A point mutation in the ectodomain-transmembrane 2 interface eliminates the inhibitory effects of ethanol in P2X4 receptors

Journal of Neurochemistry

Volumn 112, Issue 1, 2010, Pages 307-317

  Popova, Maya ^a   Asatryan, Liana ^a   Ostrovskaya, Olga ^a   Wyatt, Letisha R ^a   Li, Kaixun ^a   Alkana, Ronald L ^a   Davies, Daryl L ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Alcohol; Ion channels; Purinergic P2X4 receptors; Sites of ethanol action; Two electrode voltage clamp; Xenopus oocytes

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALANINE; ALCOHOL; PURINERGIC P2X4 RECEPTOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CENTRAL NERVOUS SYSTEM; GENE EXPRESSION; MEMBRANE CURRENT; MOLECULAR WEIGHT; NEUROMODULATION; NONHUMAN; OOCYTE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; VOLTAGE CLAMP; WILD TYPE; XENOPUS LAEVIS;

ADENOSINE TRIPHOSPHATE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; FEMALE; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, PURINERGIC P2; XENOPUS LAEVIS;

EID: 71649102934     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06460.x     Document Type: Article

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