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Volumn 13, Issue 3, 2007, Pages 298-304

Isolation and characterisation of toxin A-negative, toxin B-positive Clostridium difficile in Dublin, Ireland

Author keywords

Clostridium difficile; Cytotoxicity assay; ELISA; Molecular characterisation; PCR; Toxins

Indexed keywords

CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B;

EID: 34247260039     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/j.1469-0691.2006.01634.x     Document Type: Article
Times cited : (67)

References (38)
  • 1
    • 0031958706 scopus 로고    scopus 로고
    • Clostridium difficile infection
    • Kelly CP, LaMont JT. Clostridium difficile infection. Annu Rev Med 1998; 49: 375-390.
    • (1998) Annu Rev Med , vol.49 , pp. 375-390
    • Kelly, C.P.1    LaMont, J.T.2
  • 2
    • 0037204196 scopus 로고    scopus 로고
    • Clinical practice. Antibiotic-associated diarrhea
    • Bartlett JG. Clinical practice. Antibiotic-associated diarrhea. N Engl J Med 2002; 346: 334-339.
    • (2002) N Engl J Med , vol.346 , pp. 334-339
    • Bartlett, J.G.1
  • 4
    • 2442464696 scopus 로고    scopus 로고
    • Secular trends in hospital-acquired Clostridium difficile disease in the United States, 1987-2001
    • Archibald LK, Banerjee SN, Jarvis WR. Secular trends in hospital-acquired Clostridium difficile disease in the United States, 1987-2001. J Infect Dis 2004; 189: 1585-1589.
    • (2004) J Infect Dis , vol.189 , pp. 1585-1589
    • Archibald, L.K.1    Banerjee, S.N.2    Jarvis, W.R.3
  • 6
    • 0036192008 scopus 로고    scopus 로고
    • Fulminant Clostridium difficile: An underappreciated and increasing cause of death and complications
    • Dallal RM, Harbrecht BG, Boujoukas AJ et al. Fulminant Clostridium difficile: An underappreciated and increasing cause of death and complications. Ann Surg 2002; 235: 363-372.
    • (2002) Ann Surg , vol.235 , pp. 363-372
    • Dallal, R.M.1    Harbrecht, B.G.2    Boujoukas, A.J.3
  • 7
    • 4444382260 scopus 로고    scopus 로고
    • Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: A changing pattern of disease severity
    • Pepin J, Valiquette L, Alary ME et al. Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: A changing pattern of disease severity. CMAJ 2004; 171: 466-472.
    • (2004) CMAJ , vol.171 , pp. 466-472
    • Pepin, J.1    Valiquette, L.2    Alary, M.E.3
  • 8
    • 25144469664 scopus 로고    scopus 로고
    • Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe
    • Warny M, Pepin J, Fang A et al. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet 2005; 366: 1079-1084.
    • (2005) Lancet , vol.366 , pp. 1079-1084
    • Warny, M.1    Pepin, J.2    Fang, A.3
  • 9
    • 0023175495 scopus 로고
    • Analysis of latex agglutination test for Clostridium difficile toxin A (D-1) and differentiation between C. difficile toxins A and B and latex reactive protein
    • Borriello SP, Barclay FE, Reed PJ, Welch AR, Brown JD, Burdon DW. Analysis of latex agglutination test for Clostridium difficile toxin A (D-1) and differentiation between C. difficile toxins A and B and latex reactive protein. J Clin Pathol 1987; 40: 573-580.
    • (1987) J Clin Pathol , vol.40 , pp. 573-580
    • Borriello, S.P.1    Barclay, F.E.2    Reed, P.J.3    Welch, A.R.4    Brown, J.D.5    Burdon, D.W.6
  • 10
    • 0029802502 scopus 로고    scopus 로고
    • Pathogenesis of Clostridium difficile-associated diarrhoea
    • Pothoulakis C. Pathogenesis of Clostridium difficile-associated diarrhoea. Eur J Gastroenterol Hepatol 1996; 8: 1041-1047.
    • (1996) Eur J Gastroenterol Hepatol , vol.8 , pp. 1041-1047
    • Pothoulakis, C.1
  • 11
    • 0034999642 scopus 로고    scopus 로고
    • Microbes and microbial toxins: Paradigms for microbial-mucosal interactions. II. The integrated response of the intestine to Clostridium difficile toxins
    • Pothoulakis C, Lamont JT. Microbes and microbial toxins: Paradigms for microbial-mucosal interactions. II. The integrated response of the intestine to Clostridium difficile toxins. Am J Physiol Gastrointest Liver Physiol 2001; 280: G178-G183.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.280
    • Pothoulakis, C.1    Lamont, J.T.2
  • 13
    • 0034049543 scopus 로고    scopus 로고
    • Analysis of the pathogenicity locus in Clostridium difficile strains
    • Cohen SH, Tang YJ, Silva J. Analysis of the pathogenicity locus in Clostridium difficile strains. J Infect Dis 2000; 181: 659-663.
    • (2000) J Infect Dis , vol.181 , pp. 659-663
    • Cohen, S.H.1    Tang, Y.J.2    Silva, J.3
  • 14
    • 0030932086 scopus 로고    scopus 로고
    • Characterization of polymorphisms in the toxin A and B genes of Clostridium difficile
    • Rupnik M, Braun V, Soehn F et al. Characterization of polymorphisms in the toxin A and B genes of Clostridium difficile. FEMS Microbiol Lett 1997; 148: 197-202.
    • (1997) FEMS Microbiol Lett , vol.148 , pp. 197-202
    • Rupnik, M.1    Braun, V.2    Soehn, F.3
  • 15
    • 0344492211 scopus 로고    scopus 로고
    • New types of toxin A-negative, toxin B-positive strains among Clostridium difficile isolates from Asia
    • Rupnik M, Kato N, Grabnar M, Kato H. New types of toxin A-negative, toxin B-positive strains among Clostridium difficile isolates from Asia. J Clin Microbiol 2003; 41: 1118-1125.
    • (2003) J Clin Microbiol , vol.41 , pp. 1118-1125
    • Rupnik, M.1    Kato, N.2    Grabnar, M.3    Kato, H.4
  • 16
    • 0031905323 scopus 로고    scopus 로고
    • Isolation of a toxin B-deficient mutant strain of Clostridium difficile in a case of recurrent C. difficile-associated diarrhea
    • Cohen SH, Tang YJ, Hansen B, Silva J. Isolation of a toxin B-deficient mutant strain of Clostridium difficile in a case of recurrent C. difficile-associated diarrhea. Clin Infect Dis 1998; 26: 410-442.
    • (1998) Clin Infect Dis , vol.26 , pp. 410-442
    • Cohen, S.H.1    Tang, Y.J.2    Hansen, B.3    Silva, J.4
  • 17
    • 0026671536 scopus 로고
    • Molecular, immunological, and biological characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile
    • Borriello SP, Wren BW, Hyde S et al. Molecular, immunological, and biological characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile. Infect Immun 1992; 60: 4192-4199.
    • (1992) Infect Immun , vol.60 , pp. 4192-4199
    • Borriello, S.P.1    Wren, B.W.2    Hyde, S.3
  • 18
    • 0025765660 scopus 로고
    • Purification and characterisation of toxin B from a strain of Clostridium difficile that does not produce toxin A
    • Torres JF. Purification and characterisation of toxin B from a strain of Clostridium difficile that does not produce toxin A. J Med Microbiol 1991; 35: 40-44.
    • (1991) J Med Microbiol , vol.35 , pp. 40-44
    • Torres, J.F.1
  • 19
    • 0033914385 scopus 로고    scopus 로고
    • Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile responsible for a nosocomial outbreak of Clostridium difficile-associated diarrhea
    • Alfa MJ, Kabani A, Lyerly D et al. Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile responsible for a nosocomial outbreak of Clostridium difficile-associated diarrhea. J Clin Microbiol 2000; 38: 2706-2714.
    • (2000) J Clin Microbiol , vol.38 , pp. 2706-2714
    • Alfa, M.J.1    Kabani, A.2    Lyerly, D.3
  • 20
    • 0034808952 scopus 로고    scopus 로고
    • Nosocomial outbreak of Clostridium difficile-associated diarrhoea due to a clindamycin-resistant enterotoxin A-negative strain
    • Kuijper EJ, de Weerdt J, Kato H et al. Nosocomial outbreak of Clostridium difficile-associated diarrhoea due to a clindamycin-resistant enterotoxin A-negative strain. Eur J Clin Microbiol Infect Dis 2001; 20: 528-534.
    • (2001) Eur J Clin Microbiol Infect Dis , vol.20 , pp. 528-534
    • Kuijper, E.J.1    de Weerdt, J.2    Kato, H.3
  • 21
    • 0035909092 scopus 로고    scopus 로고
    • Fatal pseudomembranous colitis associated with a variant Clostridium difficile strain not detected by toxin A immunoassay
    • Johnson S, Kent SA, O'Leary KJ et al. Fatal pseudomembranous colitis associated with a variant Clostridium difficile strain not detected by toxin A immunoassay. Ann Intern Med 2001; 135: 434-438.
    • (2001) Ann Intern Med , vol.135 , pp. 434-438
    • Johnson, S.1    Kent, S.A.2    O'Leary, K.J.3
  • 22
    • 0033113360 scopus 로고    scopus 로고
    • An outbreak of toxin A negative, toxin B positive Clostridium difficile-associated diarrhea in a Canadian tertiary-care hospital
    • al-Barrak A, Embil J, Dyck B et al. An outbreak of toxin A negative, toxin B positive Clostridium difficile-associated diarrhea in a Canadian tertiary-care hospital. Can Commun Dis Rep 1999; 25: 65-69.
    • (1999) Can Commun Dis Rep , vol.25 , pp. 65-69
    • al-Barrak, A.1    Embil, J.2    Dyck, B.3
  • 23
    • 0033796981 scopus 로고    scopus 로고
    • Toxin gene analysis of a variant strain of Clostridium difficile that causes human clinical disease
    • Sambol SP, Merrigan MM, Lyerly D, Gerding DN, Johnson S. Toxin gene analysis of a variant strain of Clostridium difficile that causes human clinical disease. Infect Immun 2000; 68: 5480-5487.
    • (2000) Infect Immun , vol.68 , pp. 5480-5487
    • Sambol, S.P.1    Merrigan, M.M.2    Lyerly, D.3    Gerding, D.N.4    Johnson, S.5
  • 24
    • 0037390028 scopus 로고    scopus 로고
    • International typing study of toxin A-negative, toxin B-positive Clostridium difficile variants
    • Johnson S, Sambol SP, Brazier JS et al. International typing study of toxin A-negative, toxin B-positive Clostridium difficile variants. J Clin Microbiol 2003; 41: 1543-1547.
    • (2003) J Clin Microbiol , vol.41 , pp. 1543-1547
    • Johnson, S.1    Sambol, S.P.2    Brazier, J.S.3
  • 25
    • 0031812906 scopus 로고    scopus 로고
    • Genetic rearrangements in the pathogenicity locus of Clostridium difficile strain 8864: Implications for transcription, expression and enzymatic activity of toxins A and B
    • Soehn F, Wagenknecht-Wiesner A, Leukel P et al. Genetic rearrangements in the pathogenicity locus of Clostridium difficile strain 8864: implications for transcription, expression and enzymatic activity of toxins A and B. Mol Gen Genet 1998; 258: 222-232.
    • (1998) Mol Gen Genet , vol.258 , pp. 222-232
    • Soehn, F.1    Wagenknecht-Wiesner, A.2    Leukel, P.3
  • 26
    • 0032780795 scopus 로고    scopus 로고
    • A nonsense mutation abrogates production of a functional enterotoxin A in Clostridium difficile toxinotype VIII strains of serogroups F and X
    • von Eichel-Streiber C, Zec-Pirnat I, Grabnar M, Rupnik M. A nonsense mutation abrogates production of a functional enterotoxin A in Clostridium difficile toxinotype VIII strains of serogroups F and X. FEMS Microbiol Lett 1999; 178: 163-168.
    • (1999) FEMS Microbiol Lett , vol.178 , pp. 163-168
    • von Eichel-Streiber, C.1    Zec-Pirnat, I.2    Grabnar, M.3    Rupnik, M.4
  • 27
    • 0344766074 scopus 로고    scopus 로고
    • A novel cytotoxin from Clostridium difficile serogroup F is a functional hybrid between two other large clostridial cytotoxins
    • Chaves-Olarte E, Low P, Freer E et al. A novel cytotoxin from Clostridium difficile serogroup F is a functional hybrid between two other large clostridial cytotoxins. J Biol Chem 1999; 274: 11046-11052.
    • (1999) J Biol Chem , vol.274 , pp. 11046-11052
    • Chaves-Olarte, E.1    Low, P.2    Freer, E.3
  • 28
    • 0031903191 scopus 로고    scopus 로고
    • Identification of toxin A-negative, toxin B-positive Clostridium difficile by PCR
    • Kato H, Kato N, Watanabe K et al. Identification of toxin A-negative, toxin B-positive Clostridium difficile by PCR. J Clin Microbiol 1998; 36: 2178-2182.
    • (1998) J Clin Microbiol , vol.36 , pp. 2178-2182
    • Kato, H.1    Kato, N.2    Watanabe, K.3
  • 29
    • 0031878772 scopus 로고    scopus 로고
    • A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates
    • Rupnik M, Avesani V, Janc M, von Eichel-Streiber C, Delmee M. A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates. J Clin Microbiol 1998; 36: 2240-2247.
    • (1998) J Clin Microbiol , vol.36 , pp. 2240-2247
    • Rupnik, M.1    Avesani, V.2    Janc, M.3    von Eichel-Streiber, C.4    Delmee, M.5
  • 30
    • 0032901542 scopus 로고    scopus 로고
    • PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes
    • Stubbs SL, Brazier JS, O'Neill GL, Duerden BI. PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes. J Clin Microbiol 1999; 37: 461-463.
    • (1999) J Clin Microbiol , vol.37 , pp. 461-463
    • Stubbs, S.L.1    Brazier, J.S.2    O'Neill, G.L.3    Duerden, B.I.4
  • 31
    • 0035436299 scopus 로고    scopus 로고
    • How to detect Clostridium difficile variant strains in a routine laboratory
    • Rupnik M. How to detect Clostridium difficile variant strains in a routine laboratory. Clin Microbiol Infect 2001; 7: 417-420.
    • (2001) Clin Microbiol Infect , vol.7 , pp. 417-420
    • Rupnik, M.1
  • 32
    • 0031975060 scopus 로고    scopus 로고
    • Multicenter evaluation of the Clostridium difficile TOX A/B TEST
    • Lyerly DM, Neville LM, Evans DT et al. Multicenter evaluation of the Clostridium difficile TOX A/B TEST. J Clin Microbiol 1998; 36: 184-190.
    • (1998) J Clin Microbiol , vol.36 , pp. 184-190
    • Lyerly, D.M.1    Neville, L.M.2    Evans, D.T.3
  • 33
    • 0032816828 scopus 로고    scopus 로고
    • Prevalence of toxin A negative/B positive Clostridium difficile strains
    • Brazier JS, Stubbs SL, Duerden BI. Prevalence of toxin A negative/B positive Clostridium difficile strains. J Hosp Infect 1999; 42: 248-249.
    • (1999) J Hosp Infect , vol.42 , pp. 248-249
    • Brazier, J.S.1    Stubbs, S.L.2    Duerden, B.I.3
  • 34
    • 0036259744 scopus 로고    scopus 로고
    • Prevalence and genetic characterization of toxin A variant strains of Clostridium difficile among adults and children with diarrhea in France
    • Barbut F, Lalande V, Burghoffer B, Thien HV, Grimprel E, Petit JC. Prevalence and genetic characterization of toxin A variant strains of Clostridium difficile among adults and children with diarrhea in France. J Clin Microbiol 2002; 40: 2079-2083.
    • (2002) J Clin Microbiol , vol.40 , pp. 2079-2083
    • Barbut, F.1    Lalande, V.2    Burghoffer, B.3    Thien, H.V.4    Grimprel, E.5    Petit, J.C.6
  • 35
    • 0141528564 scopus 로고    scopus 로고
    • High frequency of antibiotic-associated diarrhea due to toxin A-negative, toxin B-positive Clostridium difficile in a hospital in Japan and risk factors for infection
    • Komatsu M, Kato H, Aihara M et al. High frequency of antibiotic-associated diarrhea due to toxin A-negative, toxin B-positive Clostridium difficile in a hospital in Japan and risk factors for infection. Eur J Clin Microbiol Infect Dis 2003; 22: 525-529.
    • (2003) Eur J Clin Microbiol Infect Dis , vol.22 , pp. 525-529
    • Komatsu, M.1    Kato, H.2    Aihara, M.3
  • 36
    • 0036070029 scopus 로고    scopus 로고
    • High prevalence of toxin A-negative toxin B-positive Clostridium difficile in hospitalized patients with gastrointestinal disease
    • Samra Z, Talmor S, Bahar J. High prevalence of toxin A-negative toxin B-positive Clostridium difficile in hospitalized patients with gastrointestinal disease. Diagn Microbiol Infect Dis 2002; 43: 189-192.
    • (2002) Diagn Microbiol Infect Dis , vol.43 , pp. 189-192
    • Samra, Z.1    Talmor, S.2    Bahar, J.3
  • 37
    • 10744225600 scopus 로고    scopus 로고
    • A European survey of diagnostic methods and testing protocols for Clostridium difficile
    • Barbut F, Delmee M, Brazier JS et al. A European survey of diagnostic methods and testing protocols for Clostridium difficile. Clin Microbiol Infect 2003; 9: 989-996.
    • (2003) Clin Microbiol Infect , vol.9 , pp. 989-996
    • Barbut, F.1    Delmee, M.2    Brazier, J.S.3


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