메뉴 건너뛰기




Volumn 30, Issue 11, 2009, Pages 1841-1847

ELR+ CXC chemokines and oncogenic Ras-mediated tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR2; CXCL1 CHEMOKINE; INTERLEUKIN 6; INTERLEUKIN 8; MYC PROTEIN; RAS PROTEIN; SHORT HAIRPIN RNA; VASCULOTROPIN;

EID: 70849134402     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgp198     Document Type: Article
Times cited : (32)

References (41)
  • 1
    • 0024376173 scopus 로고
    • ras oncogenes in human cancer: A review
    • Bos,J.L. (1989) ras oncogenes in human cancer: A review. Cancer Res. 49, 4682-4689.
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 2
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • Downward,J. (2003) Targeting RAS signalling pathways in cancer therapy. Nat. Rev. Cancer, 3, 11-22.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 11-22
    • Downward, J.1
  • 3
    • 0032584108 scopus 로고    scopus 로고
    • Impact of oncogenes in tumor angiogenesis: Mutant K-ras up-regulation of vascular endothelial growth factor/ vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells
    • Okada,F. et al. (1998) Impact of oncogenes in tumor angiogenesis: mutant K-ras up-regulation of vascular endothelial growth factor/ vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells. Proc. Natl. Acad. Sci. USA, 95, 3609-3614.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3609-3614
    • Okada, F.1
  • 4
    • 0034650744 scopus 로고    scopus 로고
    • Oncogenes and tumor angiogenesis: Differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts
    • Rak,J. et al. (2000) Oncogenes and tumor angiogenesis: differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts. Cancer Res., 60, 490-498.
    • (2000) Cancer Res , vol.60 , pp. 490-498
    • Rak, J.1
  • 5
    • 7944223098 scopus 로고    scopus 로고
    • Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis
    • Sparmann,A. et al. (2004) Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis. Cancer Cell 6, 447-458.
    • (2004) Cancer Cell , vol.6 , pp. 447-458
    • Sparmann, A.1
  • 6
    • 9444267059 scopus 로고    scopus 로고
    • The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor
    • Ahuja,S.K. et al. (1996) The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor. J. Biol. Chem., 271, 20545-20550.
    • (1996) J. Biol. Chem , vol.271 , pp. 20545-20550
    • Ahuja, S.K.1
  • 7
    • 0036781172 scopus 로고    scopus 로고
    • Cytokine regulation of constitutive production of interleukin-8 and -6 by human pancreatic cancer cell lines and serum cytokine concentrations in patients with pancreatic cancer
    • Wigmore,S.J. et al. (2002) Cytokine regulation of constitutive production of interleukin-8 and -6 by human pancreatic cancer cell lines and serum cytokine concentrations in patients with pancreatic cancer. Int. J. Oncol., 21, 881-886.
    • (2002) Int. J. Oncol , vol.21 , pp. 881-886
    • Wigmore, S.J.1
  • 8
    • 33750089043 scopus 로고    scopus 로고
    • Serum vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8) levels in small cell lung cancer
    • Tas,F. et al. (2006) Serum vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8) levels in small cell lung cancer. Cancer Invest., 24, 492-496.
    • (2006) Cancer Invest , vol.24 , pp. 492-496
    • Tas, F.1
  • 9
    • 33644841344 scopus 로고    scopus 로고
    • Decline in angiogenic factors, such as interleukin-8, indicates response to chemotherapy of metastatic melanoma
    • Brennecke,S. et al. (2005) Decline in angiogenic factors, such as interleukin-8, indicates response to chemotherapy of metastatic melanoma. Melanoma Res., 15, 515-522.
    • (2005) Melanoma Res , vol.15 , pp. 515-522
    • Brennecke, S.1
  • 10
    • 34247877774 scopus 로고    scopus 로고
    • Serum cytokine profiling as a diagnostic and prognostic tool in ovarian cancer: A potential role for interleukin 7
    • Lambeck,A.J. et al. (2007) Serum cytokine profiling as a diagnostic and prognostic tool in ovarian cancer: A potential role for interleukin 7. Clin. Cancer Res., 13, 2385-2391.
    • (2007) Clin. Cancer Res , vol.13 , pp. 2385-2391
    • Lambeck, A.J.1
  • 11
    • 33745890935 scopus 로고    scopus 로고
    • Circulating IL-8 and anti-IL-8 autoantibody in patients with ovarian cancer
    • Lokshin,A.E. et al. (2006) Circulating IL-8 and anti-IL-8 autoantibody in patients with ovarian cancer. Gynecol. Oncol., 102, 244-251.
    • (2006) Gynecol. Oncol , vol.102 , pp. 244-251
    • Lokshin, A.E.1
  • 12
    • 6344241445 scopus 로고    scopus 로고
    • Serum interleukin-8 is elevated in men with prostate cancer and bone metastases
    • Lehrer,S. et al. (2004) Serum interleukin-8 is elevated in men with prostate cancer and bone metastases. Technol. Cancer Res. Treat. 3, 411.
    • (2004) Technol. Cancer Res. Treat , vol.3 , pp. 411
    • Lehrer, S.1
  • 13
    • 0037372374 scopus 로고    scopus 로고
    • Elevation of cytokine levels in cachectic patients with prostate carcinoma
    • Pfitzenmaier,J. et al. (2003) Elevation of cytokine levels in cachectic patients with prostate carcinoma. Cancer, 97, 1211-1216.
    • (2003) Cancer , vol.97 , pp. 1211-1216
    • Pfitzenmaier, J.1
  • 14
    • 34447506658 scopus 로고    scopus 로고
    • Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis
    • Ancrile,B. et al. (2007) Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis. Genes Dev., 21, 1714-1719.
    • (2007) Genes Dev , vol.21 , pp. 1714-1719
    • Ancrile, B.1
  • 15
    • 40849114627 scopus 로고    scopus 로고
    • Oncogenic ras-induced expression of cytokines: A new target of anti-cancer therapeutics
    • Ancrile,B.B. et al. (2008) Oncogenic ras-induced expression of cytokines: A new target of anti-cancer therapeutics. Mol. Interv., 8, 22-27.
    • (2008) Mol. Interv , vol.8 , pp. 22-27
    • Ancrile, B.B.1
  • 16
    • 0142250392 scopus 로고    scopus 로고
    • Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: A review of the rationale and clinical evidence
    • Trikha,M. et al. (2003) Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: A review of the rationale and clinical evidence. Clin. Cancer Res., 9, 4653-4665.
    • (2003) Clin. Cancer Res , vol.9 , pp. 4653-4665
    • Trikha, M.1
  • 17
    • 12144287282 scopus 로고    scopus 로고
    • A genetically defined model for human ovarian cancer
    • Liu,J. et al. (2004) A genetically defined model for human ovarian cancer. Cancer Res., 64, 1655-1663.
    • (2004) Cancer Res , vol.64 , pp. 1655-1663
    • Liu, J.1
  • 18
    • 33750798741 scopus 로고    scopus 로고
    • The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis
    • Yang,G. et al. (2006) The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis. Proc. Natl. Acad. Sci. USA, 103, 16472-16477.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16472-16477
    • Yang, G.1
  • 19
    • 0030022829 scopus 로고    scopus 로고
    • CXC chemokines bind to unique sets of selectivity determinants that can function independently and are broadly distributed on multiple domains of human interleukin-8 receptor B. Determinants of high affinity binding and receptor activation are distinct
    • Ahuja,S.K. et al. (1996) CXC chemokines bind to unique sets of selectivity determinants that can function independently and are broadly distributed on multiple domains of human interleukin-8 receptor B. Determinants of high affinity binding and receptor activation are distinct. J. Biol. Chem., 271, 225-232.
    • (1996) J. Biol. Chem , vol.271 , pp. 225-232
    • Ahuja, S.K.1
  • 20
    • 34247855761 scopus 로고    scopus 로고
    • Chemokine: Receptor structure, interactions, and antagonism
    • Allen,S.J. et al. (2007) Chemokine: Receptor structure, interactions, and antagonism. Annu. Rev. Immunol., 25, 787-820.
    • (2007) Annu. Rev. Immunol , vol.25 , pp. 787-820
    • Allen, S.J.1
  • 21
    • 0034080318 scopus 로고    scopus 로고
    • The biology of chemokines and their receptors
    • Rossi,D. et al. (2000) The biology of chemokines and their receptors. Annu. Rev. Immunol., 18, 217-242.
    • (2000) Annu. Rev. Immunol , vol.18 , pp. 217-242
    • Rossi, D.1
  • 22
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens,L.M. et al. (2002) Inflammation and cancer. Nature, 420, 860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1
  • 23
    • 0037443760 scopus 로고    scopus 로고
    • IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis
    • Li,A. et al. (2003) IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J. Immunol., 170, 3369-3376.
    • (2003) J. Immunol , vol.170 , pp. 3369-3376
    • Li, A.1
  • 24
    • 27644556527 scopus 로고    scopus 로고
    • Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance
    • Lim,K.H. et al. (2005) Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance. Cancer Cell, 8, 381-392.
    • (2005) Cancer Cell , vol.8 , pp. 381-392
    • Lim, K.H.1
  • 25
    • 27544453375 scopus 로고    scopus 로고
    • A network of genetic events sufficient to convert normal human cells to a tumorigenic state
    • Kendall,S.D. et al. (2005) A network of genetic events sufficient to convert normal human cells to a tumorigenic state. Cancer Res., 65, 9824-9828.
    • (2005) Cancer Res , vol.65 , pp. 9824-9828
    • Kendall, S.D.1
  • 26
    • 2342526543 scopus 로고    scopus 로고
    • A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
    • Yeh,E. et al. (2004) A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat. Cell Biol., 6, 308-318.
    • (2004) Nat. Cell Biol , vol.6 , pp. 308-318
    • Yeh, E.1
  • 27
    • 19644366513 scopus 로고    scopus 로고
    • Genetic modeling of human rhabdomyosarcoma
    • Linardic,C.M. et al. (2005) Genetic modeling of human rhabdomyosarcoma. Cancer Res., 65, 4490-4495.
    • (2005) Cancer Res , vol.65 , pp. 4490-4495
    • Linardic, C.M.1
  • 28
    • 0037102561 scopus 로고    scopus 로고
    • Distinct requirements for Ras oncogenesis in human versus mouse cells
    • Hamad,N.M. et al. (2002) Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes Dev., 16, 2045-2057.
    • (2002) Genes Dev , vol.16 , pp. 2045-2057
    • Hamad, N.M.1
  • 29
    • 0033614998 scopus 로고    scopus 로고
    • Creation of human tumour cells with defined genetic elements
    • Hahn,W.C. et al. (1999) Creation of human tumour cells with defined genetic elements. Nature, 400, 464-468.
    • (1999) Nature , vol.400 , pp. 464-468
    • Hahn, W.C.1
  • 30
    • 27644525734 scopus 로고    scopus 로고
    • A genetically defined normal human somatic cell system to study ras oncogenesis in vivo and in vitro
    • O'Hayer,K. et al. (2006) A genetically defined normal human somatic cell system to study ras oncogenesis in vivo and in vitro. Methods Enzymol., 407, 637-647.
    • (2006) Methods Enzymol , vol.407 , pp. 637-647
    • O'Hayer, K.1
  • 31
    • 33750798741 scopus 로고    scopus 로고
    • The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis
    • Yang,G. et al. (2006) The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis. Proc. Natl. Acad. Sci. USA, 103, 16472-16477.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16472-16477
    • Yang, G.1
  • 32
    • 0035252894 scopus 로고    scopus 로고
    • Protein phosphatase 2A: A highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
    • Janssens,V. et al. (2001) Protein phosphatase 2A: A highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochem. J., 353, 417-439.
    • (2001) Biochem. J , vol.353 , pp. 417-439
    • Janssens, V.1
  • 33
    • 33748331308 scopus 로고    scopus 로고
    • The mighty mouse: Genetically engineered mouse models in cancer drug development
    • Sharpless,N.E. et al. (2006) The mighty mouse: Genetically engineered mouse models in cancer drug development. Nat. Rev. Drug Discov., 5, 741-754.
    • (2006) Nat. Rev. Drug Discov , vol.5 , pp. 741-754
    • Sharpless, N.E.1
  • 34
    • 0022527161 scopus 로고
    • Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
    • Quintanilla,M. et al. (1986) Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature, 322, 78-80.
    • (1986) Nature , vol.322 , pp. 78-80
    • Quintanilla, M.1
  • 35
    • 0028067339 scopus 로고
    • Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog
    • Cacalano,G. et al. (1994) Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog. Science, 265, 682-684.
    • (1994) Science , vol.265 , pp. 682-684
    • Cacalano, G.1
  • 36
    • 33646255924 scopus 로고    scopus 로고
    • High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras
    • Wislez,M. et al. (2006) High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras. Cancer Res., 66, 4198-4207.
    • (2006) Cancer Res , vol.66 , pp. 4198-4207
    • Wislez, M.1
  • 37
    • 10044261013 scopus 로고    scopus 로고
    • Cytokines in pancreatic carcinoma: Correlation with phenotypic characteristics and prognosis
    • Ebrahimi,B. et al. (2004) Cytokines in pancreatic carcinoma: correlation with phenotypic characteristics and prognosis. Cancer, 101, 2727-2736.
    • (2004) Cancer , vol.101 , pp. 2727-2736
    • Ebrahimi, B.1
  • 38
    • 0033614962 scopus 로고    scopus 로고
    • Essential role for oncogenic Ras in tumour maintenance
    • Chin,L. et al. (1999) Essential role for oncogenic Ras in tumour maintenance. Nature, 400, 468-472.
    • (1999) Nature , vol.400 , pp. 468-472
    • Chin, L.1
  • 39
    • 0842303173 scopus 로고    scopus 로고
    • Reversibility of oncogene-induced cancer
    • Felsher,D.W. (2004) Reversibility of oncogene-induced cancer. Curr. Opin. Genet. Dev., 14, 37-42.
    • (2004) Curr. Opin. Genet. Dev , vol.14 , pp. 37-42
    • Felsher, D.W.1
  • 40
    • 28844509531 scopus 로고    scopus 로고
    • K-ras as a target for cancer therapy
    • Friday,B.B. et al. (2005) K-ras as a target for cancer therapy. Biochim. Biophys. Acta, 1756, 127-144.
    • (2005) Biochim. Biophys. Acta , vol.1756 , pp. 127-144
    • Friday, B.B.1
  • 41
    • 27144449009 scopus 로고    scopus 로고
    • Monoclonal antibody therapy of cancer
    • Adams,G.P. et al. (2005) Monoclonal antibody therapy of cancer. Nat. Biotechnol., 23, 1147-1157.
    • (2005) Nat. Biotechnol , vol.23 , pp. 1147-1157
    • Adams, G.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.