Kainic acid-induced f-344 rat model of Mesial temporal lobe epilepsy: gene expression and canonical Pathways

Toxicologic Pathology

Volumn 37, Issue 6, 2009, Pages 776-789

  Sharma, Alok K ^a,d   Searfoss, George H ^c   Reams, Rachel Y ^b   Jordan, William H ^c   Snyder, Paul W ^d   Chiang, Alan Y ^c   Jolly, Robert A ^c   Ryan, Timothy P ^c  

^a 206 Carnegie Center   (United States)

^b Department of Molecular and Anatomical Imaging   (United States)

^c ELI LILLY AND COMPANY   (United States)

^d PURDUE UNIVERSITY   (United States)

Author keywords

Animal models; Kainic acid; Mesial temporal lobe epilepsy; Toxicogenomics; Toxicologic pathology

Indexed keywords

ACTIN; BIOLOGICAL MARKER; BRAIN DERIVED NEUROTROPHIC FACTOR; CALPAIN 1; CASPASE 3; CYCLOOXYGENASE 2; CYTOCHROME C; DIAZEPAM; EPHRIN RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 6; KAINIC ACID; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUROTROPHIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN BAX; PROTEIN CDC42; PROTEIN TYROSINE KINASE; RAC1 PROTEIN; RETINOID X RECEPTOR ALPHA; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROL GROUP; CONTROLLED STUDY; DISEASE COURSE; DISEASE MARKER; EPILEPTIC STATE; EXPERIMENTAL MODEL; EXPERIMENTAL RAT; FISCHER 344 RAT; GENE CONTROL; GENE EXPRESSION; HIPPOCAMPUS; HISTOPATHOLOGY; IMMUNE RESPONSE; INFLAMMATION; LONG TERM DEPRESSION; MALE; MESIAL TEMPORAL LOBE EPILEPSY; MOLECULAR MECHANICS; NERVE CELL PLASTICITY; NERVE DEGENERATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; TEMPORAL LOBE EPILEPSY; UBIQUITINATION; UPREGULATION;

ANIMALS; BEHAVIOR, ANIMAL; CLUSTER ANALYSIS; DISEASE MODELS, ANIMAL; EPILEPSY, TEMPORAL LOBE; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HISTOCYTOCHEMISTRY; INFLAMMATION; KAINIC ACID; MALE; NERVE DEGENERATION; NEURONAL PLASTICITY; RATS; RATS, INBRED F344; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; TOXICOGENETICS;

ANIMALIA; RATTUS;

EID: 70649090030     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623309344202     Document Type: Article

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