Up-regulation of CYP1A1 by rutaecarpine is dependent on aryl hydrocarbon receptor and calcium

Toxicology

Volumn 266, Issue 1-3, 2009, Pages 38-47

  Han, Eun Hee ^a,c   Kim, Hyung Gyun ^a,c   Im, Ji Hye ^a,c   Jeong, Tae Cheon ^b   Jeong, Hye Gwang ^a  

^a Chungnam National University   (South Korea)

^b Yeungnam University   (South Korea)

^c Chosun University   (South Korea)

Author keywords

Aryl hydrocarbon receptor; Calcium; CYP1A1; Rutaecarpine

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM ION; CH 223191; CYTOCHROME P450 1A1; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; MESSENGER RNA; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; RECEPTOR BLOCKING AGENT; RUTAECARPINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DRUG CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE EXPRESSION; HEPATOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; XENOBIOTIC RESPONSE ELEMENT;

ANIMALS; AZO COMPOUNDS; BINDING SITES; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES; CELL LINE, TUMOR; CHELATING AGENTS; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; EGTAZIC ACID; ENZYME INDUCTION; INDOLE ALKALOIDS; LIVER; MICE; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN KINASE INHIBITORS; PYRAZOLES; QUINAZOLINES; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; SULFONAMIDES;

EVODIA RUTAECARPA;

EID: 70449674072     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.10.013     Document Type: Article

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