Hypocretin/orexin increases the expression of steroidogenic enzymes in human adrenocortical NCI H295R cells

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 297, Issue 5, 2009, Pages

  Wenzel, Jan ^a   Grabinski, Nicole ^a   Knopp, Cordula A ^a   Dendorfer, Andreas ^a   Ramanjaneya, Manjunath ^b   Randeva, Harpal S ^b   Ehrhart Bornstein, Monika ^c   Dominiak, Peter ^a   Jöhren, Olaf ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b UNIVERSITY OF WARWICK   (United Kingdom)

^c UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

Cortisol; Hypocretin 1 and 2; OX1 and OX2 receptor; Real time reverse transcriptase polymerase chain reaction

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; CALCIUM; CYCLIC AMP; CYTOCHROME P450; CYTOCHROME P450 11B1; CYTOCHROME P450 17; HYDROCORTISONE; HYDROXYSTEROID DEHYDROGENASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; OREXIN; OREXIN 1 RECEPTOR; OREXIN 2 RECEPTOR; PROTEIN KINASE C; STEROID 11BETA MONOOXYGENASE; STEROID 21 MONOOXYGENASE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ADRENAL CORTEX CELL; ADULT; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HORMONE RELEASE; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; STEROIDOGENESIS; UPREGULATION;

ADRENAL CORTEX; CALCIUM; CELL LINE; CELLS, CULTURED; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROCORTISONE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEUROPEPTIDES; NEUROTRANSMITTER AGENTS; PROGESTERONE REDUCTASE; PROTEIN KINASE C; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; STEROID HYDROXYLASES; STEROIDS;

EID: 70449640252     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.91034.2008     Document Type: Article

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