메뉴 건너뛰기




Volumn 31, Issue 10, 2007, Pages 1605-1616

Human adipocytes induce an ERK1/2 MAP kinases-mediated upregulation of steroidogenic acute regulatory protein (StAR) and an angiotensin II - Sensitization in human adrenocortical cells

Author keywords

Adrenal glands; Aldosterone; Extracellular regulated kinases; Fat cell; Hypertension

Indexed keywords

ADIPOCYTOKINE; ALDOSTERONE; ANGIOTENSIN II; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; STEROIDOGENIC ACUTE REGULATORY PROTEIN;

EID: 34748864760     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/sj.ijo.0803642     Document Type: Article
Times cited : (48)

References (47)
  • 1
    • 0034611791 scopus 로고    scopus 로고
    • Obesity as a medical problem
    • Kopelman PG. Obesity as a medical problem. Nature 2000; 404: 635-643.
    • (2000) Nature , vol.404 , pp. 635-643
    • Kopelman, P.G.1
  • 3
    • 0037340168 scopus 로고    scopus 로고
    • The kidney, hypertension, and obesity
    • Hall JE. The kidney, hypertension, and obesity. Hypertension 2003; 41: 625-633.
    • (2003) Hypertension , vol.41 , pp. 625-633
    • Hall, J.E.1
  • 4
    • 20444461649 scopus 로고    scopus 로고
    • Endothelial dysfunction, cellular adhesion molecules and the metabolic syndrome
    • Schram MT, Stehouwer CD. Endothelial dysfunction, cellular adhesion molecules and the metabolic syndrome. Horm Metab Res 2005; 37S1: 49-55.
    • (2005) Horm Metab Res , vol.37 S1 , pp. 49-55
    • Schram, M.T.1    Stehouwer, C.D.2
  • 7
    • 0028020777 scopus 로고    scopus 로고
    • Egan BM, Stepniakowski K, Goodfriend TL. Renin and aldosterone are higher and the hyperinsulinemic effect of salt restriction greater in subjects with risk factors clustering. Am J Hypertens 1994; 7: 886-893.
    • Egan BM, Stepniakowski K, Goodfriend TL. Renin and aldosterone are higher and the hyperinsulinemic effect of salt restriction greater in subjects with risk factors clustering. Am J Hypertens 1994; 7: 886-893.
  • 8
    • 0028274557 scopus 로고
    • Central obesity and hypertension. Relationship between fasting serum insulin, plasma renin activity, and diastolic blood pressure in young obese subjects
    • Licata G, Scaglione R, Ganguzza A, Corrao S, Donatelli M, Parrinello G et al. Central obesity and hypertension. Relationship between fasting serum insulin, plasma renin activity, and diastolic blood pressure in young obese subjects. Am J Hypertens 1994; 7: 314-320.
    • (1994) Am J Hypertens , vol.7 , pp. 314-320
    • Licata, G.1    Scaglione, R.2    Ganguzza, A.3    Corrao, S.4    Donatelli, M.5    Parrinello, G.6
  • 10
    • 33846386925 scopus 로고    scopus 로고
    • Aldosterone - a hormone of cardiovascular adaptation and maladaptation
    • Goodfriend TL. Aldosterone - a hormone of cardiovascular adaptation and maladaptation. J Clin Hypertens (Greenwich) 2006; 8: 133-139.
    • (2006) J Clin Hypertens (Greenwich) , vol.8 , pp. 133-139
    • Goodfriend, T.L.1
  • 13
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 1999; 341: 709-717.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6
  • 14
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    • Pitt B, Remme W, Zannad F, Neaton J, Martinez F, Roniker B et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med 2003; 348: 1309-1321.
    • (2003) N Engl J Med , vol.348 , pp. 1309-1321
    • Pitt, B.1    Remme, W.2    Zannad, F.3    Neaton, J.4    Martinez, F.5    Roniker, B.6
  • 15
    • 22544466731 scopus 로고    scopus 로고
    • The new biology of aldosterone
    • Connell JM, Davies E. The new biology of aldosterone. J Endocrinol 2005; 186: 1-20.
    • (2005) J Endocrinol , vol.186 , pp. 1-20
    • Connell, J.M.1    Davies, E.2
  • 16
    • 0034896157 scopus 로고    scopus 로고
    • Aldosterone as a determinant of cardiovascular and renal dysfunction
    • Epstein M. Aldosterone as a determinant of cardiovascular and renal dysfunction. J R Soc Med 2001; 94: 378-383.
    • (2001) J R Soc Med , vol.94 , pp. 378-383
    • Epstein, M.1
  • 19
    • 11244311897 scopus 로고    scopus 로고
    • Fat cells may be the obesity-hypertension link: Human adipogenic factors stimulate aldosterone secretion from adrenocortical cells
    • Ehrhart-Bornstein M, Arakelyan K, Krug AW, Scherbaum WA, Bornstein SR. Fat cells may be the obesity-hypertension link: human adipogenic factors stimulate aldosterone secretion from adrenocortical cells. Endocr Res 2004; 30: 865-870.
    • (2004) Endocr Res , vol.30 , pp. 865-870
    • Ehrhart-Bornstein, M.1    Arakelyan, K.2    Krug, A.W.3    Scherbaum, W.A.4    Bornstein, S.R.5
  • 20
    • 12344279935 scopus 로고    scopus 로고
    • Angiotensin II stimulates protein synthesis and inhibits proliferation in primary cultures of rat adrenal glomerulosa cells
    • Otis M, Campbell S, Payet MD, Gallo-Payet N. Angiotensin II stimulates protein synthesis and inhibits proliferation in primary cultures of rat adrenal glomerulosa cells. Endocrinology 2005; 146: 633-642.
    • (2005) Endocrinology , vol.146 , pp. 633-642
    • Otis, M.1    Campbell, S.2    Payet, M.D.3    Gallo-Payet, N.4
  • 21
    • 25444458568 scopus 로고    scopus 로고
    • Mechanisms of extracellularly regulated kinases 1/2 activation in adrenal glomerulosa cells by lysophosphatidic acid and epidermal growth factor
    • Shah BH, Baukal AJ, Shah FB, Catt KJ. Mechanisms of extracellularly regulated kinases 1/2 activation in adrenal glomerulosa cells by lysophosphatidic acid and epidermal growth factor. Mol Endocrinol 2005; 19: 2535-2548.
    • (2005) Mol Endocrinol , vol.19 , pp. 2535-2548
    • Shah, B.H.1    Baukal, A.J.2    Shah, F.B.3    Catt, K.J.4
  • 22
    • 0029809418 scopus 로고    scopus 로고
    • Functional aspects of the effect of prolactin (PRL) on adrenal steroidogenesis and distribution of the PRL receptor in the human adrenal gland
    • Glasow A, Breidert M, Haidan A, Anderegg U, Kelly PA, Bornstein SR. Functional aspects of the effect of prolactin (PRL) on adrenal steroidogenesis and distribution of the PRL receptor in the human adrenal gland. J Clin Endocrinol Metab 1996; 81: 3103-3111.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3103-3111
    • Glasow, A.1    Breidert, M.2    Haidan, A.3    Anderegg, U.4    Kelly, P.A.5    Bornstein, S.R.6
  • 23
    • 0037195911 scopus 로고    scopus 로고
    • Human epidermal growth factor receptor-1 expression renders Chinese hamster ovary cells sensitive to alternative aldosterone signaling
    • Krug AW, Schuster C, Gassner B, Freudinger R, Mildenberger S, Troppmair J et al. Human epidermal growth factor receptor-1 expression renders Chinese hamster ovary cells sensitive to alternative aldosterone signaling. J Biol Chem 2002; 277: 45892-45897.
    • (2002) J Biol Chem , vol.277 , pp. 45892-45897
    • Krug, A.W.1    Schuster, C.2    Gassner, B.3    Freudinger, R.4    Mildenberger, S.5    Troppmair, J.6
  • 26
    • 0028287061 scopus 로고
    • The NCI-H295 cell line: A pluripotent model for human adrenocortical studies
    • Rainey WE, Bird IM, Mason JI. The NCI-H295 cell line: a pluripotent model for human adrenocortical studies. Mol Cell Endocrinol 1994; 100: 45-50.
    • (1994) Mol Cell Endocrinol , vol.100 , pp. 45-50
    • Rainey, W.E.1    Bird, I.M.2    Mason, J.I.3
  • 27
    • 0028944669 scopus 로고
    • Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis
    • Lin D, Sugawara T, Strauss III JF, Clark BJ, Stocco DM, Saenger P et al. Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis. Science 1995; 267: 1828-1831.
    • (1995) Science , vol.267 , pp. 1828-1831
    • Lin, D.1    Sugawara, T.2    Strauss III, J.F.3    Clark, B.J.4    Stocco, D.M.5    Saenger, P.6
  • 28
    • 0032615922 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein
    • Stocco DM. Steroidogenic acute regulatory protein. Vitam Horm 1999; 55: 399-441.
    • (1999) Vitam Horm , vol.55 , pp. 399-441
    • Stocco, D.M.1
  • 29
    • 0030047248 scopus 로고    scopus 로고
    • Regulation of the acute production of steroids in steroidogenic cells
    • Stocco DM, Clark BJ. Regulation of the acute production of steroids in steroidogenic cells. Endocr Rev 1996; 17: 221-244.
    • (1996) Endocr Rev , vol.17 , pp. 221-244
    • Stocco, D.M.1    Clark, B.J.2
  • 30
    • 27644505023 scopus 로고    scopus 로고
    • Multiple signaling pathways regulating steroidogenesis and steroidogenic acute regulatory protein expression: More complicated than we thought
    • Stocco DM, Wang X, Jo Y, Manna PR. Multiple signaling pathways regulating steroidogenesis and steroidogenic acute regulatory protein expression: more complicated than we thought. Mol Endocrinol 2005; 19: 2647-2659.
    • (2005) Mol Endocrinol , vol.19 , pp. 2647-2659
    • Stocco, D.M.1    Wang, X.2    Jo, Y.3    Manna, P.R.4
  • 31
    • 0034457234 scopus 로고    scopus 로고
    • Regulation by adrenocorticotropin (ACTH), angiotensin II, transforming growth factor-beta, and insulin-like growth factor I of bovine adrenal cell steroidogenic capacity and expression of ACTH receptor, steroidogenic acute regulatory protein, cytochrome P450c17, and 3beta-hydroxysteroid dehydrogenase
    • Le Roy C, Li JY, Stocco DM, Langlois D, Saez JM. Regulation by adrenocorticotropin (ACTH), angiotensin II, transforming growth factor-beta, and insulin-like growth factor I of bovine adrenal cell steroidogenic capacity and expression of ACTH receptor, steroidogenic acute regulatory protein, cytochrome P450c17, and 3beta-hydroxysteroid dehydrogenase. Endocrinology 2000; 141: 1599-1607.
    • (2000) Endocrinology , vol.141 , pp. 1599-1607
    • Le Roy, C.1    Li, J.Y.2    Stocco, D.M.3    Langlois, D.4    Saez, J.M.5
  • 32
    • 4444287241 scopus 로고    scopus 로고
    • Phosphorylation and function of the hamster adrenal steroidogenic acute regulatory protein (StAR)
    • Fleury A, Mathieu AP, Ducharme L, Hales DB, Lehoux JG. Phosphorylation and function of the hamster adrenal steroidogenic acute regulatory protein (StAR). J Steroid Biochem Mol Biol 2004; 91: 259-271.
    • (2004) J Steroid Biochem Mol Biol , vol.91 , pp. 259-271
    • Fleury, A.1    Mathieu, A.P.2    Ducharme, L.3    Hales, D.B.4    Lehoux, J.G.5
  • 35
    • 4644293240 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases are involved in the acute activation of steroidogenesis in immature rat Leydig cells by human chorionic gonadotropin
    • Martinelle N, Holst M, Soder O, Svechnikov K. Extracellular signal-regulated kinases are involved in the acute activation of steroidogenesis in immature rat Leydig cells by human chorionic gonadotropin. Endocrinology 2004; 145: 4629-4634.
    • (2004) Endocrinology , vol.145 , pp. 4629-4634
    • Martinelle, N.1    Holst, M.2    Soder, O.3    Svechnikov, K.4
  • 36
    • 0029809348 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinases by gonadotropins and cyclic adenosine 5′-monophosphates in porcine granulosa cells
    • Cameron MR, Foster JS, Bukovsky A, Wimalasena J. Activation of mitogen-activated protein kinases by gonadotropins and cyclic adenosine 5′-monophosphates in porcine granulosa cells. Biol Reprod 1996; 55: 111-119.
    • (1996) Biol Reprod , vol.55 , pp. 111-119
    • Cameron, M.R.1    Foster, J.S.2    Bukovsky, A.3    Wimalasena, J.4
  • 37
    • 0029981232 scopus 로고    scopus 로고
    • A stimulatory role of cyclic adenosine 3′,5′-monophosphate in follicle-stimulating hormone-activated mitogen-activated protein kinase signaling pathway in rat ovarian granulosa cells
    • Das S, Maizels ET, DeManno D, St Clair E, Adam SA, Hunzicker-Dunn M. A stimulatory role of cyclic adenosine 3′,5′-monophosphate in follicle-stimulating hormone-activated mitogen-activated protein kinase signaling pathway in rat ovarian granulosa cells. Endocrinology 1996; 137: 967-974.
    • (1996) Endocrinology , vol.137 , pp. 967-974
    • Das, S.1    Maizels, E.T.2    DeManno, D.3    St Clair, E.4    Adam, S.A.5    Hunzicker-Dunn, M.6
  • 38
    • 0031762010 scopus 로고    scopus 로고
    • Angiotensin II activates mitogen-activated protein kinase via protein kinase C and Ras/Raf-1 kinase in bovine adrenal glomerulosa cells
    • Tian Y, Smith RD, Balla T, Catt KJ. Angiotensin II activates mitogen-activated protein kinase via protein kinase C and Ras/Raf-1 kinase in bovine adrenal glomerulosa cells. Endocrinology 1998; 139: 1801-1809.
    • (1998) Endocrinology , vol.139 , pp. 1801-1809
    • Tian, Y.1    Smith, R.D.2    Balla, T.3    Catt, K.J.4
  • 40
    • 0036669159 scopus 로고    scopus 로고
    • Key role of P38 mitogen-activated protein kinase and the lipoxygenase pathway in angiotensin II actions in H295R adrenocortical cells
    • Natarajan R, Yang DC, Lanting L, Nadler JL. Key role of P38 mitogen-activated protein kinase and the lipoxygenase pathway in angiotensin II actions in H295R adrenocortical cells. Endocrine 2002; 18: 295-301.
    • (2002) Endocrine , vol.18 , pp. 295-301
    • Natarajan, R.1    Yang, D.C.2    Lanting, L.3    Nadler, J.L.4
  • 41
    • 0842269854 scopus 로고    scopus 로고
    • Novel action of activin and bone morphogenetic protein in regulating aldosterone production by human adrenocortical cells
    • Suzuki J, Otsuka F, Inagaki K, Takeda M, Ogura T, Makino H. Novel action of activin and bone morphogenetic protein in regulating aldosterone production by human adrenocortical cells. Endocrinology 2004; 145: 639-649.
    • (2004) Endocrinology , vol.145 , pp. 639-649
    • Suzuki, J.1    Otsuka, F.2    Inagaki, K.3    Takeda, M.4    Ogura, T.5    Makino, H.6
  • 42
    • 33747880805 scopus 로고    scopus 로고
    • cAMP-independent signaling regulates steroidogenesis in mouse Leydig cells in the absence of StAR phosphorylation
    • Manna PR, Chandrala SP, Jo Y, Stocco DM. cAMP-independent signaling regulates steroidogenesis in mouse Leydig cells in the absence of StAR phosphorylation. J Mol Endocrinol 2006; 37: 81-95.
    • (2006) J Mol Endocrinol , vol.37 , pp. 81-95
    • Manna, P.R.1    Chandrala, S.P.2    Jo, Y.3    Stocco, D.M.4
  • 43
    • 0031839731 scopus 로고    scopus 로고
    • Upregulation of human chorionic gonadotrophin-induced steroidogenic acute regulatory protein by insulin-like growth factor-I in rat Leydig cells
    • Lin T, Wang D, Hu J, Stocco DM. Upregulation of human chorionic gonadotrophin-induced steroidogenic acute regulatory protein by insulin-like growth factor-I in rat Leydig cells. Endocrine 1998; 8: 73-78.
    • (1998) Endocrine , vol.8 , pp. 73-78
    • Lin, T.1    Wang, D.2    Hu, J.3    Stocco, D.M.4
  • 44
    • 0036838732 scopus 로고    scopus 로고
    • Mechanisms of epidermal growth factor signaling: Regulation of steroid biosynthesis and the steroidogenic acute regulatory protein in mouse Leydig tumor cells
    • Manna PR, Huhtaniemi IT, Wang XJ, Eubank DW, Stocco DM. Mechanisms of epidermal growth factor signaling: regulation of steroid biosynthesis and the steroidogenic acute regulatory protein in mouse Leydig tumor cells. Biol Reprod 2002; 67: 1393-1404.
    • (2002) Biol Reprod , vol.67 , pp. 1393-1404
    • Manna, P.R.1    Huhtaniemi, I.T.2    Wang, X.J.3    Eubank, D.W.4    Stocco, D.M.5
  • 45
    • 0028130155 scopus 로고
    • Leydig cells: Endocrine, paracrine, and autocrine regulation
    • Saez JM. Leydig cells: endocrine, paracrine, and autocrine regulation. Endocr Rev 1994; 15: 574-626.
    • (1994) Endocr Rev , vol.15 , pp. 574-626
    • Saez, J.M.1
  • 46
    • 20744456715 scopus 로고    scopus 로고
    • Newly discovered endocrine functions of white adipose tissue: Possible relevance in obesity-related diseases
    • Krug AW, Ehrhart-Bornstein M. Newly discovered endocrine functions of white adipose tissue: possible relevance in obesity-related diseases. Cell Mol Life Sci 2005; 62: 1359-1362.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 1359-1362
    • Krug, A.W.1    Ehrhart-Bornstein, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.