A two-state allosteric model for autoinhibition rationalizes WASP signal integration and targeting

Journal of Molecular Biology

Volumn 338, Issue 2, 2004, Pages 271-285

  Buck, Matthias ^a,b   Xu, Wei ^a,c   Rosen, Michael K ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c FOX CHASE CANCER CENTER   (United States)

Author keywords

Allosteric; Cytoskeleton Cdc42 GTPase; GBD, GTPase binding domain; Signal transduction; VCA, verprolin homology region, central hydrophobic and acidic C terminal region of WASP; WASP, Wiskott Aldrich syndrome protein; Wiskott Aldrich

Indexed keywords

ACTIN RELATED PROTEIN 2; ACTIN RELATED PROTEIN 3; GUANOSINE TRIPHOSPHATASE; PROTEIN CDC42; WISKOTT ALDRICH SYNDROME PROTEIN;

ALLOSTERISM; ARTICLE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PREDICTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; PROTON TRANSPORT; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; THERMODYNAMICS;

VESPIDAE;

EID: 1842505060     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.02.036     Document Type: Article

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