Inter-individual difference determinant of prednisolone pharmacokinetics for Japanese renal transplant recipients in the maintenance stage

Xenobiotica

Volumn 39, Issue 12, 2009, Pages 939-945

  Miura, M ^a   Inoue, K ^a   Kagaya, H ^a   Saito, M ^b   Habuchi, T ^b   Satoh, S ^b  

^a AKITA UNIVERSITY HOSPITAL   (Japan)

^b AKITA UNIVERSITY   (Japan)

Author keywords

Glucocorticoid receptor; Polymorphism; Prednisolone; Pregnane X receptor

Indexed keywords

CYTOCHROME P450 3A5; GLUCOCORTICOID RECEPTOR; METHYLPREDNISOLONE; MULTIDRUG RESISTANCE PROTEIN 1; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; PREDNISOLONE; PROTEIN BCL 2; PROTEIN NR1 I2; PROTEIN NR3 C1; STEROID; TACROLIMUS; UNCLASSIFIED DRUG;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG MEGADOSE; FEMALE; GENE FREQUENCY; GENETIC VARIABILITY; GENOTYPE; GRAFT RECIPIENT; GRAFT REJECTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; JAPANESE; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; PHARMACOLOGICAL PARAMETERS; PROMOTER REGION; SINGLE DRUG DOSE; SINGLE NUCLEOTIDE POLYMORPHISM; TIME TO MAXIMUM PLASMA CONCENTRATION; TRANSACTIVATION;

ADULT; AGED; AREA UNDER CURVE; ASIAN CONTINENTAL ANCESTRY GROUP; GENOTYPE; HUMANS; KIDNEY TRANSPLANTATION; MIDDLE AGED; POLYMORPHISM, GENETIC; PREDNISOLONE;

EID: 70849093330     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498250903294361     Document Type: Article

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