Structure and function of the intracellular region of the plexin-B1 transmembrane receptor

Journal of Biological Chemistry

Volumn 284, Issue 51, 2009, Pages 35962-35972

  Tong, Yufeng ^a   Hota, Prasanta K ^b   Penachioni, Junia Y ^c   Hamaneh, Mehdi B ^b   Kim, SoonJeung ^b   Alviani, Rebecca S ^b   Shen, Limin ^a   He, Hao ^a   Tempel, Wolfram ^a   Tamagnone, Luca ^c   Park, Hee Won ^a,b,d   Buck, Matthias ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TURIN   (Italy)

^d Structural Genomics Consortium   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; PROTEINS;

CELL-BASED ASSAYS; GTPASE-ACTIVATING PROTEIN; GTPASE-BINDING DOMAINS; INTRACELLULAR DOMAIN; MUTANT PROTEINS; STRUCTURAL BASIS; STRUCTURAL HOMOLOGY; TRANSMEMBRANE RECEPTORS;

CRYSTAL STRUCTURE;

GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MEMBRANE PROTEIN; MONOMER; MUTANT PROTEIN; RAS PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSMEMBRANE RECEPTOR PLEXIN B1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ASSAY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVATION; ENZYME BINDING; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; STRUCTURAL HOMOLOGY;

EID: 72149087958     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.056275     Document Type: Article

References (48)

1. Tamagnone, L., and Comoglio, P. M. (2000) Trends Cell Biol. 10, 377-383
2. Kruger, R. P., Aurandt, J., and Guan, K. L. (2005) Nat. Rev. Mol. Cell Biol. 6, 789-800
3. Neufeld, G., Shraga-Heled, N., Lange, T., Guttmann-Raviv, N., Herzog, Y., and Kessler, O. (2005) Front. Biosci. 10, 751-760
4. Pasterkamp, R. J., and Verhaagen, J. (2001) Brain Res. Brain Res. Rev. 35, 36-54
5. Oinuma, I., Ishikawa, Y., Katoh, H., and Negishi, M. (2004) Science 305, 862-865
6. Toyofuku, T., Yoshida, J., Sugimoto, T., Zhang, H., Kumanogoh, A., Hori, M., and Kikutani, H. (2005) Nat. Neurosci. 8, 1712-1719
7. Uesugi, K., Oinuma, I., Katoh, H., and Negishi, M. (2009) J. Biol. Chem. 284, 6743-6751
8. Oinuma, I., Katoh, H., and Negishi, M. (2004) J. Neurosci. 24, 11473-11480
9. Ohba, Y., Mochizuki, N., Yamashita, S., Chan, A. M., Schrader, J. W., Hattori, S., Nagashima, K., and Matsuda, M. (2000) J. Biol. Chem. 275, 20020-20026
10. Rohm, B., Rahim, B., Kleiber, B., Hovatta, I., and Püschel, A. W. (2000) FEBS Lett. 486, 68-72
11. Pasterkamp, R. J. (2005) Trends Cell Biol. 15, 61-64
12. Püschel, A. W. (2007) Adv. Exp. Med. Biol. 600, 12-23
13. Turner, L. J., Nicholls, S., and Hall, A. (2004) J. Biol. Chem. 279, 33199-33205
14. Vetter, I. R., and Wittinghofer, A. (2001) Science 294, 1299-1304
15. Bos, J. L., Rehmann, H., and Wittinghofer, A. (2007) Cell 129, 865-877
16. Canagarajah, B., Leskow, F. C., Ho, J. Y., Mischak, H., Saidi, L. F., Kazanietz, M. G., and Hurley, J. H. (2004) Cell 119, 407-418
17. Pena, V., Hothorn, M., Eberth, A., Kaschau, N., Parret, A., Gremer, L., Bonneau, F., Ahmadian, M. R., and Scheffzek, K. (2008) EMBO Rep. 9, 350-355
18. Drugan, J. K., Rogers-Graham, K., Gilmer, T., Campbell, S., and Clark, G. J. (2000) J. Biol. Chem. 275, 35021-35027
19. Tong, Y., Hughes, D., Placanica, L., and Buck, M. (2005) Structure 13, 7-15
20. Tong, Y., Hota, P. K., Hamaneh, M. B., and Buck, M. (2008) Structure 16, 246-258
21. Tong, Y., Chugha, P., Hota, P. K., Alviani, R. S., Li, M., Tempel, W., Shen, L., Park, H. W., and Buck, M. (2007) J. Biol. Chem. 282, 37215-37224
22. Antipenko, A., Himanen, J. P., van Leyen, K., Nardi-Dei, V., Lesniak, J., Barton, W. A., Rajashankar, K. R., Lu, M., Hoemme, C., Puschel, A. W., and Nikolov, D. B. (2003) Neuron 39, 589-598
23. Vikis, H. G., Li, W., and Guan, K. L. (2002) Genes Dev. 16, 836-845
24. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
25. Terwilliger, T. C. (2003) Methods Enzymol. 374, 22-37
26. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119
27. Vagin, A., and Teplyakov, A. (1997) J. Appl. Crystallogr. 30, 1022-1025
28. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta. Crystallogr. D Biol. Crystallogr. 53, 240-255
29. Davis, I. W., Murray, L. W., Richardson, J. S., and Richardson, D. C. (2004) Nucleic Acids Res. 32, W615-W619
30. Emsley, P., and Cowtan, K. (2004) Acta. Crystallogr. D Biol. Crystallogr. 60, 2126-2132
31. Fiser, A., and Sali, A. (2003) Methods Enzymol. 374, 461-491
32. Barberis, D., Artigiani, S., Casazza, A., Corso, S., Giordano, S., Love, C. A., Jones, E. Y., Comoglio, P. M., and Tamagnone, L. (2004) FASEB J. 18, 592-594
33. Bouguet-Bonnet, S., and Buck, M. (2008) J. Mol. Biol. 377, 1474-1487
34. Ahmadian, M. R., Kiel, C., Stege, P., and Scheffzek, K. (2003) J. Mol. Biol. 329, 699-710
35. Bernards, A., and Settleman, J. (2004) Trends Cell Biol. 14, 377-385
36. Radley, T. L., Markowska, A. I., Bettinger, B. T., Ha, J. H., and Loh, S. N. (2003) J. Mol. Biol. 332, 529-536
37. Hota, P. K., and Buck, M. (2009) Protein Sci. 18, 1060-1071
38. Vilar, M., Charalampopoulos, I., Kenchappa, R. S., Simi, A., Karaca, E., Reversi, A., Choi, S., Bothwell, M., Mingarro, I., Friedman, W. J., Schiavo, G., Bastiaens, P. I., Verveer, P. J., Carter, B. D., and Ibañez, C. F. (2009) Neuron 62, 72-83
39. Takahashi, T., and Strittmatter, S. M. (2001) Neuron 29, 429-439
40. Scheffzek, K., Ahmadian, M. R., Kabsch, W., Wiesmüller, L., Lautwein, A., Schmitz, F., and Wittinghofer, A. (1997) Science 277, 333-338
41. Scheffzek, K., Lautwein, A., Kabsch, W., Ahmadian, M. R., and Wittinghofer, A. (1996) Nature 384, 591-596
42. Mittal, R., Ahmadian, M. R., Goody, R. S., and Wittinghofer, A. (1996) Science 273, 115-117
43. Ehrhardt, A., Ehrhardt, G. R., Guo, X., and Schrader, J. W. (2002) Exp. Hematol. 30, 1089-1106
44. Venkateswarlu, K., Brandom, K. G., and Lawrence, J. L. (2004) J. Biol. Chem. 279, 6205-6208
45. Buck, M., Xu, W., and Rosen, M. K. (2004) J. Mol. Biol. 338, 271-285
46. Takagi, J., Petre, B. M., Walz, T., and Springer, T. A. (2002) Cell 110, 599-611
47. Barr, A. J., Ugochukwu, E., Lee, W. H., King, O. N., Filippakopoulos, P., Alfano, I., Savitsky, P., Burgess-Brown, N. A., Müller, S., and Knapp, S. (2009) Cell 136, 352-363
48. He, H., Taehong, Y., Terman, J. R., and Zhang, X. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 15610-15615