In benign Barrett's epithelial cells, acid exposure generates reactive oxygen species that cause DNA double-strand breaks

Cancer Research

Volumn 69, Issue 23, 2009, Pages 9083-9089

  Zhang, Hui Ying ^a   Hormi Carver, Kathy ^a   Zhang, Xi ^a   Spechler, Stuart J ^a   Souza, Rhonda F ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; ACETYLCYSTEINE; DOUBLE STRANDED DNA; HISTONE H2AX; REACTIVE OXYGEN METABOLITE;

ACIDIFICATION; ADULT; ARTICLE; BARRETT ESOPHAGUS; CASE REPORT; COMET ASSAY; CONTROLLED STUDY; DNA PROBE; DNA STRAND BREAKAGE; ENDOSCOPY; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; IN VIVO STUDY; MALE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUMOR BIOPSY; WESTERN BLOTTING;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; ACETYLCYSTEINE; BARRETT ESOPHAGUS; BIOPSY; CELL LINE; DNA BREAKS, DOUBLE-STRANDED; EPITHELIAL CELLS; HUMANS; HYDROCHLORIC ACID; REACTIVE OXYGEN SPECIES;

EID: 71549166650     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-2518     Document Type: Article

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