Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain

Journal of Biological Chemistry

Volumn 282, Issue 51, 2007, Pages 37215-37224

  Tong, Yufeng ^a,b   Chugha, Preeti ^a   Hota, Prasanta K ^a   Alviani, Rebecca S ^a   Li, Mei ^a   Tempel, Wolfram ^b   Shen, Limin ^b   Park, Hee Won ^b,c   Buck, Matthias ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; DIMERIZATION; DIMERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; X RAY CRYSTALLOGRAPHY;

BIDIRECTIONAL SIGNALING; SIGNALING MECHANISM; TRANSMEMBRANE RECEPTORS;

PROTEINS;

ACTIN; GUANOSINE TRIPHOSPHATASE; PLEXIN; PLEXIN B1; PROTEIN CDC42; PROTEIN RHOD; PROTEIN RND1; RAC PROTEIN; RAC1 PROTEIN; RHO FACTOR; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BETA CHAIN; BETA SHEET; CELL MOTION; CONFORMATIONAL TRANSITION; CYTOSKELETON; DIMERIZATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TERTIARY STRUCTURE; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 37549021146     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M703800200     Document Type: Article

References (50)

1. Negishi, M., Oinuma, I., and Katoh, H. (2005) Cell. Mol. Life Sci. 62, 1363-1371
2. Patel, B. N., and Van Vactor, D. L. (2002) Curr. Opin. Cell Biol. 14, 221-229
3. Artigiani, S., Comoglio, P. M., and Tamagnone, L. (1999) IUBMB Life 48, 477-482
4. Toyofuku, T., Zhang, H., Kumanogoh, A., Takegahara, N., Suto, F., Kamei, J., Aoki, K., Yabuki, M., Hori, M., Fujisawa, H., and Kikutani, H. (2004) Genes Dev. 18, 435-447
5. Gitler, A. D., Lu, M. M., and Epstein, J. A. (2004) Dev. Cell 7, 107-116
6. Serini, G., Valdembri, D., Zanivan, S., Morterra, G., Burkhardt, C., Caccavari, F., Zammataro, L., Primo, L., Tamagnone, L., Logan, M., Tessier-Lavigne, M., Taniguchi, M., Puschel, A. W., and Bussolino, F. (2003) Nature 424, 391-397
7. Basile, J. R., Barac, A., Zhu, T., Guan, K. L., and Gutkind, J. S. (2004) Cancer Res. 64, 5212-5224
8. Torres-Vazquez, J., Gitler, A. D., Fraser, S. D., Berk, J. D., Van, N. P., Fishman, M. C., Childs, S., Epstein, J. A., and Weinstein, B. M. (2004) Dev. Cell 7, 117-123
9. Giordano, S., Corso, S., Conrotto, P., Artigiani, S., Gilestro, G., Barberis, D., Tamagnone, L., and Comoglio, P. M. (2002) Nat. Cell Biol. 4, 720-724
10. Wong, A. W., Brickey, W. J., Taxman, D. J., van Deventer, H. W., Reed, W., Gao, J. X., Zheng, P., Liu, Y., Li, P., Blum, J. S., McKinnon, K. P., and Ting, J. P. (2003) Nat. Immunol. 4, 891-898
11. Tamagnone, L., Artigiani, S., Chen, H., He, Z., Ming, G. I., Song, H., Chedotal, A., Winberg, M. L., Goodman, C. S., Poo, M., Tessier-Lavigne, M., and Comoglio, P. M. (1999) Cell 99, 71-80
12. Vikis, H. G., Li, W., He, Z., and Guan, K. L. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 12457-12462
13. Driessens, M. H., Hu, H., Nobes, C. D., Self, A., Jordens, I., Goodman, C. S., and Hall, A. (2001) Curr. Biol. 11, 339-344
14. Hu, H., Marton, T. F., and Goodman, C. S. (2001) Neuron 32, 39-51
15. Rohm, B., Rahim, B., Kleiber, B., Hovatta, I., and Puschel, A. W. (2000) FEBS Lett. 486, 68-72
16. Nobes, C. D., and Hall, A. (1999) J. Cell Biol. 144, 1235-1244
17. Zanata, S. M., Hovatta, I., Rohm, B., and Puschel, A. W. (2002) J. Neurosci. 22, 471-477
18. Ridley, A. J. (2006) Trends Cell Biol. 16, 522-529
19. Vikis, H. G., Li, W., and Guan, K. L. (2002) Genes Dev. 16, 836-845
20. Oinuma, I., Ishikawa, Y., Katoh, H., and Negishi, M. (2004) Science 305, 862-865
21. Oinuma, I., Katoh, H., and Negishi, M. (2004) J. Neurosci. 24, 11473-11480
22. Swiercz, J. M., Kuner, R., and Offermanns, S. (2004) J. Cell Biol. 165, 869-880
23. Oinuma, I., Katoh, H., Harada, A., and Negishi, M. (2003) J. Biol. Chem. 278, 25671-25677
24. Kruger, R. P., Aurandt, J., and Guan, K. L. (2005) Nat. Rev. Mol. Cell Biol. 6, 789-800
25. Turner, L. J., Nicholls, S., and Hall, A. (2004) J. Biol. Chem. 279, 33199-33205
26. Tong, Y., and Buck, M. (2005) J. Biomol. NMR 31, 369-370
27. Bouguet-Bonnet, S., and Buck, M. (2006) J. Biomol. NMR 36, 51
28. Tong, Y. F., Hughes, D., Placanica, L., and Buck, M. (2005) Structure (Camb.) 13, 7-15
29. Wang, B. C. (1985) Methods Enzymol. 115, 90-112
30. Schneider, T. R. (2002) Acta Crystallogr. Sect. D Biol. Crystallogr. 58, 195-208
31. Terwilliger, T. C. (2003) Methods Enzymol. 374, 22-37
32. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr. Sect. D Biol. Crystallogr. 53, 240-255
33. Davis, I. W., Murray, L. W., Richardson, J. S., and Richardson, D. C. (2004) Nucleic Acids Res. 32, W615-W619
34. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. Sect. D Biol. Crystallogr. 60, 2126-2132
35. Takahashi, H., Nakanishi, T., Kami, K., Arata, Y., and Shimada, I. (2000) Nat. Struct. Biol. 7, 220-223
36. Shimada, I. (2005) Methods Enzymol. 394, 483-506
37. Battiste, J. L., and Wagner, G. (2000) Biochemistry 39, 5355-5365
38. Holm, L., and Park, J. (2000) Bioinformatics (Oxf.) 16, 566-567
39. Burbelo, P. D., Drechsel, D., and Hall, A. (1995) J. Biol. Chem. 270, 29071-29074
40. Buck, M., Xu, W., and Rosen, M. K. (2004) J. Mol. Biol. 338, 271-285
41. Wennerberg, K., Forget, M. A., Ellerbroek, S. M., Arthur, W. T., Burridge, K., Settleman, J., Der, C. J., and Hansen, S. H. (2003) Curr. Biol. 13, 1106-1115
42. Tsubakimoto, K., Matsumoto, K., Abe, H., Ishii, J., Amano, M., Kaibuchi, K., and Endo, T. (1999) Oncogene 18, 2431-2440
43. Murphy, C., Saffrich, R., Olivo-Marin, J. C., Giner, A., Ansorge, W., Fotsis, T., and Zerial, M. (2001) Eur. J. Cell Biol. 80, 391-398
44. Fournier, A. E., Nakamura, F., Kawamoto, S., Goshima, Y., Kalb, R. G., and Strittmatter, S. M. (2000) J. Cell Biol. 149, 411-422
45. Love, C. A., Harlos, K., Mavaddat, N., Davis, S. J., Stuart, D. I., Jones, E. Y., and Esnouf, R. M. (2003) Nat. Struct. Biol. 10, 843-848
46. Antipenko, A., Himanen, J. P., van Leyen, K., Nardi-Dei, V., Lesniak, J., Barton, W. A., Rajashankar, K. R., Lu, M., Hoemme, C., Puschel, A. W., and Nikolov, D. B. (2003) Neuron 39, 589-598
47. Takahashi, T., and Strittmatter, S. M. (2001) Neuron 29, 429-439
48. Aspenstrom, P., Fransson, A., and Saras, J. (2004) Biochem. J. 377, 327-337
49. Swiercz, J. M., Kuner, R., Behrens, J., and Offermanns, S. (2002) Neuron 35, 51-63
50. Lovell, S. C., Davis, I. W., Arendall, W. B., III, de Bakker, P. I., Word, J. M., Prisant, M. G., Richardson, J. S., and Richardson, D. C. (2003) Proteins 50, 437-450