Genetic modeling of human rhabdomyosarcoma

Cancer Research

Volumn 65, Issue 11, 2005, Pages 4490-4495

  Linardic, Corinne M ^a   Downie, Diane L ^a   Qualman, Stephen ^b   Bentley, Rex C ^a   Counter, Christopher M ^a  

^a DUKE UNIVERSITY   (United States)

^b THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RAS PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INVASION; CARCINOGENICITY; CELL DIFFERENTIATION; CELL TYPE; CONTROLLED STUDY; EMBRYONAL RHABDOMYOSARCOMA; GENETIC HETEROGENEITY; GENETIC MODEL; GENETIC TRANSFORMATION; HISTOLOGY; HUMAN; HUMAN CELL; METASTASIS; MOUSE; MUSCLE CELL; MYOBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RHABDOMYOSARCOMA; SKELETAL MUSCLE;

ADOLESCENT; ANIMALS; ANTIGENS, VIRAL, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DNA-BINDING PROTEINS; GENES, RAS; HUMANS; MESENCHYMAL STEM CELLS; MICE; MICE, SCID; MUSCLE, SKELETAL; NEOPLASM TRANSPLANTATION; RHABDOMYOSARCOMA; TELOMERASE; TRANSPLANTATION, HETEROLOGOUS;

EID: 19644366513     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-3194     Document Type: Article

References (31)

1. Meyer WH, Spunt SL. Soft tissue sarcomas of childhood. Cancer Treat Rev 2004;30:269-80.
2. Merlino G, Helman LJ. Rhabdomyosarcoma: working out the pathways. Oncogene 1999;18:5340-8.
3. Nanni P, Nicoletti G, De Giovanni C. et al. Development of rhabdomyosarcoma in HER-2/neu transgenic p53 mutant mice. Cancer Res 2003;63:2728-32.
4. Sharp R, Redo JA, Jhappnn C, et al. Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis. Nat Med 2002; 8:1276-80.
5. Keller C, Arenklel BR, Coffin CM, El Bardeesy N, DePinho RA, Capecchi MR Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of lnk4a/ARF and Trp53 loss of function. Genes Dev 2004; 18:2614-26.
6. Ghebranious N, Donehower LA. Mouse models in tumor suppression. Oncogene 1998;17:3385-400.
7. Hamad NM, Elconin JH, Karnoub AE, et al. Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes Dev 2002;16:2045-57.
8. Takahashi Y, Oda Y, Kawaguchi K, et al. Altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma. Mod Pathol 2004;17:660-9.
9. Gordon AT, Brinkschmidt C, Anderson J, et al, A novel and consistent amplicon at 13q31 associated with alveolar rhabdomyosarcoma. Genes Chromosomes Cancer 2000;28:220-6.
10. Birch JM, Hartley AL, Blair V, et al. Cancer In the families of children with soft tissue sarcoma. Cancer 1990;66:2239-48.
11. Maelandsmo GM, Berner JM, Florenes VA, et al. Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas: relationship to amplification and mRNA levels of CDK4 and CCND1. Br J Cancer 1995;72:393-8.
12. Williamson D, Lu YJ, Gordon T, et al. Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype. J Clin Oncol 2005;23:880-8.
13. Boon K, Caron HN, van Asperen R, et al. N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO J 2001;20:1383-93.
14. Kleideiter E, Schwab M, Friedrich U, Koscielniak E, Schafer BW, Klotz U. Telomerase activity in cell lines of pediatric soft tissue sarcomas. Pediatr Res 2003;34:718-23.
15. Terasaki T, Kyo S, Takakura M, et al. Analysis of telomerase activity and telomere length in bone and soft tissue tumors. Oncol Rep 2004;11:1307-11.
16. Henson JD, Hannay JA, McCarthy SW, et al. A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas. Clin Cancer Res 2005;11:217-25.
17. Bos JL, Ras oncogenes in human cancer: a review. Cancer Res 1989;49:4682-9.
18. Wilke W, Maillet M, Robinson R. H-ras-1 point mutations in soft tissue sarcomas. Mod Pathol 1993;6: 129-32.
19. Yoo J, Robinson RA. H-ras and K-ras mutations in soft tissue sarcoma: comparative studies of sarcomas from Korean and American patients. Cancer 1999;86:58-63.
20. Reed N, Gutmann DH. Tumorigenesis in neurofibromatosis: new insights and potential therapies. Trends Mol Med 2001;7:157-62.
21. Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW, Weinberg RA. Creation of human tumour cells with defined genetic elements. Nature 1999; 400:464-8.
22. Yeh E, Cunningham M, Arnold H, et al. A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat Cell Biol 2004;6:308-18.
23. Collins K, Mitchell JR. Telomerase in the human organism. Oncogene 2002;21:564-79.
24. Linardic CM, Jayadev S, Hannun YA. Activation of the sphingomyelin cycle by brefeldln A: effects of brefeldin A on differentiation and implications for a role for ceramide In regulation of protein trafficking, Cell Growth Differ 1996;7:765-74.
25. Grounds MD, White JD, Rosenthal N, Bogoyevitch MA. The role of stem cells in skeletal and cardiac muscle repair. J Histochem Cytochem 2002;50:589-610.
26. Elenbaas B, Spirio L, Koerner F, et al. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev 2001;15: 50-65.
27. Seigneurin-Venin S, Bernard V, Moisset PA, et al. Transplantation of normal and DMD myoblasts expressing the telomerase gene in SCID mice. Biochem Biophys Res Commun 2000;272:362-9.
28. Bringold F, Serrano M. Tumor suppressors and oncogenes in cellular senescence. Exp Gerontol 2000; 35:317-29.
29. Mouly V, Edom F, Decary S, Vicart P, Barbert JP, Butler-Browne GS. SV40 large T antigen interferes with adult myosin heavy chain expression, but not with differentiation of human satellite cells. Exp Cell Res 1996;225:268-76.
30. Tiffin N, Williams RD, Shipley J, Pritchard-Jones K. PAX7 expression in embryonal rhabdomyosarcoma suggests an origin in muscle satellite cells. Br J Cancer 2003;89:327-32.
31. Quinn KA, Treston AM, Unsworth EJ, et al. Insulin-like growth factor expression in human cancer cell lines. J Biol Chem 1996;271:11477-83.