Prostaglandin E2 produced by late induced COX-2 stimulates hippocampal neuron loss after seizure in the CA3 region

Neuroscience Research

Volumn 56, Issue 1, 2006, Pages 103-110

  Takemiya, Takako ^a,b   Maehara, Michiyo ^b   Matsumura, Kiyoshi ^c   Yasuda, Shin ^a   Sugiura, Hiroko ^a   Yamagata, Kanato ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c OSAKA INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

CA3 region; COX 2; COX 2 knockout mouse; Hippocampal neuron death; Kainic acid; Prostaglandin E2; Seizure; Selective COX 2 inhibitor

Indexed keywords

CYCLOOXYGENASE 2; KAINIC ACID; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E2; AMINO ACID RECEPTOR STIMULATING AGENT; N-(2-CYCLOHEXYLOXY-4-NITROPHENYL)METHANESULFONAMIDE; NITROBENZENE DERIVATIVE; PROSTAGLANDIN SYNTHASE INHIBITOR; SULFONAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL DEATH; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INDUCTION; ENZYME INHIBITION; HIPPOCAMPUS; KNOCKOUT MOUSE; MALE; MICROINJECTION; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEIZURE; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; CYTOLOGY; DRUG EFFECT; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; WISTAR RAT;

ANIMALS; CELL DEATH; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; ENZYME INDUCTION; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; KAINIC ACID; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROINJECTIONS; NEURONS; NITROBENZENES; RATS; RATS, WISTAR; SEIZURES; SULFONAMIDES;

EID: 33747883648     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2006.06.003     Document Type: Article

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