 , Issue.11 , pp. 496-502
    • Van Es, J.H.1    Clevers, H.2
  • 15
    • 8444247084 scopus 로고    scopus 로고
    • Modulation of Notch processing by γ-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation
    • DOI 10.1093/toxsci/kfh254
    • Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation. J Milano, J McKay, C Dagenais, L Foster-Brown, F Pognan, R Gadient, RT Jacobs, A Zacco, B Greenberg, PJ Ciaccio, Toxicol Sci 2004 82 1 341 358 10.1093/toxsci/kfh254 15319485 (Pubitemid 39485346)
    • (2004) Toxicological Sciences , vol.82 , Issue.1 , pp. 341-358
    • Milano, J.1    McKay, J.2    Dagenais, C.3    Foster-Brown, L.4    Pognan, F.5    Gadient, R.6    Jacobs, R.T.7    Zacco, A.8    Greenberg, B.9    Ciaccio, P.J.10
  • 18
    • 0028990125 scopus 로고
    • Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
    • 10.1016/0092-8674(95)90541-3 7774019
    • Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. M Tewari, LT Quan, K O'Rourke, S Desnoyers, Z Zeng, DR Beidler, GG Poirier, GS Salvesen, VM Dixit, Cell 1995 81 5 801 809 10.1016/0092-8674(95)90541-3 7774019
    • (1995) Cell , vol.81 , Issue.5 , pp. 801-809
    • Tewari, M.1    Quan, L.T.2    O'Rourke, K.3    Desnoyers, S.4    Zeng, Z.5    Beidler, D.R.6    Poirier, G.G.7    Salvesen, G.S.8    Dixit, V.M.9
  • 19
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
    • DOI 10.1038/sj.onc.1210422, PII 1210422
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. PJ Roberts, CJ Der, Oncogene 2007 26 22 3291 3310 10.1038/sj.onc.1210422 17496923 (Pubitemid 46763022)
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3291-3310
    • Roberts, P.J.1    Der, C.J.2
  • 20
    • 34248583886 scopus 로고    scopus 로고
    • MAP kinase signalling pathways in cancer
    • DOI 10.1038/sj.onc.1210421, PII 1210421
    • MAP kinase signalling pathways in cancer. AS Dhillon, S Hagan, O Rath, W Kolch, Oncogene 2007 26 22 3279 3290 10.1038/sj.onc.1210421 17496922 (Pubitemid 46763021)
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3279-3290
    • Dhillon, A.S.1    Hagan, S.2    Rath, O.3    Kolch, W.4
  • 21
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB Signaling: Navigating Downstream
    • DOI 10.1016/j.cell.2007.06.009, PII S0092867407007751
    • AKT/PKB signaling: navigating downstream. BD Manning, LC Cantley, Cell 2007 129 7 1261 1274 10.1016/j.cell.2007.06.009 17604717 (Pubitemid 46962095)
    • (2007) Cell , vol.129 , Issue.7 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 22
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: Opposing activities that mediate cell death
    • 10.1038/nrm2308 18097445
    • The BCL-2 protein family: opposing activities that mediate cell death. RJ Youle, A Strasser, Nat Rev Mol Cell Biol 2008 9 1 47 59 10.1038/nrm2308 18097445
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.1 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 23
    • 0030898417 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways
    • DOI 10.1016/S0955-0674(97)80061-0
    • Mitogen-activated protein kinase pathways. MJ Robinson, MH Cobb, Curr Opin Cell Biol 1997 9 2 180 186 10.1016/S0955-0674(97)80061-0 9069255 (Pubitemid 27135985)
    • (1997) Current Opinion in Cell Biology , vol.9 , Issue.2 , pp. 180-186
    • Robinson, M.J.1    Cobb, M.H.2
  • 25
    • 33846277976 scopus 로고    scopus 로고
    • P53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: A novel target of p53 in apoptosis
    • DOI 10.1016/j.febslet.2006.12.035, PII S0014579306014931
    • p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis. S Singh, AK Upadhyay, AK Ajay, MK Bhat, FEBS Lett 2007 581 2 289 295 10.1016/j.febslet.2006.12.035 17208232 (Pubitemid 46110832)
    • (2007) FEBS Letters , vol.581 , Issue.2 , pp. 289-295
    • Singh, S.1    Upadhyay, A.K.2    Ajay, A.K.3    Bhat, M.K.4
  • 26
    • 0037066686 scopus 로고    scopus 로고
    • ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53
    • DOI 10.1074/jbc.M111598200
    • ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. D Tang, D Wu, A Hirao, JM Lahti, L Liu, B Mazza, VJ Kidd, TW Mak, AJ Ingram, J Biol Chem 2002 277 15 12710 12717 10.1074/jbc.M111598200 11821415 (Pubitemid 34952631)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.15 , pp. 12710-12717
    • Tang, D.1    Wu, D.2    Hirao, A.3    Lahti, J.M.4    Liu, L.5    Mazza, B.6    Kidd, V.J.7    Mak, T.W.8    Ingram, A.J.9
  • 27
    • 0033567291 scopus 로고    scopus 로고
    • The stress-activated protein kinase pathways
    • DOI 10.1007/s000180050369
    • The stress-activated protein kinase pathways. LA Tibbles, JR Woodgett, Cell Mol Life Sci 1999 55 10 1230 1254 10.1007/s000180050369 10487205 (Pubitemid 29410745)
    • (1999) Cellular and Molecular Life Sciences , vol.55 , Issue.10 , pp. 1230-1254
    • Tibbles, L.A.1    Woodgett, J.R.2
  • 28
    • 0034671751 scopus 로고    scopus 로고
    • Requirement for ERK activation in cisplatin-induced apoptosis
    • DOI 10.1074/jbc.M004583200
    • Requirement for ERK activation in cisplatin-induced apoptosis. X Wang, JL Martindale, NJ Holbrook, J Biol Chem 2000 275 50 39435 39443 10.1074/jbc.M004583200 10993883 (Pubitemid 32058968)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.50 , pp. 39435-39443
    • Wang, X.1    Martindale, J.L.2    Holbrook, N.J.3
  • 29
    • 0033615657 scopus 로고    scopus 로고
    • Inhibition of extracellular signal-regulated protein kinase or c-Jun N- terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line
    • DOI 10.1074/jbc.274.44.31648
    • Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line. J Hayakawa, M Ohmichi, H Kurachi, H Ikegami, A Kimura, T Matsuoka, H Jikihara, D Mercola, Y Murata, J Biol Chem 1999 274 44 31648 31654 10.1074/jbc.274.44.31648 10531373 (Pubitemid 29508533)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.44 , pp. 31648-31654
    • Hayakawa, J.1    Ohmichi, M.2    Kurachi, H.3    Ikegami, H.4    Kimura, A.5    Matsuoka, T.6    Jikihara, H.7    Mercola, D.8    Murata, Y.9
  • 31
    • 0032949934 scopus 로고    scopus 로고
    • Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: Inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin
    • Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin. DL Persons, EM Yazlovitskaya, W Cui, JC Pelling, Clin Cancer Res 1999 5 5 1007 1014 10353733 (Pubitemid 29233214)
    • (1999) Clinical Cancer Research , vol.5 , Issue.5 , pp. 1007-1014
    • Persons, D.L.1    Yazlovitskaya, E.M.2    Cui, W.3    Pelling, J.C.4
  • 32
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • 10.1126/science.270.5240.1326 7481820
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Z Xia, M Dickens, J Raingeaud, RJ Davis, ME Greenberg, Science 1995 270 5240 1326 1331 10.1126/science.270.5240.1326 7481820
    • (1995) Science , vol.270 , Issue.5240 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 33
    • 13744251436 scopus 로고    scopus 로고
    • Drug therapy: Systemic therapy for colorectal cancer
    • DOI 10.1056/NEJMra040958
    • Systemic therapy for colorectal cancer. JA Meyerhardt, RJ Mayer, N Engl J Med 2005 352 5 476 487 10.1056/NEJMra040958 15689586 (Pubitemid 40175974)
    • (2005) New England Journal of Medicine , vol.352 , Issue.5 , pp. 476-487
    • Meyerhardt, J.A.1    Mayer, R.J.2
  • 35
    • 0345256652 scopus 로고    scopus 로고
    • Cisplatin: Mode of cytotoxic action and molecular basis of resistance
    • DOI 10.1038/sj.onc.1206933, Drug Resistance
    • Cisplatin: mode of cytotoxic action and molecular basis of resistance. ZH Siddik, Oncogene 2003 22 47 7265 7279 10.1038/sj.onc.1206933 14576837 (Pubitemid 37487159)
    • (2003) Oncogene , vol.22 , Issue.47 REV. ISS. 6 , pp. 7265-7279
    • Siddik, Z.H.1
  • 36
    • 34249987392 scopus 로고    scopus 로고
    • Emerging therapies for colorectal cancer
    • DOI 10.1517/13543784.16.6.867
    • Emerging therapies for colorectal cancer. AF Hezel, DP Ryan, Expert Opin Investig Drugs 2007 16 6 867 876 10.1517/13543784.16.6.867 17501698 (Pubitemid 46887127)
    • (2007) Expert Opinion on Investigational Drugs , vol.16 , Issue.6 , pp. 867-876
    • Hezel, A.F.1    Ryan, D.P.2
  • 37
    • 36949032298 scopus 로고    scopus 로고
    • Src family nonreceptor tyrosine kinases as molecular targets for cancer therapy
    • DOI 10.2174/187152007784111278
    • SRC family nonreceptor tyrosine kinases as molecular targets for cancer therapy. FM Johnson, GE Gallick, Anticancer Agents Med Chem 2007 7 6 651 659 10.2174/187152007784111278 18045060 (Pubitemid 350237770)
    • (2007) Anti-Cancer Agents in Medicinal Chemistry , vol.7 , Issue.6 , pp. 651-659
    • Johnson, F.M.1    Gallick, G.E.2
  • 38
    • 33846541373 scopus 로고    scopus 로고
    • Novel targets for anticancer treatment development in colorectal cancer
    • Novel targets for anticancer treatment development in colorectal cancer. T Macarulla, FJ Ramos, J Capdevila, C Saura, J Tabernero, Clin Colorectal Cancer 2006 6 4 265 272 10.3816/CCC.2006.n.045 17241511 (Pubitemid 46157476)
    • (2006) Clinical Colorectal Cancer , vol.6 , Issue.4 , pp. 265-272
    • Macarulla, T.1    Ramos, F.J.2    Capdevila, J.3    Saura, C.4    Tabernero, J.5
  • 39
    • 33846051923 scopus 로고    scopus 로고
    • Searching for the magic bullet: Anticancer platinum drugs which can be accumulated or activated in the tumor tissue
    • Searching for the magic bullet: anticancer platinum drugs which can be accumulated or activated in the tumor tissue. M Galanski, BK Keppler, Anticancer Agents Med Chem 2007 7 1 55 73 10.2174/187152007779314017 17266505 (Pubitemid 46062405)
    • (2007) Anti-Cancer Agents in Medicinal Chemistry , vol.7 , Issue.1 , pp. 55-73
    • Galanski, M.1    Keppler, B.K.2
  • 41
    • 34648857551 scopus 로고    scopus 로고
    • Notch emerges as new cancer drug target
    • 10.1093/jnci/djm148 17728207
    • Notch emerges as new cancer drug target. K Garber, J Natl Cancer Inst 2007 99 17 1284 1285 10.1093/jnci/djm148 17728207
    • (2007) J Natl Cancer Inst , vol.99 , Issue.17 , pp. 1284-1285
    • Garber, K.1
  • 43
    • 0034738965 scopus 로고    scopus 로고
    • Ras pathway signals are required for notch-mediated oncogenesis
    • 10.1038/sj.onc.1203766 10980592
    • Ras pathway signals are required for notch-mediated oncogenesis. K Fitzgerald, A Harrington, P Leder, Oncogene 2000 19 37 4191 4198 10.1038/sj.onc.1203766 10980592
    • (2000) Oncogene , vol.19 , Issue.37 , pp. 4191-4198
    • Fitzgerald, K.1    Harrington, A.2    Leder, P.3
  • 45
    • 33749072019 scopus 로고    scopus 로고
    • Nuclear Signaling by Receptor Tyrosine Kinases: The First Robin of Spring
    • DOI 10.1016/j.cell.2006.09.013, PII S0092867406012049
    • Nuclear signaling by receptor tyrosine kinases: the first robin of spring. J Schlessinger, MA Lemmon, Cell 2006 127 1 45 48 10.1016/j.cell.2006.09. 013 17018275 (Pubitemid 44466641)
    • (2006) Cell , vol.127 , Issue.1 , pp. 45-48
    • Schlessinger, J.1    Lemmon, M.A.2
  • 46
    • 34249664257 scopus 로고    scopus 로고
    • The insulin-like growth factor 1 (IGF-1) receptor is a substrate for γ-secretase-mediated intramembrane proteolysis
    • DOI 10.1016/j.bbrc.2007.05.062, PII S0006291X07010352
    • The insulin-like growth factor 1 (IGF-1) receptor is a substrate for gamma-secretase-mediated intramembrane proteolysis. B McElroy, JC Powell, JV McCarthy, Biochem Biophys Res Commun 2007 358 4 1136 1141 10.1016/j.bbrc.2007. 05.062 17524361 (Pubitemid 46829007)
    • (2007) Biochemical and Biophysical Research Communications , vol.358 , Issue.4 , pp. 1136-1141
    • McElroy, B.1    Powell, J.C.2    McCarthy, J.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.