-
1
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
DOI 10.1038/nrm2009, PII NRM2009
-
Notch signalling: a simple pathway becomes complex. SJ Bray, Nat Rev Mol Cell Biol 2006 7 9 678 689 10.1038/nrm2009 16921404 (Pubitemid 44268213)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.9
, pp. 678-689
-
-
Bray, S.J.1
-
2
-
-
20544447734
-
Notch signals control the fate of immature progenitor cells in the intestine
-
DOI 10.1038/nature03589
-
Notch signals control the fate of immature progenitor cells in the intestine. S Fre, M Huyghe, P Mourikis, S Robine, D Louvard, S Artavanis-Tsakonas, Nature 2005 435 7044 964 968 10.1038/nature03589 15959516 (Pubitemid 40896323)
-
(2005)
Nature
, vol.435
, Issue.7044
, pp. 964-968
-
-
Fre, S.1
Huyghe, M.2
Mourikis, P.3
Robine, S.4
Louvard, D.5
Artavanis-Tsakonas, S.6
-
3
-
-
33646366173
-
Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia
-
10.1038/nrc1880 16612405
-
Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia. C Grabher, H von Boehmer, AT Look, Nat Rev Cancer 2006 6 5 347 359 10.1038/nrc1880 16612405
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.5
, pp. 347-359
-
-
Grabher, C.1
Von Boehmer, H.2
Look, A.T.3
-
4
-
-
15544381570
-
Self-renewal and cancer of the gut: Two sides of a coin
-
DOI 10.1126/science.1104815
-
Self-renewal and cancer of the gut: two sides of a coin. F Radtke, H Clevers, Science 2005 307 5717 1904 1909 10.1126/science.1104815 15790842 (Pubitemid 40404692)
-
(2005)
Science
, vol.307
, Issue.5717
, pp. 1904-1909
-
-
Radtke, F.1
Clevers, H.2
-
5
-
-
20544460148
-
Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
DOI 10.1038/nature03659
-
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. JH van Es, ME van Gijn, O Riccio, M van den Born, M Vooijs, H Begthel, M Cozijnsen, S Robine, DJ Winton, F Radtke, H Clevers, Nature 2005 435 7044 959 963 10.1038/nature03659 15959515 (Pubitemid 40896322)
-
(2005)
Nature
, vol.435
, Issue.7044
, pp. 959-963
-
-
Van Es, J.H.1
Van Gijn, M.E.2
Riccio, O.3
Van Den Born, M.4
Vooijs, M.5
Begthel, H.6
Cozijnsen, M.7
Robine, S.8
Winton, D.J.9
Radtke, F.10
Clevers, H.11
-
6
-
-
28544437350
-
The Notch 'gospel'
-
DOI 10.1038/sj.embor.7400585, PII 7400585
-
The Notch 'gospel'. F Radtke, F Schweisguth, W Pear, EMBO Rep 2005 6 12 1120 1125 16299468 10.1038/sj.embor.7400585 (Pubitemid 41741693)
-
(2005)
EMBO Reports
, vol.6
, Issue.12
, pp. 1120-1125
-
-
Radtke, F.1
Schweisguth, F.2
Pear, W.3
-
7
-
-
34748828940
-
Notch signaling in gastrointestinal tract (review)
-
17143535
-
Notch signaling in gastrointestinal tract (review). M Katoh, Int J Oncol 2007 30 1 247 251 17143535
-
(2007)
Int J Oncol
, vol.30
, Issue.1
, pp. 247-251
-
-
Katoh, M.1
-
8
-
-
1642382833
-
Notch signaling: Control of cell communication and cell fate
-
DOI 10.1242/dev.01074
-
Notch signaling: control of cell communication and cell fate. EC Lai, Development 2004 131 5 965 973 10.1242/dev.01074 14973298 (Pubitemid 38380451)
-
(2004)
Development
, vol.131
, Issue.5
, pp. 965-973
-
-
Lai, E.C.1
-
9
-
-
37549037911
-
Off the beaten pathway: The complex cross talk between Notch and NF-kappaB
-
10.1038/labinvest.3700700 18059366
-
Off the beaten pathway: the complex cross talk between Notch and NF-kappaB. C Osipo, TE Golde, BA Osborne, LA Miele, Lab Invest 2008 88 1 11 17 10.1038/labinvest.3700700 18059366
-
(2008)
Lab Invest
, vol.88
, Issue.1
, pp. 11-17
-
-
Osipo, C.1
Golde, T.E.2
Osborne, B.A.3
Miele, L.A.4
-
10
-
-
0041355557
-
Notch and Presenilin: Regulated intramembrane proteolysis links development and degeneration
-
DOI 10.1146/annurev.neuro.26.041002.131334
-
Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration. D Selkoe, R Kopan, Annu Rev Neurosci 2003 26 565 597 10.1146/annurev.neuro.26.041002.131334 12730322 (Pubitemid 37064944)
-
(2003)
Annual Review of Neuroscience
, vol.26
, pp. 565-597
-
-
Selkoe, D.1
Kopan, R.2
-
11
-
-
27144512725
-
Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells
-
DOI 10.1038/sj.onc.1208783, PII 1208783
-
Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells. CL Curry, LL Reed, TE Golde, L Miele, BJ Nickoloff, KE Foreman, Oncogene 2005 24 42 6333 6344 15940249 (Pubitemid 41486467)
-
(2005)
Oncogene
, vol.24
, Issue.42
, pp. 6333-6344
-
-
Curry, C.L.1
Reed, L.L.2
Golde, T.E.3
Miele, L.4
Nickoloff, B.J.5
Foreman, K.E.6
-
12
-
-
0242456129
-
Notch signaling as a therapeutic target in cancer: A new approach to the development of cell fate modifying agents
-
Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. BJ Nickoloff, BA Osborne, L Miele, Oncogene 2003 22 42 6598 6608 10.1038/sj.onc.1206758 14528285 (Pubitemid 37372340)
-
(2003)
Oncogene
, vol.22
, Issue.43
, pp. 6598-6608
-
-
Nickoloff, B.J.1
Osborne, B.A.2
Miele, L.3
-
13
-
-
33947214529
-
Notch signaling, γ-secretase inhibitors, and cancer therapy
-
DOI 10.1158/0008-5472.CAN-06-3958
-
Notch signaling, gamma-secretase inhibitors, and cancer therapy. M Shih Ie, TL Wang, Cancer Res 2007 67 5 1879 1882 10.1158/0008-5472.CAN-06-3958 17332312 (Pubitemid 46424200)
-
(2007)
Cancer Research
, vol.67
, Issue.5
, pp. 1879-1882
-
-
Shih, I.-M.1
Wang, T.-L.2
-
14
-
-
27844485675
-
Notch and Wnt inhibitors as potential new drugs for intestinal neoplastic disease
-
DOI 10.1016/j.molmed.2005.09.008, PII S147149140500211X
-
Notch and Wnt inhibitors as potential new drugs for intestinal neoplastic disease. JH van Es, H Clevers, Trends Mol Med 2005 11 11 496 502 10.1016/j.molmed.2005.09.008 16214417 (Pubitemid 41653290)
-
(2005)
Trends in Molecular Medicine
, vol.11
, Issue.11
, pp. 496-502
-
-
Van Es, J.H.1
Clevers, H.2
-
15
-
-
8444247084
-
Modulation of Notch processing by γ-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation
-
DOI 10.1093/toxsci/kfh254
-
Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation. J Milano, J McKay, C Dagenais, L Foster-Brown, F Pognan, R Gadient, RT Jacobs, A Zacco, B Greenberg, PJ Ciaccio, Toxicol Sci 2004 82 1 341 358 10.1093/toxsci/kfh254 15319485 (Pubitemid 39485346)
-
(2004)
Toxicological Sciences
, vol.82
, Issue.1
, pp. 341-358
-
-
Milano, J.1
McKay, J.2
Dagenais, C.3
Foster-Brown, L.4
Pognan, F.5
Gadient, R.6
Jacobs, R.T.7
Zacco, A.8
Greenberg, B.9
Ciaccio, P.J.10
-
16
-
-
40649125574
-
Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells
-
DOI 10.1073/pnas.0712176105
-
Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells. M Emaduddin, DC Bicknell, WF Bodmer, SM Feller, Proc Natl Acad Sci USA 2008 105 7 2358 2362 18258742 10.1073/pnas.0712176105 (Pubitemid 351520518)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.7
, pp. 2358-2362
-
-
Emaduddin, M.1
Bicknell, D.C.2
Bodmer, W.F.3
Feller, S.M.4
-
17
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
10.1038/376037a0 7596430
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. DW Nicholson, A Ali, NA Thornberry, JP Vaillancourt, CK Ding, M Gallant, Y Gareau, PR Griffin, M Labelle, YA Lazebnik, et al. Nature 1995 376 6535 37 43 10.1038/376037a0 7596430
-
(1995)
Nature
, vol.376
, Issue.6535
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebnik, Y.A.10
-
18
-
-
0028990125
-
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
10.1016/0092-8674(95)90541-3 7774019
-
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. M Tewari, LT Quan, K O'Rourke, S Desnoyers, Z Zeng, DR Beidler, GG Poirier, GS Salvesen, VM Dixit, Cell 1995 81 5 801 809 10.1016/0092-8674(95)90541-3 7774019
-
(1995)
Cell
, vol.81
, Issue.5
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
Desnoyers, S.4
Zeng, Z.5
Beidler, D.R.6
Poirier, G.G.7
Salvesen, G.S.8
Dixit, V.M.9
-
19
-
-
34248591612
-
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
-
DOI 10.1038/sj.onc.1210422, PII 1210422
-
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. PJ Roberts, CJ Der, Oncogene 2007 26 22 3291 3310 10.1038/sj.onc.1210422 17496923 (Pubitemid 46763022)
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3291-3310
-
-
Roberts, P.J.1
Der, C.J.2
-
20
-
-
34248583886
-
MAP kinase signalling pathways in cancer
-
DOI 10.1038/sj.onc.1210421, PII 1210421
-
MAP kinase signalling pathways in cancer. AS Dhillon, S Hagan, O Rath, W Kolch, Oncogene 2007 26 22 3279 3290 10.1038/sj.onc.1210421 17496922 (Pubitemid 46763021)
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3279-3290
-
-
Dhillon, A.S.1
Hagan, S.2
Rath, O.3
Kolch, W.4
-
21
-
-
34250788809
-
AKT/PKB Signaling: Navigating Downstream
-
DOI 10.1016/j.cell.2007.06.009, PII S0092867407007751
-
AKT/PKB signaling: navigating downstream. BD Manning, LC Cantley, Cell 2007 129 7 1261 1274 10.1016/j.cell.2007.06.009 17604717 (Pubitemid 46962095)
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
22
-
-
37549048249
-
The BCL-2 protein family: Opposing activities that mediate cell death
-
10.1038/nrm2308 18097445
-
The BCL-2 protein family: opposing activities that mediate cell death. RJ Youle, A Strasser, Nat Rev Mol Cell Biol 2008 9 1 47 59 10.1038/nrm2308 18097445
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.1
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
23
-
-
0030898417
-
Mitogen-activated protein kinase pathways
-
DOI 10.1016/S0955-0674(97)80061-0
-
Mitogen-activated protein kinase pathways. MJ Robinson, MH Cobb, Curr Opin Cell Biol 1997 9 2 180 186 10.1016/S0955-0674(97)80061-0 9069255 (Pubitemid 27135985)
-
(1997)
Current Opinion in Cell Biology
, vol.9
, Issue.2
, pp. 180-186
-
-
Robinson, M.J.1
Cobb, M.H.2
-
24
-
-
4143131243
-
Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activation
-
DOI 10.1038/sj.bjc.6601919
-
Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activation. S Schweyer, A Soruri, O Meschter, A Heintze, F Zschunke, N Miosge, P Thelen, T Schlott, HJ Radzun, A Fayyazi, Br J Cancer 2004 91 3 589 598 10.1038/sj.bjc.6601919 15266324 (Pubitemid 39093583)
-
(2004)
British Journal of Cancer
, vol.91
, Issue.3
, pp. 589-598
-
-
Schweyer, S.1
Soruri, A.2
Meschter, O.3
Heintze, A.4
Zschunke, F.5
Miosge, N.6
Thelen, P.7
Schlott, T.8
Radzun, H.J.9
Fayyazi, A.10
-
25
-
-
33846277976
-
P53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: A novel target of p53 in apoptosis
-
DOI 10.1016/j.febslet.2006.12.035, PII S0014579306014931
-
p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis. S Singh, AK Upadhyay, AK Ajay, MK Bhat, FEBS Lett 2007 581 2 289 295 10.1016/j.febslet.2006.12.035 17208232 (Pubitemid 46110832)
-
(2007)
FEBS Letters
, vol.581
, Issue.2
, pp. 289-295
-
-
Singh, S.1
Upadhyay, A.K.2
Ajay, A.K.3
Bhat, M.K.4
-
26
-
-
0037066686
-
ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53
-
DOI 10.1074/jbc.M111598200
-
ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. D Tang, D Wu, A Hirao, JM Lahti, L Liu, B Mazza, VJ Kidd, TW Mak, AJ Ingram, J Biol Chem 2002 277 15 12710 12717 10.1074/jbc.M111598200 11821415 (Pubitemid 34952631)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.15
, pp. 12710-12717
-
-
Tang, D.1
Wu, D.2
Hirao, A.3
Lahti, J.M.4
Liu, L.5
Mazza, B.6
Kidd, V.J.7
Mak, T.W.8
Ingram, A.J.9
-
27
-
-
0033567291
-
The stress-activated protein kinase pathways
-
DOI 10.1007/s000180050369
-
The stress-activated protein kinase pathways. LA Tibbles, JR Woodgett, Cell Mol Life Sci 1999 55 10 1230 1254 10.1007/s000180050369 10487205 (Pubitemid 29410745)
-
(1999)
Cellular and Molecular Life Sciences
, vol.55
, Issue.10
, pp. 1230-1254
-
-
Tibbles, L.A.1
Woodgett, J.R.2
-
28
-
-
0034671751
-
Requirement for ERK activation in cisplatin-induced apoptosis
-
DOI 10.1074/jbc.M004583200
-
Requirement for ERK activation in cisplatin-induced apoptosis. X Wang, JL Martindale, NJ Holbrook, J Biol Chem 2000 275 50 39435 39443 10.1074/jbc.M004583200 10993883 (Pubitemid 32058968)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.50
, pp. 39435-39443
-
-
Wang, X.1
Martindale, J.L.2
Holbrook, N.J.3
-
29
-
-
0033615657
-
Inhibition of extracellular signal-regulated protein kinase or c-Jun N- terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line
-
DOI 10.1074/jbc.274.44.31648
-
Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line. J Hayakawa, M Ohmichi, H Kurachi, H Ikegami, A Kimura, T Matsuoka, H Jikihara, D Mercola, Y Murata, J Biol Chem 1999 274 44 31648 31654 10.1074/jbc.274.44.31648 10531373 (Pubitemid 29508533)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.44
, pp. 31648-31654
-
-
Hayakawa, J.1
Ohmichi, M.2
Kurachi, H.3
Ikegami, H.4
Kimura, A.5
Matsuoka, T.6
Jikihara, H.7
Mercola, D.8
Murata, Y.9
-
30
-
-
0037016706
-
Activation of extracellular signal-regulated kinase by ultraviolet is mediated through Src-dependent epidermal growth factor receptor phosphorylation. Its implication in an anti-apoptotic function
-
DOI 10.1074/jbc.M107110200
-
Activation of extracellular signal-regulated kinase by ultraviolet is mediated through Src-dependent epidermal growth factor receptor phosphorylation. Its implication in an anti-apoptotic function. D Kitagawa, S Tanemura, S Ohata, N Shimizu, J Seo, G Nishitai, T Watanabe, K Nakagawa, H Kishimoto, T Wada, T Tezuka, T Yamamoto, H Nishina, T Katada, J Biol Chem 2002 277 1 366 371 10.1074/jbc.M107110200 11694531 (Pubitemid 34952067)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.1
, pp. 366-371
-
-
Kitagawa, D.1
Tanemura, S.2
Ohata, S.3
Shimizu, N.4
Seo, J.5
Nishitai, G.6
Watanabe, T.7
Nakagawa, K.8
Kishimoto, H.9
Wada, T.10
Tezuka, T.11
Yamamoto, T.12
Nishina, H.13
Katada, T.14
-
31
-
-
0032949934
-
Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: Inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin
-
Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin. DL Persons, EM Yazlovitskaya, W Cui, JC Pelling, Clin Cancer Res 1999 5 5 1007 1014 10353733 (Pubitemid 29233214)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.5
, pp. 1007-1014
-
-
Persons, D.L.1
Yazlovitskaya, E.M.2
Cui, W.3
Pelling, J.C.4
-
32
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
10.1126/science.270.5240.1326 7481820
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Z Xia, M Dickens, J Raingeaud, RJ Davis, ME Greenberg, Science 1995 270 5240 1326 1331 10.1126/science.270.5240.1326 7481820
-
(1995)
Science
, vol.270
, Issue.5240
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
33
-
-
13744251436
-
Drug therapy: Systemic therapy for colorectal cancer
-
DOI 10.1056/NEJMra040958
-
Systemic therapy for colorectal cancer. JA Meyerhardt, RJ Mayer, N Engl J Med 2005 352 5 476 487 10.1056/NEJMra040958 15689586 (Pubitemid 40175974)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.5
, pp. 476-487
-
-
Meyerhardt, J.A.1
Mayer, R.J.2
-
34
-
-
0036052558
-
Cellular and molecular pharmacology of oxaliplatin
-
12467217
-
Cellular and molecular pharmacology of oxaliplatin. E Raymond, S Faivre, S Chaney, J Woynarowski, E Cvitkovic, Mol Cancer Ther 2002 1 3 227 235 12467217
-
(2002)
Mol Cancer Ther
, vol.1
, Issue.3
, pp. 227-235
-
-
Raymond, E.1
Faivre, S.2
Chaney, S.3
Woynarowski, J.4
Cvitkovic, E.5
-
35
-
-
0345256652
-
Cisplatin: Mode of cytotoxic action and molecular basis of resistance
-
DOI 10.1038/sj.onc.1206933, Drug Resistance
-
Cisplatin: mode of cytotoxic action and molecular basis of resistance. ZH Siddik, Oncogene 2003 22 47 7265 7279 10.1038/sj.onc.1206933 14576837 (Pubitemid 37487159)
-
(2003)
Oncogene
, vol.22
, Issue.47 REV. ISS. 6
, pp. 7265-7279
-
-
Siddik, Z.H.1
-
36
-
-
34249987392
-
Emerging therapies for colorectal cancer
-
DOI 10.1517/13543784.16.6.867
-
Emerging therapies for colorectal cancer. AF Hezel, DP Ryan, Expert Opin Investig Drugs 2007 16 6 867 876 10.1517/13543784.16.6.867 17501698 (Pubitemid 46887127)
-
(2007)
Expert Opinion on Investigational Drugs
, vol.16
, Issue.6
, pp. 867-876
-
-
Hezel, A.F.1
Ryan, D.P.2
-
37
-
-
36949032298
-
Src family nonreceptor tyrosine kinases as molecular targets for cancer therapy
-
DOI 10.2174/187152007784111278
-
SRC family nonreceptor tyrosine kinases as molecular targets for cancer therapy. FM Johnson, GE Gallick, Anticancer Agents Med Chem 2007 7 6 651 659 10.2174/187152007784111278 18045060 (Pubitemid 350237770)
-
(2007)
Anti-Cancer Agents in Medicinal Chemistry
, vol.7
, Issue.6
, pp. 651-659
-
-
Johnson, F.M.1
Gallick, G.E.2
-
38
-
-
33846541373
-
Novel targets for anticancer treatment development in colorectal cancer
-
Novel targets for anticancer treatment development in colorectal cancer. T Macarulla, FJ Ramos, J Capdevila, C Saura, J Tabernero, Clin Colorectal Cancer 2006 6 4 265 272 10.3816/CCC.2006.n.045 17241511 (Pubitemid 46157476)
-
(2006)
Clinical Colorectal Cancer
, vol.6
, Issue.4
, pp. 265-272
-
-
Macarulla, T.1
Ramos, F.J.2
Capdevila, J.3
Saura, C.4
Tabernero, J.5
-
39
-
-
33846051923
-
Searching for the magic bullet: Anticancer platinum drugs which can be accumulated or activated in the tumor tissue
-
Searching for the magic bullet: anticancer platinum drugs which can be accumulated or activated in the tumor tissue. M Galanski, BK Keppler, Anticancer Agents Med Chem 2007 7 1 55 73 10.2174/187152007779314017 17266505 (Pubitemid 46062405)
-
(2007)
Anti-Cancer Agents in Medicinal Chemistry
, vol.7
, Issue.1
, pp. 55-73
-
-
Galanski, M.1
Keppler, B.K.2
-
40
-
-
37549002543
-
Isolation of rare circulating tumour cells in cancer patients by microchip technology
-
10.1038/nature06385 18097410
-
Isolation of rare circulating tumour cells in cancer patients by microchip technology. S Nagrath, LV Sequist, S Maheswaran, DW Bell, D Irimia, L Ulkus, MR Smith, EL Kwak, S Digumarthy, A Muzikansky, P Ryan, UJ Balis, RG Tompkins, DA Haber, M Toner, Nature 2007 450 7173 1235 1239 10.1038/nature06385 18097410
-
(2007)
Nature
, vol.450
, Issue.7173
, pp. 1235-1239
-
-
Nagrath, S.1
Sequist, L.V.2
Maheswaran, S.3
Bell, D.W.4
Irimia, D.5
Ulkus, L.6
Smith, M.R.7
Kwak, E.L.8
Digumarthy, S.9
Muzikansky, A.10
Ryan, P.11
Balis, U.J.12
Tompkins, R.G.13
Haber, D.A.14
Toner, M.15
-
41
-
-
34648857551
-
Notch emerges as new cancer drug target
-
10.1093/jnci/djm148 17728207
-
Notch emerges as new cancer drug target. K Garber, J Natl Cancer Inst 2007 99 17 1284 1285 10.1093/jnci/djm148 17728207
-
(2007)
J Natl Cancer Inst
, vol.99
, Issue.17
, pp. 1284-1285
-
-
Garber, K.1
-
42
-
-
0036734148
-
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells
-
DOI 10.1038/nm754
-
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. S Weijzen, P Rizzo, M Braid, R Vaishnav, SM Jonkheer, A Zlobin, BA Osborne, S Gottipati, JC Aster, WC Hahn, M Rudolf, K Siziopikou, WM Kast, L Miele, Nat Med 2002 8 9 979 986 10.1038/nm754 12185362 (Pubitemid 35033702)
-
(2002)
Nature Medicine
, vol.8
, Issue.9
, pp. 979-986
-
-
Weijzen, S.1
Rizzo, P.2
Braid, M.3
Vaishnav, R.4
Jonkheer, S.M.5
Zlobin, A.6
Osborne, B.A.7
Gottipati, S.8
Aster, J.C.9
Hahn, W.C.10
Rudolf, M.11
Siziopikou, K.12
Martin Kast, W.13
Miele, L.14
-
43
-
-
0034738965
-
Ras pathway signals are required for notch-mediated oncogenesis
-
10.1038/sj.onc.1203766 10980592
-
Ras pathway signals are required for notch-mediated oncogenesis. K Fitzgerald, A Harrington, P Leder, Oncogene 2000 19 37 4191 4198 10.1038/sj.onc.1203766 10980592
-
(2000)
Oncogene
, vol.19
, Issue.37
, pp. 4191-4198
-
-
Fitzgerald, K.1
Harrington, A.2
Leder, P.3
-
44
-
-
0035300448
-
Notch signaling induces cell cycle arrest in small cell lung cancer cells
-
Notch signaling induces cell cycle arrest in small cell lung cancer cells. V Sriuranpong, MW Borges, RK Ravi, DR Arnold, BD Nelkin, SB Baylin, DW Ball, Cancer Res 2001 61 7 3200 3205 11306509 (Pubitemid 32691976)
-
(2001)
Cancer Research
, vol.61
, Issue.7
, pp. 3200-3205
-
-
Sriuranpong, V.1
Borges, M.W.2
Ravi, R.K.3
Arnold, D.R.4
Nelkin, B.D.5
Baylin, S.B.6
Ball, D.W.7
-
45
-
-
33749072019
-
Nuclear Signaling by Receptor Tyrosine Kinases: The First Robin of Spring
-
DOI 10.1016/j.cell.2006.09.013, PII S0092867406012049
-
Nuclear signaling by receptor tyrosine kinases: the first robin of spring. J Schlessinger, MA Lemmon, Cell 2006 127 1 45 48 10.1016/j.cell.2006.09. 013 17018275 (Pubitemid 44466641)
-
(2006)
Cell
, vol.127
, Issue.1
, pp. 45-48
-
-
Schlessinger, J.1
Lemmon, M.A.2
-
46
-
-
34249664257
-
The insulin-like growth factor 1 (IGF-1) receptor is a substrate for γ-secretase-mediated intramembrane proteolysis
-
DOI 10.1016/j.bbrc.2007.05.062, PII S0006291X07010352
-
The insulin-like growth factor 1 (IGF-1) receptor is a substrate for gamma-secretase-mediated intramembrane proteolysis. B McElroy, JC Powell, JV McCarthy, Biochem Biophys Res Commun 2007 358 4 1136 1141 10.1016/j.bbrc.2007. 05.062 17524361 (Pubitemid 46829007)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.358
, Issue.4
, pp. 1136-1141
-
-
McElroy, B.1
Powell, J.C.2
McCarthy, J.V.3
-
47
-
-
21844448354
-
Spatial segregation of γ-secretase and substrates in distinct membrane domains
-
DOI 10.1074/jbc.M503570200
-
Spatial segregation of gamma-secretase and substrates in distinct membrane domains. KS Vetrivel, H Cheng, SH Kim, Y Chen, NY Barnes, AT Parent, SS Sisodia, G Thinakaran, J Biol Chem 2005 280 27 25892 25900 15886206 10.1074/jbc.M503570200 (Pubitemid 40962301)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.27
, pp. 25892-25900
-
-
Vetrivel, K.S.1
Cheng, H.2
Kim, S.-H.3
Chen, Y.4
Barnes, N.Y.5
Parent, A.T.6
Sisodia, S.S.7
Thinakaran, G.8
|