A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 18, 2006, Pages 6970-6975

  Tuncman, G ^a   Erbay, E ^a   Hom, X ^a   De Vivo, I ^a,b   Campos, H ^a   Rimm, E B ^a,b   Hotamisligil, G S ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Adipocyte; FABP4; Macrophage; Metabolic syndrome; Triglyceride

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CHAPERONE; FATTY ACID BINDING PROTEIN; FATTY ACID BINDING PROTEIN AP2; LIPID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOCYTE; ALLELE; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DYSLIPIDEMIA; FEMALE; GENE LOCUS; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HOMOZYGOSITY; HUMAN; HUMAN CELL; HYPERTRIGLYCERIDEMIA; INSULIN RESISTANCE; ISCHEMIC HEART DISEASE; MALE; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PHENOTYPE; POPULATION GENETICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPOSE TISSUE; ADULT; ANIMALS; BASE SEQUENCE; CARDIOVASCULAR DISEASES; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; FATTY ACID-BINDING PROTEINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; HYPERTRIGLYCERIDEMIA; MIDDLE AGED; MOLECULAR SEQUENCE DATA; OBESITY; ODDS RATIO; PHENOTYPE; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); PROSPECTIVE STUDIES; PROTEIN BINDING; PROTEIN ISOFORMS; TRANSCRIPTION, GENETIC; TRIGLYCERIDES;

EID: 33646493482     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0602178103     Document Type: Article

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