Induction and inhibition of cytochrome P450-dependent monooxygenases of rats by fungicide bitertanol

Food and Chemical Toxicology

Volumn 44, Issue 12, 2006, Pages 2047-2057

  Chan, Ping Kun ^a   Lu, Shui Yuan ^a,b   Liao, Jiunn Wang ^c   Wei, Chung fan ^a   Tsai, Yiya ^a   Ueng, Tzuu Huei ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAIWAN AGRICULTURAL CHEMICALS AND TOXIC SUBSTANCES RESEARCH INSTITUTE   (Taiwan)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Bitertanol; CYP1A1; CYP2B; CYP3A; Induction; Inhibition

Indexed keywords

3 METHYLCHOLANTHRENE; BENZO[A]PYRENE; BITERTANOL; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 2B; CYTOCHROME P450 3A; ETHOXYRESORUFIN DEETHYLASE; FUNGICIDE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; MESSENGER RNA; PROTEIN; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

AMES TEST; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; IC 50; IMMUNOBLOTTING; KIDNEY; KIDNEY INJURY; LIVER; LIVER INJURY; LIVER MICROSOME; LUNG; LUNG INJURY; MALE; METABOLIC ACTIVATION; MUTAGEN TESTING; NONHUMAN; RAT; RAT STRAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BENZO(A)PYRENE; BIPHENYL COMPOUNDS; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; ENZYME INHIBITORS; FUNGICIDES, INDUSTRIAL; KIDNEY; LIVER; LUNG; MALE; METHYLCHOLANTHRENE; MICROSOMES, LIVER; RATS; RATS, WISTAR; RNA, MESSENGER; SALMONELLA TYPHIMURIUM; TRIAZOLES;

EID: 33749575638     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2006.07.005     Document Type: Article

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