TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons

Genes and Development

Volumn 10, Issue 22, 1996, Pages 2849-2858

  Minichiello, Liliana ^a   Klein, Rüdiger ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

apoptosis; cerebellum; dentate gyrus; hippocampus; Neurotrophins; receptor tyrosine kinase; Trk

Indexed keywords

NEUROTROPHIN RECEPTOR; PROTEIN TYROSINE KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CEREBELLUM; CONTROLLED STUDY; DENTATE GYRUS; GRANULE CELL; HIPPOCAMPUS; MOSSY FIBER; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL;

ANIMALIA; VERTEBRATA;

EID: 0029807584     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.22.2849     Document Type: Article

References (55)

1. Altman, J. 1982. Morphological development of the rat cerebellum and some of its mechanisms. In The cerebellum-New vistas (ed. S.L. Palay and V. Chan-Palay), pp. 8-46. Springer-Verlag, Berlin, Germany.
2. Arenas, E. and H.J. Persson. 1994. Neurotrophin-3 prevents the death of adult central noradrenergic neurons in vivo. Nature 367: 368-371.
3. Baptista, C.A., M.E. Hatten, R. Blazeski, and C.A. Mason. 1994. Cell-cell interactions influence survival and differentiation of purified Purkinje cells in vitro. Nature 12: 243-260.
4. Barbacid, M. 1995. Neurotrophic factors and their receptors. Curr. Opin. Cell Biol. 7: 148-155.
5. Bengzon, J., Z. Kokaia, P. Ernfors, M. Kokaia, G. Leanza, O.G. Nilsson, H. Persson, and O. Lindvall. 1993. Regulation of neurotrophin and trkA, trkB and trkC tyrosine kinase receptor messenger RNA expression in kindling. Neuroscience 53: 433-446.
6. Bianchi, L.M., J.C. Conover, B. Fritzsch, T. DeChiara, R.M. Lindsay, and G.D. Yancopoulos. 1996. Degeneration of vestibular neurons in late embryogenesis of both heterozygous and homozygous BDNF null mutant mice. Development 122: 1965-1973.
7. Cabelli, R.J., A. Hohn, and C.I. Shatz. 1995. Inhibition of ocular dominance column formation by infusion of NT-4/5 or BDNF. Science 267: 1662-1665.
8. Celio, M.R. 1990. Calbindin D-28K and parvalbumin in the rat nervous system. Neuroscience 35: 375-475.
9. Cohen-Cory, S. and S.E. Fraser. 1995. Effects of brain-derived neurotrophic factor on optic axon branching and remodeling in vivo. Nature 378: 192-196.
10. Collazo, D., H. Takahashi, and R.D. McKay. 1992. Cellular targets and trophic functions of neurotrophin-3 in the developing rat hippocampus. Neuron 9: 643-656.
11. Crowley, C., S.D. Spencer, M.C. Nishimura, K.S. Chen, S. Pitts-Meek, M.P. Armanini, L.H. Ling, S.B. McMahon, D.L. Shelton, A.D. Levinson, and H.S. Phillis. 1994. Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell 76: 1001-1011.
12. Davies, A.M. 1994a. Role of neurotrophins in the developing nervous system. J. Neurobiol. 25: 1334-1348.
13. _. 1994b. Switching neurotrophin dependence. Curr. Biol. 4: 273-276.
14. Davies, A.M., L. Munichiello, and R. Klein. 1995. Developmental changes in NT3 signalling via TrkA and TrkB in embryonic neurons. EMBO J. 14: 4482-4489.
15. Eide, F.F., D.H. Lowenstein, and L.F. Reichardt. 1993. Neurotrophins and their receptors - Current concepts and implications for neurologic disease. Exp. Neurol. 121: 200-214.
16. Ernfors, P., T. Van De Water, J. Lorin, and R. Jaenisch. 1995. Complementary roles for BDNF and NT3 in vestibular and auditory development. Neuron 14: 1153-1164.
17. Farinas, I. and L.F. Reichardt. 1996. Neurotrophic factors and their receptors: Implications of genetic studies. Semin. Neurosci. (in press).
18. Farinas, I., K. Jones, C. Backus, X.-Y. Wang, and L. Reichardt. 1994. Severe sensory and sympathetic deficits in mice lacking neurotrophin-3. Nature 369: 658-661.
19. Gao, W.Q., J.L. Zheng, and M. Karihaloo. 1995. Neurotrophin-4/5 (NT4/5) and brain-derived neurotrophic factor (BDNF) act at later stages of cerebellar granule cell differentiation. J. Neurosci. 15: 2656-2667.
20. Gavrielli, Y., Y. Sherman, and S.A. Ben-Sasson. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119: 493-501.
21. Götz, R., R. Kostner, C Winkler, F. Raulf, F. Lottspeich, M. Schartl, and H. Thoenen. 1994. Neurotrophin-6 is a new member of the nerve growth factor family. Nature 372: 266-269.
22. Gould, E., C.S. Woolley, and B.S. McEwen. 1991. Naturally occurring cell death in the developing dentate gyrus of the rat. J. Comp. Neurol. 304: 408-418.
23. Henderson, C.E. 1996. Role of neurotrophic factors in neuronal development. Curr. Opin. Neurobiol. 6: 64-70.
24. Henderson, C.E., W. Camu, C. Mettling, A. Gouin, K. Poulsen, M. Karlaloo, I. Rullamas, T. Evans, S.B. McMahon, M.P. Armanini, L. Berkemeier, H.S. Phillips, and A. Rosenthal. 1993. Neurotrophins promote motor neuron survival and are present in embryonic limb bud. Nature 363: 266-270.
25. Ip, N., Y. Li, G.D. Yancopoulos, and R.M. Lindsay. 1993. Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF. J. Neurosci. 13: 3394-3405.
26. Isackson, P.J. 1995. Trophic factor response to neuronal stimuli or injury. Curr. Opin. Neurobiol. 5: 350-357.
27. Jones, K., I. Farinas, C. Backus, and L. Reichardt. 1994. Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell 76: 989-999.
28. Rang, H. and E.M. Schuman. 1995. Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science 267: 1658-1663.
29. Klein, R. 1994. Role of neurotrophins in mouse neuronal development. FASEB J. 8: 738-744.
30. Klein, R., D. Martin-Zanca, M. Barbacid, and L.F. Parada. 1990. Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system. Development 109: 845-850.
31. Klein, R., R.J. Smeyne, W. Wurst, L.K. Long, B.A. Auerbach, A.L. Joyner, and M. Barbacid. 1993. Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death. Cell 75: 113-122.
32. Klein, R., I. Silos-Santiago, R.J. Smeyne, S.A. Lira, R. Brambilla, S. Bryant, L. Zhang, W.D. Snider, and M. Barbacid. 1994. Targeted disruption of trkC, the neurotrophin-3 receptor gene, eliminates la muscle afferents and results in loss of proprioception. Nature 368: 249-251.
33. Kosaka, T. and K. Hama. 1986. Three-dimensional structure of astrocytes in the rat dentate gyrus. J. Comp. Neurol. 249: 242-260.
34. Lamballe, F., R.J. Smeyne, and M. Barbacid. 1994. Developmental expression of trkC, the neurotrophin-3 receptor, in the mammalian nervous system. J. Neurosci. 14: 14-28.
35. Leingärtner, A., C.-P. Heisenberg, R. Kolbeck, H. Thoenen, and D. Lindholm. 1994. Brain-derived neurotrophic factor increases neurotrophin-3 expression in cerebellar granule neurons. J. Biol. Chem. 269: 828-830.
36. Lewin, G.R. and Y.-A. Barde. 1996. Physiology of the neurotrophins. Annu. Rev. Neurosci. 19: 289-317.
37. Lindholm, D., E. Castrén, P. Tsoulfas, R. Kolbeck, M. Berzaghi da Penha, A. Leingärtner, C-P. Heisenberg, L. Tessarollo, L.F. Parada, and H. Thoenen. 1993. Neurotrophin-3 induced by tri-iodothyronine in cerebellar granule cells promotes Purkinje cell differentiation. J. Cell Biol. 122: 443-45.
38. Lindvall, O., Z. Kokaia, J. Bengzon, E. Elmer, and M. Kokaia. 1994. Neurotrophins and brain insults. Trends Neurosci. 17: 490-496.
39. Lowenstein, D.H. and L. Arsenault. 1996. The effects of growth factors on the survival and differentiation of cultured dentate gyrus neurons. J. Neurosci. 16: 1759-1769.
40. Minichiello, L., F. Piehl, E. Vazquez, T. Schimmang, T. Hökfelt, J. Represa, and R. Klein. 1995. Differential effects of combined trk receptor mutations on dorsal root ganglion and inner ear sensory neurons. Development 121: 4067-4075.
41. Ohsawa, F., H.R. Widmer, B. Knusel, T.L. Denton, and F. Hefti. 1993. Response of embryonic rat hippocampal neurons in culture to neurotrophin-3, brain-derived neurotrophic factor and basic fibroblast growth factor. Neuroscience 57: 67-77.
42. Olivo, J.-C., J.-C. Izpisua-Belmonte, C. Tickle, C Boulin, and D. Duboule. 1993. Reconstruction from serial sections: A tool for developmental biology. Application to Hox genes expression in chicken wing buds. Bioimaging 1: 151-158.
43. Oppenheim, R.W., Y. Qin-Wei, D. Prevette, and Q. Yan. 1992. Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death. Nature 360: 755-757.
44. Piñon, L.G.P., L. Minichiello, R. Klein, and A.M. Davies. 1996. Timing of neuronal death in trkA, trkB, and trkC mutant embryos demonstrates neurotrophin switching in developing trigeminal neurons. Development 122: 3255-3261.
45. Richmann, M., D.G. Amaral, and W.M. Cowan. 1987. Organization of radial glial cells during the development of the rat dentate gyrus. J. Comp. Neurol. 264: 449-479.
46. Schimmang, T., L. Minichiello, E. Vazquez, I. San Jose, F. Giraldez, R. Klein, and J. Represa. 1995. Developing inner ear sensory neurons require TrkB and TrkC receptors for innervation of their peripheral targets. Development 121: 3381-3391.
47. Segal, R.A, H. Takahashi, and R.D.G. McKay. 1992. Changes in neurotrophin responsiveness during the development of cerebellar granule neurons. Neuron 9: 1041-1052.
48. Segal, R.A., S.L. Pomeroy, and C.D. Stiles. 1995. Axonal growth and fasciculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells. J. Neurosci. 15: 4970-4981.
49. Sendtner M., B. Holtmannn, R. Kolbeck, H. Thoenen, and Y.-A. Barde. 1992. Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 360: 757-759.
50. Smeyne, R.J., R. Klein, A. Schnapp, L.K. Long, S. Bryant, A. Lewin, S.A. Lira, and M. Barbacid. 1994. Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGD receptor gene. Nature 368: 246-249.
51. Snider, W. 1994. Function of the neurotrophins during nervous system development: What the knockouts are teaching us. Cell 77: 627-638.
52. Tessarollo, L., P. Tsoulfas, D. Martin-Zanca, D.J. Gilbert, ,N.A. Jenkins, N.C. Copeland, and L.F. Parada. 1993. trkC, a receptor of neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues. Development 118: 463-475.
53. Thoenen, H. 1995. Neurotrophins and neuronal plasticity. Science 270: 593-598.
54. Yan, Q., J. Elliott, and W.D Snider. 1992. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature 360: 753-755.
55. Zalutsky, R.A. and R.A. Nicoll. 1990. Comparison of two forms of long-term potentiation in single hippocampal slices. Science 248: 1619-1624.