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Volumn 9, Issue 6, 2009, Pages 1410-1417

Clostridium difficile-A continually evolving and problematic pathogen

Author keywords

Clostridium difficile; Clostridium difficile infection (CDI); Comparative phylogenomics; Epidemiology; Food borne zoonotic; Pathogenicity virulence determinants; Typing methods

Indexed keywords

ANTACID AGENT; ANTIBIOTIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; PROTON PUMP INHIBITOR; BACTERIAL DNA; VIRULENCE FACTOR;

EID: 70449652469     PISSN: 15671348     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meegid.2009.06.005     Document Type: Note
Times cited : (51)

References (101)
  • 2
    • 6444227507 scopus 로고    scopus 로고
    • Experimental Clostridium difficile enterocolitis in foals
    • Arroyo L.G., Weese J.S., and Staempfli H.R. Experimental Clostridium difficile enterocolitis in foals. J. Vet. Intern. Med. 18 (2004) 734-738
    • (2004) J. Vet. Intern. Med. , vol.18 , pp. 734-738
    • Arroyo, L.G.1    Weese, J.S.2    Staempfli, H.R.3
  • 3
    • 33846451108 scopus 로고    scopus 로고
    • Molecular analysis of Clostridium difficile isolates recovered from horses with diarrhea
    • Arroyo L.G., Staempfli H., and Weese J.S. Molecular analysis of Clostridium difficile isolates recovered from horses with diarrhea. Vet. Microbiol. 120 (2007) 179-183
    • (2007) Vet. Microbiol. , vol.120 , pp. 179-183
    • Arroyo, L.G.1    Staempfli, H.2    Weese, J.S.3
  • 4
    • 33750033868 scopus 로고    scopus 로고
    • Surface layer proteins from Clostridium difficile induce inflammatory and regulatory cytokines in human monocytes and dendritic cells
    • Ausiello C.M., Cerquetti M., Fedele G., Spensieri F., Palazzo R., Nasso M., Frezza S., and Mastrantonio P. Surface layer proteins from Clostridium difficile induce inflammatory and regulatory cytokines in human monocytes and dendritic cells. Microb. Infect. 8 (2006) 2640-2646
    • (2006) Microb. Infect. , vol.8 , pp. 2640-2646
    • Ausiello, C.M.1    Cerquetti, M.2    Fedele, G.3    Spensieri, F.4    Palazzo, R.5    Nasso, M.6    Frezza, S.7    Mastrantonio, P.8
  • 5
    • 0028271412 scopus 로고
    • Clostridium difficile: history of its role as an enteric pathogen and the current state of knowledge about the organism
    • Bartlett J.G. Clostridium difficile: history of its role as an enteric pathogen and the current state of knowledge about the organism. Clin. Infect. Dis. 18 Suppl. 4 (1994) S265-S272
    • (1994) Clin. Infect. Dis. , vol.18 , Issue.SUPPL. 4
    • Bartlett, J.G.1
  • 6
    • 39749142406 scopus 로고    scopus 로고
    • Historical perspectives on studies of Clostridium difficile and C. difficile infection
    • Bartlett J.G. Historical perspectives on studies of Clostridium difficile and C. difficile infection. Clin. Infect. Dis. 46 Suppl. 1 (2008) S4-11
    • (2008) Clin. Infect. Dis. , vol.46 , Issue.SUPPL. 1
    • Bartlett, J.G.1
  • 8
    • 0030605226 scopus 로고    scopus 로고
    • Definition of the single integration site of the pathogenicity locus in Clostridium difficile
    • Braun V., Hundsberger T., Leukel P., Sauerborn M., and von Eichel-Streiber C. Definition of the single integration site of the pathogenicity locus in Clostridium difficile. Gene 181 (1996) 29-38
    • (1996) Gene , vol.181 , pp. 29-38
    • Braun, V.1    Hundsberger, T.2    Leukel, P.3    Sauerborn, M.4    von Eichel-Streiber, C.5
  • 9
    • 0035436324 scopus 로고    scopus 로고
    • Typing of Clostridium difficile
    • Brazier J.S. Typing of Clostridium difficile. Clin. Microbiol. Infect. 7 (2001) 428-431
    • (2001) Clin. Microbiol. Infect. , vol.7 , pp. 428-431
    • Brazier, J.S.1
  • 10
    • 58149199861 scopus 로고    scopus 로고
    • Distribution and antimicrobial susceptibility patterns of Clostridium difficile PCR ribotypes in English hospitals, 2007-08
    • Brazier J.S., Raybould R., Patel B., Duckworth G., Pearson A., Charlett A., and Duerden B.I. Distribution and antimicrobial susceptibility patterns of Clostridium difficile PCR ribotypes in English hospitals, 2007-08. Euro. Surveill. 13 (2008) 1-5
    • (2008) Euro. Surveill. , vol.13 , pp. 1-5
    • Brazier, J.S.1    Raybould, R.2    Patel, B.3    Duckworth, G.4    Pearson, A.5    Charlett, A.6    Duerden, B.I.7
  • 11
    • 0036302998 scopus 로고    scopus 로고
    • Patterns of sequence conservation in the S-layer proteins and related sequences in Clostridium difficile
    • Calabi E., and Fairweather N. Patterns of sequence conservation in the S-layer proteins and related sequences in Clostridium difficile. J. Bacteriol. 184 (2002) 3886-3897
    • (2002) J. Bacteriol. , vol.184 , pp. 3886-3897
    • Calabi, E.1    Fairweather, N.2
  • 12
    • 35048868078 scopus 로고    scopus 로고
    • Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator
    • Carter G.P., Lyras D., Allen D.L., Mackin K.E., Howarth P.M., O'Connor J.R., and Rood J.I. Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator. J. Bacteriol. 189 (2007) 7290-7301
    • (2007) J. Bacteriol. , vol.189 , pp. 7290-7301
    • Carter, G.P.1    Lyras, D.2    Allen, D.L.3    Mackin, K.E.4    Howarth, P.M.5    O'Connor, J.R.6    Rood, J.I.7
  • 13
    • 27644572105 scopus 로고    scopus 로고
    • Comparative phylogenomics of the food-borne pathogen Campylobacter jejuni reveals genetic markers predictive of infection source
    • Champion O.L., Gaunt M.W., Gundogdu O., Elmi A., Witney A.A., Hinds J., Dorrell N., and Wren B.W. Comparative phylogenomics of the food-borne pathogen Campylobacter jejuni reveals genetic markers predictive of infection source. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 16043-16048
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 16043-16048
    • Champion, O.L.1    Gaunt, M.W.2    Gundogdu, O.3    Elmi, A.4    Witney, A.A.5    Hinds, J.6    Dorrell, N.7    Wren, B.W.8
  • 14
    • 45249086992 scopus 로고    scopus 로고
    • Assessing the role of p-cresol tolerance in Clostridium difficile
    • Dawson L.F., Stabler R.A., and Wren B.W. Assessing the role of p-cresol tolerance in Clostridium difficile. J. Med. Microbiol. 57 (2008) 745-749
    • (2008) J. Med. Microbiol. , vol.57 , pp. 745-749
    • Dawson, L.F.1    Stabler, R.A.2    Wren, B.W.3
  • 15
    • 0035189585 scopus 로고    scopus 로고
    • Pathoadaptive mutations that enhance virulence: genetic organization of the cadA regions of Shigella spp
    • Day Jr. W.A., Fernandez R.E., and Maurelli A.T. Pathoadaptive mutations that enhance virulence: genetic organization of the cadA regions of Shigella spp. Infect. Immun. 69 (2001) 7471-7480
    • (2001) Infect. Immun. , vol.69 , pp. 7471-7480
    • Day Jr., W.A.1    Fernandez, R.E.2    Maurelli, A.T.3
  • 16
    • 34247884411 scopus 로고    scopus 로고
    • Antimicrobial drugs and community-acquired Clostridium difficile-associated disease, UK
    • Delaney J.A., Dial S., Barkun A., and Suissa S. Antimicrobial drugs and community-acquired Clostridium difficile-associated disease, UK. Emerg. Infect. Dis. 13 (2007) 761-763
    • (2007) Emerg. Infect. Dis. , vol.13 , pp. 761-763
    • Delaney, J.A.1    Dial, S.2    Barkun, A.3    Suissa, S.4
  • 17
    • 45249089405 scopus 로고    scopus 로고
    • Antibiotics involved in Clostridium difficile-associated disease increase colonization factor gene expression
    • Deneve C., Delomenie C., Barc M.C., Collignon A., and Janoir C. Antibiotics involved in Clostridium difficile-associated disease increase colonization factor gene expression. J. Med. Microbiol. 57 (2008) 732-738
    • (2008) J. Med. Microbiol. , vol.57 , pp. 732-738
    • Deneve, C.1    Delomenie, C.2    Barc, M.C.3    Collignon, A.4    Janoir, C.5
  • 19
    • 33845351752 scopus 로고    scopus 로고
    • High-level resistance to moxifloxacin and gatifloxacin associated with a novel mutation in gyrB in toxin-A-negative, toxin-B-positive Clostridium difficile
    • Drudy D., Quinn T., O'Mahony R., Kyne L., O'Gaora P., and Fanning S. High-level resistance to moxifloxacin and gatifloxacin associated with a novel mutation in gyrB in toxin-A-negative, toxin-B-positive Clostridium difficile. J. Antimicrob. Chemother. 58 (2006) 1264-1267
    • (2006) J. Antimicrob. Chemother. , vol.58 , pp. 1264-1267
    • Drudy, D.1    Quinn, T.2    O'Mahony, R.3    Kyne, L.4    O'Gaora, P.5    Fanning, S.6
  • 20
    • 34547697437 scopus 로고    scopus 로고
    • Emergence and control of fluoroquinolone resistant, toxin A negative, toxin B positive Clostridium difficile
    • Drudy D., Harnedy N., Fanning S.A., Hannan M., and Kyne L. Emergence and control of fluoroquinolone resistant, toxin A negative, toxin B positive Clostridium difficile. Infect. Control Hosp. Epidemiol. 28 (2007) 932-940
    • (2007) Infect. Control Hosp. Epidemiol. , vol.28 , pp. 932-940
    • Drudy, D.1    Harnedy, N.2    Fanning, S.A.3    Hannan, M.4    Kyne, L.5
  • 21
    • 34247260039 scopus 로고    scopus 로고
    • Isolation and characterisation of toxin A-negative, toxin B-positive Clostridium difficile in Dublin, Ireland
    • Drudy D., Harnedy N., Fanning S., O'Mahony R., and Kyne L. Isolation and characterisation of toxin A-negative, toxin B-positive Clostridium difficile in Dublin, Ireland. Clin. Microbiol. Infect. 13 (2007) 298-304
    • (2007) Clin. Microbiol. Infect. , vol.13 , pp. 298-304
    • Drudy, D.1    Harnedy, N.2    Fanning, S.3    O'Mahony, R.4    Kyne, L.5
  • 23
    • 40749132179 scopus 로고    scopus 로고
    • Use of highly discriminatory fingerprinting to analyze clusters of Clostridium difficile infection cases due to epidemic ribotype 027 strains
    • Fawley W.N., Freeman J., Smith C., Harmanus C., van den Berg R.J., Kuijper E.J., and Wilcox M.H. Use of highly discriminatory fingerprinting to analyze clusters of Clostridium difficile infection cases due to epidemic ribotype 027 strains. J. Clin. Microbiol. 46 (2008) 954-960
    • (2008) J. Clin. Microbiol. , vol.46 , pp. 954-960
    • Fawley, W.N.1    Freeman, J.2    Smith, C.3    Harmanus, C.4    van den Berg, R.J.5    Kuijper, E.J.6    Wilcox, M.H.7
  • 24
    • 56349118809 scopus 로고    scopus 로고
    • Epidemiology of Clostridium difficile-associated disease at University Hospital Basel including molecular characterisation of the isolates 2006-2007
    • Fenner L., Frei R., Gregory M., Dangel M., Stranden A., and Widmer A.F. Epidemiology of Clostridium difficile-associated disease at University Hospital Basel including molecular characterisation of the isolates 2006-2007. Euro. J. Clin. Microbiol. Infect. Dis. 27 (2008) 1201-1207
    • (2008) Euro. J. Clin. Microbiol. Infect. Dis. , vol.27 , pp. 1201-1207
    • Fenner, L.1    Frei, R.2    Gregory, M.3    Dangel, M.4    Stranden, A.5    Widmer, A.F.6
  • 25
    • 0022443783 scopus 로고
    • Lysosomal involvement in cellular intoxication with Clostridium difficile toxin B
    • Florin I., and Thelestam M. Lysosomal involvement in cellular intoxication with Clostridium difficile toxin B. Microb. Pathog. 1 (1986) 373-385
    • (1986) Microb. Pathog. , vol.1 , pp. 373-385
    • Florin, I.1    Thelestam, M.2
  • 26
    • 45249093628 scopus 로고    scopus 로고
    • Glucosylation of Rho GTPases by Clostridium difficile toxin A triggers apoptosis in intestinal epithelial cells
    • Gerhard R., Nottrott S., Schoentaube J., Tatge H., Olling A., and Just I. Glucosylation of Rho GTPases by Clostridium difficile toxin A triggers apoptosis in intestinal epithelial cells. J. Med. Microbiol. 57 (2008) 765-770
    • (2008) J. Med. Microbiol. , vol.57 , pp. 765-770
    • Gerhard, R.1    Nottrott, S.2    Schoentaube, J.3    Tatge, H.4    Olling, A.5    Just, I.6
  • 27
    • 33645761368 scopus 로고    scopus 로고
    • Binary toxin-producing, large clostridial toxin-negative Clostridium difficile strains are enterotoxic but do not cause disease in hamsters
    • Geric B., Carman R.J., Rupnik M., Genheimer C.W., Sambol S.P., Lyerly D.M., Gerding D.N., and Johnson S. Binary toxin-producing, large clostridial toxin-negative Clostridium difficile strains are enterotoxic but do not cause disease in hamsters. J. Infect. Dis. 193 (2006) 1143-1150
    • (2006) J. Infect. Dis. , vol.193 , pp. 1143-1150
    • Geric, B.1    Carman, R.J.2    Rupnik, M.3    Genheimer, C.W.4    Sambol, S.P.5    Lyerly, D.M.6    Gerding, D.N.7    Johnson, S.8
  • 30
    • 0017072355 scopus 로고
    • Clostridium difficile: isolation and characteristics
    • Hafiz S., and Oakley C.L. Clostridium difficile: isolation and characteristics. J. Med. Microbiol. 9 (1975) 129-135
    • (1975) J. Med. Microbiol. , vol.9 , pp. 129-135
    • Hafiz, S.1    Oakley, C.L.2
  • 33
    • 0142011076 scopus 로고    scopus 로고
    • Identification and characterization of a fibronectin-binding protein from Clostridium difficile
    • Hennequin C., Janoir C., Barc M.C., Collignon A., and Karjalainen T. Identification and characterization of a fibronectin-binding protein from Clostridium difficile. Microbiology 149 (2003) 2779-2787
    • (2003) Microbiology , vol.149 , pp. 2779-2787
    • Hennequin, C.1    Janoir, C.2    Barc, M.C.3    Collignon, A.4    Karjalainen, T.5
  • 34
    • 0344447097 scopus 로고    scopus 로고
    • Genomic analysis of Clostridium botulinum group II by pulsed-field gel electrophoresis
    • Hielm S., Björkroth J., Hjjtiä E., and Korkeala H. Genomic analysis of Clostridium botulinum group II by pulsed-field gel electrophoresis. Appl. Environ. Microbiol. 64 2 (1998) 703-708
    • (1998) Appl. Environ. Microbiol. , vol.64 , Issue.2 , pp. 703-708
    • Hielm, S.1    Björkroth, J.2    Hjjtiä, E.3    Korkeala, H.4
  • 36
    • 15544377092 scopus 로고    scopus 로고
    • Generation of an erythromycin-sensitive derivative of Clostridium difficile strain 630 (630Deltaerm) and demonstration that the conjugative transposon Tn916DeltaE enters the genome of this strain at multiple sites
    • Hussain H.A., Roberts A.P., and Mullany P. Generation of an erythromycin-sensitive derivative of Clostridium difficile strain 630 (630Deltaerm) and demonstration that the conjugative transposon Tn916DeltaE enters the genome of this strain at multiple sites. J. Med. Microbiol. 54 (2005) 137-141
    • (2005) J. Med. Microbiol. , vol.54 , pp. 137-141
    • Hussain, H.A.1    Roberts, A.P.2    Mullany, P.3
  • 37
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: biochemistry and biology
    • Jaffe A.B., and Hall A. Rho GTPases: biochemistry and biology. Annu. Rev. Cell Dev. Biol. 21 (2005) 247-269
    • (2005) Annu. Rev. Cell Dev. Biol. , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 38
    • 35048837277 scopus 로고    scopus 로고
    • Cwp84, a surface-associated protein of Clostridium difficile, is a cysteine protease with degrading activity on extracellular matrix proteins
    • Janoir C., Pechine S., Grosdidier C., and Collignon A. Cwp84, a surface-associated protein of Clostridium difficile, is a cysteine protease with degrading activity on extracellular matrix proteins. J. Bacteriol. 189 (2007) 7174-7180
    • (2007) J. Bacteriol. , vol.189 , pp. 7174-7180
    • Janoir, C.1    Pechine, S.2    Grosdidier, C.3    Collignon, A.4
  • 41
    • 34547635096 scopus 로고    scopus 로고
    • Vegetative Clostridium difficile survives in room air on moist surfaces and in gastric contents with reduced acidity: a potential mechanism to explain the association between proton pump inhibitors and C. difficile-associated diarrhea?
    • Jump R.L., Pultz M.J., and Donskey C.J. Vegetative Clostridium difficile survives in room air on moist surfaces and in gastric contents with reduced acidity: a potential mechanism to explain the association between proton pump inhibitors and C. difficile-associated diarrhea?. Antimicrob. Agents. Chemother. 51 (2007) 2883-2887
    • (2007) Antimicrob. Agents. Chemother. , vol.51 , pp. 2883-2887
    • Jump, R.L.1    Pultz, M.J.2    Donskey, C.J.3
  • 43
    • 0029011449 scopus 로고
    • The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins
    • 10.1074/jbc.270.23.13932
    • Just I., Wilm M., Selzer J., Rex G., Eichel-Streiber C.V., Mann M., and Aktories K. The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins. J. Biol. Chem. 270 (1995) 13932-13936 10.1074/jbc.270.23.13932
    • (1995) J. Biol. Chem. , vol.270 , pp. 13932-13936
    • Just, I.1    Wilm, M.2    Selzer, J.3    Rex, G.4    Eichel-Streiber, C.V.5    Mann, M.6    Aktories, K.7
  • 44
    • 0034800006 scopus 로고    scopus 로고
    • Bacterial protein toxins inhibiting low-molecular-mass GTP-binding proteins
    • Just I., Hofmann F., Genth H., and Gerhard R. Bacterial protein toxins inhibiting low-molecular-mass GTP-binding proteins. Int. J. Med. Microbiol. 291 (2001) 243-250
    • (2001) Int. J. Med. Microbiol. , vol.291 , pp. 243-250
    • Just, I.1    Hofmann, F.2    Genth, H.3    Gerhard, R.4
  • 45
    • 0028787845 scopus 로고
    • Microbial recognition of target-cell glycoconjugates
    • Karlsson K.A. Microbial recognition of target-cell glycoconjugates. Curr. Opin. Struct. Biol. 5 (1995) 622-635
    • (1995) Curr. Opin. Struct. Biol. , vol.5 , pp. 622-635
    • Karlsson, K.A.1
  • 46
    • 34250660545 scopus 로고    scopus 로고
    • Prevalence of PCR ribotypes among Clostridium difficile isolates from pigs, calves, and other species
    • Keel K., Brazier J.S., Post K.W., Weese S., and Songer J.G. Prevalence of PCR ribotypes among Clostridium difficile isolates from pigs, calves, and other species. J. Clin. Microbiol. 45 (2007) 1963-1964
    • (2007) J. Clin. Microbiol. , vol.45 , pp. 1963-1964
    • Keel, K.1    Brazier, J.S.2    Post, K.W.3    Weese, S.4    Songer, J.G.5
  • 47
    • 38949178833 scopus 로고    scopus 로고
    • Comparison of seven techniques for typing international epidemic strains of Clostridium difficile: restriction endonuclease analysis, pulsed-field gel electrophoresis, PCR-ribotyping, multilocus sequence typing, multilocus variable-number tandem-repeat analysis, amplified fragment length polymorphism, and surface layer protein A gene sequence typing
    • Killgore G., Thompson A., Johnson S., Brazier J., Kuijper E., Pepin J., Frost E.H., Savelkoul P., Nicholson B., van den Berg R.J., Kato H., Sambol S.P., Zukowski W., Woods C., Limbago B., Gerding D.N., and McDonald L.C. Comparison of seven techniques for typing international epidemic strains of Clostridium difficile: restriction endonuclease analysis, pulsed-field gel electrophoresis, PCR-ribotyping, multilocus sequence typing, multilocus variable-number tandem-repeat analysis, amplified fragment length polymorphism, and surface layer protein A gene sequence typing. J. Clin. Microbiol. 46 (2008) 431-437
    • (2008) J. Clin. Microbiol. , vol.46 , pp. 431-437
    • Killgore, G.1    Thompson, A.2    Johnson, S.3    Brazier, J.4    Kuijper, E.5    Pepin, J.6    Frost, E.H.7    Savelkoul, P.8    Nicholson, B.9    van den Berg, R.J.10    Kato, H.11    Sambol, S.P.12    Zukowski, W.13    Woods, C.14    Limbago, B.15    Gerding, D.N.16    McDonald, L.C.17
  • 48
    • 40749109390 scopus 로고    scopus 로고
    • Increasing prevalence of toxin A-negative, toxin B-positive isolates of Clostridium difficile in Korea: impact on laboratory diagnosis
    • Kim H., Riley T.V., Kim M., Kim C.K., Yong D., Lee K., Chong Y., and Park J.-W. Increasing prevalence of toxin A-negative, toxin B-positive isolates of Clostridium difficile in Korea: impact on laboratory diagnosis. J. Clin. Microbiol. 46 (2008) 1116-1117
    • (2008) J. Clin. Microbiol. , vol.46 , pp. 1116-1117
    • Kim, H.1    Riley, T.V.2    Kim, M.3    Kim, C.K.4    Yong, D.5    Lee, K.6    Chong, Y.7    Park, J.-W.8
  • 49
    • 0036135677 scopus 로고    scopus 로고
    • Molecular fingerprinting of Clostridium difficile isolates: pulsed-field gel electrophoresis versus amplified fragment length polymorphism
    • Klaassen C.H., van Haren H.A., and Horrevorts A.M. Molecular fingerprinting of Clostridium difficile isolates: pulsed-field gel electrophoresis versus amplified fragment length polymorphism. J. Clin. Microbiol. 40 9 (2002) 3546-3547
    • (2002) J. Clin. Microbiol. , vol.40 , Issue.9 , pp. 3546-3547
    • Klaassen, C.H.1    van Haren, H.A.2    Horrevorts, A.M.3
  • 50
    • 34347407844 scopus 로고    scopus 로고
    • Clostridium difficile: changing epidemiology and new treatment options
    • Kuijper E.J., van Dissel J.T., and Wilcox M.H. Clostridium difficile: changing epidemiology and new treatment options. Curr. Opin. Infect. Dis. 20 (2007) 376-383
    • (2007) Curr. Opin. Infect. Dis. , vol.20 , pp. 376-383
    • Kuijper, E.J.1    van Dissel, J.T.2    Wilcox, M.H.3
  • 51
    • 46249085217 scopus 로고    scopus 로고
    • Decreased effectiveness of metronidazole for the treatment of Clostridium difficile infection?
    • Kuijper E.J., and Wilcox M.H. Decreased effectiveness of metronidazole for the treatment of Clostridium difficile infection?. Clin. Infect. Dis. 47 (2008) 63-65
    • (2008) Clin. Infect. Dis. , vol.47 , pp. 63-65
    • Kuijper, E.J.1    Wilcox, M.H.2
  • 52
    • 0018193196 scopus 로고
    • Clostridium difficile and the aetiology of pseudomembranous colitis
    • Larson H.E., Price A.B., Honour P., and Borriello S.P. Clostridium difficile and the aetiology of pseudomembranous colitis. Lancet 1 (1978) 1063-1066
    • (1978) Lancet , vol.1 , pp. 1063-1066
    • Larson, H.E.1    Price, A.B.2    Honour, P.3    Borriello, S.P.4
  • 54
    • 2942594170 scopus 로고    scopus 로고
    • Multilocus sequence typing analysis of human and animal Clostridium difficile isolates of various toxigenic types
    • Lemee L., Dhalluin A., Pestel-Caron M., Lemeland J.-F., and Pons J.-L. Multilocus sequence typing analysis of human and animal Clostridium difficile isolates of various toxigenic types. J. Clin. Microbiol. 42 (2004) 2609-2617
    • (2004) J. Clin. Microbiol. , vol.42 , pp. 2609-2617
    • Lemee, L.1    Dhalluin, A.2    Pestel-Caron, M.3    Lemeland, J.-F.4    Pons, J.-L.5
  • 56
    • 1642483709 scopus 로고    scopus 로고
    • The large resolvase TnpX is the only transposon-encoded protein required for transposition of the Tn4451/3 family of integrative mobilizable elements
    • Lyras D., Adams V., Lucet I., and Rood J.I. The large resolvase TnpX is the only transposon-encoded protein required for transposition of the Tn4451/3 family of integrative mobilizable elements. Mol. Microbiol. 51 (2004) 1787-1800
    • (2004) Mol. Microbiol. , vol.51 , pp. 1787-1800
    • Lyras, D.1    Adams, V.2    Lucet, I.3    Rood, J.I.4
  • 59
    • 34249782307 scopus 로고    scopus 로고
    • Clostridium difficile toxin expression is inhibited by the novel regulator TcdC
    • Matamouros S., England P., and Dupuy B. Clostridium difficile toxin expression is inhibited by the novel regulator TcdC. Mol. Microbiol. 64 (2007) 1274-1288
    • (2007) Mol. Microbiol. , vol.64 , pp. 1274-1288
    • Matamouros, S.1    England, P.2    Dupuy, B.3
  • 62
    • 26944469989 scopus 로고    scopus 로고
    • Variability of Clostridium difficile surface proteins and specific serum antibody response in patients with Clostridium difficile-associated disease
    • Pechine S., Janoir C., and Collignon A. Variability of Clostridium difficile surface proteins and specific serum antibody response in patients with Clostridium difficile-associated disease. J. Clin. Microbiol. 43 (2005) 5018-5025
    • (2005) J. Clin. Microbiol. , vol.43 , pp. 5018-5025
    • Pechine, S.1    Janoir, C.2    Collignon, A.3
  • 64
    • 0031004306 scopus 로고    scopus 로고
    • Production of a complete binary toxin (actin-specific ADP-ribosyltransferase) by Clostridium difficile CD196
    • Perelle S., Gibert M., Bourlioux P., Corthier G., and Popoff M.R. Production of a complete binary toxin (actin-specific ADP-ribosyltransferase) by Clostridium difficile CD196. Infect. Immun. 65 (1997) 1402-1407
    • (1997) Infect. Immun. , vol.65 , pp. 1402-1407
    • Perelle, S.1    Gibert, M.2    Bourlioux, P.3    Corthier, G.4    Popoff, M.R.5
  • 65
    • 45249086113 scopus 로고    scopus 로고
    • Isolation of Clostridium difficile from food animals in Slovenia
    • Pirs T., Ocepek M., and Rupnik M. Isolation of Clostridium difficile from food animals in Slovenia. J. Med. Microbiol. 57 (2008) 790-792
    • (2008) J. Med. Microbiol. , vol.57 , pp. 790-792
    • Pirs, T.1    Ocepek, M.2    Rupnik, M.3
  • 66
    • 56949101780 scopus 로고    scopus 로고
    • Epidemiological study of Clostridium difficile strains isolated in Jean-Verdier-Rene-Muret hospitals from 2001 to 2007
    • Poilane I., Fantinato C., Cruaud P., and Collignon A. Epidemiological study of Clostridium difficile strains isolated in Jean-Verdier-Rene-Muret hospitals from 2001 to 2007. Pathol. Biol. (Paris) 56 (2008) 412-416
    • (2008) Pathol. Biol. (Paris) , vol.56 , pp. 412-416
    • Poilane, I.1    Fantinato, C.2    Cruaud, P.3    Collignon, A.4
  • 69
    • 0034997092 scopus 로고    scopus 로고
    • Rho proteins: linking signaling with membrane trafficking
    • Ridley A.J. Rho proteins: linking signaling with membrane trafficking. Traffic 2 (2001) 303-310
    • (2001) Traffic , vol.2 , pp. 303-310
    • Ridley, A.J.1
  • 70
    • 34848846245 scopus 로고    scopus 로고
    • Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents
    • Riggs M.M., Sethi A.K., Zabarsky T.F., Eckstein E.C., Jump R.L., and Donskey C.J. Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents. Clin. Infect. Dis. 45 (2007) 992-998
    • (2007) Clin. Infect. Dis. , vol.45 , pp. 992-998
    • Riggs, M.M.1    Sethi, A.K.2    Zabarsky, T.F.3    Eckstein, E.C.4    Jump, R.L.5    Donskey, C.J.6
  • 73
    • 0344492211 scopus 로고    scopus 로고
    • New types of toxin A-negative, toxin B-positive strains among Clostridium difficile isolates from Asia
    • Rupnik M., Kato N., Grabnar M., and Kato H. New types of toxin A-negative, toxin B-positive strains among Clostridium difficile isolates from Asia. J. Clin. Microbiol. 41 (2003) 1118-1125
    • (2003) J. Clin. Microbiol. , vol.41 , pp. 1118-1125
    • Rupnik, M.1    Kato, N.2    Grabnar, M.3    Kato, H.4
  • 74
    • 34147093284 scopus 로고    scopus 로고
    • Is Clostridium difficile-associated infection a potentially zoonotic and foodborne disease?
    • Rupnik M. Is Clostridium difficile-associated infection a potentially zoonotic and foodborne disease?. Clin. Microbiol. Infect. 13 (2007) 457-459
    • (2007) Clin. Microbiol. Infect. , vol.13 , pp. 457-459
    • Rupnik, M.1
  • 76
    • 0014229426 scopus 로고
    • Metabolism of phenolic acids by the rat intestinal microflora
    • Scheline R.R. Metabolism of phenolic acids by the rat intestinal microflora. Acta Pharmacol. Toxicol. (Copenh) 26 (1968) 189-205
    • (1968) Acta Pharmacol. Toxicol. (Copenh) , vol.26 , pp. 189-205
    • Scheline, R.R.1
  • 78
    • 0035082791 scopus 로고    scopus 로고
    • p-Hydroxyphenylacetate decarboxylase from Clostridium difficile. A novel glycyl radical enzyme catalysing the formation of p-cresol
    • Selmer T., and Andrei P.I. p-Hydroxyphenylacetate decarboxylase from Clostridium difficile. A novel glycyl radical enzyme catalysing the formation of p-cresol. Euro. J. Biochem. 268 (2001) 1363-1372
    • (2001) Euro. J. Biochem. , vol.268 , pp. 1363-1372
    • Selmer, T.1    Andrei, P.I.2
  • 79
    • 40049090649 scopus 로고    scopus 로고
    • Clostridium difficile and chlorine-releasing disinfectants
    • Settle C.D., and Wilcox M.H. Clostridium difficile and chlorine-releasing disinfectants. Lancet 371 (2008) 810
    • (2008) Lancet , vol.371 , pp. 810
    • Settle, C.D.1    Wilcox, M.H.2
  • 80
    • 50849110800 scopus 로고    scopus 로고
    • Activity of a dry mist hydrogen peroxide system against environmental Clostridium difficile contamination in elderly care wards
    • Shapey S., Machin K., Levi K., and Boswell T.C. Activity of a dry mist hydrogen peroxide system against environmental Clostridium difficile contamination in elderly care wards. J. Hosp. Infect. 70 (2008) 136-141
    • (2008) J. Hosp. Infect. , vol.70 , pp. 136-141
    • Shapey, S.1    Machin, K.2    Levi, K.3    Boswell, T.C.4
  • 81
    • 40749151063 scopus 로고    scopus 로고
    • Emerging toxin A-B+ variant strain of Clostridium difficile responsible for pseudomembranous colitis at a tertiary care hospital in Korea
    • Shin B.-M., Kuak E.Y., Yoo S.J., Shin W.C., and Yoo H.M. Emerging toxin A-B+ variant strain of Clostridium difficile responsible for pseudomembranous colitis at a tertiary care hospital in Korea. Diagn. Microbiol. Infect. Dis. 60 (2008) 333-337
    • (2008) Diagn. Microbiol. Infect. Dis. , vol.60 , pp. 333-337
    • Shin, B.-M.1    Kuak, E.Y.2    Yoo, S.J.3    Shin, W.C.4    Yoo, H.M.5
  • 82
    • 45249104631 scopus 로고    scopus 로고
    • Multicentre study of the prevalence of toxigenic Clostridium difficile in Korea: results of a retrospective study 2000-2005
    • Shin B.M., Kuak E.Y., Yoo H.M., Kim E.C., Lee K., Kang J.O., Whang D.H., and Shin J.H. Multicentre study of the prevalence of toxigenic Clostridium difficile in Korea: results of a retrospective study 2000-2005. J. Med. Microbiol. 57 (2008) 697-701
    • (2008) J. Med. Microbiol. , vol.57 , pp. 697-701
    • Shin, B.M.1    Kuak, E.Y.2    Yoo, H.M.3    Kim, E.C.4    Lee, K.5    Kang, J.O.6    Whang, D.H.7    Shin, J.H.8
  • 83
    • 28844494379 scopus 로고    scopus 로고
    • Clostridium difficile: an important pathogen of food animals
    • Songer J.G., and Anderson M.A. Clostridium difficile: an important pathogen of food animals. Anaerobe 12 (2006) 1-4
    • (2006) Anaerobe , vol.12 , pp. 1-4
    • Songer, J.G.1    Anderson, M.A.2
  • 84
    • 41549142775 scopus 로고    scopus 로고
    • Bile salts and glycine as cogerminants for Clostridium difficile spores
    • Sorg J.A., and Sonenshein A.L. Bile salts and glycine as cogerminants for Clostridium difficile spores. J. Bacteriol. 190 (2008) 2505-2512
    • (2008) J. Bacteriol. , vol.190 , pp. 2505-2512
    • Sorg, J.A.1    Sonenshein, A.L.2
  • 85
    • 0036708347 scopus 로고    scopus 로고
    • Molecular analysis of the pathogenicity locus and polymorphism in the putative negative regulator of toxin production (TcdC) among Clostridium difficile clinical isolates
    • Spigaglia P., and Mastrantonio P. Molecular analysis of the pathogenicity locus and polymorphism in the putative negative regulator of toxin production (TcdC) among Clostridium difficile clinical isolates. J. Clin. Microbiol. 40 (2002) 3470-3475
    • (2002) J. Clin. Microbiol. , vol.40 , pp. 3470-3475
    • Spigaglia, P.1    Mastrantonio, P.2
  • 86
    • 34547597919 scopus 로고    scopus 로고
    • Detection of a genetic linkage between genes coding for resistance to tetracycline and erythromycin in Clostridium difficile
    • Spigaglia P., Barbanti F., and Mastrantonio P. Detection of a genetic linkage between genes coding for resistance to tetracycline and erythromycin in Clostridium difficile. Microb. Drug Resist. 13 (2007) 90-95
    • (2007) Microb. Drug Resist. , vol.13 , pp. 90-95
    • Spigaglia, P.1    Barbanti, F.2    Mastrantonio, P.3
  • 89
    • 45249088074 scopus 로고    scopus 로고
    • Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences
    • Stabler R.A., Dawson L.F., Phua L.T.H., and Wren B.W. Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences. J. Med. Microbiol. 57 (2008) 771-775
    • (2008) J. Med. Microbiol. , vol.57 , pp. 771-775
    • Stabler, R.A.1    Dawson, L.F.2    Phua, L.T.H.3    Wren, B.W.4
  • 90
    • 0032901542 scopus 로고    scopus 로고
    • PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes
    • Stubbs S.L., Brazier J.S., O'Neill G.L., and Duerden B.I. PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes. J. Clin. Microbiol. 37 (1999) 461-463
    • (1999) J. Clin. Microbiol. , vol.37 , pp. 461-463
    • Stubbs, S.L.1    Brazier, J.S.2    O'Neill, G.L.3    Duerden, B.I.4
  • 91
    • 0035189181 scopus 로고    scopus 로고
    • Role of FliC and FliD flagellar proteins of Clostridium difficile in adherence and gut colonization
    • Tasteyre A., Barc M.-C., Collignon A., Boureau H., and Karjalainen T. Role of FliC and FliD flagellar proteins of Clostridium difficile in adherence and gut colonization. Infect. Immun. 69 (2001) 7937-7940
    • (2001) Infect. Immun. , vol.69 , pp. 7937-7940
    • Tasteyre, A.1    Barc, M.-C.2    Collignon, A.3    Boureau, H.4    Karjalainen, T.5
  • 92
    • 0026078094 scopus 로고
    • Toxin A of Clostridium difficile binds to the human carbohydrate antigens I, X, and Y
    • Tucker K.D., and Wilkins T.D. Toxin A of Clostridium difficile binds to the human carbohydrate antigens I, X, and Y. Infect. Immun. 59 (1991) 73-78
    • (1991) Infect. Immun. , vol.59 , pp. 73-78
    • Tucker, K.D.1    Wilkins, T.D.2
  • 93
    • 33746647857 scopus 로고    scopus 로고
    • Clostridium difficile PCR ribotype 027 outbreaks in the Netherlands: recent surveillance data indicate that outbreaks are not easily controlled but interhospital transmission is limited
    • E060126 060122
    • van den Hof S., van der Kooi T., van den Berg R., Kuijper E.J., and Notermans D.W. Clostridium difficile PCR ribotype 027 outbreaks in the Netherlands: recent surveillance data indicate that outbreaks are not easily controlled but interhospital transmission is limited. Euro. Surveill. 11 1 (2006) E060126 060122
    • (2006) Euro. Surveill. , vol.11 , Issue.1
    • van den Hof, S.1    van der Kooi, T.2    van den Berg, R.3    Kuijper, E.J.4    Notermans, D.W.5
  • 95
    • 58749099142 scopus 로고    scopus 로고
    • Clostridium difficile: preventing epidemic outbreaks in home health
    • quiz 570-561
    • Vrtis M.C. Clostridium difficile: preventing epidemic outbreaks in home health. Home Healthc. Nurse 26 (2008) 563-569 quiz 570-561
    • (2008) Home Healthc. Nurse , vol.26 , pp. 563-569
    • Vrtis, M.C.1
  • 97
    • 25144469664 scopus 로고    scopus 로고
    • Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe
    • Warny M., Pepin J., Fang A., Killgore G., Thompson A., Brazier J., Frost E., and McDonald L.C. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet 366 (2005) 1079-1084
    • (2005) Lancet , vol.366 , pp. 1079-1084
    • Warny, M.1    Pepin, J.2    Fang, A.3    Killgore, G.4    Thompson, A.5    Brazier, J.6    Frost, E.7    McDonald, L.C.8
  • 98
    • 56649120585 scopus 로고    scopus 로고
    • Physical and chemical factors influencing the germination of Clostridium difficile spores
    • Wheeldon L.J., Worthington T., Hilton A.C., Elliott T.S., and Lambert P.A. Physical and chemical factors influencing the germination of Clostridium difficile spores. J. Appl. Microbiol. 105 (2008) 2223-2230
    • (2008) J. Appl. Microbiol. , vol.105 , pp. 2223-2230
    • Wheeldon, L.J.1    Worthington, T.2    Hilton, A.C.3    Elliott, T.S.4    Lambert, P.A.5
  • 99
    • 0041519141 scopus 로고    scopus 로고
    • Comparison of the effect of detergent versus hypochlorite cleaning on environmental contamination and incidence of Clostridium difficile infection
    • Wilcox M.H., Fawley W.N., Wigglesworth N., Parnell P., Verity P., and Freeman J. Comparison of the effect of detergent versus hypochlorite cleaning on environmental contamination and incidence of Clostridium difficile infection. J. Hosp. Infect. 54 (2003) 109-114
    • (2003) J. Hosp. Infect. , vol.54 , pp. 109-114
    • Wilcox, M.H.1    Fawley, W.N.2    Wigglesworth, N.3    Parnell, P.4    Verity, P.5    Freeman, J.6
  • 100
    • 0019508815 scopus 로고
    • Production of skatole and para-Cresol by a rumen Lactobacillus sp
    • Yokoyama M.T., and Carlson J.R. Production of skatole and para-Cresol by a rumen Lactobacillus sp. Appl. Environ. Microbiol. 41 (1981) 71-76
    • (1981) Appl. Environ. Microbiol. , vol.41 , pp. 71-76
    • Yokoyama, M.T.1    Carlson, J.R.2
  • 101
    • 60149085427 scopus 로고    scopus 로고
    • High diversity of Clostridium difficile genotypes isolated from a single poultry farm producing replacement laying hens
    • Zidaric V., Zemljic M., Janezic S., Kocuvan A., and Rupnik M. High diversity of Clostridium difficile genotypes isolated from a single poultry farm producing replacement laying hens. Anaerobe 14 (2008) 325-327
    • (2008) Anaerobe , vol.14 , pp. 325-327
    • Zidaric, V.1    Zemljic, M.2    Janezic, S.3    Kocuvan, A.4    Rupnik, M.5


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