Acidic pH induces topoisomerase II-mediated DNA damage

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 9, 2003, Pages 5205-5210

  Xiao, Hai ^a   Li, Tsai Kun ^a   Yang, Jin Ming ^a,b   Liu, Leroy F ^a,b  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; NOREPIPODOPHYLLOTOXIN ETHYLIDENE BETA DEXTRO GLUCOSIDE; PROTEIN P53; SERINE; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; BARRETT ESOPHAGUS; CARCINOGENESIS; CARCINOGENICITY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; GENE MUTATION; HUMAN; HUMAN CELL; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TISSUE CULTURE;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ACIDS; ANIMALS; CARCINOGENS; CATALYSIS; DNA DAMAGE; DNA TOPOISOMERASES, TYPE II; FEMALE; HISTONES; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; MUTAGENESIS; PHOSPHORYLATION; PIPERAZINES; SERINE; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

ANIMALIA; ATAXIA; ATAXIA TELANGIECTASIA;

EID: 0037627683     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0935978100     Document Type: Article

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