Solid dispersion of rutaecarpine improved its antihypertensive effect in spontaneously hypertensive rats

Biopharmaceutics and Drug Disposition

Volumn 29, Issue 9, 2008, Pages 495-500

  Ding, Jin Song ^a   Gao, Rui ^a   Li, Dai ^a   Peng, Jun ^a   Ran, Li Ling ^a   Li, Yuan Jian ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Anti hypertension; CGRP; Rutaecarpine; SHR; Solid dispersion

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; MESSENGER RNA; RUTAECARPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DOSAGE FORM COMPARISON; DRUG DOSE COMPARISON; DRUG SOLUBILITY; GENE EXPRESSION; HYPERTENSION; NONHUMAN; RAT; SPINAL GANGLION; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CALCITONIN GENE-RELATED PEPTIDE; DOSAGE FORMS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HYPERTENSION; INDOLE ALKALOIDS; QUINAZOLINES; RATS; RATS, INBRED SHR; RNA, MESSENGER; VASODILATOR AGENTS;

EID: 59849092333     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.634     Document Type: Article

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